Assessing the performance of real-time epidemic forecasts: A case study of Ebola in the Western Area Region of Sierra Leone, 2014-15
Contributors: Funk, S, Camacho, A, Kucharski, AJ, Lowe, R, Eggo, RM, Edmunds, WJ
Extremely Low Hepatitis C prevalence among HIV co-infected individuals in 4 countries in sub-Saharan Africa
Contributors: Loarec, A, Carnimeo, V, Molfino, L, Kizito, W, Muyindike, W, Andrieux-Meyer, I, Balkan, S, Nzomukunda, Y, Mwanga-Amumpaire, J, Ousley, J
... : A multicentric, retrospective case-series analysis (facility-based) in five sites across Kenya, Malawi, Mozambique, and Uganda screened HIV-positive adults for hepatitis C virus (HCV) antibodies using Oraquick rapid testing and viral confirmation (in three sites). Results found substantially lower prevalence than previously reported for these countries compared with previous reports, suggesting that targeted integration of HCV screening in African HIV programs may be more impactful than routine screening.This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0.
Field suitability and diagnostic accuracy of the Biocentric open real-time PCR platform for plasma-based HIV viral load quantification in Swaziland
Contributors: Kerschberger, B, Mpala, Q, Uribe, PAD, Maphalala, G, de la Tour, R, Kalombola, S, Bekele, A, Chawinga, T, Mliba, M, Ntshalintshali, N
... Viral load (VL) testing is being scaled up in resource-limited settings. However, not all commercially available VL testing methods have been evaluated under field conditions. This study is one of a few to evaluate the Biocentric platform for VL quantification in routine practice in Sub-Saharan Africa.
Top results from Data Repository sources. Show only results like these.
Barriers to access to visceral leishmaniasis diagnosis and care among seasonal mobile workers in Western Tigray, Northern Ethiopia: A qualitative study
Contributors: Coulborn, RM, Gebrehiwot, TG, Schneider, M, Gerstl, S, Adera, C, Herrero, M, Porten, K, den Boer, M, Ritmeijer, K, Alvar, J
... Ethiopia bears a high burden of visceral leishmaniasis (VL). Early access to VL diagnosis and care improves clinical prognosis and reduces transmission from infected humans; however, significant obstacles exist. The approximate 250,000 seasonal mobile workers (MW) employed annually in northwestern Ethiopia may be particularly disadvantaged and at risk of VL acquisition and death. Our study aimed to assess barriers, and recommend interventions to increase access, to VL diagnosis and care among MWs.
Retention in care among clinically stable antiretroviral therapy patients following a six-monthly clinical consultation schedule: findings from a cohort study in rural Malawi
Contributors: Wringe, A, Cawley, C, Szumilin, E, Salumu, L, Amoros Quiles, I, Pasquier, E, Masiku, C, Nicholas, S
... Longer intervals between clinic consultations for clinically stable antiretroviral therapy (ART) patients may improve retention in care and reduce facility workload. We assessed long-term retention among clinically stable ART patients attending six-monthly clinical consultations (SMCC) with three-monthly fast-track drug refills, and estimated the number of consultations "saved" by this model of ART delivery in rural Malawi.
Contributors: Das, D, Grais, R F, Okiro, E A, Stepniewska, K, Mansoor, R, van der Kam, S, Terlouw, D J, Tarning, J, Barnes, K I, Guerin, P J
... Despite substantial improvement in the control of malaria and decreased prevalence of malnutrition over the past two decades, both conditions remain heavy burdens that cause hundreds of thousands of deaths in children in resource-poor countries every year. Better understanding of the complex interactions between malaria and malnutrition is crucial for optimally targeting interventions where both conditions co-exist. This systematic review aimed to assess the evidence of the interplay between malaria and malnutrition.
Removal of user fees and system strengthening improves access to maternity care, maternal and neonatal mortality in a district hospital in Lesotho
Contributors: Steele, SJ, Sugianto, H, Baglione, Q, Sedlimaier, S, Niyibizi, AA, Duncan, K, Hill, J, Brix, J, Philips, M, Van Cutsem, G
... Lesotho has one of the highest maternal mortality rates in the world. While at primary health care (PHC) level maternity care is free, at hospital level co-payments are required from patients. We describe service utilisation and delivery outcomes before and after removal of user fees and quality of delivery care, and associated costs, at St Joseph's Hospital (SJH) in Roma, Lesotho.
High treatment success rate for multidrug-resistant and extensively drug-resistant tuberculosis using a bedaquiline-containing treatment regimen
Contributors: Ndjeka, N, Schnippel, K, Master, I, Meintjes, G, Maartens, G, Romero, R, Padanilam, X, Enwerem, M, Chotoo, S, Singh, N
... We regret that this article is behind a paywall.
Uncharted territory of the epidemiological burden of cutaneous leishmaniasis in sub-Saharan Africa-A systematic review
Contributors: Sunyoto, T, Verdonck, K, El Safi, S, Potet, J, Picado, A, Boelaert, M
... Cutaneous leishmaniasis (CL) is the most frequent form of leishmaniasis, with 0.7 to 1.2 million cases per year globally. However, the burden of CL is poorly documented in some regions. We carried out this review to synthesize knowledge on the epidemiological burden of CL in sub-Saharan Africa.