gene id gene name description GO_id GO_term KO_ID KO_Description kegg_id kegg_term locus g1 g2 log2FC Pvalue Qvalue updown ENSG00000172995 ARPP21 cAMP regulated phosphoprotein 21kDa [Source:HGNC Symbol;Acc:HGNC:16968] - - - - - - chr3:35680437-35835988 0.138132766 0.00642141 4.427021689 1.21E-10 1.05E-07 UP ENSG00000156049 GNA14 "guanine nucleotide binding protein (G protein), alpha 14 [Source:HGNC Symbol;Acc:HGNC:4382]" GO:0023052|GO:0005576|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0032991|GO:0005488|GO:0019898|GO:0005622|GO:0050794|GO:0051716|GO:0043167|GO:0006950|GO:0097159|GO:0071944|GO:0016787|GO:0097367|GO:0005886|GO:0005515|GO:0043234|GO:0043227|GO:0036094|GO:0016817|GO:0005834|GO:0005102|GO:0032403|GO:0019897|GO:0070062|GO:0001775|GO:0031234|GO:0009611|GO:0000166|GO:0043169|GO:0050878|GO:0031982|GO:0007165|GO:0007154|GO:0009898|GO:0001882|GO:0030168|GO:0042060|GO:0031683|GO:0032549|GO:0035639|GO:0017076|GO:0007186|GO:0046872|GO:0007599|GO:0001883|GO:0016818|GO:0001664|GO:0007596|GO:0005525|GO:0019001|GO:0007212|GO:0007187|GO:0007200|GO:0016462|GO:0060158|GO:0017111|GO:0007188|GO:0003924 "signaling|extracellular region|membrane|cell|response to stimulus|signal transducer activity|catalytic activity|organelle|cellular process|metabolic process|macromolecular complex|binding|extrinsic component of membrane|intracellular|regulation of cellular process|cellular response to stimulus|ion binding|response to stress|organic cyclic compound binding|cell periphery|hydrolase activity|carbohydrate derivative binding|plasma membrane|protein binding|protein complex|membrane-bounded organelle|small molecule binding|hydrolase activity, acting on acid anhydrides|heterotrimeric G-protein complex|receptor binding|protein complex binding|extrinsic component of plasma membrane|extracellular exosome|cell activation|extrinsic component of cytoplasmic side of plasma membrane|response to wounding|nucleotide binding|cation binding|regulation of body fluid levels|vesicle|signal transduction|cell communication|cytoplasmic side of plasma membrane|nucleoside binding|platelet activation|wound healing|G-protein beta/gamma-subunit complex binding|ribonucleoside binding|purine ribonucleoside triphosphate binding|purine nucleotide binding|G-protein coupled receptor signaling pathway|metal ion binding|hemostasis|purine nucleoside binding|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|G-protein coupled receptor binding|blood coagulation|GTP binding|guanyl nucleotide binding|dopamine receptor signaling pathway|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|phospholipase C-activating G-protein coupled receptor signaling pathway|pyrophosphatase activity|phospholipase C-activating dopamine receptor signaling pathway|nucleoside-triphosphatase activity|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|GTPase activity" K04636 guanine nucleotide-binding protein subunit alpha-14[-] hsa04020|hsa05142|hsa05146 Calcium signaling pathway - Homo sapiens (human)|Chagas disease (American trypanosomiasis) - Homo sapiens (human)|Amoebiasis - Homo sapiens (human) chr9:80037995-80263223 11.07401635 4.987589461 1.150763933 2.02E-10 1.58E-07 UP ENSG00000162006 MSLNL mesothelin-like [Source:HGNC Symbol;Acc:HGNC:14170] GO:0016020|GO:0031224|GO:0007155|GO:0016021 membrane|intrinsic component of membrane|cell adhesion|integral component of membrane - - - - chr16:819428-833370 6.976702422 2.301956899 1.599684478 2.76E-09 1.35E-06 UP ENSG00000243836 WDR86-AS1 WDR86 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:41186] - - - - - - chr7:151106247-151110440 2.193190159 0.661118227 1.730050711 4.59E-09 2.08E-06 UP ENSG00000164303 ENPP6 ectonucleotide pyrophosphatase/phosphodiesterase 6 [Source:HGNC Symbol;Acc:HGNC:23409] GO:0005576|GO:0016020|GO:0005623|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0031224|GO:0009056|GO:0044237|GO:0006807|GO:0071944|GO:0016787|GO:0005886|GO:0043227|GO:0071704|GO:0016788|GO:0031225|GO:0070062|GO:0034641|GO:0006629|GO:0044281|GO:0031982|GO:0042578|GO:0019695|GO:0016042|GO:0009308|GO:0006066|GO:0006576|GO:0008081|GO:0047390|GO:0008889 "extracellular region|membrane|cell|catalytic activity|organelle|cellular process|metabolic process|intrinsic component of membrane|catabolic process|cellular metabolic process|nitrogen compound metabolic process|cell periphery|hydrolase activity|plasma membrane|membrane-bounded organelle|organic substance metabolic process|hydrolase activity, acting on ester bonds|anchored component of membrane|extracellular exosome|cellular nitrogen compound metabolic process|lipid metabolic process|small molecule metabolic process|vesicle|phosphoric ester hydrolase activity|choline metabolic process|lipid catabolic process|amine metabolic process|alcohol metabolic process|cellular biogenic amine metabolic process|phosphoric diester hydrolase activity|glycerophosphocholine cholinephosphodiesterase activity|glycerophosphodiester phosphodiesterase activity" K08743 ectonucleotide pyrophosphatase/phosphodiesterase family member 6 [EC:3.1.4.-][-] hsa00565 Ether lipid metabolism - Homo sapiens (human) chr4:185009859-185142383 4.140803153 0.295863283 3.806908046 5.26E-09 2.34E-06 UP ENSG00000188660 LINC00319 long intergenic non-protein coding RNA 319 [Source:HGNC Symbol;Acc:HGNC:19730] - - - - - - chr21:44866481-44873773 1.974823397 0.73369206 1.428477066 5.68E-09 2.42E-06 UP ENSG00000112936 C7 complement component 7 [Source:HGNC Symbol;Acc:HGNC:1346] - - K03996 complement component 7[-] hsa05322|hsa04610|hsa05020 Systemic lupus erythematosus - Homo sapiens (human)|Complement and coagulation cascades - Homo sapiens (human)|Prion diseases - Homo sapiens (human) chr5:40909354-40983041 17.63792402 4.12755454 2.095321582 1.12E-08 4.02E-06 UP ENSG00000107518 ATRNL1 attractin like 1 [Source:HGNC Symbol;Acc:HGNC:29063] GO:0023052|GO:0016020|GO:0050896|GO:0009987|GO:0032502|GO:0005488|GO:0031224|GO:0048856|GO:0030246|GO:0050794|GO:0051716|GO:0005515|GO:0004872|GO:0007275|GO:0016021|GO:0007165|GO:0007154|GO:0007186 signaling|membrane|response to stimulus|cellular process|developmental process|binding|intrinsic component of membrane|anatomical structure development|carbohydrate binding|regulation of cellular process|cellular response to stimulus|protein binding|receptor activity|multicellular organism development|integral component of membrane|signal transduction|cell communication|G-protein coupled receptor signaling pathway - - - - chr10:116853130-117708503 0.304023634 0.077498558 1.971942113 1.28E-08 4.52E-06 UP ENSG00000170381 SEMA3E "sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E [Source:HGNC Symbol;Acc:HGNC:10727]" - - K06840 semaphorin 3[-] hsa04360 Axon guidance - Homo sapiens (human) chr7:82993222-83278326 9.908346231 3.635678449 1.446419673 4.75E-08 1.06E-05 UP ENSG00000105825 TFPI2 tissue factor pathway inhibitor 2 [Source:HGNC Symbol;Acc:HGNC:11761] GO:0005576|GO:0031012|GO:0005623|GO:0005198|GO:0050896|GO:0043226|GO:0009987|GO:0008152|GO:0005622|GO:0043229|GO:0044237|GO:0050794|GO:0006950|GO:0030234|GO:0005201|GO:0019222|GO:0009892|GO:0048523|GO:0043227|GO:0005578|GO:0071704|GO:0044092|GO:0043086|GO:0043231|GO:0009611|GO:0050790|GO:0019538|GO:0031324|GO:0050878|GO:0031323|GO:0004857|GO:0051248|GO:0032269|GO:0042060|GO:0005634|GO:0044267|GO:0030414|GO:0051346|GO:0006508|GO:0007599|GO:0051246|GO:0007596|GO:0032268|GO:0052547|GO:0030162|GO:0004866|GO:0010466|GO:0045861|GO:0004867|GO:0010951|GO:0052548 extracellular region|extracellular matrix|cell|structural molecule activity|response to stimulus|organelle|cellular process|metabolic process|intracellular|intracellular organelle|cellular metabolic process|regulation of cellular process|response to stress|enzyme regulator activity|extracellular matrix structural constituent|regulation of metabolic process|negative regulation of metabolic process|negative regulation of cellular process|membrane-bounded organelle|proteinaceous extracellular matrix|organic substance metabolic process|negative regulation of molecular function|negative regulation of catalytic activity|intracellular membrane-bounded organelle|response to wounding|regulation of catalytic activity|protein metabolic process|negative regulation of cellular metabolic process|regulation of body fluid levels|regulation of cellular metabolic process|enzyme inhibitor activity|negative regulation of protein metabolic process|negative regulation of cellular protein metabolic process|wound healing|nucleus|cellular protein metabolic process|peptidase inhibitor activity|negative regulation of hydrolase activity|proteolysis|hemostasis|regulation of protein metabolic process|blood coagulation|regulation of cellular protein metabolic process|regulation of peptidase activity|regulation of proteolysis|endopeptidase inhibitor activity|negative regulation of peptidase activity|negative regulation of proteolysis|serine-type endopeptidase inhibitor activity|negative regulation of endopeptidase activity|regulation of endopeptidase activity - - - - chr7:93514709-93520303 23.84808462 5.240900308 2.185986828 5.86E-08 1.20E-05 UP ENSG00000103257 SLC7A5 "solute carrier family 7 (amino acid transporter light chain, L system), member 5 [Source:HGNC Symbol;Acc:HGNC:11063]" GO:0005576|GO:0040011|GO:0016020|GO:0005623|GO:0050896|GO:0002376|GO:0005215|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0048870|GO:0031224|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0022857|GO:0006950|GO:0050900|GO:0006807|GO:0071944|GO:0005886|GO:0045177|GO:0003823|GO:0043227|GO:0071704|GO:0006520|GO:0042277|GO:0055085|GO:0022891|GO:0048731|GO:0005737|GO:0016477|GO:0006082|GO:0048869|GO:0007275|GO:0043231|GO:0070062|GO:0009611|GO:0006928|GO:0006810|GO:0016324|GO:0016021|GO:0050878|GO:0044281|GO:0042605|GO:0031982|GO:0005829|GO:0042060|GO:0005634|GO:0030154|GO:0015075|GO:0006811|GO:0007399|GO:0031981|GO:1903825|GO:0007599|GO:0034220|GO:0007596|GO:0005730|GO:0008509|GO:0046943|GO:0046942|GO:0006865|GO:0098656|GO:0006820|GO:0019752|GO:0015711|GO:0003333|GO:0015807|GO:0008514|GO:0015804|GO:0015171|GO:0015179|GO:0015175 extracellular region|locomotion|membrane|cell|response to stimulus|immune system process|transporter activity|organelle|cellular process|metabolic process|developmental process|binding|cell motility|intrinsic component of membrane|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|transmembrane transporter activity|response to stress|leukocyte migration|nitrogen compound metabolic process|cell periphery|plasma membrane|apical part of cell|antigen binding|membrane-bounded organelle|organic substance metabolic process|cellular amino acid metabolic process|peptide binding|transmembrane transport|substrate-specific transmembrane transporter activity|system development|cytoplasm|cell migration|organic acid metabolic process|cellular developmental process|multicellular organism development|intracellular membrane-bounded organelle|extracellular exosome|response to wounding|movement of cell or subcellular component|transport|apical plasma membrane|integral component of membrane|regulation of body fluid levels|small molecule metabolic process|peptide antigen binding|vesicle|cytosol|wound healing|nucleus|cell differentiation|ion transmembrane transporter activity|ion transport|nervous system development|nuclear lumen|organic acid transmembrane transport|hemostasis|ion transmembrane transport|blood coagulation|nucleolus|anion transmembrane transporter activity|carboxylic acid transmembrane transporter activity|carboxylic acid transport|amino acid transport|anion transmembrane transport|anion transport|carboxylic acid metabolic process|organic anion transport|amino acid transmembrane transport|L-amino acid transport|organic anion transmembrane transporter activity|neutral amino acid transport|amino acid transmembrane transporter activity|L-amino acid transmembrane transporter activity|neutral amino acid transmembrane transporter activity K13780 "solute carrier family 7 (L-type amino acid transporter), member 5[-]" hsa05230 Central carbon metabolism in cancer - Homo sapiens (human) chr16:87863629-87903094 31.65562315 11.94036052 1.406615399 8.42E-08 1.61E-05 UP ENSG00000146192 FGD2 "FYVE, RhoGEF and PH domain containing 2 [Source:HGNC Symbol;Acc:HGNC:3664]" - - - - - - chr6:36973423-36996846 18.41942211 7.511118219 1.294128189 9.79E-08 1.86E-05 UP ENSG00000261327 RP11-863P13.7 - - - - - - - chr16:88210904-88219696 0.539521924 0.111256376 2.277793566 9.87E-08 1.86E-05 UP ENSG00000117322 CR2 complement component (3d/Epstein Barr virus) receptor 2 [Source:HGNC Symbol;Acc:HGNC:2336] GO:0023052|GO:0005576|GO:0016020|GO:0005623|GO:0050896|GO:0002376|GO:0004871|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0032991|GO:0005488|GO:0002684|GO:0038023|GO:0008283|GO:0031224|GO:0006955|GO:0048856|GO:0002520|GO:0050794|GO:0051716|GO:0006950|GO:0097159|GO:0071944|GO:0005886|GO:0005515|GO:0009986|GO:0045321|GO:0043234|GO:0043227|GO:0002682|GO:0004872|GO:0071704|GO:0002253|GO:0045087|GO:0006952|GO:0043235|GO:0004888|GO:0050776|GO:0046649|GO:0048731|GO:0006959|GO:0048869|GO:0002250|GO:0007275|GO:0070062|GO:0046983|GO:0001775|GO:0042802|GO:0006956|GO:0016021|GO:0001848|GO:0019538|GO:0003676|GO:0050778|GO:0070661|GO:0031982|GO:0048513|GO:0007165|GO:0007154|GO:0002443|GO:0009897|GO:0030097|GO:0046651|GO:0042113|GO:0030098|GO:0030154|GO:0002460|GO:0003677|GO:0004875|GO:0042803|GO:0002455|GO:0032943|GO:0007166|GO:0002764|GO:0006958|GO:0002768|GO:0002521|GO:0030183|GO:0042100|GO:0002430|GO:0019724|GO:0016064 "signaling|extracellular region|membrane|cell|response to stimulus|immune system process|signal transducer activity|organelle|cellular process|metabolic process|developmental process|macromolecular complex|binding|positive regulation of immune system process|signaling receptor activity|cell proliferation|intrinsic component of membrane|immune response|anatomical structure development|immune system development|regulation of cellular process|cellular response to stimulus|response to stress|organic cyclic compound binding|cell periphery|plasma membrane|protein binding|cell surface|leukocyte activation|protein complex|membrane-bounded organelle|regulation of immune system process|receptor activity|organic substance metabolic process|activation of immune response|innate immune response|defense response|receptor complex|transmembrane signaling receptor activity|regulation of immune response|lymphocyte activation|system development|humoral immune response|cellular developmental process|adaptive immune response|multicellular organism development|extracellular exosome|protein dimerization activity|cell activation|identical protein binding|complement activation|integral component of membrane|complement binding|protein metabolic process|nucleic acid binding|positive regulation of immune response|leukocyte proliferation|vesicle|animal organ development|signal transduction|cell communication|leukocyte mediated immunity|external side of plasma membrane|hemopoiesis|lymphocyte proliferation|B cell activation|lymphocyte differentiation|cell differentiation|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains|DNA binding|complement receptor activity|protein homodimerization activity|humoral immune response mediated by circulating immunoglobulin|mononuclear cell proliferation|cell surface receptor signaling pathway|immune response-regulating signaling pathway|complement activation, classical pathway|immune response-regulating cell surface receptor signaling pathway|leukocyte differentiation|B cell differentiation|B cell proliferation|complement receptor mediated signaling pathway|B cell mediated immunity|immunoglobulin mediated immune response" K04012 complement receptor type 2[-] hsa05169|hsa04640|hsa04610|hsa04662 Epstein-Barr virus infection - Homo sapiens (human)|Hematopoietic cell lineage - Homo sapiens (human)|Complement and coagulation cascades - Homo sapiens (human)|B cell receptor signaling pathway - Homo sapiens (human) chr1:207627575-207663240 1.175708848 0.162007296 2.859400143 1.10E-07 2.01E-05 UP ENSG00000156076 WIF1 WNT inhibitory factor 1 [Source:HGNC Symbol;Acc:HGNC:18081] GO:0023052|GO:0005576|GO:0050896|GO:0009987|GO:0032502|GO:0005488|GO:0023057|GO:0048856|GO:0050794|GO:0051716|GO:0005515|GO:0050793|GO:0048523|GO:0045597|GO:0045595|GO:0009968|GO:0048869|GO:0007275|GO:0009966|GO:0007165|GO:0010646|GO:0007154|GO:0045600|GO:0030154|GO:0045598|GO:0030178|GO:0007166|GO:0030111|GO:0060828|GO:0090090|GO:0016055|GO:0045444|GO:0060070 signaling|extracellular region|response to stimulus|cellular process|developmental process|binding|negative regulation of signaling|anatomical structure development|regulation of cellular process|cellular response to stimulus|protein binding|regulation of developmental process|negative regulation of cellular process|positive regulation of cell differentiation|regulation of cell differentiation|negative regulation of signal transduction|cellular developmental process|multicellular organism development|regulation of signal transduction|signal transduction|regulation of cell communication|cell communication|positive regulation of fat cell differentiation|cell differentiation|regulation of fat cell differentiation|negative regulation of Wnt signaling pathway|cell surface receptor signaling pathway|regulation of Wnt signaling pathway|regulation of canonical Wnt signaling pathway|negative regulation of canonical Wnt signaling pathway|Wnt signaling pathway|fat cell differentiation|canonical Wnt signaling pathway K01691 WNT inhibitory factor 1[-] hsa04310 Wnt signaling pathway - Homo sapiens (human) chr12:65444406-65515346 9.969479636 1.278385505 2.963195248 1.31E-07 2.32E-05 UP ENSG00000164093 PITX2 paired-like homeodomain 2 [Source:HGNC Symbol;Acc:HGNC:9005] - - K04686 paired-like homeodomain transcription factor 2[-] hsa04350 TGF-beta signaling pathway - Homo sapiens (human) chr4:111538579-111563279 1.103316922 0.238376581 2.210532847 1.58E-07 2.70E-05 UP ENSG00000169885 CALML6 calmodulin like 6 [Source:HGNC Symbol;Acc:HGNC:24193] - - K02183 calmodulin[-] hsa04740|hsa04014|hsa04015|hsa04024|hsa04020|hsa05034|hsa05152|hsa05010|hsa04022|hsa04921|hsa04261|hsa04910|hsa04728|hsa04114|hsa04722|hsa04270|hsa04922|hsa04916|hsa04915|hsa04750|hsa04070|hsa04713|hsa04912|hsa04970|hsa04925|hsa05133|hsa04971|hsa05031|hsa04720|hsa05214|hsa04924|hsa04744 Olfactory transduction - Homo sapiens (human)|Ras signaling pathway - Homo sapiens (human)|Rap1 signaling pathway - Homo sapiens (human)|cAMP signaling pathway - Homo sapiens (human)|Calcium signaling pathway - Homo sapiens (human)|Alcoholism - Homo sapiens (human)|Tuberculosis - Homo sapiens (human)|Alzheimer's disease - Homo sapiens (human)|cGMP-PKG signaling pathway - Homo sapiens (human)|Oxytocin signaling pathway - Homo sapiens (human)|Adrenergic signaling in cardiomyocytes - Homo sapiens (human)|Insulin signaling pathway - Homo sapiens (human)|Dopaminergic synapse - Homo sapiens (human)|Oocyte meiosis - Homo sapiens (human)|Neurotrophin signaling pathway - Homo sapiens (human)|Vascular smooth muscle contraction - Homo sapiens (human)|Glucagon signaling pathway - Homo sapiens (human)|Melanogenesis - Homo sapiens (human)|Estrogen signaling pathway - Homo sapiens (human)|Inflammatory mediator regulation of TRP channels - Homo sapiens (human)|Phosphatidylinositol signaling system - Homo sapiens (human)|Circadian entrainment - Homo sapiens (human)|GnRH signaling pathway - Homo sapiens (human)|Salivary secretion - Homo sapiens (human)|Aldosterone synthesis and secretion - Homo sapiens (human)|Pertussis - Homo sapiens (human)|Gastric acid secretion - Homo sapiens (human)|Amphetamine addiction - Homo sapiens (human)|Long-term potentiation - Homo sapiens (human)|Glioma - Homo sapiens (human)|Renin secretion - Homo sapiens (human)|Phototransduction - Homo sapiens (human) chr1:1846266-1848733 3.597870549 1.482234593 1.279369479 2.37E-07 3.76E-05 UP ENSG00000198959 TGM2 transglutaminase 2 [Source:HGNC Symbol;Acc:HGNC:11778] GO:0023052|GO:0005576|GO:0016020|GO:0005623|GO:0030054|GO:0050896|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0031224|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0050794|GO:0051716|GO:0043167|GO:0007155|GO:0048646|GO:0071944|GO:0005886|GO:0005515|GO:0009653|GO:0016740|GO:0043227|GO:0030055|GO:0071704|GO:0042592|GO:0005912|GO:0009888|GO:0035295|GO:0048731|GO:0005737|GO:0019725|GO:0035148|GO:0016746|GO:0030155|GO:0005924|GO:0031226|GO:0035239|GO:0007275|GO:0043231|GO:0070062|GO:0006810|GO:0010942|GO:0008219|GO:0019538|GO:0001763|GO:0043169|GO:0009887|GO:0048729|GO:0045785|GO:0031982|GO:0048513|GO:0007165|GO:0007154|GO:0010941|GO:0048732|GO:0043068|GO:0005829|GO:0022612|GO:0016192|GO:0061138|GO:0060429|GO:0044267|GO:0007186|GO:0043067|GO:0043412|GO:0046872|GO:0005739|GO:0048878|GO:0005925|GO:0007431|GO:0012501|GO:0006909|GO:0055082|GO:0002009|GO:0006873|GO:0060445|GO:0006464|GO:0003810|GO:0007435|GO:0060662|GO:0006897|GO:0050801|GO:0043065|GO:0006915|GO:0042981|GO:0043277|GO:0007200|GO:0018149|GO:0030003|GO:0055065|GO:0006875|GO:0055074|GO:0006874|GO:0032469|GO:0051560|GO:0032471|GO:0051561 "signaling|extracellular region|membrane|cell|cell junction|response to stimulus|catalytic activity|organelle|cellular process|metabolic process|developmental process|binding|intrinsic component of membrane|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|regulation of cellular process|cellular response to stimulus|ion binding|cell adhesion|anatomical structure formation involved in morphogenesis|cell periphery|plasma membrane|protein binding|anatomical structure morphogenesis|transferase activity|membrane-bounded organelle|cell-substrate junction|organic substance metabolic process|homeostatic process|adherens junction|tissue development|tube development|system development|cytoplasm|cellular homeostasis|tube formation|transferase activity, transferring acyl groups|regulation of cell adhesion|cell-substrate adherens junction|intrinsic component of plasma membrane|tube morphogenesis|multicellular organism development|intracellular membrane-bounded organelle|extracellular exosome|transport|positive regulation of cell death|cell death|protein metabolic process|morphogenesis of a branching structure|cation binding|organ morphogenesis|tissue morphogenesis|positive regulation of cell adhesion|vesicle|animal organ development|signal transduction|cell communication|regulation of cell death|gland development|positive regulation of programmed cell death|cytosol|gland morphogenesis|vesicle-mediated transport|morphogenesis of a branching epithelium|epithelium development|cellular protein metabolic process|G-protein coupled receptor signaling pathway|regulation of programmed cell death|macromolecule modification|metal ion binding|mitochondrion|chemical homeostasis|focal adhesion|salivary gland development|programmed cell death|phagocytosis|cellular chemical homeostasis|morphogenesis of an epithelium|cellular ion homeostasis|branching involved in salivary gland morphogenesis|cellular protein modification process|protein-glutamine gamma-glutamyltransferase activity|salivary gland morphogenesis|salivary gland cavitation|endocytosis|ion homeostasis|positive regulation of apoptotic process|apoptotic process|regulation of apoptotic process|apoptotic cell clearance|phospholipase C-activating G-protein coupled receptor signaling pathway|peptide cross-linking|cellular cation homeostasis|metal ion homeostasis|cellular metal ion homeostasis|calcium ion homeostasis|cellular calcium ion homeostasis|endoplasmic reticulum calcium ion homeostasis|mitochondrial calcium ion homeostasis|negative regulation of endoplasmic reticulum calcium ion concentration|positive regulation of mitochondrial calcium ion concentration" K05625 transglutaminase 2[2.3.2.13] hsa05016 Huntington's disease - Homo sapiens (human) chr20:36756863-36794980 204.8104247 96.29852681 1.088703516 3.78E-07 5.39E-05 UP ENSG00000103269 RHBDL1 "rhomboid, veinlet-like 1 (Drosophila) [Source:HGNC Symbol;Acc:HGNC:10007]" GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0003824|GO:0009987|GO:0008152|GO:0031224|GO:0050794|GO:0051716|GO:0071944|GO:0016787|GO:0005886|GO:0071704|GO:0008233|GO:0031226|GO:0017171|GO:0016021|GO:0005887|GO:0019538|GO:0007165|GO:0007154|GO:0008236|GO:0006508|GO:0004252|GO:0004175 signaling|membrane|cell|response to stimulus|catalytic activity|cellular process|metabolic process|intrinsic component of membrane|regulation of cellular process|cellular response to stimulus|cell periphery|hydrolase activity|plasma membrane|organic substance metabolic process|peptidase activity|intrinsic component of plasma membrane|serine hydrolase activity|integral component of membrane|integral component of plasma membrane|protein metabolic process|signal transduction|cell communication|serine-type peptidase activity|proteolysis|serine-type endopeptidase activity|endopeptidase activity - - - - chr16:725666-728268 6.630957173 3.093016604 1.100202559 8.06E-07 0.000101 UP ENSG00000124159 MATN4 matrilin 4 [Source:HGNC Symbol;Acc:HGNC:6910] GO:0005576|GO:0050896|GO:0009987|GO:0005488|GO:0016043|GO:0043167|GO:0006950|GO:0005515|GO:0043062|GO:0009611|GO:0043169|GO:0048678|GO:0030198|GO:0046872|GO:0005509 extracellular region|response to stimulus|cellular process|binding|cellular component organization|ion binding|response to stress|protein binding|extracellular structure organization|response to wounding|cation binding|response to axon injury|extracellular matrix organization|metal ion binding|calcium ion binding - - - - chr20:43922085-43937169 2.815190935 0.514096939 2.453120445 9.06E-07 0.000111852 UP ENSG00000164530 PI16 peptidase inhibitor 16 [Source:HGNC Symbol;Acc:HGNC:21245] GO:0005576|GO:0016020|GO:0050896|GO:0040007|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0040008|GO:0031224|GO:0048589|GO:0048856|GO:0044237|GO:0016043|GO:0045926|GO:0050794|GO:0030234|GO:0019222|GO:0050793|GO:0009892|GO:0048523|GO:0016049|GO:0005615|GO:0043227|GO:0071704|GO:0051128|GO:0048638|GO:0044092|GO:0048588|GO:0045596|GO:0048468|GO:0046621|GO:0003012|GO:0009888|GO:0055017|GO:0014741|GO:0048731|GO:0043086|GO:0045595|GO:0046620|GO:0048869|GO:0007275|GO:0070062|GO:0050790|GO:0016021|GO:0061061|GO:0019538|GO:0007507|GO:0048635|GO:0031324|GO:0048640|GO:0031323|GO:0031982|GO:0004857|GO:0048513|GO:0001558|GO:0035265|GO:0030308|GO:0051248|GO:0010611|GO:0032269|GO:0060420|GO:0016202|GO:0045843|GO:0030154|GO:0055001|GO:0051147|GO:0010614|GO:0044267|GO:0035051|GO:0042692|GO:0030414|GO:0072358|GO:0051346|GO:0014896|GO:0007517|GO:0061050|GO:0051148|GO:0006508|GO:0051246|GO:0048738|GO:0061049|GO:0072359|GO:0060419|GO:0010721|GO:0061052|GO:0032268|GO:0051146|GO:0051153|GO:0052547|GO:0051154|GO:0055013|GO:0030162|GO:0055024|GO:0055026|GO:0055002|GO:0014706|GO:0010466|GO:0055007|GO:0045861|GO:0003300|GO:2000726 extracellular region|membrane|response to stimulus|growth|organelle|cellular process|metabolic process|developmental process|regulation of growth|intrinsic component of membrane|developmental growth|anatomical structure development|cellular metabolic process|cellular component organization|negative regulation of growth|regulation of cellular process|enzyme regulator activity|regulation of metabolic process|regulation of developmental process|negative regulation of metabolic process|negative regulation of cellular process|cell growth|extracellular space|membrane-bounded organelle|organic substance metabolic process|regulation of cellular component organization|regulation of developmental growth|negative regulation of molecular function|developmental cell growth|negative regulation of cell differentiation|cell development|negative regulation of organ growth|muscle system process|tissue development|cardiac muscle tissue growth|negative regulation of muscle hypertrophy|system development|negative regulation of catalytic activity|regulation of cell differentiation|regulation of organ growth|cellular developmental process|multicellular organism development|extracellular exosome|regulation of catalytic activity|integral component of membrane|muscle structure development|protein metabolic process|heart development|negative regulation of muscle organ development|negative regulation of cellular metabolic process|negative regulation of developmental growth|regulation of cellular metabolic process|vesicle|enzyme inhibitor activity|animal organ development|regulation of cell growth|organ growth|negative regulation of cell growth|negative regulation of protein metabolic process|regulation of cardiac muscle hypertrophy|negative regulation of cellular protein metabolic process|regulation of heart growth|regulation of striated muscle tissue development|negative regulation of striated muscle tissue development|cell differentiation|muscle cell development|regulation of muscle cell differentiation|negative regulation of cardiac muscle hypertrophy|cellular protein metabolic process|cardiocyte differentiation|muscle cell differentiation|peptidase inhibitor activity|cardiovascular system development|negative regulation of hydrolase activity|muscle hypertrophy|muscle organ development|regulation of cell growth involved in cardiac muscle cell development|negative regulation of muscle cell differentiation|proteolysis|regulation of protein metabolic process|cardiac muscle tissue development|cell growth involved in cardiac muscle cell development|circulatory system development|heart growth|negative regulation of cell development|negative regulation of cell growth involved in cardiac muscle cell development|regulation of cellular protein metabolic process|striated muscle cell differentiation|regulation of striated muscle cell differentiation|regulation of peptidase activity|negative regulation of striated muscle cell differentiation|cardiac muscle cell development|regulation of proteolysis|regulation of cardiac muscle tissue development|negative regulation of cardiac muscle tissue development|striated muscle cell development|striated muscle tissue development|negative regulation of peptidase activity|cardiac muscle cell differentiation|negative regulation of proteolysis|cardiac muscle hypertrophy|negative regulation of cardiac muscle cell differentiation - - - - chr6:36922209-36932613 94.21510577 22.12497655 2.090282463 1.29E-06 0.000150113 UP ENSG00000171811 TTC40 cilia and flagella associated protein 46 [Source:HGNC Symbol;Acc:HGNC:25247] GO:0005623|GO:0043226|GO:0009987|GO:0032502|GO:0005622|GO:0043229|GO:0048856|GO:0016043|GO:0005929|GO:0042995|GO:0048646|GO:0009653|GO:0030030|GO:0005737|GO:0048869|GO:0022607|GO:0007017|GO:0005930|GO:0006996|GO:0007010|GO:0042384|GO:0000902|GO:0032990|GO:0048858|GO:0030031|GO:0044782|GO:0070925|GO:0000226|GO:0035082|GO:0005856|GO:0001578|GO:0060271 cell|organelle|cellular process|developmental process|intracellular|intracellular organelle|anatomical structure development|cellular component organization|cilium|cell projection|anatomical structure formation involved in morphogenesis|anatomical structure morphogenesis|cell projection organization|cytoplasm|cellular developmental process|cellular component assembly|microtubule-based process|axoneme|organelle organization|cytoskeleton organization|cilium assembly|cell morphogenesis|cell part morphogenesis|cell projection morphogenesis|cell projection assembly|cilium organization|organelle assembly|microtubule cytoskeleton organization|axoneme assembly|cytoskeleton|microtubule bundle formation|cilium morphogenesis - - - - chr10:134621896-134756327 3.667241657 1.623009205 1.176024155 1.60E-06 0.000175392 UP ENSG00000142319 SLC6A3 "solute carrier family 6 (neurotransmitter transporter), member 3 [Source:HGNC Symbol;Acc:HGNC:11049]" GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0005215|GO:0007610|GO:0040007|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0045927|GO:0040008|GO:0031224|GO:0009056|GO:0005622|GO:0048589|GO:0048856|GO:0044237|GO:0022857|GO:0050794|GO:0009058|GO:0009605|GO:0043167|GO:0042995|GO:0006807|GO:0097159|GO:0007626|GO:0071944|GO:0005886|GO:0005326|GO:0005515|GO:0019222|GO:0050793|GO:0044297|GO:0071704|GO:0010033|GO:0010243|GO:0048638|GO:0055085|GO:0007420|GO:0047485|GO:0007267|GO:0022891|GO:0048731|GO:0043005|GO:1901360|GO:0005328|GO:0005737|GO:0044249|GO:0031226|GO:0021536|GO:0007275|GO:0034641|GO:0001505|GO:0048639|GO:0006810|GO:0006725|GO:0016021|GO:0030900|GO:0005887|GO:0042133|GO:0035264|GO:0043169|GO:0036477|GO:0001964|GO:0050878|GO:0040014|GO:0031323|GO:0050877|GO:0048513|GO:0021984|GO:0043025|GO:0007154|GO:0040018|GO:0060322|GO:0048732|GO:0042136|GO:0006584|GO:0018958|GO:0060134|GO:0007595|GO:0046903|GO:0007417|GO:0030879|GO:0035240|GO:0050905|GO:0015075|GO:0042417|GO:0006811|GO:0021983|GO:0005329|GO:0006836|GO:0060359|GO:0007399|GO:0007589|GO:0014070|GO:0019439|GO:0015844|GO:0009308|GO:0034220|GO:0007600|GO:0030424|GO:0008504|GO:0043279|GO:0042220|GO:0042053|GO:0009712|GO:0042420|GO:0015293|GO:0042423|GO:0008324|GO:0042416|GO:0006812|GO:0098655|GO:0015696|GO:0007606|GO:0072488|GO:0015672|GO:0007268|GO:0007608|GO:0015872|GO:0022890|GO:0046873|GO:0008519|GO:0015081 signaling|membrane|cell|response to stimulus|transporter activity|behavior|growth|cellular process|metabolic process|developmental process|binding|positive regulation of growth|regulation of growth|intrinsic component of membrane|catabolic process|intracellular|developmental growth|anatomical structure development|cellular metabolic process|transmembrane transporter activity|regulation of cellular process|biosynthetic process|response to external stimulus|ion binding|cell projection|nitrogen compound metabolic process|organic cyclic compound binding|locomotory behavior|cell periphery|plasma membrane|neurotransmitter transporter activity|protein binding|regulation of metabolic process|regulation of developmental process|cell body|organic substance metabolic process|response to organic substance|response to organonitrogen compound|regulation of developmental growth|transmembrane transport|brain development|protein N-terminus binding|cell-cell signaling|substrate-specific transmembrane transporter activity|system development|neuron projection|organic cyclic compound metabolic process|neurotransmitter:sodium symporter activity|cytoplasm|cellular biosynthetic process|intrinsic component of plasma membrane|diencephalon development|multicellular organism development|cellular nitrogen compound metabolic process|regulation of neurotransmitter levels|positive regulation of developmental growth|transport|cellular aromatic compound metabolic process|integral component of membrane|forebrain development|integral component of plasma membrane|neurotransmitter metabolic process|multicellular organism growth|cation binding|somatodendritic compartment|startle response|regulation of body fluid levels|regulation of multicellular organism growth|regulation of cellular metabolic process|neurological system process|animal organ development|adenohypophysis development|neuronal cell body|cell communication|positive regulation of multicellular organism growth|head development|gland development|neurotransmitter biosynthetic process|catecholamine metabolic process|phenol-containing compound metabolic process|prepulse inhibition|lactation|secretion|central nervous system development|mammary gland development|dopamine binding|neuromuscular process|ion transmembrane transporter activity|dopamine metabolic process|ion transport|pituitary gland development|dopamine transmembrane transporter activity|neurotransmitter transport|response to ammonium ion|nervous system development|body fluid secretion|response to organic cyclic compound|aromatic compound catabolic process|monoamine transport|amine metabolic process|ion transmembrane transport|sensory perception|axon|monoamine transmembrane transporter activity|response to alkaloid|response to cocaine|regulation of dopamine metabolic process|catechol-containing compound metabolic process|dopamine catabolic process|symporter activity|catecholamine biosynthetic process|cation transmembrane transporter activity|dopamine biosynthetic process|cation transport|cation transmembrane transport|ammonium transport|sensory perception of chemical stimulus|ammonium transmembrane transport|monovalent inorganic cation transport|synaptic transmission|sensory perception of smell|dopamine transport|inorganic cation transmembrane transporter activity|metal ion transmembrane transporter activity|ammonium transmembrane transporter activity|sodium ion transmembrane transporter activity - - - - chr5:1392909-1445545 0.140136736 0.032651037 2.10163447 2.31E-06 0.000233154 UP ENSG00000224549 RP11-370B11.3 - - - - - - - chr9:22767174-22768315 1.647021702 0.417776898 1.979054943 2.59E-06 0.000252223 UP ENSG00000169676 DRD5 dopamine receptor D5 [Source:HGNC