Data for: Predicting missing links in directed networks based on local structure: An investment-profit index
Contributors: Jinsong Li, Shuxin Liu
... This dataset contains all necessary data, program files and raw results of our manuscript "Predicting missing links in directed networks based on local structure: An investment-profit index".
Contributors: Jens Kalchschmidt
... These are the raw data files of the 2nd allele targeting experiments, the Med14 SMASh and PolII alpha-amanitin western blots published in El Khattabi et al., Cell, 2019
Contributors: Meilin Fernandez Garcia, Kenneth Zaret
Top results from Data Repository sources. Show only results like these.
Contributors: Joshua Soderholm
... The following collection is used to demonstrate the HailPixel survey technique as part of an AGU GRL publication. The following is an abstract for this paper: A new technique, named "HailPixel," is introduced for measuring the maximum dimension and intermediate dimension of hailstones from aerial imagery. The photogrammetry procedure applies a convolutional neural network for robust detection of hailstones against complex backgrounds and an edge detection method for measuring the shape of identified hailstones. This semi-automated technique is capable of measuring many thousands of hailstones within a single survey, which is several orders of magnitude larger than population sizes from existing sensors (e.g., a hail pad). Comparison with a co-located hail pad for an Argentinan hailstorm event demonstrates the larger population size of the HailPixel survey significantly improves the shape and tails of the observed hail size distribution. When hailfall is sparse, such as during large and giant hail events, the large survey area of this technique is especially advantageous for resolving the hail size distribution. The dataset contains the DEM and orthomosaic imagery, processing reports, final location of hail centroids, final measurements of hail major and minor axis, subset offsets and hail pad data. For more information applying the subset offsets to calculate the true position of the hail centroids please see the paper.
Data for: Calreticulin stabilizes F-actin by acetylating actin and protects microvascular endothelial cells against microwave radiation
Contributors: Xiuhua Liu
... Effects of microwave radiation and CRT incubation on F-actin arrangement in HMECs. We evaluated the actin cytoskeleton and demonstrated that high-power microwave radiation inhibited actin polymerization, thus disrupting the F-actin arrangement.
Data for: A geomorphology based reconstruction of ice volume distribution at the Last Glacial Maximum across the Southern Alps of New Zealand
Contributors: William James, Duncan Quincey, Jonathan Carrivick, Neil Glasser
... Modeled LGM ice thickness for the New Zealand Southern Alps
Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
Contributors: Jian Hui Low, Pin Li, Elaine Chew, Bingrui Zhou, Tian Zhang, Michelle Lian, Meng Liu, Jia Nee Foo, Juan Carlos Izpisua Belmonte, Yun Xia
... Human pluripotent stem cells-derived kidney organoids recapitulate developmental processes and tissue architectures, but intrinsic limitations, such as a lack of vasculature and functionality, have greatly hampered their application. Here we establish a versatile protocol for generating vascularized three-dimensional kidney organoids. We employ dynamic modulation of WNT signaling to control the relative proportion of proximal versus distal nephron segments, thereby producing a correlative level of VEGFA to define a resident vascular network. Single cell RNA-sequencing identifies a subset of nephron progenitor cells as a potential source of renal vasculature. These kidney organoids undergo further structural and functional maturation upon implantation. Using this kidney organoid platform, we establish an in vitro model of autosomal recessive polycystic kidney disease, the cystic phenotype of which can be effectively prevented by gene correction or drug treatment. Our studies provide new avenues for studying human kidney development, modeling disease pathogenesis, and performing patient-specific drug validation.
Data for: Enhanced Stability and Efficacy of GEM-TOS Prodrug by Co-assembly with Antimetastatic Shell LMWH-TOS
Contributors: Qin He, Penghui He, Miao Deng, Rong Guo, Yang Long, Man Li, Zhengze Lu
... Enhanced Stability and Efficacy of GEM-TOS Prodrug by Co-assembly with Antimetastatic Shell LMWH-TOS
Contributors: Shih-Chieh Ti
... We run about 5 μg of recombinant human a1B/b2B-tubulin on a 4-20% Tris-Glycine SDS-PAGE gel. The tubulin band is excised, reduced, alkylated, trypsinized, and analyzed by tandem LC-MS/MS.
Contributors: Shih-Chieh Ti
... Recombinant human a1B/b3-tubulin was purified from High Five insect cells. We run about 5 μg of protein on a 4-20% Tris-Glycine SDS-PAGE gel. The tubulin band is excised, reduced, alkylated, trypsinized, and analyzed by tandem LC-MS/MS.