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- ChIP-seq of H1 human embryonic stem cells (hESCs) to map the global binding profile of EZH2 to investigate the association of PRDM14 binding with the PRC2 in hESCsAn experiment was performed to map the global binding profile of EZH2 in human embryonic stem cells (hESCs). How the Polycomb Repressive Complex 2 (PRC2) is recruited to the DNA in hESC remains largely unknown. Previous studies on the transcription factor PRDM14 suggested that PRDM14 plays a repressive role in hESCs. Here, we mapped the global binding profile of EZH2 in hESC to investigate the association of PRDM14 binding with the PRC2 in hESCs. EZH2 binding is found to be enriched in PRDM14 binding sites. The PRC2 dependent repressive role of PRDM14 is further supported by the strong correlation of PRDM14 binding with the repressive histone modification H3K27me3.
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- CEL-Seq-pipeline: CEL-Seq2 pipeline version 1.0CEL-Seq2 pipeline version 1.0
- Software/Code
- Racist Activism in Chicago: 1977-1987Photographs by Chip Berlet
- Collection
- Trumping Democracy Test PageThis material is in a collection related to the book Trumping Democracy edited by Chip Berlet for Routledge
- Other
- Trumping Democracy: Berlet, Routledge 2019 - Online Resource GuideThis page is an online resource guide for the book Trumping Democracy: Chip Berlet, Routledge 2019.
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- CIVICUS-Berlet-2019-ResourcesCIVICUS Interview with Chip Berlet 2019
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- Trumping Democracy: Berlet, Routledge 2019 - Online Resource GuideThis page is an online resource guide for the book Trumping Democracy: Chip Berlet, Routledge 2019.
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- Racist Activism in Chicago: 1977-1987Photographs by Chip Berlet
- Collection
- Trumping Democracy: Online ResourcesThis page contains a downloadable online resource guide for the book Trumping Democracy: Chip Berlet, Routledge 2019.
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- Christian Dominionism, Christian Nationalism, and Christian TheocracyThe book Trumping Democracy: From Reagan to Alt-Right, is a collection edited by Chip Berlet published in 2019 by Routledge.
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