Symbol;Acc:HGNC:3026] GO:0023052|GO:0022414|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0000003|GO:0007610|GO:0009987|GO:0008152|GO:0005488|GO:0009893|GO:0023057|GO:0038023|GO:0031224|GO:0044237|GO:0048609|GO:0050794|GO:0009058|GO:0051716|GO:0043167|GO:0042995|GO:0006950|GO:0006807|GO:0032504|GO:0097159|GO:0071944|GO:0005886|GO:0044708|GO:0019953|GO:0019222|GO:0009892|GO:0048523|GO:0004872|GO:0071704|GO:0010033|GO:0010243|GO:0042592|GO:0004888|GO:0044092|GO:0030594|GO:0007267|GO:0043086|GO:0050804|GO:1901360|GO:0072593|GO:0019725|GO:0044249|GO:0031226|GO:0003013|GO:0006139|GO:0043085|GO:0007618|GO:0031253|GO:0008217|GO:0034641|GO:0050803|GO:0009611|GO:0050790|GO:0006725|GO:0016021|GO:0005887|GO:0055086|GO:0031325|GO:0007611|GO:0005903|GO:0019637|GO:0045924|GO:0043169|GO:0046483|GO:0044281|GO:0031323|GO:0050877|GO:0007165|GO:0010646|GO:0007154|GO:0050805|GO:0050890|GO:0042060|GO:0031328|GO:0019693|GO:0031526|GO:0045777|GO:0048167|GO:0035240|GO:0060292|GO:0035150|GO:0003073|GO:0014075|GO:0019226|GO:0031281|GO:0071417|GO:0060359|GO:0007612|GO:0051174|GO:0007617|GO:0031279|GO:0007186|GO:0014070|GO:0051354|GO:0051349|GO:1901137|GO:0071867|GO:0007600|GO:0008015|GO:0006796|GO:0048878|GO:0004930|GO:0043279|GO:0042220|GO:0045776|GO:0055082|GO:0071869|GO:0071310|GO:0006163|GO:0008306|GO:0006873|GO:0009117|GO:0071407|GO:0009259|GO:0071870|GO:0009165|GO:0001992|GO:0008227|GO:0060180|GO:0046390|GO:0050801|GO:0033860|GO:0050880|GO:0004952|GO:0033861|GO:0007212|GO:0001975|GO:0046958|GO:0045761|GO:0007187|GO:0007200|GO:0045762|GO:0007606|GO:0009187|GO:0060158|GO:0007190|GO:0010578|GO:0007268|GO:0001993|GO:0006164|GO:0042310|GO:0001994|GO:0009190|GO:0046960|GO:0030003|GO:0030801|GO:0007191|GO:0007188|GO:0010579|GO:0001588|GO:0030816|GO:0007189|GO:0030814|GO:0009152|GO:0046058|GO:0055065|GO:0030817|GO:0030819|GO:0006875|GO:0007270|GO:0006171|GO:0055074|GO:0006874|GO:0001963 "signaling|reproductive process|membrane|cell|response to stimulus|signal transducer activity|reproduction|behavior|cellular process|metabolic process|binding|positive regulation of metabolic process|negative regulation of signaling|signaling receptor activity|intrinsic component of membrane|cellular metabolic process|multicellular organismal reproductive process|regulation of cellular process|biosynthetic process|cellular response to stimulus|ion binding|cell projection|response to stress|nitrogen compound metabolic process|multicellular organism reproduction|organic cyclic compound binding|cell periphery|plasma membrane|single-organism behavior|sexual reproduction|regulation of metabolic process|negative regulation of metabolic process|negative regulation of cellular process|receptor activity|organic substance metabolic process|response to organic substance|response to organonitrogen compound|homeostatic process|transmembrane signaling receptor activity|negative regulation of molecular function|neurotransmitter receptor activity|cell-cell signaling|negative regulation of catalytic activity|modulation of synaptic transmission|organic cyclic compound metabolic process|reactive oxygen species metabolic process|cellular homeostasis|cellular biosynthetic process|intrinsic component of plasma membrane|circulatory system process|nucleobase-containing compound metabolic process|positive regulation of catalytic activity|mating|cell projection membrane|regulation of blood pressure|cellular nitrogen compound metabolic process|regulation of synapse structure or activity|response to wounding|regulation of catalytic activity|cellular aromatic compound metabolic process|integral component of membrane|integral component of plasma membrane|nucleobase-containing small molecule metabolic process|positive regulation of cellular metabolic process|learning or memory|brush border|organophosphate metabolic process|regulation of female receptivity|cation binding|heterocycle metabolic process|small molecule metabolic process|regulation of cellular metabolic process|neurological system process|signal transduction|regulation of cell communication|cell communication|negative regulation of synaptic transmission|cognition|wound healing|positive regulation of cellular biosynthetic process|ribose phosphate metabolic process|brush border membrane|positive regulation of blood pressure|regulation of synaptic plasticity|dopamine binding|long term synaptic depression|regulation of tube size|regulation of systemic arterial blood pressure|response to amine|transmission of nerve impulse|positive regulation of cyclase activity|cellular response to organonitrogen compound|response to ammonium ion|learning|regulation of phosphorus metabolic process|mating behavior|regulation of cyclase activity|G-protein coupled receptor signaling pathway|response to organic cyclic compound|negative regulation of oxidoreductase activity|positive regulation of lyase activity|carbohydrate derivative biosynthetic process|response to monoamine|sensory perception|blood circulation|phosphate-containing compound metabolic process|chemical homeostasis|G-protein coupled receptor activity|response to alkaloid|response to cocaine|negative regulation of blood pressure|cellular chemical homeostasis|response to catecholamine|cellular response to organic substance|purine nucleotide metabolic process|associative learning|cellular ion homeostasis|nucleotide metabolic process|cellular response to organic cyclic compound|ribonucleotide metabolic process|cellular response to catecholamine stimulus|nucleotide biosynthetic process|regulation of systemic arterial blood pressure by vasopressin|G-protein coupled amine receptor activity|female mating behavior|ribose phosphate biosynthetic process|ion homeostasis|regulation of NAD(P)H oxidase activity|regulation of blood vessel size|dopamine neurotransmitter receptor activity|negative regulation of NAD(P)H oxidase activity|dopamine receptor signaling pathway|response to amphetamine|nonassociative learning|regulation of adenylate cyclase activity|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|phospholipase C-activating G-protein coupled receptor signaling pathway|positive regulation of adenylate cyclase activity|sensory perception of chemical stimulus|cyclic nucleotide metabolic process|phospholipase C-activating dopamine receptor signaling pathway|activation of adenylate cyclase activity|regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|synaptic transmission|regulation of systemic arterial blood pressure by norepinephrine-epinephrine|purine nucleotide biosynthetic process|vasoconstriction|norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure|cyclic nucleotide biosynthetic process|sensitization|cellular cation homeostasis|positive regulation of cyclic nucleotide metabolic process|adenylate cyclase-activating dopamine receptor signaling pathway|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway|dopamine neurotransmitter receptor activity, coupled via Gs|positive regulation of cAMP metabolic process|adenylate cyclase-activating G-protein coupled receptor signaling pathway|regulation of cAMP metabolic process|purine ribonucleotide biosynthetic process|cAMP metabolic process|metal ion homeostasis|regulation of cAMP biosynthetic process|positive regulation of cAMP biosynthetic process|cellular metal ion homeostasis|neuron-neuron synaptic transmission|cAMP biosynthetic process|calcium ion homeostasis|cellular calcium ion homeostasis|synaptic transmission, dopaminergic" K05840 dopamine receptor D5[-] hsa04080|hsa04024|hsa04020|hsa04728 Neuroactive ligand-receptor interaction - Homo sapiens (human)|cAMP signaling pathway - Homo sapiens (human)|Calcium signaling pathway - Homo sapiens (human)|Dopaminergic synapse - Homo sapiens (human) chr4:9783258-9785632 1.2504092 0.324956152 1.944083331 2.70E-06 0.000258887 UP ENSG00000223975 AP001048.4 - - - - - - - chr21:44885189-44887178 1.321510979 0.264140977 2.322808376 2.95E-06 0.000277875 UP ENSG00000009950 MLXIPL MLX interacting protein-like [Source:HGNC Symbol;Acc:HGNC:12744] GO:0001071|GO:0023052|GO:0005623|GO:0050896|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0032991|GO:0005488|GO:0009893|GO:0008283|GO:0009056|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0050794|GO:0009058|GO:0051716|GO:0003700|GO:0006807|GO:0097159|GO:0005515|GO:0009653|GO:0019222|GO:0009892|GO:0048523|GO:0043234|GO:0043227|GO:0071704|GO:0010033|GO:0042592|GO:0005667|GO:2000505|GO:0000981|GO:1901360|GO:0005737|GO:0019725|GO:0055114|GO:0044249|GO:0006139|GO:0006082|GO:0043231|GO:0034641|GO:0046983|GO:0051186|GO:0006091|GO:0008134|GO:0006725|GO:0009890|GO:0055086|GO:0031325|GO:0006629|GO:0019538|GO:0031324|GO:0019637|GO:0042127|GO:0045786|GO:0003676|GO:0046483|GO:0008284|GO:0044281|GO:0031323|GO:0005975|GO:0048871|GO:0044262|GO:0044255|GO:0015980|GO:0007165|GO:0007049|GO:0042180|GO:0007154|GO:0045787|GO:0051726|GO:0051248|GO:0010628|GO:0005829|GO:0032269|GO:0006112|GO:0008610|GO:0031328|GO:0019693|GO:0010468|GO:0071157|GO:0005634|GO:0016052|GO:0009756|GO:0046434|GO:0009116|GO:0007050|GO:0044267|GO:0044275|GO:0010629|GO:0005654|GO:0010557|GO:0009059|GO:0046890|GO:0051174|GO:0045923|GO:0010564|GO:0019439|GO:0097009|GO:0003677|GO:0006757|GO:0043412|GO:0051252|GO:0031981|GO:0006631|GO:0000982|GO:0034655|GO:0019216|GO:0010565|GO:0051246|GO:0035556|GO:0046889|GO:0034645|GO:0010467|GO:0006796|GO:0048878|GO:0001227|GO:0016070|GO:0055082|GO:0032268|GO:0046982|GO:0006119|GO:0071310|GO:0009743|GO:0006163|GO:0009117|GO:0071156|GO:0032774|GO:0006464|GO:0045723|GO:0009259|GO:0006351|GO:0042304|GO:0042278|GO:0006110|GO:0001678|GO:0006633|GO:0045892|GO:0009166|GO:0071322|GO:0045893|GO:0016310|GO:0055088|GO:0050801|GO:0034284|GO:0009132|GO:0006355|GO:0045821|GO:0090324|GO:0000975|GO:1902679|GO:0045980|GO:0019752|GO:0006096|GO:0043565|GO:0001078|GO:0019217|GO:0003690|GO:0002082|GO:2001141|GO:0006357|GO:0006165|GO:1903506|GO:0046939|GO:1903578|GO:0042593|GO:0001932|GO:0018193|GO:0042326|GO:0055081|GO:0071333|GO:1903507|GO:0001933|GO:0044212|GO:0055089|GO:0032787|GO:0042327|GO:0042325|GO:0006366|GO:0046496|GO:0000122|GO:0006468|GO:0045944|GO:0033137|GO:0035538|GO:0070328|GO:0046031|GO:0009749|GO:0001012|GO:0010255|GO:0001159|GO:0018105|GO:0033135|GO:0046034|GO:0000976|GO:0006090|GO:0000977|GO:0000987|GO:0000978 "nucleic acid binding transcription factor activity|signaling|cell|response to stimulus|organelle|cellular process|metabolic process|developmental process|macromolecular complex|binding|positive regulation of metabolic process|cell proliferation|catabolic process|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|regulation of cellular process|biosynthetic process|cellular response to stimulus|transcription factor activity, sequence-specific DNA binding|nitrogen compound metabolic process|organic cyclic compound binding|protein binding|anatomical structure morphogenesis|regulation of metabolic process|negative regulation of metabolic process|negative regulation of cellular process|protein complex|membrane-bounded organelle|organic substance metabolic process|response to organic substance|homeostatic process|transcription factor complex|regulation of energy homeostasis|RNA polymerase II transcription factor activity, sequence-specific DNA binding|organic cyclic compound metabolic process|cytoplasm|cellular homeostasis|oxidation-reduction process|cellular biosynthetic process|nucleobase-containing compound metabolic process|organic acid metabolic process|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|protein dimerization activity|cofactor metabolic process|generation of precursor metabolites and energy|transcription factor binding|cellular aromatic compound metabolic process|negative regulation of biosynthetic process|nucleobase-containing small molecule metabolic process|positive regulation of cellular metabolic process|lipid metabolic process|protein metabolic process|negative regulation of cellular metabolic process|organophosphate metabolic process|regulation of cell proliferation|negative regulation of cell cycle|nucleic acid binding|heterocycle metabolic process|positive regulation of cell proliferation|small molecule metabolic process|regulation of cellular metabolic process|carbohydrate metabolic process|multicellular organismal homeostasis|cellular carbohydrate metabolic process|cellular lipid metabolic process|energy derivation by oxidation of organic compounds|signal transduction|cell cycle|cellular ketone metabolic process|cell communication|positive regulation of cell cycle|regulation of cell cycle|negative regulation of protein metabolic process|positive regulation of gene expression|cytosol|negative regulation of cellular protein metabolic process|energy reserve metabolic process|lipid biosynthetic process|positive regulation of cellular biosynthetic process|ribose phosphate metabolic process|regulation of gene expression|negative regulation of cell cycle arrest|nucleus|carbohydrate catabolic process|carbohydrate mediated signaling|organophosphate catabolic process|nucleoside metabolic process|cell cycle arrest|cellular protein metabolic process|cellular carbohydrate catabolic process|negative regulation of gene expression|nucleoplasm|positive regulation of macromolecule biosynthetic process|macromolecule biosynthetic process|regulation of lipid biosynthetic process|regulation of phosphorus metabolic process|positive regulation of fatty acid metabolic process|regulation of cell cycle process|aromatic compound catabolic process|energy homeostasis|DNA binding|ATP generation from ADP|macromolecule modification|regulation of RNA metabolic process|nuclear lumen|fatty acid metabolic process|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding|nucleobase-containing compound catabolic process|regulation of lipid metabolic process|regulation of cellular ketone metabolic process|regulation of protein metabolic process|intracellular signal transduction|positive regulation of lipid biosynthetic process|cellular macromolecule biosynthetic process|gene expression|phosphate-containing compound metabolic process|chemical homeostasis|transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding|RNA metabolic process|cellular chemical homeostasis|regulation of cellular protein metabolic process|protein heterodimerization activity|oxidative phosphorylation|cellular response to organic substance|response to carbohydrate|purine nucleotide metabolic process|nucleotide metabolic process|regulation of cell cycle arrest|RNA biosynthetic process|cellular protein modification process|positive regulation of fatty acid biosynthetic process|ribonucleotide metabolic process|transcription, DNA-templated|regulation of fatty acid biosynthetic process|purine nucleoside metabolic process|regulation of glycolytic process|cellular glucose homeostasis|fatty acid biosynthetic process|negative regulation of transcription, DNA-templated|nucleotide catabolic process|cellular response to carbohydrate stimulus|positive regulation of transcription, DNA-templated|phosphorylation|lipid homeostasis|ion homeostasis|response to monosaccharide|nucleoside diphosphate metabolic process|regulation of transcription, DNA-templated|positive regulation of glycolytic process|negative regulation of oxidative phosphorylation|regulatory region DNA binding|negative regulation of RNA biosynthetic process|negative regulation of nucleotide metabolic process|carboxylic acid metabolic process|glycolytic process|sequence-specific DNA binding|transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding|regulation of fatty acid metabolic process|double-stranded DNA binding|regulation of oxidative phosphorylation|regulation of RNA biosynthetic process|regulation of transcription from RNA polymerase II promoter|nucleoside diphosphate phosphorylation|regulation of nucleic acid-templated transcription|nucleotide phosphorylation|regulation of ATP metabolic process|glucose homeostasis|regulation of protein phosphorylation|peptidyl-amino acid modification|negative regulation of phosphorylation|anion homeostasis|cellular response to glucose stimulus|negative regulation of nucleic acid-templated transcription|negative regulation of protein phosphorylation|transcription regulatory region DNA binding|fatty acid homeostasis|monocarboxylic acid metabolic process|positive regulation of phosphorylation|regulation of phosphorylation|transcription from RNA polymerase II promoter|nicotinamide nucleotide metabolic process|negative regulation of transcription from RNA polymerase II promoter|protein phosphorylation|positive regulation of transcription from RNA polymerase II promoter|negative regulation of peptidyl-serine phosphorylation|carbohydrate response element binding|triglyceride homeostasis|ADP metabolic process|response to glucose|RNA polymerase II regulatory region DNA binding|glucose mediated signaling pathway|core promoter proximal region DNA binding|peptidyl-serine phosphorylation|regulation of peptidyl-serine phosphorylation|ATP metabolic process|transcription regulatory region sequence-specific DNA binding|pyruvate metabolic process|RNA polymerase II regulatory region sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding" K09113 MAX-like protein X[-] hsa04932|hsa04931 Non-alcoholic fatty liver disease (NAFLD) - Homo sapiens (human)|Insulin resistance - Homo sapiens (human) chr7:73007524-73038873 3.571688005 1.200855868 1.57254306 3.10E-06 0.00028414 UP ENSG00000187260 WDR86 WD repeat domain 86 [Source:HGNC Symbol;Acc:HGNC:28020] - - - - - - chr7:151078207-151107813 3.394386935 1.282463707 1.404233032 3.13E-06 0.00028521 UP ENSG00000198739 LRRTM3 leucine rich repeat transmembrane neuronal 3 [Source:HGNC Symbol;Acc:HGNC:19410] GO:0016020|GO:0005623|GO:0030054|GO:0009987|GO:0045202|GO:0008152|GO:0032502|GO:0005488|GO:0009893|GO:0031224|GO:0097060|GO:0048856|GO:0044237|GO:0016043|GO:0050794|GO:0006807|GO:0071944|GO:0005886|GO:0005515|GO:0019222|GO:0050793|GO:0071704|GO:0051128|GO:0051963|GO:0045211|GO:0048731|GO:0007275|GO:0022607|GO:0034641|GO:0051965|GO:0050803|GO:0016021|GO:0031325|GO:0019538|GO:0031323|GO:0050808|GO:0051130|GO:0006518|GO:0042982|GO:0007399|GO:0050807|GO:0051247|GO:0051960|GO:0007416|GO:0051246|GO:0043603|GO:1902003|GO:1902004|GO:0042987|GO:1902991|GO:0050435|GO:0034205 membrane|cell|cell junction|cellular process|synapse|metabolic process|developmental process|binding|positive regulation of metabolic process|intrinsic component of membrane|synaptic membrane|anatomical structure development|cellular metabolic process|cellular component organization|regulation of cellular process|nitrogen compound metabolic process|cell periphery|plasma membrane|protein binding|regulation of metabolic process|regulation of developmental process|organic substance metabolic process|regulation of cellular component organization|regulation of synapse assembly|postsynaptic membrane|system development|multicellular organism development|cellular component assembly|cellular nitrogen compound metabolic process|positive regulation of synapse assembly|regulation of synapse structure or activity|integral component of membrane|positive regulation of cellular metabolic process|protein metabolic process|regulation of cellular metabolic process|synapse organization|positive regulation of cellular component organization|peptide metabolic process|amyloid precursor protein metabolic process|nervous system development|regulation of synapse organization|positive regulation of protein metabolic process|regulation of nervous system development|synapse assembly|regulation of protein metabolic process|cellular amide metabolic process|regulation of beta-amyloid formation|positive