Regional heterogeneity in gene expression, regulation and coherence in hippocampus and prefrontal cortex across development and in schizophrenia. Collado-Torres et al, Neuron, 2019.
Contributors: Leonardo Collado-Torres, Emily E Burke, Amy Peterson, Joo Heon Shin, Richard Straub, Nina Rajpurohit, Stephen A Semick, William S Ulrich, BrainSeq Consortium, Amanda J Price
... This dataset contains the Supplementary Figures and Tables for the "Regional heterogeneity in gene expression, regulation and coherence in hippocampus and prefrontal cortex across development and in schizophrenia" article by Collado-Torres et al, Neuron, 2019. Please cite the original article as well as the data itself if appropriate. For clarifications about the figures or data, please contact us by creating an issue at https://github.com/LieberInstitute/brainseq_phase2/issues. Thank you!
Contributors: Petter Ström, Per Petersson, Anna Widdowson, Gennady Sergienko, Elżbieta Fortuna-Zaleśna, Marek Rubel
... ToF-ERDA data with partial GIC energy signals from QMB covers 1,2,3,5 (ILW-1-2). Data provided as list-files (.lst) and histogram files (.mpa) from FAST MPA-3 data acquisition system. ADC 1: Energy signal anode 1. ADC 2: Energy signal anodes 2-4. ADC 3: ToF signal.
Contributors: Philipp Keller
... Guide's software and data repository- compact version
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Contributors: Philipp Keller
... Guide's software and data repository- full version
Contributors: Gabriel Fiorin, Andrea Sanchez-Vallet , Daniela Thomazella, Paula Prado, Leandro Nascimento, Antonio Figueira, Bart Thomma, Goncalo Pereira, Paulo Teixeira
... Source data of the paper "Suppression of plant immunity by fungal chitinase-like effectors".
Contributors: Saroj Chakraborty
... Salt-responsive Metabolite, beta-hydroxybutyrate, Attenuates Hypertension Chakraborty, S1, Galla, S1, Cheng X1, Yeo, J1, Mell, B1, Singh V1, Yeoh BS1, Saha P1, Mathew, AV2, Vijay-Kumar, M1, Joe B*1. 1Program in Physiological Genomics, Microbiome Consortium, Center for Hypertension and Personalized Medicine, Department of Physiology and Pharmacology, University of Toledo College of Medicine and Life Sciences, Toledo, OH, USA. 2 Department of Internal Medicine-Nephrology, University of Michigan, Ann Arbor, MI, USA. *Corresponding Author: Bina Joe, firstname.lastname@example.org Summary Dietary salt reduction and exercise are lifestyle modifications prescribed for salt-sensitive hypertensives. While exercise is known to have prominent metabolic effects, such effects of lower dietary salt are just emerging. Studies indicate that salt has adverse effect on metabolic syndrome, of which, hypertension is a hallmark. We hypothesized that dietary salt impacts metabolism in a salt-sensitive model of hypertension. Untargeted metabolomic profiling of rats with differential salt (NaCl) diets revealed that a high salt-induced increase in blood pressure was associated with lower circulating levels of the ketone body, beta-hydroxybutyrate (βOHB). Specific rescue of the βOHB levels by nutritional supplementation of its precursor, 1,3-butanediol attenuated hypertension and protected kidney disease despite the high salt intake. This beneficial effect of βOHB was observed independent of the gut-microbiotal effects of salt or the Th17-mediated renal effects. Instead, the mechanism for the observed renoprotective effect of βOHB on salt-sensitive hypertension was the βOHB-mediated inhibition of the pro-inflammatory cascade by the Nlrp3 inflammasome. In summary, the juxtaposed effects of dietary salt and exercise on salt-sensitive hypertension, which decrease and increase βOHB respectively, indicates that nutritional supplementation of a precursor of βOHB could be considered to provide a similar benefit to salt-sensitive hypertension as exercise.
Contributors: Daniel Sorensen
... Raw data set for Vit 105 to titanium laser weld manuscript
Data for: Virtual Nondestructive Evaluation of Anisotropic Plates by Implementing Symmetry Informed Sequential Mapping of Anisotropic Green’s function (SISMAG)
Contributors: Sourav Banerjee, Sajan Shrestha
... No data should be used without permission from the corresponding the author. With permission, data can be used for only non-commercial purposes.
Raw images for defective replication stress response is inherently linked to the cancer stem cell phenotype
Contributors: Daniel McGrail
... Raw images/blots for "Defective replication stress response is inherently linked to the cancer stem cell phenotype"
Contributors: Edoardo Paluan
... The aim of the project is to create an optical interferometer which can detect the acoustic analogue of a supernova explosion. The fingerprint of an acoustic wave propagating from a diapason will be measured. A Michelson Morley interferometer1 will be used, whereby analysis of the interference pattern will allow for the calculation of the frequency of the diapason.