Contributors: Nickolas Hawkes, Michelle Korabik, Lindsay Beazley, Hans Tore Rapp, Joana Xavier, Ellen Kenchington
... Emerald Basin on the Scotia Shelf off Nova Scotia, Canada, is home to a globally unique population of the glass sponge Vazella pourtalesi. Through the analysis of both in situ photographs and trawl catch data from annual multispecies bottom-trawl surveys, we examined community composition, species density, and abundance of epibenthos and fish associated with V. pourtalesi compared to locations without this sponge. Using generalized linear models and analysis of similarities, the importance of V. pourtalesi in enhancing species density and abundance of the associated epibenthic community was assessed against that of the hard substrate on which it settles. Our results indicated that the megafaunal assemblage associated with V. pourtalesi was significantly different in composition and higher in species density and abundance compared to locations without V. pourtalesi. Analysis of similarity of trawl catch data indicated that fish communities associated with the sponge grounds are significantly different from those without V. pourtalesi, although no species were found exclusively on the sponge grounds. Our study provides further evidence of the role played by sponge grounds in shaping community structure and biodiversity of associated deep-sea epibenthic and fish communities. The mechanism for biodiversity enhancement within the sponge grounds formed by V. pourtalesi is likely the combined effect of both the sponge itself and its attachment substrate, which together comprise the habitat of the sponge grounds. We also discuss the role of habitat provision between the mixed-species tetractinellid sponges of the Flemish Cap and the monospecific glass sponge grounds of Emerald Basin. Please refer to the following citation for additional details on the data: Hawkes N, Korabik M, Beazley L, Rapp HT, Xavier JR, Kenchington E (2019) Glass sponge grounds on the Scotian Shelf and their associated biodiversity. Mar Ecol Prog Ser 614:91-109. https://doi.org/10.3354/meps12903
Contributors: Patricia Davidson
... Data obtained and analyzed for a manuscript on GFP-nesprin-2 accumulation. Excel files with the data and information on the validation of the CRISPR modification.
Contributors: Benjamin Adam, Julie Tucker, Graham Tewksbury
... Gleeble iso-T true stress-strain data at 1000C-1200C in 50C steps for 0.01/s - 1/s; EBSD IPF and BC of geometric centers of sectioned samples; ThermoCalc 2015 calculated property diagrams for stable phases and data tables with compositional changes vs. T for all phases
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Contributors: Ines Diaz-Laviada, Belen Sanchez, Alicia Bort, Pedro Mateos, Nieves Rodríguez-Henche
... Data used to generate figures of the paper “Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase” Sánchez BG, Bort A, Mateos-Gómez PA, Rodríguez-Henche N, Díaz-Laviada I. Cancer Cell Int. 2019 Mar 8;19:54. doi: 10.1186/s12935-019-0769-2. eCollection 2019. In this study we demonstrate that the spicy ingredient of peepers, capsaicin, sensitizes prostate cancer cell to docetaxel. The metabolic regulator AMPK plays a pivotal role.
Overexpression of AMP-activated kinase sensitizes Sorafenib-resistant Hepatocellular cancer cells and decreases stem cell markers
Contributors: Ines Diaz-Laviada
... Data used to generate figures of the paper by Bort A, Sánchez BG, Mateos-Gómez PA, Vara-Ciruelos D, Rodríguez-Henche N, Díaz-Laviada I. “Targeting AMP-activated kinase impacts hepatocellular cancer stem cells induced by long-term treatment with sorafenib” Mol Oncol. 2019 May;13(5):1311-1331. doi: 10.1002/1878-0261.12488. In this study we demonstrate that the AMP-activated kinase AMPK reverse the Cancer Stem cell features of Hepatocellular CSC.
Contributors: Fan Fan
... Raw data for PET-PCL blends
Data set of master thesis Applying the Requirements Engineering for Software Architecture model in software products: a case study using crowdsourcing
Contributors: Abel Menkveld
... Data gathered, used and/or analyzed for the Business Informatics Master Thesis "Applying the Requirements Engineering for Software Architecture model in software products: a case study using crowdsourcing", performed at Utrecht University.
Data for: Endothelial cell glucose metabolism is modulated by the flavonoid quercetin through actions on HIF1a signaling and energy regulating genes
Contributors: Gary Williamson, Asimina Kerimi, Sarka Tumova
... Data showing changes in HUVECs after treatment with quercetin or DMOG and assessment of gene expression, glucose uptake and protein expression.
Contributors: Luca Iandoli
... The data have been used to test the following research hypotheses H1: Perceived Elegance is inversely correlated to expected effort; H2: Perceived Elegance is positively correlated with the EC of a product interface. H3: Elegance is positively correlated to the actual effort of using a new product. Perceived was elegance was measured through an online survey (see survey) in which participants were asked to rank several models of an appliance control panel in order of perceived elegance using a one to 5 scale (1 most elegant, 5 least elegant) Expected effort was measured through an online survey (see survey) in which participants were asked to rank several models of an appliance control panel in order of perceived elegance using a one to 5 scale (the easiest to use) to 5 ( the hardest to use) Effective complexity is a metric described in the file Microwave EC.ppt. The EC value is computed based on the spatial organization of control elements on the panel (knobs, buttons, screens, etc.). Actual effort was measured through total execution time of the three tasks by every participant, including possible mistakes and subsequent new attempts. The Kruskal Wallis test and post hoc test are reported in the data actual effort folder
Regional heterogeneity in gene expression, regulation and coherence in hippocampus and prefrontal cortex across development and in schizophrenia. Collado-Torres et al, Neuron, 2019.
Contributors: Leonardo Collado-Torres, Emily E Burke, Amy Peterson, Joo Heon Shin, Richard Straub, Nina Rajpurohit, Stephen A Semick, William S Ulrich, BrainSeq Consortium, Amanda J Price
... This dataset contains the Supplementary Figures and Tables for the "Regional heterogeneity in gene expression, regulation and coherence in hippocampus and prefrontal cortex across development and in schizophrenia" article by Collado-Torres et al, Neuron, 2019. Please cite the original article as well as the data itself if appropriate. For clarifications about the figures or data, please contact us by creating an issue at https://github.com/LieberInstitute/brainseq_phase2/issues. Thank you!