regulation of beta-amyloid formation|amyloid precursor protein catabolic process|regulation of amyloid precursor protein catabolic process|beta-amyloid metabolic process|beta-amyloid formation - - - - chr10:68685764-68859588 0.418504947 0.045910241 3.188356764 4.04E-06 0.000344959 UP ENSG00000003096 KLHL13 kelch like family member 13 [Source:HGNC Symbol;Acc:HGNC:22931] GO:0005623|GO:0003824|GO:0009987|GO:0008152|GO:0032991|GO:0005488|GO:0005622|GO:0044237|GO:0016043|GO:0005515|GO:0016740|GO:0043234|GO:0071704|GO:0051301|GO:0000151|GO:0019787|GO:0019538|GO:0006996|GO:0007049|GO:1903047|GO:0044267|GO:0004842|GO:0043412|GO:0007067|GO:0031461|GO:0000278|GO:1990234|GO:0000910|GO:0006464|GO:0031463|GO:0032446|GO:0016567 cell|catalytic activity|cellular process|metabolic process|macromolecular complex|binding|intracellular|cellular metabolic process|cellular component organization|protein binding|transferase activity|protein complex|organic substance metabolic process|cell division|ubiquitin ligase complex|ubiquitin-like protein transferase activity|protein metabolic process|organelle organization|cell cycle|mitotic cell cycle process|cellular protein metabolic process|ubiquitin-protein transferase activity|macromolecule modification|mitotic nuclear division|cullin-RING ubiquitin ligase complex|mitotic cell cycle|transferase complex|cytokinesis|cellular protein modification process|Cul3-RING ubiquitin ligase complex|protein modification by small protein conjugation|protein ubiquitination K10447 kelch-like protein 9/13[-] hsa04120 Ubiquitin mediated proteolysis - Homo sapiens (human) chrX:117031776-117251303 8.299903272 3.866101351 1.102215065 4.19E-06 0.000353401 UP ENSG00000124205 EDN3 endothelin 3 [Source:HGNC Symbol;Acc:HGNC:3178] GO:0023052|GO:0005576|GO:0040011|GO:0050896|GO:0002376|GO:0007610|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0009893|GO:0048870|GO:0002684|GO:0043473|GO:0008283|GO:0050795|GO:0048520|GO:0040017|GO:0048856|GO:0044237|GO:0051050|GO:0016043|GO:0050794|GO:0051716|GO:0009605|GO:0040012|GO:0051641|GO:0050900|GO:0005515|GO:0019222|GO:0050793|GO:0005615|GO:0002682|GO:0071704|GO:0051302|GO:0042592|GO:0051128|GO:0050921|GO:0010817|GO:0048070|GO:0055085|GO:0046887|GO:0071804|GO:0005102|GO:0048468|GO:0007267|GO:0003012|GO:0009888|GO:2000145|GO:0051272|GO:0048731|GO:0051781|GO:0019725|GO:0016477|GO:0051301|GO:0030595|GO:0003013|GO:0043085|GO:0048869|GO:0050920|GO:0008217|GO:0060341|GO:0007275|GO:0009966|GO:0002027|GO:0009967|GO:0006928|GO:0050790|GO:0006810|GO:0032940|GO:2000147|GO:0046883|GO:0031325|GO:0019538|GO:0042127|GO:0051270|GO:0002685|GO:0043270|GO:0008284|GO:0006935|GO:0031323|GO:0051130|GO:0048513|GO:0006996|GO:0007165|GO:0007049|GO:0051047|GO:0023014|GO:0010646|GO:0007154|GO:0002687|GO:0045787|GO:0048066|GO:0051726|GO:0030334|GO:0045931|GO:0001667|GO:0043269|GO:0048864|GO:0090068|GO:0060326|GO:0046903|GO:0030154|GO:0035150|GO:0003073|GO:0006811|GO:0060485|GO:1903047|GO:0060429|GO:0044267|GO:0042886|GO:0032270|GO:0007399|GO:0051174|GO:0071805|GO:0000165|GO:0006936|GO:0010564|GO:0010460|GO:0051247|GO:0043412|GO:0071621|GO:0051347|GO:0007067|GO:0034765|GO:0043268|GO:0045823|GO:0051246|GO:0000278|GO:0034220|GO:0035556|GO:0009914|GO:0008015|GO:1902533|GO:0006796|GO:0048878|GO:0002690|GO:0051046|GO:0010638|GO:0005179|GO:0007166|GO:0030335|GO:0007346|GO:0055082|GO:0032268|GO:0033043|GO:0034767|GO:0006873|GO:0043549|GO:0022008|GO:0033674|GO:0003100|GO:0014031|GO:0006464|GO:0001755|GO:0030593|GO:0048762|GO:1901381|GO:0016310|GO:0045840|GO:0050801|GO:0030318|GO:1990266|GO:0050880|GO:0048863|GO:0031401|GO:0043408|GO:0019229|GO:0019932|GO:0015833|GO:1901379|GO:0007088|GO:0060047|GO:0046879|GO:0006812|GO:0098655|GO:0030182|GO:0006939|GO:0008016|GO:0043410|GO:0002790|GO:0030855|GO:0043406|GO:0048699|GO:0045860|GO:0030072|GO:0001932|GO:0015672|GO:0001934|GO:0014032|GO:0042310|GO:0030003|GO:0042327|GO:0048016|GO:0042325|GO:0014829|GO:0006468|GO:0030001|GO:0014033|GO:0043405|GO:0043266|GO:0045859|GO:0071902|GO:0055065|GO:0006813|GO:0014826|GO:0060563|GO:0006875|GO:0010960|GO:0055074|GO:0006874|GO:0010961 signaling|extracellular region|locomotion|response to stimulus|immune system process|behavior|cellular process|metabolic process|developmental process|binding|positive regulation of metabolic process|cell motility|positive regulation of immune system process|pigmentation|cell proliferation|regulation of behavior|positive regulation of behavior|positive regulation of locomotion|anatomical structure development|cellular metabolic process|positive regulation of transport|cellular component organization|regulation of cellular process|cellular response to stimulus|response to external stimulus|regulation of locomotion|cellular localization|leukocyte migration|protein binding|regulation of metabolic process|regulation of developmental process|extracellular space|regulation of immune system process|organic substance metabolic process|regulation of cell division|homeostatic process|regulation of cellular component organization|positive regulation of chemotaxis|regulation of hormone levels|regulation of developmental pigmentation|transmembrane transport|positive regulation of hormone secretion|cellular potassium ion transport|receptor binding|cell development|cell-cell signaling|muscle system process|tissue development|regulation of cell motility|positive regulation of cellular component movement|system development|positive regulation of cell division|cellular homeostasis|cell migration|cell division|leukocyte chemotaxis|circulatory system process|positive regulation of catalytic activity|cellular developmental process|regulation of chemotaxis|regulation of blood pressure|regulation of cellular localization|multicellular organism development|regulation of signal transduction|regulation of heart rate|positive regulation of signal transduction|movement of cell or subcellular component|regulation of catalytic activity|transport|secretion by cell|positive regulation of cell motility|regulation of hormone secretion|positive regulation of cellular metabolic process|protein metabolic process|regulation of cell proliferation|regulation of cellular component movement|regulation of leukocyte migration|positive regulation of ion transport|positive regulation of cell proliferation|chemotaxis|regulation of cellular metabolic process|positive regulation of cellular component organization|animal organ development|organelle organization|signal transduction|cell cycle|positive regulation of secretion|signal transduction by protein phosphorylation|regulation of cell communication|cell communication|positive regulation of leukocyte migration|positive regulation of cell cycle|developmental pigmentation|regulation of cell cycle|regulation of cell migration|positive regulation of mitotic cell cycle|ameboidal-type cell migration|regulation of ion transport|stem cell development|positive regulation of cell cycle process|cell chemotaxis|secretion|cell differentiation|regulation of tube size|regulation of systemic arterial blood pressure|ion transport|mesenchyme development|mitotic cell cycle process|epithelium development|cellular protein metabolic process|amide transport|positive regulation of cellular protein metabolic process|nervous system development|regulation of phosphorus metabolic process|potassium ion transmembrane transport|MAPK cascade|muscle contraction|regulation of cell cycle process|positive regulation of heart rate|positive regulation of protein metabolic process|macromolecule modification|granulocyte chemotaxis|positive regulation of transferase activity|mitotic nuclear division|regulation of ion transmembrane transport|positive regulation of potassium ion transport|positive regulation of heart contraction|regulation of protein metabolic process|mitotic cell cycle|ion transmembrane transport|intracellular signal transduction|hormone transport|blood circulation|positive regulation of intracellular signal transduction|phosphate-containing compound metabolic process|chemical homeostasis|positive regulation of leukocyte chemotaxis|regulation of secretion|positive regulation of organelle organization|hormone activity|cell surface receptor signaling pathway|positive regulation of cell migration|regulation of mitotic cell cycle|cellular chemical homeostasis|regulation of cellular protein metabolic process|regulation of organelle organization|positive regulation of ion transmembrane transport|cellular ion homeostasis|regulation of kinase activity|neurogenesis|positive regulation of kinase activity|regulation of systemic arterial blood pressure by endothelin|mesenchymal cell development|cellular protein modification process|neural crest cell migration|neutrophil chemotaxis|mesenchymal cell differentiation|positive regulation of potassium ion transmembrane transport|phosphorylation|positive regulation of mitotic nuclear division|ion homeostasis|melanocyte differentiation|neutrophil migration|regulation of blood vessel size|stem cell differentiation|positive regulation of protein modification process|regulation of MAPK cascade|regulation of vasoconstriction|second-messenger-mediated signaling|peptide transport|regulation of potassium ion transmembrane transport|regulation of mitotic nuclear division|heart contraction|hormone secretion|cation transport|cation transmembrane transport|neuron differentiation|smooth muscle contraction|regulation of heart contraction|positive regulation of MAPK cascade|peptide secretion|epithelial cell differentiation|positive regulation of MAP kinase activity|generation of neurons|positive regulation of protein kinase activity|peptide hormone secretion|regulation of protein phosphorylation|monovalent inorganic cation transport|positive regulation of protein phosphorylation|neural crest cell development|vasoconstriction|cellular cation homeostasis|positive regulation of phosphorylation|inositol phosphate-mediated signaling|regulation of phosphorylation|vascular smooth muscle contraction|protein phosphorylation|metal ion transport|neural crest cell differentiation|regulation of MAP kinase activity|regulation of potassium ion transport|regulation of protein kinase activity|positive regulation of protein serine/threonine kinase activity|metal ion homeostasis|potassium ion transport|vein smooth muscle contraction|neuroepithelial cell differentiation|cellular metal ion homeostasis|magnesium ion homeostasis|calcium ion homeostasis|cellular calcium ion homeostasis|cellular magnesium ion homeostasis - - - - chr20:57875482-57901047 0.484204653 0.094780728 2.352951296 4.96E-06 0.000396378 UP ENSG00000133317 LGALS12 "lectin, galactoside-binding, soluble, 12 [Source:HGNC Symbol;Acc:HGNC:15788]" GO:0023052|GO:0005623|GO:0050896|GO:0043226|GO:0009987|GO:0005488|GO:0005622|GO:0043229|GO:0030246|GO:0050794|GO:0051716|GO:0043227|GO:0005737|GO:0043231|GO:0008219|GO:0070492|GO:0007165|GO:0007154|GO:0005634|GO:0005739|GO:0035556|GO:0097190|GO:0012501|GO:0097193|GO:0030395|GO:0006915 signaling|cell|response to stimulus|organelle|cellular process|binding|intracellular|intracellular organelle|carbohydrate binding|regulation of cellular process|cellular response to stimulus|membrane-bounded organelle|cytoplasm|intracellular membrane-bounded organelle|cell death|oligosaccharide binding|signal transduction|cell communication|nucleus|mitochondrion|intracellular signal transduction|apoptotic signaling pathway|programmed cell death|intrinsic apoptotic signaling pathway|lactose binding|apoptotic process - - - - chr11:63273556-63284246 0.053777719 0.001800759 4.900331223 5.86E-06 0.000457254 UP ENSG00000103253 HAGHL hydroxyacylglutathione hydrolase-like [Source:HGNC Symbol;Acc:HGNC:14177] GO:0003824|GO:0009987|GO:0008152|GO:0005488|GO:0044237|GO:0009058|GO:0043167|GO:0006807|GO:0016787|GO:0071704|GO:0016788|GO:0044249|GO:0006575|GO:0034641|GO:0006790|GO:0043169|GO:0006518|GO:0016790|GO:0006749|GO:0046872|GO:0043603|GO:0043043|GO:0046914|GO:0006750|GO:0004416|GO:0008270 "catalytic activity|cellular process|metabolic process|binding|cellular metabolic process|biosynthetic process|ion binding|nitrogen compound metabolic process|hydrolase activity|organic substance metabolic process|hydrolase activity, acting on ester bonds|cellular biosynthetic process|cellular modified amino acid metabolic process|cellular nitrogen compound metabolic process|sulfur compound metabolic process|cation binding|peptide metabolic process|thiolester hydrolase activity|glutathione metabolic process|metal ion binding|cellular amide metabolic process|peptide biosynthetic process|transition metal ion binding|glutathione biosynthetic process|hydroxyacylglutathione hydrolase activity|zinc ion binding" K01069 hydroxyacylglutathione hydrolase[3.1.2.6] hsa00620 Pyruvate metabolism - Homo sapiens (human) chr16:776936-779733 0.84007481 0.351676538 1.25626872 6.84E-06 0.000516316 UP ENSG00000146674 IGFBP3 insulin like growth factor binding protein 3 [Source:HGNC Symbol;Acc:HGNC:5472] GO:0023052|GO:0005576|GO:0040011|GO:0005623|GO:0050896|GO:0040007|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0032991|GO:0005488|GO:0009893|GO:0023057|GO:0048870|GO:0008283|GO:0040008|GO:0005622|GO:0043229|GO:0016942|GO:0048856|GO:0044237|GO:0016043|GO:0040013|GO:0050794|GO:0051716|GO:0043167|GO:0040012|GO:0030234|GO:0005515|GO:0019222|GO:0050793|GO:0009892|GO:0048523|GO:0043234|GO:0016049|GO:0005615|GO:0043227|GO:0071704|GO:0051128|GO:0051271|GO:0001968|GO:0019208|GO:0008285|GO:2000145|GO:0045597|GO:2000146|GO:0016477|GO:0045595|GO:0009968|GO:0001503|GO:0043085|GO:0048869|GO:0009966|GO:0043231|GO:0070062|GO:0009967|GO:0006928|GO:0050790|GO:0010942|GO:0008047|GO:0008219|GO:0061061|GO:0031325|GO:0019538|GO:0031324|GO:0042127|GO:0051270|GO:0043169|GO:0050673|GO:0044281|GO:0031323|GO:0031982|GO:0005975|GO:0044262|GO:0001558|GO:0007165|GO:0019838|GO:0023014|GO:0010646|GO:0007154|GO:0010941|GO:0030334|GO:0051248|GO:0043068|GO:0044342|GO:0032269|GO:0048660|GO:0005634|GO:0030336|GO:0030154|GO:0051147|GO:0044267|GO:0048659|GO:0001649|GO:0042692|GO:0051149|GO:0032270|GO:0043567|GO:0005520|GO:0051174|GO:0000165|GO:0019211|GO:0051247|GO:0043067|GO:0043412|GO:0019888|GO:0046872|GO:0051246|GO:0014812|GO:0035556|GO:1902533|GO:0006796|GO:0043568|GO:0007166|GO:0012501|GO:0032268|GO:0048662|GO:0005996|GO:0031994|GO:0045661|GO:0006464|GO:0014912|GO:0072542|GO:0016310|GO:0014910|GO:0045445|GO:0045663|GO:0043065|GO:0010906|GO:0031401|GO:0043408|GO:0006915|GO:0014909|GO:0042981|GO:0019318|GO:0031995|GO:0007167|GO:0043410|GO:0001932|GO:0042326|GO:0001934|GO:0001933|GO:0007169|GO:0006006|GO:0042327|GO:0042325|GO:0008160|GO:0006468|GO:0048009 signaling|extracellular region|locomotion|cell|response to stimulus|growth|organelle|cellular process|metabolic process|developmental process|macromolecular complex|binding|positive regulation of metabolic process|negative regulation of signaling|cell motility|cell proliferation|regulation of growth|intracellular|intracellular organelle|insulin-like growth factor binding protein complex|anatomical structure development|cellular metabolic process|cellular component organization|negative regulation of locomotion|regulation of cellular process|cellular response to stimulus|ion binding|regulation of locomotion|enzyme regulator activity|protein binding|regulation of metabolic process|regulation of developmental process|negative regulation of metabolic process|negative regulation of cellular process|protein complex|cell growth|extracellular space|membrane-bounded organelle|organic substance metabolic process|regulation of cellular component organization|negative regulation of cellular component movement|fibronectin binding|phosphatase regulator activity|negative regulation of cell proliferation|regulation of cell motility|positive regulation of cell differentiation|negative regulation of cell motility|cell migration|regulation of cell differentiation|negative regulation of signal transduction|ossification|positive regulation of catalytic activity|cellular developmental process|regulation of signal transduction|intracellular membrane-bounded organelle|extracellular exosome|positive regulation of signal transduction|movement of cell or subcellular component|regulation of catalytic activity|positive regulation of cell death|enzyme activator activity|cell death|muscle structure development|positive regulation of cellular metabolic process|protein metabolic process|negative regulation of cellular metabolic process|regulation of cell proliferation|regulation of cellular component movement|cation binding|epithelial cell proliferation|small molecule metabolic process|regulation of cellular metabolic process|vesicle|carbohydrate metabolic process|cellular carbohydrate metabolic process|regulation of cell growth|signal transduction|growth factor binding|signal transduction by protein phosphorylation|regulation of cell communication|cell communication|regulation of cell death|regulation of cell migration|negative regulation of protein metabolic process|positive regulation of programmed cell death|type B pancreatic cell proliferation|negative regulation of cellular protein metabolic process|regulation of smooth muscle cell proliferation|nucleus|negative regulation of cell migration|cell differentiation|regulation of muscle cell differentiation|cellular protein metabolic process|smooth muscle cell proliferation|osteoblast differentiation|muscle cell differentiation|positive regulation of muscle cell differentiation|positive regulation of cellular protein metabolic process|regulation of insulin-like growth factor receptor signaling pathway|insulin-like growth factor binding|regulation of phosphorus metabolic process|MAPK cascade|phosphatase activator activity|positive regulation of protein metabolic process|regulation of programmed cell death|macromolecule modification|protein phosphatase regulator activity|metal ion binding|regulation of protein metabolic process|muscle cell migration|intracellular signal transduction|positive regulation of intracellular signal transduction|phosphate-containing compound metabolic process|positive regulation of insulin-like growth factor receptor signaling pathway|cell surface receptor signaling pathway|programmed cell death|regulation of cellular protein metabolic process|negative regulation of smooth muscle cell proliferation|monosaccharide metabolic process|insulin-like growth factor I binding|regulation of myoblast differentiation|cellular protein modification process|negative regulation of smooth muscle cell migration|protein phosphatase activator activity|phosphorylation|regulation of smooth muscle cell migration|myoblast differentiation|positive regulation of myoblast differentiation|positive regulation of apoptotic process|regulation of glucose metabolic process|positive regulation of protein modification