Contributors: Ines Diaz-Laviada, Belen Sanchez, Alicia Bort, Pedro Mateos, Nieves Rodríguez-Henche
... Data used to generate figures of the paper “Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase” Sánchez BG, Bort A, Mateos-Gómez PA, Rodríguez-Henche N, Díaz-Laviada I. Cancer Cell Int. 2019 Mar 8;19:54. doi: 10.1186/s12935-019-0769-2. eCollection 2019. In this study we demonstrate that the spicy ingredient of peepers, capsaicin, sensitizes prostate cancer cell to docetaxel. The metabolic regulator AMPK plays a pivotal role.
Overexpression of AMP-activated kinase sensitizes Sorafenib-resistant Hepatocellular cancer cells and decreases stem cell markers
Contributors: Ines Diaz-Laviada
... Data used to generate figures of the paper by Bort A, Sánchez BG, Mateos-Gómez PA, Vara-Ciruelos D, Rodríguez-Henche N, Díaz-Laviada I. “Targeting AMP-activated kinase impacts hepatocellular cancer stem cells induced by long-term treatment with sorafenib” Mol Oncol. 2019 May;13(5):1311-1331. doi: 10.1002/1878-0261.12488. In this study we demonstrate that the AMP-activated kinase AMPK reverse the Cancer Stem cell features of Hepatocellular CSC.
Virtual outcrop geology comes of age: the application of consumer-grade virtual reality hardware and software to digital outcrop data analysis
Contributors: Thomas Seers, Ali Sheharyar
... In this work, the need for discipline specific analysis tools is addressed by harnessing a consumer grade virtual reality system (HTC Vive) and freeform 3D visual arts software package (Google Tilt Brush) to interactively interpret and analyze sedimentary and structural architecture (bedding contacts, faults, fractures) from digital outcrop models. Having generated these interpretations, users utilize a script library developed in the MATLABTM language to extract geologically useful data (e.g. orientation, length, intensity) from interactively generated 3D mesh patches output by Tilt Brush. Note that the submission contains the MATLAB code library, test data and presentation (.ppt) with videoed examples of Tilt Brush data input and interpretation.
Contributors: Fan Fan
... Raw data for PET-PCL blends
Contributors: Qi Cheng
... Data for this research
Data set of master thesis Applying the Requirements Engineering for Software Architecture model in software products: a case study using crowdsourcing
Contributors: Abel Menkveld
... Data gathered, used and/or analyzed for the Business Informatics Master Thesis "Applying the Requirements Engineering for Software Architecture model in software products: a case study using crowdsourcing", performed at Utrecht University.
Data for: Endothelial cell glucose metabolism is modulated by the flavonoid quercetin through actions on HIF1a signaling and energy regulating genes
Contributors: Gary Williamson, Asimina Kerimi, Sarka Tumova
... Data showing changes in HUVECs after treatment with quercetin or DMOG and assessment of gene expression, glucose uptake and protein expression.
Contributors: Luca Iandoli
... The data have been used to test the following research hypotheses H1: Perceived Elegance is inversely correlated to expected effort; H2: Perceived Elegance is positively correlated with the EC of a product interface. H3: Elegance is positively correlated to the actual effort of using a new product. Perceived was elegance was measured through an online survey (see survey) in which participants were asked to rank several models of an appliance control panel in order of perceived elegance using a one to 5 scale (1 most elegant, 5 least elegant) Expected effort was measured through an online survey (see survey) in which participants were asked to rank several models of an appliance control panel in order of perceived elegance using a one to 5 scale (the easiest to use) to 5 ( the hardest to use) Effective complexity is a metric described in the file Microwave EC.ppt. The EC value is computed based on the spatial organization of control elements on the panel (knobs, buttons, screens, etc.). Actual effort was measured through total execution time of the three tasks by every participant, including possible mistakes and subsequent new attempts. The Kruskal Wallis test and post hoc test are reported in the data actual effort folder
Regional heterogeneity in gene expression, regulation and coherence in hippocampus and prefrontal cortex across development and in schizophrenia. Collado-Torres et al, Neuron, 2019.
Contributors: Leonardo Collado-Torres, Emily E Burke, Amy Peterson, Joo Heon Shin, Richard Straub, Nina Rajpurohit, Stephen A Semick, William S Ulrich, BrainSeq Consortium, Amanda J Price
... This dataset contains the Supplementary Figures and Tables for the "Regional heterogeneity in gene expression, regulation and coherence in hippocampus and prefrontal cortex across development and in schizophrenia" article by Collado-Torres et al, Neuron, 2019. Please cite the original article as well as the data itself if appropriate. For clarifications about the figures or data, please contact us by creating an issue at https://github.com/LieberInstitute/brainseq_phase2/issues. Thank you!
Contributors: Ricardo Valls
... Golden Software Inc. included the method of cokriging in the newest version of SURFER 17. This has opened a new tool for interpreting geochemical data. We can use cokriging in SURFER 17 to improve the quality of maps and to predict similar targets in nearby areas. We use cokriging when we want to process data from different datasets. One dataset is always smaller than the other. Here, I first tasted the method with a hypothetical geochemical model combining a smaller dataset of FA gold results with a larger dataset of ICP-MS multi-elements. Later, I applied this method to real data from a soil sampling project in Mozambique. I tested a known mineralized target and also an extended area to predict gold targets. I also had the gold results for the extended area. They allowed me to confirm the effectiveness of cokriging in predicting the new targets. There are many opportunities where we can apply cokriging as a prediction tool. One situation is when an initial sampling returned a group of interesting but isolated gold results. We can then use a cheaper method, like ICP-MS, to better understand the gold distribution in the area.