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- Host-associated Genetic Differentiation in the Face of Ongoing Gene Flow: Ecological Speciation in a Pathogenic Parasite of Freshwater FishAdaptive evolution in response to varying environments, which leads to population divergence, is one of the most intriguing processes of speciation. However, its effectiveness amidst ongoing gene flow remains controversial. Our study challenges the controversy by analysing population genetic structure, degree of gene flow, and the level of genomic divergence between lineages of a tapeworm parasite (Ligula intestinalis), isolated from different species of fish hosts occurring in sympatry. The parasite, which must overcome the host's immunological defences for a successful infection, has a highly pathogenic impact. Utilising genome-wide Single Nucleotide Polymorphisms (SNPs) and transcriptome data, we investigated whether individual host species impose selection pressures on the parasite populations. Genetic clustering analyses revealed divergence between parasites infecting bream (Abramis brama) and those infecting roach (Rutilus rutilus), bleak (Alburnus alburnus), and rudd (Scardinius erythrophthalmus). Historical demography modelling suggested that the most plausible scenario for this divergence is isolation with continuous gene flow. Selection analysis identified 896 SNPs under selection, exhibiting lower to moderate nucleotide diversity and genetic divergence compared to neutral loci. Transcriptome profiling corroborated these results, revealing distinct gene expression profiles for the two parasite populations. An in-depth examination of the selected SNPs and differentially expressed genes revealed specific genes and their physiological functions, as candidates for the molecular mechanisms of immune evasion and, thus, for driving ecological speciation in the parasite. This study showcases the interplay between host specificity, population demography, and disruptive selection in ecological speciation. By dissecting the genomic factors at play, we gain a better understanding of the mechanisms facilitating population divergence in the presence of gene flow.
- Dataset
- Analyzing Chronic Atrophic Gastritis Research Trends 2014-2024 Based on Bibliometrics and Natural Language ProcessingThe data in the database are supplementary data for the article titled "Analyzing Chronic Atrophic Gastritis Research Trends 2014-2024 Based on Bibliometrics and Natural Language Processing", which mainly include the data contained in the charts and graphs of the article.
- Dataset
- Targeted bile acid metabolomicsTargeted bile acid metabolomics measured major mice bile acids with their respective glycine and taurine conjugates.
- Dataset
- LINF_200005100WD40 repeat-containing protein; Leishmania infantum (strain JPCM5)
- Dataset
- Early intervention as preventive treatment in patients with class III malocclusion.This database contains data extraction from a systematic review of the treatment of choice for skeletal Class III patients aged 6 to 11 years
- Dataset
- Friend or foe? Revealing the omnivorous feeding behavior of the ring-legged earwig on brassicasThis study examined the hypothesis that the herbivory of Euborellia annulipes positively affects its biological traits, with variations based on the cultivated species of Brassica and the availability of essential food sources. The provision of plant material (leaf pieces) from the Brassica species pak choi cabbage, Portuguese cabbage, cabbage, and radish did not improve the biological performance of the earwig compared to a diet without plant material. Nevertheless, 66.0% and 43.3% of the second instar nymphs that solely consumed pak choi cabbage and Portuguese cabbage, respectively, completed their development successfully. Herbivory by E. annulipes on brassicas occurred both in the presence and absence of a diet, although it was significantly more pronounced when no other food sources were available. Among the four Brassica species studied, pak choi cabbage exhibited the highest feeding frequency and consumption rate. However, pak choi cabbage grown under controlled conditions and exposed to multiple releases of earwigs showed no reduction in productivity.
- Dataset
- Floating peat mat formation in northern pond of the Xingkai LakeIn this data set, we shown the formation age of the floating peat mat, the dry bulk density, carbon, nutrients (TN, TP, TK), and typical carbon compounds obtained through FTIR spectrum (carbohydrate and aromatic) of the selected peat core in studied floating peat mat.
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- “Sometimes They Ask Me Directly: Madam, Are You Expecting?” Experiences of Teacher-MothersThis dataset includes transcription of interviews with teacher-mothers about their experiences of teaching and being a mother. There is a total of 12 interviews in the dataset.
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- Data: Exploring energy productivity and low carbon economies among renewable energy penetration in the European UnionData
- Dataset
- Supplementary files for "Oral tofacitinib in comparison with dexamethasone oral mini pulse therapy for the treatment of active non-segmental vitiligo: A randomized controlled trial"This dataset includes supplementary files for the publication "Title: Oral tofacitinib in comparison with dexamethasone oral mini pulse therapy for the treatment of active non-segmental vitiligo: A randomized controlled trial". This comprises pre and post treatment images from both the treatment arms and graphs depicting the improvement with treatment.
- Dataset
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