process|regulation of MAPK cascade|apoptotic process|smooth muscle cell migration|regulation of apoptotic process|hexose metabolic process|insulin-like growth factor II binding|enzyme linked receptor protein signaling pathway|positive regulation of MAPK cascade|regulation of protein phosphorylation|negative regulation of phosphorylation|positive regulation of protein phosphorylation|negative regulation of protein phosphorylation|transmembrane receptor protein tyrosine kinase signaling pathway|glucose metabolic process|positive regulation of phosphorylation|regulation of phosphorylation|protein tyrosine phosphatase activator activity|protein phosphorylation|insulin-like growth factor receptor signaling pathway K10138 insulin-like growth factor-binding protein 3[-] hsa05202|hsa04115 Transcriptional misregulation in cancer - Homo sapiens (human)|p53 signaling pathway - Homo sapiens (human) chr7:45951949-45961473 336.4009722 138.1633722 1.283806674 7.21E-06 0.00054067 UP ENSG00000125355 TMEM255A transmembrane protein 255A [Source:HGNC Symbol;Acc:HGNC:26086] GO:0016020|GO:0031224|GO:0016021 membrane|intrinsic component of membrane|integral component of membrane - - - - chrX:119392505-119445411 1.783177244 0.586166004 1.605068909 7.82E-06 0.000581665 UP ENSG00000171819 ANGPTL7 angiopoietin like 7 [Source:HGNC Symbol;Acc:HGNC:24078] - - - - - - chr1:11249398-11256038 24.22356536 7.0724385 1.776131593 9.54E-06 0.000673855 UP ENSG00000181074 OR52N4 olfactory receptor family 52 subfamily N member 4 (gene/pseudogene) [Source:HGNC Symbol;Acc:HGNC:15230] - - K04257 olfactory receptor[-] hsa04740 Olfactory transduction - Homo sapiens (human) chr11:5775923-5776959 1.244338899 0.385618215 1.690134356 1.46E-05 0.000921426 UP ENSG00000064692 SNCAIP synuclein alpha interacting protein [Source:HGNC Symbol;Acc:HGNC:11139] GO:0023052|GO:0016020|GO:0005623|GO:0043226|GO:0009987|GO:0045202|GO:0008152|GO:0005488|GO:0012505|GO:0097060|GO:0005622|GO:0043229|GO:0044237|GO:0016043|GO:0008021|GO:0050794|GO:0051641|GO:0007269|GO:0006807|GO:0071944|GO:0005886|GO:0005515|GO:0044297|GO:0043227|GO:0071704|GO:0051128|GO:0007267|GO:0090083|GO:0050804|GO:1901360|GO:0005737|GO:0060341|GO:0022607|GO:0043231|GO:0042734|GO:0001505|GO:0030133|GO:0019899|GO:0006810|GO:0042802|GO:0032940|GO:0006725|GO:0008219|GO:0046928|GO:0051649|GO:0036477|GO:0031982|GO:0010646|GO:0043025|GO:0007154|GO:0006584|GO:0018958|GO:0046903|GO:0044389|GO:0042417|GO:0070382|GO:0006836|GO:0031410|GO:0051046|GO:0016023|GO:0031988|GO:0009712|GO:0031625|GO:0007268 "signaling|membrane|cell|organelle|cellular process|synapse|metabolic process|binding|endomembrane system|synaptic membrane|intracellular|intracellular organelle|cellular metabolic process|cellular component organization|synaptic vesicle|regulation of cellular process|cellular localization|neurotransmitter secretion|nitrogen compound metabolic process|cell periphery|plasma membrane|protein binding|cell body|membrane-bounded organelle|organic substance metabolic process|regulation of cellular component organization|cell-cell signaling|regulation of inclusion body assembly|modulation of synaptic transmission|organic cyclic compound metabolic process|cytoplasm|regulation of cellular localization|cellular component assembly|intracellular membrane-bounded organelle|presynaptic membrane|regulation of neurotransmitter levels|transport vesicle|enzyme binding|transport|identical protein binding|secretion by cell|cellular aromatic compound metabolic process|cell death|regulation of neurotransmitter secretion|establishment of localization in cell|somatodendritic compartment|vesicle|regulation of cell communication|neuronal cell body|cell communication|catecholamine metabolic process|phenol-containing compound metabolic process|secretion|ubiquitin-like protein ligase binding|dopamine metabolic process|exocytic vesicle|neurotransmitter transport|cytoplasmic vesicle|regulation of secretion|cytoplasmic, membrane-bounded vesicle|membrane-bounded vesicle|catechol-containing compound metabolic process|ubiquitin protein ligase binding|synaptic transmission" K04558 "synuclein, alpha interacting protein (synphilin)[-]" hsa05012 Parkinson's disease - Homo sapiens (human) chr5:121647049-121799914 3.879765154 1.872612519 1.05091692 1.64E-05 0.00101139 UP ENSG00000152578 GRIA4 "glutamate receptor, ionotropic, AMPA 4 [Source:HGNC Symbol;Acc:HGNC:4574]" GO:0023052|GO:0016020|GO:0005623|GO:0030054|GO:0050896|GO:0004871|GO:0005215|GO:0043226|GO:0009987|GO:0045202|GO:0032991|GO:0005488|GO:0038023|GO:0031224|GO:0031090|GO:0097060|GO:0005622|GO:0043229|GO:0022857|GO:0050794|GO:0051716|GO:0042995|GO:0071944|GO:0005886|GO:0005515|GO:0043234|GO:0043227|GO:0004872|GO:0043235|GO:0004888|GO:0055085|GO:0030594|GO:0007267|GO:0045211|GO:0022891|GO:0043005|GO:0005737|GO:0031226|GO:0043231|GO:0006810|GO:0016021|GO:0005887|GO:0012506|GO:1902495|GO:0098588|GO:0036477|GO:0031982|GO:0007165|GO:0030666|GO:0007154|GO:0030659|GO:0034702|GO:0008066|GO:0015075|GO:0006811|GO:0031410|GO:0030425|GO:0034220|GO:0008328|GO:0007166|GO:0015267|GO:0016023|GO:0031988|GO:0022824|GO:0005216|GO:0007215|GO:0015276|GO:0032281|GO:0004970|GO:0030139|GO:0004971|GO:0007268|GO:0005230|GO:0035235|GO:0005231|GO:0007270|GO:0005234|GO:0035249 "signaling|membrane|cell|cell junction|response to stimulus|signal transducer activity|transporter activity|organelle|cellular process|synapse|macromolecular complex|binding|signaling receptor activity|intrinsic component of membrane|organelle membrane|synaptic membrane|intracellular|intracellular organelle|transmembrane transporter activity|regulation of cellular process|cellular response to stimulus|cell projection|cell periphery|plasma membrane|protein binding|protein complex|membrane-bounded organelle|receptor activity|receptor complex|transmembrane signaling receptor activity|transmembrane transport|neurotransmitter receptor activity|cell-cell signaling|postsynaptic membrane|substrate-specific transmembrane transporter activity|neuron projection|cytoplasm|intrinsic component of plasma membrane|intracellular membrane-bounded organelle|transport|integral component of membrane|integral component of plasma membrane|vesicle membrane|transmembrane transporter complex|bounding membrane of organelle|somatodendritic compartment|vesicle|signal transduction|endocytic vesicle membrane|cell communication|cytoplasmic vesicle membrane|ion channel complex|glutamate receptor activity|ion transmembrane transporter activity|ion transport|cytoplasmic vesicle|dendrite|ion transmembrane transport|ionotropic glutamate receptor complex|cell surface receptor signaling pathway|channel activity|cytoplasmic, membrane-bounded vesicle|membrane-bounded vesicle|transmitter-gated ion channel activity|ion channel activity|glutamate receptor signaling pathway|ligand-gated ion channel activity|AMPA glutamate receptor complex|ionotropic glutamate receptor activity|endocytic vesicle|AMPA glutamate receptor activity|synaptic transmission|extracellular ligand-gated ion channel activity|ionotropic glutamate receptor signaling pathway|excitatory extracellular ligand-gated ion channel activity|neuron-neuron synaptic transmission|extracellular-glutamate-gated ion channel activity|synaptic transmission, glutamatergic" K05200 glutamate receptor 4[-] hsa04080|hsa04024|hsa04728|hsa04724|hsa04723|hsa04713|hsa05031|hsa05033 Neuroactive ligand-receptor interaction - Homo sapiens (human)|cAMP signaling pathway - Homo sapiens (human)|Dopaminergic synapse - Homo sapiens (human)|Glutamatergic synapse - Homo sapiens (human)|Retrograde endocannabinoid signaling - Homo sapiens (human)|Circadian entrainment - Homo sapiens (human)|Amphetamine addiction - Homo sapiens (human)|Nicotine addiction - Homo sapiens (human) chr11:105480721-105852819 0.269420002 0.11309288 1.252348863 1.83E-05 0.001097974 UP ENSG00000128578 STRIP2 striatin interacting protein 2 [Source:HGNC Symbol;Acc:HGNC:22209] - - - - - - chr7:129074274-129128240 11.14730793 4.56183537 1.289009054 1.92E-05 0.001128048 UP ENSG00000081479 LRP2 LDL receptor related protein 2 [Source:HGNC Symbol;Acc:HGNC:6694] GO:0023052|GO:0005576|GO:0016020|GO:0005623|GO:0050896|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0032991|GO:0005488|GO:0012505|GO:0008283|GO:0031224|GO:0031090|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0050794|GO:0009058|GO:0051716|GO:0009605|GO:0043167|GO:0042995|GO:0071944|GO:0005886|GO:0005515|GO:0005905|GO:0051606|GO:0045177|GO:0043234|GO:0043227|GO:0009628|GO:0071704|GO:0043235|GO:0007420|GO:0005774|GO:0048731|GO:1901360|GO:0005737|GO:0009582|GO:0044249|GO:0031253|GO:0007275|GO:0043231|GO:0070062|GO:0005794|GO:0009314|GO:0006810|GO:0016324|GO:0016021|GO:0030900|GO:0005768|GO:0006629|GO:0019538|GO:0005903|GO:0098588|GO:0043169|GO:0005783|GO:0044281|GO:0031982|GO:0005975|GO:0019904|GO:0048513|GO:0044255|GO:0007165|GO:0007154|GO:0006486|GO:0060322|GO:0031526|GO:0008202|GO:0007417|GO:0070085|GO:0016192|GO:0009416|GO:0044267|GO:0009059|GO:0006720|GO:0007399|GO:0031410|GO:0009100|GO:0007602|GO:0043412|GO:0017124|GO:0046872|GO:0006766|GO:1901137|GO:0034645|GO:0005773|GO:0009583|GO:0006066|GO:0016023|GO:0031988|GO:0042359|GO:0006464|GO:0043413|GO:0006897|GO:0009101|GO:0000323|GO:0007603|GO:0005765|GO:0005509|GO:0030139|GO:0009584|GO:0005764|GO:0006898|GO:0016101|GO:0001523 "signaling|extracellular region|membrane|cell|response to stimulus|organelle|cellular process|metabolic process|developmental process|macromolecular complex|binding|endomembrane system|cell proliferation|intrinsic component of membrane|organelle membrane|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|regulation of cellular process|biosynthetic process|cellular response to stimulus|response to external stimulus|ion binding|cell projection|cell periphery|plasma membrane|protein binding|coated pit|detection of stimulus|apical part of cell|protein complex|membrane-bounded organelle|response to abiotic stimulus|organic substance metabolic process|receptor complex|brain development|vacuolar membrane|system development|organic cyclic compound metabolic process|cytoplasm|detection of abiotic stimulus|cellular biosynthetic process|cell projection membrane|multicellular organism development|intracellular membrane-bounded organelle|extracellular exosome|Golgi apparatus|response to radiation|transport|apical plasma membrane|integral component of membrane|forebrain development|endosome|lipid metabolic process|protein metabolic process|brush border|bounding membrane of organelle|cation binding|endoplasmic reticulum|small molecule metabolic process|vesicle|carbohydrate metabolic process|protein domain specific binding|animal organ development|cellular lipid metabolic process|signal transduction|cell communication|protein glycosylation|head development|brush border membrane|steroid metabolic process|central nervous system development|glycosylation|vesicle-mediated transport|response to light stimulus|cellular protein metabolic process|macromolecule biosynthetic process|isoprenoid metabolic process|nervous system development|cytoplasmic vesicle|glycoprotein metabolic process|phototransduction|macromolecule modification|SH3 domain binding|metal ion binding|vitamin metabolic process|carbohydrate derivative biosynthetic process|cellular macromolecule biosynthetic process|vacuole|detection of light stimulus|alcohol metabolic process|cytoplasmic, membrane-bounded vesicle|membrane-bounded vesicle|vitamin D metabolic process|cellular protein modification process|macromolecule glycosylation|endocytosis|glycoprotein biosynthetic process|lytic vacuole|phototransduction, visible light|lysosomal membrane|calcium ion binding|endocytic vesicle|detection of visible light|lysosome|receptor-mediated endocytosis|diterpenoid metabolic process|retinoid metabolic process" K06233 low density lipoprotein-related protein 2[-] hsa04918|hsa04340 Thyroid hormone synthesis - Homo sapiens (human)|Hedgehog signaling pathway - Homo sapiens (human) chr2:169983619-170219195 0.06993547 0.006200173 3.495644057 2.03E-05 0.00117896 UP ENSG00000166770 AC004696.2 ZNF667 antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:44321] - - - - - - chr19:56988619-57012035 2.321779895 1.019592274 1.187238864 2.06E-05 0.001192561 UP ENSG00000143882 ATP6V1C2 "ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 [Source:HGNC Symbol;Acc:HGNC:18264]" GO:0023052|GO:0005576|GO:0016020|GO:0005623|GO:0050896|GO:0003824|GO:0005215|GO:0043226|GO:0009987|GO:0032991|GO:0005488|GO:0031090|GO:0005622|GO:0043229|GO:0022857|GO:0016043|GO:0050794|GO:0051716|GO:0016787|GO:0005515|GO:0043234|GO:0043227|GO:0010033|GO:0010243|GO:0042592|GO:0016817|GO:0044403|GO:0055085|GO:0051701|GO:0022891|GO:0005774|GO:0045184|GO:0033178|GO:0005737|GO:0019725|GO:0008104|GO:0009966|GO:0043231|GO:0070062|GO:0046983|GO:0009725|GO:0009967|GO:0016469|GO:0006810|GO:0098588|GO:0031982|GO:0006996|GO:0007165|GO:0010646|GO:0007154|GO:0005829|GO:0016820|GO:0033180|GO:0015075|GO:0030177|GO:0006811|GO:0033176|GO:0071417|GO:0043434|GO:0015031|GO:1901652|GO:0032870|GO:0034220|GO:0048878|GO:0005773|GO:0007166|GO:0016818|GO:0030111|GO:0055082|GO:0071310|GO:0090382|GO:0006873|GO:0033572|GO:0015992|GO:0016055|GO:0032868|GO:0042626|GO:0050801|GO:0071375|GO:0008324|GO:1901653|GO:0000323|GO:0006812|GO:0098655|GO:0005765|GO:0015991|GO:0007167|GO:0016462|GO:0019829|GO:1902600|GO:0015672|GO:0032869|GO:0007169|GO:0005764|GO:0030003|GO:0017111|GO:0030001|GO:0022890|GO:0008286|GO:0055065|GO:0016887|GO:0000041|GO:0006875|GO:0008553|GO:0042623|GO:0055076|GO:0006826|GO:0015078|GO:0006879|GO:0055072 "signaling|extracellular region|membrane|cell|response to stimulus|catalytic activity|transporter activity|organelle|cellular process|macromolecular complex|binding|organelle membrane|intracellular|intracellular organelle|transmembrane transporter activity|cellular component organization|regulation of cellular process|cellular response to stimulus|hydrolase activity|protein binding|protein complex|membrane-bounded organelle|response to organic substance|response to organonitrogen compound|homeostatic process|hydrolase activity, acting on acid anhydrides|symbiosis, encompassing mutualism through parasitism|transmembrane transport|interaction with host|substrate-specific transmembrane transporter activity|vacuolar membrane|establishment of protein localization|proton-transporting two-sector ATPase complex, catalytic domain|cytoplasm|cellular homeostasis|protein localization|regulation of signal transduction|intracellular membrane-bounded organelle|extracellular exosome|protein dimerization activity|response to hormone|positive regulation of signal transduction|proton-transporting two-sector ATPase complex|transport|bounding membrane of organelle|vesicle|organelle organization|signal transduction|regulation of cell communication|cell communication|cytosol|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|proton-transporting V-type ATPase, V1 domain|ion transmembrane transporter activity|positive regulation of Wnt signaling pathway|ion transport|proton-transporting V-type ATPase complex|cellular response to organonitrogen compound|response to peptide hormone|protein transport|response to peptide|cellular response to hormone stimulus|ion transmembrane transport|chemical homeostasis|vacuole|cell surface receptor signaling pathway|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|regulation of Wnt signaling pathway|cellular chemical homeostasis|cellular response to organic substance|phagosome maturation|cellular ion homeostasis|transferrin transport|proton transport|Wnt signaling pathway|response to insulin|ATPase activity, coupled to transmembrane movement of substances|ion homeostasis|cellular response to peptide hormone stimulus|cation transmembrane transporter activity|cellular response to peptide|lytic vacuole|cation transport|cation transmembrane transport|lysosomal membrane|ATP hydrolysis coupled proton transport|enzyme linked receptor protein signaling pathway|pyrophosphatase activity|cation-transporting ATPase activity|hydrogen ion transmembrane transport|monovalent inorganic cation transport|cellular response to insulin stimulus|transmembrane receptor protein tyrosine kinase signaling pathway|lysosome|cellular cation homeostasis|nucleoside-triphosphatase activity|metal ion transport|inorganic cation transmembrane transporter activity|insulin receptor signaling pathway|metal ion homeostasis|ATPase activity|transition metal ion transport|cellular metal ion homeostasis|hydrogen-exporting ATPase activity, phosphorylative mechanism|ATPase activity, coupled|transition metal ion homeostasis|iron ion transport|hydrogen ion transmembrane transporter activity|cellular iron ion homeostasis|iron ion homeostasis" K02148 V-type H+-transporting ATPase subunit C[-] hsa01100|hsa04145|hsa00190|hsa05323|hsa05120|hsa04721|hsa05110|hsa04966 Metabolic pathways - Homo sapiens (human)|Phagosome - Homo sapiens (human)|Oxidative phosphorylation - Homo sapiens (human)|Rheumatoid arthritis - Homo sapiens (human)|Epithelial cell signaling in Helicobacter pylori infection - Homo sapiens (human)|Synaptic vesicle cycle - Homo sapiens (human)|Vibrio cholerae infection - Homo sapiens (human)|Collecting duct acid secretion - Homo sapiens (human) chr2:10861775-10925236 5.11946314 2.14482866 1.255130125 2.52E-05 0.001413228 UP ENSG00000117425 PTCH2 patched 2 [Source:HGNC Symbol;Acc:HGNC:9586] - - K11101 patched 2[-] hsa05200|hsa05217|hsa04340 Pathways in cancer - Homo sapiens (human)|Basal cell carcinoma - Homo sapiens (human)|Hedgehog signaling pathway - Homo sapiens (human) chr1:45285516-45308735 3.912940201 1.786778142 1.130892552 2.53E-05 0.001414647 UP ENSG00000153446 C16orf89 chromosome 16 open reading frame 89 [Source:HGNC Symbol;Acc:HGNC:28687] GO:0005576|GO:0016020|GO:0005623|GO:0043226|GO:0005488|GO:0005622|GO:0005515|GO:0043227|GO:0005737|GO:0070062|GO:0046983|GO:0042802|GO:0031982|GO:0005829|GO:0042803 extracellular region|membrane|cell|organelle|binding|intracellular|protein binding|membrane-bounded organelle|cytoplasm|extracellular exosome|protein dimerization activity|identical protein binding|vesicle|cytosol|protein homodimerization activity - - - - chr16:5094123-5116111 0.571406188 0.172914792 1.724455369 2.68E-05 0.001479888 UP ENSG00000169884 WNT10B wingless-type MMTV integration site family member 10B [Source:HGNC Symbol;Acc:HGNC:12775] - - K01357 "wingless-type MMTV integration site family, member 10[-]" hsa05200|hsa05166|hsa05205|hsa04390|hsa04310|hsa04550|hsa04916|hsa05217|hsa04340 Pathways in cancer - Homo sapiens (human)|HTLV-I infection - Homo sapiens (human)|Proteoglycans in cancer - Homo sapiens (human)|Hippo signaling pathway - Homo sapiens (human)|Wnt signaling pathway - Homo sapiens (human)|Signaling pathways regulating pluripotency of stem cells - Homo sapiens (human)|Melanogenesis - Homo sapiens (human)|Basal cell carcinoma - Homo sapiens (human)|Hedgehog signaling pathway - Homo sapiens (human) chr12:49359123-49365546 1.28263278 0.442660011 1.534837227 2.70E-05 0.001479888 UP ENSG00000228278 ORM2 orosomucoid 2 [Source:HGNC Symbol;Acc:HGNC:8499] - - - - - - chr9:117092149-117095532 0.175200909 0.024276059 2.851404115 2.74E-05 0.001485593 UP ENSG00000162913 C1orf145 chromosome 1 open reading frame 145 [Source:HGNC Symbol;Acc:HGNC:32047] - - - - - - chr1:228391207-228401361 2.377243464 1.142582623 1.056991169 2.93E-05 0.001551433 UP ENSG00000232527 RP11-14N7.2 - - - - - - - chr1:148928322-148951595 8.105748091 3.936798392 1.041922508 3.61E-05 0.001811163 UP ENSG00000027869 SH2D2A SH2 domain containing 2A [Source:HGNC Symbol;Acc:HGNC:10821] - - K08273 SH2 domain protein 2A[-] hsa04370 VEGF signaling pathway - Homo sapiens (human) chr1:156776035-156786654 1.954343865 0.811706049 1.26765506 3.90E-05 0.001912661 UP ENSG00000205696 ADARB2-AS1 ADARB2 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:23299] - - - - - - chr10:1568832-1599179 1.196385233 0.398081986 1.587544516 4.91E-05 0.002263859 UP ENSG00000168309 FAM107A family with sequence similarity 107 member A [Source:HGNC Symbol;Acc:HGNC:30827] - - - - - - chr3:58549844-58613337 17.07499293 8.238364618 1.051455097 5.01E-05 0.00229632 UP ENSG00000170703 TTLL6 tubulin tyrosine ligase like 6 [Source:HGNC Symbol;Acc:HGNC:26664] GO:0005623|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0005622|GO:0043229|GO:0044237|GO:0016043|GO:0050794|GO:0005929|GO:0042995|GO:0016874|GO:0005515|GO:0071704|GO:0008092|GO:0051272|GO:0005737|GO:0032886|GO:0007017|GO:0006928|GO:0036064|GO:0019538|GO:0051270|GO:0006996|GO:0007010|GO:0051013|GO:0060632|GO:0005815|GO:0044267|GO:0003353|GO:0043412|GO:0015631|GO:0000226|GO:0005856|GO:0007018|GO:0001578|GO:0006464|GO:0003341|GO:0015630|GO:0018193|GO:0018095 cell|catalytic activity|organelle|cellular process|metabolic process|binding|intracellular|intracellular organelle|cellular metabolic process|cellular component organization|regulation of cellular process|cilium|cell projection|ligase activity|protein binding|organic substance metabolic process|cytoskeletal protein binding|positive regulation of cellular component movement|cytoplasm|regulation of microtubule-based process|microtubule-based process|movement of cell or subcellular component|ciliary basal body|protein metabolic process|regulation of cellular component movement|organelle organization|cytoskeleton organization|microtubule severing|regulation of microtubule-based movement|microtubule organizing center|cellular protein metabolic process|positive regulation of cilium movement|macromolecule modification|tubulin binding|microtubule cytoskeleton organization|cytoskeleton|microtubule-based movement|microtubule bundle formation|cellular protein modification process|cilium movement|microtubule cytoskeleton|peptidyl-amino acid modification|protein polyglutamylation - - - - chr17:46839597-46894576 0.195733736 0.07747761 1.337041068 5.68E-05 0.002508232 UP ENSG00000232973 CYP1B1-AS1 CYP1B1 antisense RNA 1 [Source:HGNC Symbol;Acc:HGNC:28543] - - - - - - chr2:38302791-38408997 0.666263951 0.277911152 1.26147011 5.81E-05 0.002545778 UP ENSG00000162631 NTNG1 netrin G1 [Source:HGNC Symbol;Acc:HGNC:23319] - - K07522 netrin-G1[-] hsa04360|hsa04514 Axon guidance - Homo sapiens (human)|Cell adhesion molecules (CAMs) - Homo sapiens (human) chr1:107682629-108026080 4.378862327 1.599012922 1.453374494 5.85E-05 0.002560822 UP ENSG00000178882 FAM101A family with sequence similarity 101 member A [Source:HGNC Symbol;Acc:HGNC:27051] GO:0005623|GO:0043226|GO:0009987|GO:0032502|GO:0005488|GO:0005622|GO:0043229|GO:0048856|GO:0016043|GO:0050794|GO:0005515|GO:0009653|GO:0050793|GO:0048523|GO:1903011|GO:0008092|GO:0045596|GO:0030278|GO:0048468|GO:0009888|GO:0030029|GO:0060348|GO:0048731|GO:0005737|GO:0045595|GO:0001503|GO:0048869|GO:0070168|GO:0007275|GO:0061037|GO:0021700|GO:0009887|GO:0030279|GO:0048513|GO:0006996|GO:0031214|GO:0007010|GO:0002063|GO:0030502|GO:0030154|GO:0043931|GO:1900158|GO:0070977|GO:0032331|GO:0031005|GO:0032330|GO:0061448|GO:0030036|GO:0001501|GO:0048705|GO:0030500|GO:0061035|GO:0030282|GO:0032432|GO:0051216|GO:0010721|GO:0005856|GO:0061182|GO:0015629|GO:0035630|GO:0007015|GO:0002062|GO:0061572 cell|organelle|cellular process|developmental process|binding|intracellular|intracellular organelle|anatomical structure development|cellular component organization|regulation of cellular process|protein binding|anatomical structure morphogenesis|regulation of developmental process|negative regulation of cellular process|negative regulation of bone development|cytoskeletal protein binding|negative regulation of cell differentiation|regulation of ossification|cell development|tissue development|actin filament-based process|bone development|system development|cytoplasm|regulation of cell differentiation|ossification|cellular developmental process|negative regulation of biomineral tissue development|multicellular organism development|negative regulation of cartilage development|developmental maturation|organ morphogenesis|negative regulation of ossification|animal organ development|organelle organization|biomineral tissue development|cytoskeleton organization|chondrocyte development|negative regulation of bone mineralization|cell differentiation|ossification involved in bone maturation|negative regulation of bone mineralization involved in bone maturation|bone maturation|negative regulation of chondrocyte differentiation|filamin binding|regulation of chondrocyte differentiation|connective tissue development|actin cytoskeleton organization|skeletal system development|skeletal system morphogenesis|regulation of bone mineralization|regulation of cartilage development|bone mineralization|actin filament bundle|cartilage development|negative regulation of cell development|cytoskeleton|negative regulation of chondrocyte development|actin cytoskeleton|bone mineralization involved in bone maturation|actin filament organization|chondrocyte differentiation|actin filament bundle organization - - - - chr12:124773710-124800570 0.745356501 0.312280066 1.255090146 5.98E-05 0.002601685 UP ENSG00000183092 BEGAIN brain enriched guanylate kinase associated [Source:HGNC Symbol;Acc:HGNC:24163] GO:0016020|GO:0005623|GO:0003824|GO:0009987|GO:0008152|GO:0005488|GO:0005622|GO:0044237|GO:0005515|GO:0016740|GO:0005737|GO:0016772|GO:0006796|GO:0016301|GO:0016310 "membrane|cell|catalytic activity|cellular process|metabolic process|binding|intracellular|cellular metabolic process|protein binding|transferase activity|cytoplasm|transferase activity, transferring phosphorus-containing groups|phosphate-containing compound metabolic process|kinase activity|phosphorylation" - - - - chr14:101003486-101053750 1.205602744 0.310186178 1.958548298 6.98E-05 0.002922291 UP ENSG00000234292 RP11-213H15.1 - - - - - - - chr5:90575914-90576959 2.285969686 0.916764629 1.318182985 7.35E-05 0.003055474 UP ENSG00000187634 SAMD11 sterile alpha motif domain containing 11 [Source:HGNC Symbol;Acc:HGNC:28706] - - - - - - chr1:860260-879955 1.409204059 0.495211544 1.508763684 7.38E-05 0.003060785 UP ENSG00000105650 PDE4C phosphodiesterase 4C [Source:HGNC Symbol;Acc:HGNC:8782] - - K13293 cAMP-specific phosphodiesterase 4[3.1.4.53] hsa04024|hsa00230|hsa05032 cAMP signaling pathway - Homo sapiens (human)|Purine metabolism - Homo sapiens (human)|Morphine addiction - Homo sapiens (human) chr19:18318771-18366229 3.351150274 1.361711787 1.299235 7.50E-05 0.003094173 UP ENSG00000188282 RUFY4 RUN and FYVE domain containing 4 [Source:HGNC Symbol;Acc:HGNC:24804] GO:0005488|GO:0043167|GO:0005515|GO:0043169|GO:0046872 binding|ion binding|protein binding|cation binding|metal ion binding - - - - chr2:218933738-218955303 1.872053095 0.832756101 1.16865543 7.50E-05 0.003094173 UP ENSG00000144644 GADL1 glutamate decarboxylase like 1 [Source:HGNC Symbol;Acc:HGNC:27949] - - K18966 sulfinoalanine decarboxylase / aspartate 1-decarboxylase[4.1.1.11] hsa01100|hsa00410|hsa00770|hsa00430 Metabolic pathways - Homo sapiens (human)|beta-Alanine metabolism - Homo sapiens (human)|Pantothenate and CoA biosynthesis - Homo sapiens (human)|Taurine and hypotaurine metabolism - Homo sapiens (human) chr3:30767692-30936257 0.135712159 0.035855602 1.920279551 7.59E-05 0.003126371 UP ENSG00000127585 FBXL16 F-box and leucine-rich repeat protein 16 [Source:HGNC Symbol;Acc:HGNC:14150] GO:0005623|GO:0005488|GO:0005622|GO:0005515|GO:0005737 cell|binding|intracellular|protein binding|cytoplasm - - - - chr16:742500-755829 2.018236706 0.974805992 1.049908364 7.86E-05 0.003205749 UP ENSG00000133048 CHI3L1 chitinase 3 like 1 [Source:HGNC Symbol;Acc:HGNC:1932] GO:0023052|GO:0005576|GO:0031012|GO:0005623|GO:0005198|GO:0050896|GO:0002376|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0012505|GO:0009893|GO:0006955|GO:0009056|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0030246|GO:0050794|GO:0051716|GO:0009605|GO:0006950|GO:0006807|GO:0048646|GO:0016787|GO:0097367|GO:0009653|GO:0005201|GO:0019222|GO:0050793|GO:0005615|GO:0043227|GO:0005578|GO:0009628|GO:0071704|GO:0010033|GO:0006952|GO:0001816|GO:0009888|GO:0001568|GO:0045184|GO:0016798|GO:0035295|GO:0048731|GO:0008061|GO:0005737|GO:0030323|GO:0008104|GO:0043085|GO:0007275|GO:0009966|GO:0043231|GO:0070062|GO:0009967|GO:0050790|GO:0006810|GO:0032940|GO:0008219|GO:0031325|GO:0019538|GO:0048514|GO:0009612|GO:0005783|GO:0031323|GO:0031982|GO:0005975|GO:0048513|GO:0030324|GO:0007165|GO:0023014|GO:0010646|GO:0007154|GO:0001525|GO:0009306|GO:0006040|GO:0046903|GO:0050663|GO:0004553|GO:0048471|GO:0044267|GO:0045766|GO:0034097|GO:0032270|GO:0061448|GO:0051174|GO:0072358|GO:0000165|GO:0001501|GO:0051247|GO:0043412|GO:0051347|GO:0015031|GO:0051216|GO:0051246|GO:0035556|GO:0060541|GO:0045765|GO:1902533|GO:0006796|GO:0001944|GO:0072359|GO:0032637|GO:0012501|GO:0006954|GO:0032268|GO:1901342|GO:0071310|GO:0043549|GO:1901222|GO:1901224|GO:0033674|GO:0006030|GO:0051896|GO:0006464|GO:0072606|GO:0070555|GO:0043491|GO:0051897|GO:0016310|GO:0031401|GO:0043408|GO:0006915|GO:0034612|GO:0071345|GO:0070371|GO:0004568|GO:0038061|GO:0070741|GO:0043410|GO:0045860|GO:0001932|GO:0071356|GO:0071347|GO:0007250|GO:0018193|GO:0001934|GO:0006032|GO:0070374|GO:0042327|GO:0042325|GO:0006468|GO:0045859|GO:0070372|GO:0071902|GO:0018107|GO:0010800|GO:0032147 "signaling|extracellular region|extracellular matrix|cell|structural molecule activity|response to stimulus|immune system process|catalytic activity|organelle|cellular process|metabolic process|developmental process|binding|endomembrane system|positive regulation of metabolic process|immune response|catabolic process|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|carbohydrate binding|regulation of cellular process|cellular response to stimulus|response to external stimulus|response to stress|nitrogen compound metabolic process|anatomical structure formation involved in morphogenesis|hydrolase activity|carbohydrate derivative binding|anatomical structure morphogenesis|extracellular matrix structural constituent|regulation of metabolic process|regulation of developmental process|extracellular space|membrane-bounded organelle|proteinaceous extracellular matrix|response to abiotic stimulus|organic substance metabolic process|response to organic substance|defense response|cytokine production|tissue development|blood vessel development|establishment of protein localization|hydrolase activity, acting on glycosyl bonds|tube development|system development|chitin binding|cytoplasm|respiratory tube development|protein localization|positive regulation of catalytic activity|multicellular organism development|regulation of signal transduction|intracellular membrane-bounded organelle|extracellular exosome|positive regulation of signal transduction|regulation of catalytic activity|transport|secretion by cell|cell death|positive regulation of cellular metabolic process|protein metabolic process|blood vessel morphogenesis|response to mechanical stimulus|endoplasmic reticulum|regulation of cellular metabolic process|vesicle|carbohydrate metabolic process|animal organ development|lung development|signal transduction|signal transduction by protein phosphorylation|regulation of cell communication|cell communication|angiogenesis|protein secretion|amino sugar metabolic process|secretion|cytokine secretion|hydrolase activity, hydrolyzing O-glycosyl compounds|perinuclear region of cytoplasm|cellular protein metabolic process|positive regulation of angiogenesis|response to cytokine|positive regulation of cellular protein metabolic process|connective tissue development|regulation of phosphorus metabolic process|cardiovascular system development|MAPK cascade|skeletal system development|positive regulation of protein metabolic process|macromolecule modification|positive regulation of transferase activity|protein transport|cartilage development|regulation of protein metabolic process|intracellular signal transduction|respiratory system development|regulation of angiogenesis|positive regulation of intracellular signal transduction|phosphate-containing compound metabolic process|vasculature development|circulatory system development|interleukin-8 production|programmed cell death|inflammatory response|regulation of cellular protein metabolic process|regulation of vasculature development|cellular response to organic substance|regulation of kinase activity|regulation of NIK/NF-kappaB signaling|positive regulation of NIK/NF-kappaB signaling|positive regulation of kinase activity|chitin metabolic process|regulation of protein kinase B signaling|cellular protein modification process|interleukin-8 secretion|response to interleukin-1|protein kinase B signaling|positive regulation of protein kinase B signaling|phosphorylation|positive regulation of protein modification process|regulation of MAPK cascade|apoptotic process|response to tumor necrosis factor|cellular response to cytokine stimulus|ERK1 and ERK2 cascade|chitinase activity|NIK/NF-kappaB signaling|response to interleukin-6|positive regulation of MAPK cascade|positive regulation of protein kinase activity|regulation of protein phosphorylation|cellular response to tumor necrosis factor|cellular response to interleukin-1|activation of NF-kappaB-inducing kinase activity|peptidyl-amino acid modification|positive regulation of protein phosphorylation|chitin catabolic process|positive regulation of ERK1 and ERK2 cascade|positive regulation of phosphorylation|regulation of phosphorylation|protein phosphorylation|regulation of protein kinase activity|regulation of ERK1 and ERK2 cascade|positive regulation of protein serine/threonine kinase activity|peptidyl-threonine phosphorylation|positive regulation of peptidyl-threonine phosphorylation|activation of protein kinase activity" - - - - chr1:203148059-203155877 21.15016555 5.811094648 1.863787098 0.000104 0.003947863 UP ENSG00000169427 KCNK9 "potassium channel, two pore domain subfamily K, member 9 [Source:HGNC Symbol;Acc:HGNC:6283]" - - K04919 potassium channel subfamily K member 9[-] hsa04925 Aldosterone synthesis and secretion - Homo sapiens (human) chr8:140624804-140715299 0.062961838 0.003148654 4.321670735 0.000105903 0.003996617 UP ENSG00000175183 CSRP2 cysteine and glycine rich protein 2 [Source:HGNC Symbol;Acc:HGNC:2470] GO:0005623|GO:0030054|GO:0043226|GO:0009987|GO:0032502|GO:0005488|GO:0005622|GO:0043229|GO:0048856|GO:0043167|GO:0005515|GO:0043227|GO:0030055|GO:0005912|GO:0005924|GO:0048869|GO:0007275|GO:0043231|GO:0061061|GO:0043169|GO:0005634|GO:0030154|GO:0042692|GO:0046872|GO:0005925|GO:0046914|GO:0045445|GO:0008270 cell|cell junction|organelle|cellular process|developmental process|binding|intracellular|intracellular organelle|anatomical structure development|ion binding|protein binding|membrane-bounded organelle|cell-substrate junction|adherens junction|cell-substrate adherens junction|cellular developmental process|multicellular organism development|intracellular membrane-bounded organelle|muscle structure development|cation binding|nucleus|cell differentiation|muscle cell differentiation|metal ion binding|focal adhesion|transition metal ion binding|myoblast differentiation|zinc ion binding - - - - chr12:77252495-77272840 152.5537421 58.55792737 1.381381173 0.000106252 0.004003927 UP ENSG00000005961 ITGA2B integrin subunit alpha 2b [Source:HGNC Symbol;Acc:HGNC:6138] GO:0023052|GO:0005576|GO:0040011|GO:0016020|GO:0005623|GO:0030054|GO:0050896|GO:0002376|GO:0043226|GO:0009987|GO:0032502|GO:0032991|GO:0005488|GO:0012505|GO:0048870|GO:0002684|GO:0031224|GO:0031090|GO:0040017|GO:0005622|GO:0043229|GO:0048856|GO:0016043|GO:0050794|GO:0051716|GO:0009605|GO:0043167|GO:0040012|GO:0006950|GO:0050900|GO:0007155|GO:0072562|GO:0071944|GO:0005886|GO:0005515|GO:0009986|GO:0009653|GO:0050840|GO:0043234|GO:0005615|GO:0043227|GO:0002682|GO:0030055|GO:0043235|GO:0016337|GO:0005912|GO:0030667|GO:0048468|GO:0030030|GO:2000145|GO:0043062|GO:0051272|GO:0048731|GO:0032403|GO:0005737|GO:0016477|GO:0005924|GO:0031226|GO:0048869|GO:0007275|GO:0043231|GO:0070062|GO:0031589|GO:0001775|GO:0009611|GO:0006928|GO:0006810|GO:0042802|GO:0032940|GO:0016021|GO:2000147|GO:0005887|GO:0012506|GO:0098588|GO:0051270|GO:0043169|GO:0002685|GO:0050878|GO:0006935|GO:0031982|GO:0007165|GO:0098609|GO:0007154|GO:0002687|GO:0009897|GO:0030141|GO:0030334|GO:0030168|GO:0030659|GO:0042060|GO:0006887|GO:0008305|GO:0031091|GO:0046903|GO:0016192|GO:0030154|GO:0048666|GO:0007399|GO:0000902|GO:0032990|GO:0031410|GO:0007160|GO:0030198|GO:0048858|GO:0000904|GO:0046872|GO:0031175|GO:0034109|GO:0007599|GO:0005925|GO:0031092|GO:0007166|GO:0030335|GO:0007596|GO:0016023|GO:0070051|GO:0031988|GO:0022008|GO:0007229|GO:0061564|GO:0045055|GO:0007411|GO:0048667|GO:0048812|GO:0070527|GO:0030182|GO:0007409|GO:0048699|GO:0002576 "signaling|extracellular region|locomotion|membrane|cell|cell junction|response to stimulus|immune system process|organelle|cellular process|developmental process|macromolecular complex|binding|endomembrane system|cell motility|positive regulation of immune system process|intrinsic component of membrane|organelle membrane|positive regulation of locomotion|intracellular|intracellular organelle|anatomical structure development|cellular component organization|regulation of cellular process|cellular response to stimulus|response to external stimulus|ion binding|regulation of locomotion|response to stress|leukocyte migration|cell adhesion|blood microparticle|cell periphery|plasma membrane|protein binding|cell surface|anatomical structure morphogenesis|extracellular matrix binding|protein complex|extracellular space|membrane-bounded organelle|regulation of immune system process|cell-substrate junction|receptor complex|single organismal cell-cell adhesion|adherens junction|secretory granule membrane|cell development|cell projection organization|regulation of cell motility|extracellular structure organization|positive regulation of cellular component movement|system development|protein complex binding|cytoplasm|cell migration|cell-substrate adherens junction|intrinsic component of plasma membrane|cellular developmental process|multicellular organism development|intracellular membrane-bounded organelle|extracellular exosome|cell-substrate adhesion|cell activation|response to wounding|movement of cell or subcellular component|transport|identical protein binding|secretion by cell|integral component of membrane|positive regulation of cell motility|integral component of plasma membrane|vesicle membrane|bounding membrane of organelle|regulation of cellular component movement|cation binding|regulation of leukocyte migration|regulation of body fluid levels|chemotaxis|vesicle|signal transduction|cell-cell adhesion|cell communication|positive regulation of leukocyte migration|external side of plasma membrane|secretory granule|regulation of cell migration|platelet activation|cytoplasmic vesicle membrane|wound healing|exocytosis|integrin complex|platelet alpha granule|secretion|vesicle-mediated transport|cell differentiation|neuron development|nervous system development|cell morphogenesis|cell part morphogenesis|cytoplasmic vesicle|cell-matrix adhesion|extracellular matrix organization|cell projection morphogenesis|cell morphogenesis involved in differentiation|metal ion binding|neuron projection development|homotypic cell-cell adhesion|hemostasis|focal adhesion|platelet alpha granule membrane|cell surface receptor signaling pathway|positive regulation of cell migration|blood coagulation|cytoplasmic, membrane-bounded vesicle|fibrinogen binding|membrane-bounded vesicle|neurogenesis|integrin-mediated signaling pathway|axon development|regulated exocytosis|axon guidance|cell morphogenesis involved in neuron differentiation|neuron projection morphogenesis|platelet aggregation|neuron differentiation|axonogenesis|generation of neurons|platelet degranulation" K06476 integrin alpha 2B[-] hsa05200|hsa04151|hsa04810|hsa04015|hsa04510|hsa04611|hsa05414|hsa04640|hsa05222|hsa05410|hsa04512|hsa05412 Pathways in cancer - Homo sapiens (human)|PI3K-Akt signaling pathway - Homo sapiens (human)|Regulation of actin cytoskeleton - Homo sapiens (human)|Rap1 signaling pathway - Homo sapiens (human)|Focal adhesion - Homo sapiens (human)|Platelet activation - Homo sapiens (human)|Dilated cardiomyopathy - Homo sapiens (human)|Hematopoietic cell lineage - Homo sapiens (human)|Small cell lung cancer - Homo sapiens (human)|Hypertrophic cardiomyopathy (HCM) - Homo sapiens (human)|ECM-receptor interaction - Homo sapiens (human)|Arrhythmogenic right ventricular cardiomyopathy (ARVC) - Homo sapiens (human) chr17:42449548-42466873 0.648352491 0.279620427 1.213308622 0.000106701 0.004008771 UP ENSG00000133067 LGR6 leucine-rich repeat containing G protein-coupled receptor 6 [Source:HGNC Symbol;Acc:HGNC:19719] GO:0023052|GO:0040011|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0043226|GO:0009987|GO:0005488|GO:0012505|GO:0048870|GO:0038023|GO:0031224|GO:0031090|GO:0040017|GO:0005622|GO:0043229|GO:0050794|GO:0051716|GO:0040012|GO:0071944|GO:0005886|GO:0005515|GO:0043227|GO:0004872|GO:0004888|GO:2000145|GO:0051272|GO:0005737|GO:0016477|GO:0031226|GO:0009966|GO:0043231|GO:0005794|GO:0009967|GO:0006928|GO:0016021|GO:2000147|GO:0005887|GO:0098588|GO:0051270|GO:0031982|GO:0007165|GO:0010646|GO:0007154|GO:0030334|GO:0005802|GO:0005634|GO:0000139|GO:0030177|GO:0005654|GO:0007186|GO:0031981|GO:0004930|GO:0007166|GO:0030111|GO:0030335|GO:0060828|GO:0016055|GO:0090263|GO:0032588|GO:0060070 signaling|locomotion|membrane|cell|response to stimulus|signal transducer activity|organelle|cellular process|binding|endomembrane system|cell motility|signaling receptor activity|intrinsic component of membrane|organelle membrane|positive regulation of locomotion|intracellular|intracellular organelle|regulation of cellular process|cellular response to stimulus|regulation of locomotion|cell periphery|plasma membrane|protein binding|membrane-bounded organelle|receptor activity|transmembrane signaling receptor activity|regulation of cell motility|positive regulation of cellular component movement|cytoplasm|cell migration|intrinsic component of plasma membrane|regulation of signal transduction|intracellular membrane-bounded organelle|Golgi apparatus|positive regulation of signal transduction|movement of cell or subcellular component|integral component of membrane|positive regulation of cell motility|integral component of plasma membrane|bounding membrane of organelle|regulation of cellular component movement|vesicle|signal transduction|regulation of cell communication|cell communication|regulation of cell migration|trans-Golgi network|nucleus|Golgi membrane|positive regulation of Wnt signaling pathway|nucleoplasm|G-protein coupled receptor signaling pathway|nuclear lumen|G-protein coupled receptor activity|cell surface receptor signaling pathway|regulation of Wnt signaling pathway|positive regulation of cell migration|regulation of canonical Wnt signaling pathway|Wnt signaling pathway|positive regulation of canonical Wnt signaling pathway|trans-Golgi network membrane|canonical Wnt signaling pathway - - - - chr1:202163029-202288909 7.729596254 3.116603792 1.310418299 0.000112799 0.004147684 UP ENSG00000101197 BIRC7 baculoviral IAP repeat containing 7 [Source:HGNC Symbol;Acc:HGNC:13702] GO:0023052|GO:0005623|GO:0050896|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0012505|GO:0009893|GO:0008283|GO:0005622|GO:0043229|GO:0044237|GO:0050794|GO:0051716|GO:0043167|GO:0006950|GO:0016874|GO:0030234|GO:0005515|GO:0019222|GO:0016740|GO:0009892|GO:0048523|GO:0043227|GO:0071704|GO:0044092|GO:0060548|GO:0033554|GO:0043086|GO:0005737|GO:0043085|GO:0009966|GO:0043231|GO:0005794|GO:0019899|GO:0009967|GO:0019787|GO:0050790|GO:0008219|GO:0031325|GO:0019538|GO:0031324|GO:0042127|GO:0043169|GO:0031323|GO:0004857|GO:0007165|GO:0023014|GO:0010646|GO:0007154|GO:0010941|GO:0051248|GO:0032269|GO:0010468|GO:0005634|GO:0051604|GO:0044267|GO:0004842|GO:0043027|GO:0031098|GO:0010629|GO:0032270|GO:0051174|GO:0030414|GO:0051346|GO:0000165|GO:0051247|GO:0043067|GO:0043412|GO:0051347|GO:0046872|GO:0043069|GO:0006508|GO:0051246|GO:0035556|GO:1902533|GO:0010467|GO:0006796|GO:0012501|GO:0032268|GO:0043549|GO:0033674|GO:0051403|GO:0006464|GO:0052547|GO:0030162|GO:0070304|GO:0032872|GO:0046914|GO:0016310|GO:0031401|GO:0043408|GO:0006915|GO:0042981|GO:0043066|GO:0004866|GO:0010466|GO:0045861|GO:0016485|GO:0043410|GO:0043406|GO:0032874|GO:0045860|GO:0046328|GO:0001932|GO:0007254|GO:0001934|GO:0043154|GO:0043281|GO:0008270|GO:0010951|GO:0042327|GO:0042325|GO:0004869|GO:0010955|GO:0006468|GO:0052548|GO:0043405|GO:0045859|GO:0070613|GO:2000117|GO:0071902|GO:0046330|GO:0000187|GO:0070228|GO:0007257|GO:0032446|GO:0043506|GO:0032147|GO:0043507|GO:1990001|GO:2000116|GO:0070247|GO:0016567 signaling|cell|response to stimulus|catalytic activity|organelle|cellular process|metabolic process|binding|endomembrane system|positive regulation of metabolic process|cell proliferation|intracellular|intracellular organelle|cellular metabolic process|regulation of cellular process|cellular response to stimulus|ion binding|response to stress|ligase activity|enzyme regulator activity|protein binding|regulation of metabolic process|transferase activity|negative regulation of metabolic process|negative regulation of cellular process|membrane-bounded organelle|organic substance metabolic process|negative regulation of molecular function|negative regulation of cell death|cellular response to stress|negative regulation of catalytic activity|cytoplasm|positive regulation of catalytic activity|regulation of signal transduction|intracellular membrane-bounded organelle|Golgi apparatus|enzyme binding|positive regulation of signal transduction|ubiquitin-like protein transferase activity|regulation of catalytic activity|cell death|positive regulation of cellular metabolic process|protein metabolic process|negative regulation of cellular metabolic process|regulation of cell proliferation|cation binding|regulation of cellular metabolic process|enzyme inhibitor activity|signal transduction|signal transduction by protein phosphorylation|regulation of cell communication|cell communication|regulation of cell death|negative regulation of protein metabolic process|negative regulation of cellular protein metabolic process|regulation of gene expression|nucleus|protein maturation|cellular protein metabolic process|ubiquitin-protein transferase activity|cysteine-type endopeptidase inhibitor activity involved in apoptotic process|stress-activated protein kinase signaling cascade|negative regulation of gene expression|positive regulation of cellular protein metabolic process|regulation of phosphorus metabolic process|peptidase inhibitor activity|negative regulation of hydrolase activity|MAPK cascade|positive regulation of protein metabolic process|regulation of programmed cell death|macromolecule modification|positive regulation of transferase activity|metal ion binding|negative regulation of programmed cell death|proteolysis|regulation of protein metabolic process|intracellular signal transduction|positive regulation of intracellular signal transduction|gene expression|phosphate-containing compound metabolic process|programmed cell death|regulation of cellular protein metabolic process|regulation of kinase activity|positive regulation of kinase activity|stress-activated MAPK cascade|cellular protein modification process|regulation of peptidase activity|regulation of proteolysis|positive regulation of stress-activated protein kinase signaling cascade|regulation of stress-activated MAPK cascade|transition metal ion binding|phosphorylation|positive regulation of protein modification process|regulation of MAPK cascade|apoptotic process|regulation of apoptotic process|negative regulation of apoptotic process|endopeptidase inhibitor activity|negative regulation of peptidase activity|negative regulation of proteolysis|protein processing|positive regulation of MAPK cascade|positive regulation of MAP kinase activity|positive regulation of stress-activated MAPK cascade|positive regulation of protein kinase activity|regulation of JNK cascade|regulation of protein phosphorylation|JNK cascade|positive regulation of protein phosphorylation|negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|regulation of cysteine-type endopeptidase activity involved in apoptotic process|zinc ion binding|negative regulation of endopeptidase activity|positive regulation of phosphorylation|regulation of phosphorylation|cysteine-type endopeptidase inhibitor activity|negative regulation of protein processing|protein phosphorylation|regulation of endopeptidase activity|regulation of MAP kinase activity|regulation of protein kinase activity|regulation of protein processing|negative regulation of cysteine-type endopeptidase activity|positive regulation of protein serine/threonine kinase activity|positive regulation of JNK cascade|activation of MAPK activity|regulation of lymphocyte apoptotic process|activation of JUN kinase activity|protein modification by small protein conjugation|regulation of JUN kinase activity|activation of protein kinase activity|positive regulation of JUN kinase activity|inhibition of cysteine-type endopeptidase activity involved in apoptotic process|regulation of cysteine-type endopeptidase activity|regulation of natural killer cell apoptotic process|protein ubiquitination K16061 baculoviral IAP repeat-containing protein 7/8[-] hsa05200|hsa04120|hsa05145|hsa05222 Pathways in cancer - Homo sapiens (human)|Ubiquitin mediated proteolysis - Homo sapiens (human)|Toxoplasmosis - Homo sapiens (human)|Small cell lung cancer - Homo sapiens (human) chr20:61867235-61871859 1.448204269 0.497875383 1.54040852 0.000135177 0.004811542 UP ENSG00000239335 RP11-745O10.2 LLPH antisense RNA 1 (head to head) [Source:HGNC Symbol;Acc:HGNC:50493] - - - - - - chr12:66524531-66528229 1.030693262 0.327504422 1.654028753 0.000140587 0.004937391 UP ENSG00000113100 CDH9 "cadherin 9, type 2 (T1-cadherin) [Source:HGNC Symbol;Acc:HGNC:1768]" GO:0016020|GO:0005623|GO:0009987|GO:0005488|GO:0031224|GO:0016043|GO:0043167|GO:0007155|GO:0071944|GO:0005886|GO:0016337|GO:0034330|GO:0022607|GO:0016021|GO:0043169|GO:0098609|GO:0098742|GO:0046872|GO:0034329|GO:0045216|GO:0007156|GO:0034332|GO:0005509 membrane|cell|cellular process|binding|intrinsic component of membrane|cellular component organization|ion binding|cell adhesion|cell periphery|plasma membrane|single organismal cell-cell adhesion|cell junction organization|cellular component assembly|integral component of membrane|cation binding|cell-cell adhesion|cell-cell adhesion via plasma-membrane adhesion molecules|metal ion binding|cell junction assembly|cell-cell junction organization|homophilic cell adhesion via plasma membrane adhesion molecules|adherens junction organization|calcium ion binding - - - - chr5:26880709-27121257 0.087575829 0.004536051 4.271024075 0.000143015 0.004988713 UP ENSG00000169418 NPR1 natriuretic peptide receptor 1 [Source:HGNC Symbol;Acc:HGNC:7943] GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0003824|GO:0040007|GO:0009987|GO:0008152|GO:0032502|GO:0032991|GO:0005488|GO:0016829|GO:0009893|GO:0038023|GO:0042562|GO:0008283|GO:0040008|GO:0031224|GO:0048856|GO:0044237|GO:0051050|GO:0016043|GO:0045926|GO:0050794|GO:0009058|GO:0051716|GO:0043167|GO:0006807|GO:0097159|GO:0048646|GO:0071944|GO:0097367|GO:0005886|GO:0005515|GO:0009653|GO:0019222|GO:0050793|GO:0016740|GO:0048523|GO:0043234|GO:0016049|GO:0036094|GO:0004872|GO:0071704|GO:0017046|GO:0043235|GO:0042592|GO:0051128|GO:0042277|GO:0004888|GO:0008285|GO:0035815|GO:0001568|GO:0048731|GO:1901360|GO:0007588|GO:0044249|GO:2000021|GO:0031226|GO:0003013|GO:0006139|GO:0008217|GO:0007275|GO:0034641|GO:0019899|GO:0006810|GO:0006725|GO:0016021|GO:0005887|GO:0004383|GO:0055086|GO:0031325|GO:0000166|GO:0016772|GO:0019538|GO:0043114|GO:0003014|GO:0019637|GO:0048514|GO:0042127|GO:0050878|GO:0046483|GO:0044281|GO:0031323|GO:0016849|GO:0001558|GO:0007165|GO:0051047|GO:0007154|GO:0001882|GO:0001525|GO:0030308|GO:0006584|GO:0018958|GO:0031328|GO:0019693|GO:0048660|GO:0046903|GO:0035150|GO:0035813|GO:0042417|GO:0032549|GO:0016941|GO:0035639|GO:0016525|GO:0044267|GO:0017076|GO:0048659|GO:0051174|GO:0007589|GO:0072358|GO:0007186|GO:0044062|GO:0043412|GO:1901137|GO:0035556|GO:0001883|GO:0045765|GO:0019900|GO:0008015|GO:0016773|GO:0006796|GO:0048878|GO:0008528|GO:0004930|GO:0051046|GO:0001944|GO:0016301|GO:0072359|GO:0007166|GO:0048662|GO:1901342|GO:0006163|GO:0009117|GO:0004672|GO:0005525|GO:0006464|GO:0009259|GO:0009165|GO:0009712|GO:0046390|GO:0016310|GO:0050801|GO:0050880|GO:0019001|GO:0019901|GO:0035810|GO:0005524|GO:0042312|GO:0007167|GO:0007168|GO:0009187|GO:0042311|GO:0006164|GO:0009190|GO:0030801|GO:0004713|GO:0006468|GO:0046068|GO:0030825|GO:0030823|GO:0009152|GO:0055065|GO:0030826|GO:0030828|GO:0006182|GO:0055078 "signaling|membrane|cell|response to stimulus|signal transducer activity|catalytic activity|growth|cellular process|metabolic process|developmental process|macromolecular complex|binding|lyase activity|positive regulation of metabolic process|signaling receptor activity|hormone binding|cell proliferation|regulation of growth|intrinsic component of membrane|anatomical structure development|cellular metabolic process|positive regulation of transport|cellular component organization|negative regulation of growth|regulation of cellular process|biosynthetic process|cellular response to stimulus|ion binding|nitrogen compound metabolic process|organic cyclic compound binding|anatomical structure formation involved in morphogenesis|cell periphery|carbohydrate derivative binding|plasma membrane|protein binding|anatomical structure morphogenesis|regulation of metabolic process|regulation of developmental process|transferase activity|negative regulation of cellular process|protein complex|cell growth|small molecule binding|receptor activity|organic substance metabolic process|peptide hormone binding|receptor complex|homeostatic process|regulation of cellular component organization|peptide binding|transmembrane signaling receptor activity|negative regulation of cell proliferation|positive regulation of renal sodium excretion|blood vessel development|system development|organic cyclic compound metabolic process|excretion|cellular biosynthetic process|regulation of ion homeostasis|intrinsic component of plasma membrane|circulatory system process|nucleobase-containing compound metabolic process|regulation of blood pressure|multicellular organism development|cellular nitrogen compound metabolic process|enzyme binding|transport|cellular aromatic compound metabolic process|integral component of membrane|integral component of plasma membrane|guanylate cyclase activity|nucleobase-containing small molecule metabolic process|positive regulation of cellular metabolic process|nucleotide binding|transferase activity, transferring phosphorus-containing groups|protein metabolic process|regulation of vascular permeability|renal system process|organophosphate metabolic process|blood vessel morphogenesis|regulation of cell proliferation|regulation of body fluid levels|heterocycle metabolic process|small molecule metabolic process|regulation of cellular metabolic process|phosphorus-oxygen lyase activity|regulation of cell growth|signal transduction|positive regulation of secretion|cell communication|nucleoside binding|angiogenesis|negative regulation of cell growth|catecholamine metabolic process|phenol-containing compound metabolic process|positive regulation of cellular biosynthetic process|ribose phosphate metabolic process|regulation of smooth muscle cell proliferation|secretion|regulation of tube size|regulation of renal sodium excretion|dopamine metabolic process|ribonucleoside binding|natriuretic peptide receptor activity|purine ribonucleoside triphosphate binding|negative regulation of angiogenesis|cellular protein metabolic process|purine nucleotide binding|smooth muscle cell proliferation|regulation of phosphorus metabolic process|body fluid secretion|cardiovascular system development|G-protein coupled receptor signaling pathway|regulation of excretion|macromolecule modification|carbohydrate derivative biosynthetic process|intracellular signal transduction|purine nucleoside binding|regulation of angiogenesis|kinase binding|blood circulation|phosphotransferase activity, alcohol group as acceptor|phosphate-containing compound metabolic process|chemical homeostasis|G-protein coupled peptide receptor activity|G-protein coupled receptor activity|regulation of secretion|vasculature development|kinase activity|circulatory system development|cell surface receptor signaling pathway|negative regulation of smooth muscle cell proliferation|regulation of vasculature development|purine nucleotide metabolic process|nucleotide metabolic process|protein kinase activity|GTP binding|cellular protein modification process|ribonucleotide metabolic process|nucleotide biosynthetic process|catechol-containing compound metabolic process|ribose phosphate biosynthetic process|phosphorylation|ion homeostasis|regulation of blood vessel size|guanyl nucleotide binding|protein kinase binding|positive regulation of urine volume|ATP binding|regulation of vasodilation|enzyme linked receptor protein signaling pathway|receptor guanylyl cyclase signaling pathway|cyclic nucleotide metabolic process|vasodilation|purine nucleotide biosynthetic process|cyclic nucleotide biosynthetic process|positive regulation of cyclic nucleotide metabolic process|protein tyrosine kinase activity|protein phosphorylation|cGMP metabolic process|positive regulation of cGMP metabolic process|regulation of cGMP metabolic process|purine ribonucleotide biosynthetic process|metal ion homeostasis|regulation of cGMP biosynthetic process|positive regulation of cGMP biosynthetic process|cGMP biosynthetic process|sodium ion homeostasis" K12323 atrial natriuretic peptide receptor A[4.6.1.2] hsa04024|hsa00230|hsa04022|hsa04921|hsa04270|hsa04925|hsa04924|hsa04923 cAMP signaling pathway - Homo sapiens (human)|Purine metabolism - Homo sapiens (human)|cGMP-PKG signaling pathway - Homo sapiens (human)|Oxytocin signaling pathway - Homo sapiens (human)|Vascular smooth muscle contraction - Homo sapiens (human)|Aldosterone synthesis and secretion - Homo sapiens (human)|Renin secretion - Homo sapiens (human)|Regulation of lipolysis in adipocytes - Homo sapiens (human) chr1:153651113-153666468 2.557331885 1.261372756 1.019644724 0.000161126 0.005451046 UP ENSG00000132744 ACY3 aminoacylase 3 [Source:HGNC Symbol;Acc:HGNC:24104] - - - - - - chr11:67410026-67418130 1.61403212 0.773986777 1.060288466 0.000169094 0.005661236 UP ENSG00000110786 PTPN5 "protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched) [Source:HGNC Symbol;Acc:HGNC:9657]" GO:0016020|GO:0005623|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0012505|GO:0031224|GO:0031090|GO:0005622|GO:0043229|GO:0044237|GO:0005789|GO:0016787|GO:0005515|GO:0042175|GO:0043227|GO:0071704|GO:0016788|GO:0005737|GO:0051219|GO:0043231|GO:0016021|GO:0019538|GO:0098588|GO:0005783|GO:0042578|GO:0045309|GO:0044267|GO:0043412|GO:0006796|GO:0006464|GO:0016311|GO:0001784|GO:0016791|GO:0006470|GO:0004721|GO:0004725|GO:0035335 "membrane|cell|catalytic activity|organelle|cellular process|metabolic process|binding|endomembrane system|intrinsic component of membrane|organelle membrane|intracellular|intracellular organelle|cellular metabolic process|endoplasmic reticulum membrane|hydrolase activity|protein binding|nuclear outer membrane-endoplasmic reticulum membrane network|membrane-bounded organelle|organic substance metabolic process|hydrolase activity, acting on ester bonds|cytoplasm|phosphoprotein binding|intracellular membrane-bounded organelle|integral component of membrane|protein metabolic process|bounding membrane of organelle|endoplasmic reticulum|phosphoric ester hydrolase activity|protein phosphorylated amino acid binding|cellular protein metabolic process|macromolecule modification|phosphate-containing compound metabolic process|cellular protein modification process|dephosphorylation|phosphotyrosine binding|phosphatase activity|protein dephosphorylation|phosphoprotein phosphatase activity|protein tyrosine phosphatase activity|peptidyl-tyrosine dephosphorylation" K18018 tyrosine-protein phosphatase non-receptor type 5[3.1.3.48] hsa04010 MAPK signaling pathway - Homo sapiens (human) chr11:18749475-18814268 1.219843255 0.420648776 1.536007726 0.000171495 0.005707785 UP ENSG00000135519 KCNH3 "potassium channel, voltage gated eag related subfamily H, member 3 [Source:HGNC Symbol;Acc:HGNC:6252]" GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0003824|GO:0005215|GO:0009987|GO:0008152|GO:0005488|GO:0038023|GO:0031224|GO:0005057|GO:0044237|GO:0022857|GO:0050794|GO:0009058|GO:0051716|GO:0006807|GO:0071944|GO:0005886|GO:0005515|GO:0019222|GO:0016740|GO:0004872|GO:0071704|GO:0055085|GO:0071804|GO:0007267|GO:0022891|GO:1901360|GO:0044249|GO:0031226|GO:0006139|GO:0034641|GO:0006810|GO:0000155|GO:0006725|GO:0016021|GO:0005887|GO:0016772|GO:0019538|GO:0046483|GO:0031323|GO:0007165|GO:0023014|GO:0042391|GO:0007154|GO:0043269|GO:0010468|GO:0015075|GO:0006811|GO:0044267|GO:0009059|GO:0071805|GO:0043412|GO:0051252|GO:0034765|GO:0034220|GO:0035556|GO:0034645|GO:0016773|GO:0010467|GO:0006796|GO:0016301|GO:0016070|GO:0015267|GO:0005216|GO:0032774|GO:0004672|GO:0006464|GO:0006351|GO:0000160|GO:0016310|GO:0006355|GO:0008324|GO:0004673|GO:0006812|GO:0098655|GO:2001141|GO:0005261|GO:1903506|GO:0015672|GO:0007268|GO:0005244|GO:0006468|GO:0030001|GO:0022890|GO:0022843|GO:0005267|GO:0046873|GO:0006813|GO:0005249|GO:0015079 "signaling|membrane|cell|response to stimulus|signal transducer activity|catalytic activity|transporter activity|cellular process|metabolic process|binding|signaling receptor activity|intrinsic component of membrane|receptor signaling protein activity|cellular metabolic process|transmembrane transporter activity|regulation of cellular process|biosynthetic process|cellular response to stimulus|nitrogen compound metabolic process|cell periphery|plasma membrane|protein binding|regulation of metabolic process|transferase activity|receptor activity|organic substance metabolic process|transmembrane transport|cellular potassium ion transport|cell-cell signaling|substrate-specific transmembrane transporter activity|organic cyclic compound metabolic process|cellular biosynthetic process|intrinsic component of plasma membrane|nucleobase-containing compound metabolic process|cellular nitrogen compound metabolic process|transport|phosphorelay sensor kinase activity|cellular aromatic compound metabolic process|integral component of membrane|integral component of plasma membrane|transferase activity, transferring phosphorus-containing groups|protein metabolic process|heterocycle metabolic process|regulation of cellular metabolic process|signal transduction|signal transduction by protein phosphorylation|regulation of membrane potential|cell communication|regulation of ion transport|regulation of gene expression|ion transmembrane transporter activity|ion transport|cellular protein metabolic process|macromolecule biosynthetic process|potassium ion transmembrane transport|macromolecule modification|regulation of RNA metabolic process|regulation of ion transmembrane transport|ion transmembrane transport|intracellular signal transduction|cellular macromolecule biosynthetic process|phosphotransferase activity, alcohol group as acceptor|gene expression|phosphate-containing compound metabolic process|kinase activity|RNA metabolic process|channel activity|ion channel activity|RNA biosynthetic process|protein kinase activity|cellular protein modification process|transcription, DNA-templated|phosphorelay signal transduction system|phosphorylation|regulation of transcription, DNA-templated|cation transmembrane transporter activity|protein histidine kinase activity|cation transport|cation transmembrane transport|regulation of RNA biosynthetic process|cation channel activity|regulation of nucleic acid-templated transcription|monovalent inorganic cation transport|synaptic transmission|voltage-gated ion channel activity|protein phosphorylation|metal ion transport|inorganic cation transmembrane transporter activity|voltage-gated cation channel activity|potassium channel activity|metal ion transmembrane transporter activity|potassium ion transport|voltage-gated potassium channel activity|potassium ion transmembrane transporter activity" - - - - chr12:49932940-49952091 0.464843798 0.226810481 1.0352587 0.000184056 0.005945407 UP ENSG00000173762 CD7 CD7 molecule [Source:HGNC Symbol;Acc:HGNC:1695] GO:0023052|GO:0005576|GO:0016020|GO:0005623|GO:0050896|GO:0002376|GO:0043226|GO:0009987|GO:0005488|GO:0031224|GO:0006955|GO:0050794|GO:0051716|GO:0007155|GO:0071944|GO:0005886|GO:0005515|GO:0045321|GO:0043227|GO:0004872|GO:0042592|GO:0016337|GO:0046649|GO:0070062|GO:0001775|GO:0070489|GO:0016021|GO:0031982|GO:0048871|GO:0007165|GO:0098609|GO:0007154|GO:0048872|GO:0001894|GO:0042110|GO:0007159|GO:0007166|GO:0048873|GO:0070486|GO:0007167|GO:0007169|GO:0071593 signaling|extracellular region|membrane|cell|response to stimulus|immune system process|organelle|cellular process|binding|intrinsic component of membrane|immune response|regulation of cellular process|cellular response to stimulus|cell adhesion|cell periphery|plasma membrane|protein binding|leukocyte activation|membrane-bounded organelle|receptor activity|homeostatic process|single organismal cell-cell adhesion|lymphocyte activation|extracellular exosome|cell activation|T cell aggregation|integral component of membrane|vesicle|multicellular organismal homeostasis|signal transduction|cell-cell adhesion|cell communication|homeostasis of number of cells|tissue homeostasis|T cell activation|leukocyte cell-cell adhesion|cell surface receptor signaling pathway|homeostasis of number of cells within a tissue|leukocyte aggregation|enzyme linked receptor protein signaling pathway|transmembrane receptor protein tyrosine kinase signaling pathway|lymphocyte aggregation K06457 CD7 antigen[-] hsa04640 Hematopoietic cell lineage - Homo sapiens (human) chr17:80272744-80275478 1.278194162 0.621838476 1.039495212 0.00018436 0.005945407 UP ENSG00000018625 ATP1A2 "ATPase, Na+/K+ transporting, alpha 2 polypeptide [Source:HGNC Symbol;Acc:HGNC:800]" GO:0023052|GO:0040011|GO:0016020|GO:0005623|GO:0030054|GO:0050896|GO:0003824|GO:0005215|GO:0007610|GO:0043226|GO:0009987|GO:0045202|GO:0008152|GO:0032991|GO:0005488|GO:0012505|GO:0042562|GO:0031224|GO:0005622|GO:0043229|GO:0022857|GO:0050794|GO:0051716|GO:0009605|GO:0043167|GO:0051641|GO:0042995|GO:0097159|GO:0007626|GO:0071944|GO:0016787|GO:0097367|GO:0043209|GO:0051051|GO:0005886|GO:0005515|GO:0044708|GO:0048523|GO:0043234|GO:0008289|GO:0043227|GO:0036094|GO:0009628|GO:0005911|GO:0010033|GO:0010243|GO:0032410|GO:0042592|GO:0043197|GO:0044291|GO:0016817|GO:0007632|GO:0044092|GO:0055085|GO:0071804|GO:0044853|GO:0008344|GO:0003012|GO:0030029|GO:0022891|GO:0043005|GO:0005737|GO:0019725|GO:0002026|GO:0043271|GO:0051282|GO:0034763|GO:2000021|GO:0031226|GO:0003013|GO:0008217|GO:0060341|GO:0005496|GO:0032970|GO:0043231|GO:1990239|GO:0001505|GO:0009725|GO:0009314|GO:0006928|GO:0006810|GO:0043576|GO:0045932|GO:0016021|GO:0051238|GO:0005887|GO:0005768|GO:0007585|GO:0030534|GO:1902495|GO:0000166|GO:0051649|GO:0007611|GO:0009612|GO:0051270|GO:0043169|GO:0036477|GO:0042383|GO:0031982|GO:0050877|GO:0090533|GO:0007165|GO:0042391|GO:0007154|GO:0051087|GO:0030315|GO:0003016|GO:0001882|GO:0050890|GO:0051279|GO:0043269|GO:0010766|GO:0032386|GO:0033993|GO:0016820|GO:0035150|GO:1903416|GO:0048545|GO:0015075|GO:0006811|GO:0032549|GO:0009416|GO:0035639|GO:0017076|GO:0010522|GO:0006836|GO:0030048|GO:0014704|GO:0007612|GO:0071805|GO:0044309|GO:0006936|GO:0051208|GO:0001504|GO:0014070|GO:0051926|GO:0045822|GO:0030425|GO:0034765|GO:0051209|GO:0034766|GO:0046872|GO:0046907|GO:0045988|GO:0032870|GO:0001508|GO:0071260|GO:0034220|GO:0035556|GO:0002087|GO:0001883|GO:0045121|GO:0008015|GO:0048878|GO:0008542|GO:0005901|GO:0010644|GO:0044065|GO:0016818|GO:0043279|GO:0061337|GO:0005890|GO:0051899|GO:0055082|GO:0071310|GO:0022898|GO:0008306|GO:0006873|GO:0071407|GO:0006941|GO:0070296|GO:0086001|GO:0015992|GO:0090279|GO:0086064|GO:0086004|GO:2000650|GO:0010880|GO:0042626|GO:0050801|GO:0055119|GO:0006937|GO:0086010|GO:0050880|GO:1901020|GO:0035094|GO:0008324|GO:0019229|GO:0019932|GO:0071396|GO:1903170|GO:0016482|GO:0070252|GO:0032412|GO:0014808|GO:0005524|GO:0010107|GO:0060047|GO:0071383|GO:0006812|GO:0098655|GO:0060402|GO:0006939|GO:1902306|GO:0015991|GO:0008016|GO:0016462|GO:0019829|GO:1902600|GO:0086012|GO:1902305|GO:0051924|GO:0015672|GO:0002028|GO:0042310|GO:0055117|GO:0086003|GO:0030003|GO:0017111|GO:0006942|GO:0060048|GO:0010881|GO:1901019|GO:1903280|GO:0030001|GO:1903169|GO:0006940|GO:0022890|GO:2000649|GO:0019722|GO:0006814|GO:0070588|GO:0055065|GO:0046873|GO:0006813|GO:0016887|GO:0010882|GO:0006875|GO:0035725|GO:0042623|GO:0071436|GO:0030007|GO:0006816|GO:0055074|GO:0055078|GO:0055075|GO:0005391|GO:0006874|GO:0015081|GO:0006883|GO:0015079|GO:0070509|GO:0036376|GO:0060401|GO:0051480|GO:0051481|GO:0007204 "signaling|locomotion|membrane|cell|cell junction|response to stimulus|catalytic activity|transporter activity|behavior|organelle|cellular process|synapse|metabolic process|macromolecular complex|binding|endomembrane system|hormone binding|intrinsic component of membrane|intracellular|intracellular organelle|transmembrane transporter activity|regulation of cellular process|cellular response to stimulus|response to external stimulus|ion binding|cellular localization|cell projection|organic cyclic compound binding|locomotory behavior|cell periphery|hydrolase activity|carbohydrate derivative binding|myelin sheath|negative regulation of transport|plasma membrane|protein binding|single-organism behavior|negative regulation of cellular process|protein complex|lipid binding|membrane-bounded organelle|small molecule binding|response to abiotic stimulus|cell-cell junction|response to organic substance|response to organonitrogen compound|negative regulation of transporter activity|homeostatic process|dendritic spine|cell-cell contact zone|hydrolase activity, acting on acid anhydrides|visual behavior|negative regulation of molecular function|transmembrane transport|cellular potassium ion transport|plasma membrane raft|adult locomotory behavior|muscle system process|actin filament-based process|substrate-specific transmembrane transporter activity|neuron projection|cytoplasm|cellular homeostasis|regulation of the force of heart contraction|negative regulation of ion transport|regulation of sequestering of calcium ion|negative regulation of transmembrane transport|regulation of ion homeostasis|intrinsic component of plasma membrane|circulatory system process|regulation of blood pressure|regulation of cellular localization|steroid binding|regulation of actin filament-based process|intracellular membrane-bounded organelle|steroid hormone binding|regulation of neurotransmitter levels|response to hormone|response to radiation|movement of cell or subcellular component|transport|regulation of respiratory gaseous exchange|negative regulation of muscle contraction|integral component of membrane|sequestering of metal ion|integral component of plasma membrane|endosome|respiratory gaseous exchange|adult behavior|transmembrane transporter complex|nucleotide binding|establishment of localization in cell|learning or memory|response to mechanical stimulus|regulation of cellular component movement|cation binding|somatodendritic compartment|sarcolemma|vesicle|neurological system process|cation-transporting ATPase complex|signal transduction|regulation of membrane potential|cell communication|chaperone binding|T-tubule|respiratory system process|nucleoside binding|cognition|regulation of release of sequestered calcium ion into cytosol|regulation of ion transport|negative regulation of sodium ion transport|regulation of intracellular transport|response to lipid|hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances|regulation of tube size|response to glycoside|response to steroid hormone|ion transmembrane transporter activity|ion transport|ribonucleoside binding|response to light stimulus|purine ribonucleoside triphosphate binding|purine nucleotide binding|regulation of calcium ion transport into cytosol|neurotransmitter transport|actin filament-based movement|intercalated disc|learning|potassium ion transmembrane transport|neuron spine|muscle contraction|sequestering of calcium ion|neurotransmitter uptake|response to organic cyclic compound|negative regulation of calcium ion transport|negative regulation of heart contraction|dendrite|regulation of ion transmembrane transport|release of sequestered calcium ion into cytosol|negative regulation of ion transmembrane transport|metal ion binding|intracellular transport|negative regulation of striated muscle contraction|cellular response to hormone stimulus|action potential|cellular response to mechanical stimulus|ion transmembrane transport|intracellular signal transduction|regulation of respiratory gaseous exchange by neurological system process|purine nucleoside binding|membrane raft|blood circulation|chemical homeostasis|visual learning|caveola|cell communication by electrical coupling|regulation of respiratory system process|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|response to alkaloid|cardiac conduction|sodium:potassium-exchanging ATPase complex|membrane depolarization|cellular chemical homeostasis|cellular response to organic substance|regulation of transmembrane transporter activity|associative learning|cellular ion homeostasis|cellular response to organic cyclic compound|striated muscle contraction|sarcoplasmic reticulum calcium ion transport|cardiac muscle cell action potential|proton transport|regulation of calcium ion import|cell communication by electrical coupling involved in cardiac conduction|regulation of cardiac muscle cell contraction|negative regulation of sodium ion transmembrane transporter activity|regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|ATPase activity, coupled to transmembrane movement of substances|ion homeostasis|relaxation of cardiac muscle|regulation of muscle contraction|membrane depolarization during action potential|regulation of blood vessel size|negative regulation of calcium ion transmembrane transporter activity|response to nicotine|cation transmembrane transporter activity|regulation of vasoconstriction|second-messenger-mediated signaling|cellular response to lipid|negative regulation of calcium ion transmembrane transport|cytosolic transport|actin-mediated cell contraction|regulation of ion transmembrane transporter activity|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|ATP binding|potassium ion import|heart contraction|cellular response to steroid hormone stimulus|cation transport|cation transmembrane transport|calcium ion transport into cytosol|smooth muscle contraction|negative regulation of sodium ion transmembrane transport|ATP hydrolysis coupled proton transport|regulation of heart contraction|pyrophosphatase activity|cation-transporting ATPase activity|hydrogen ion transmembrane transport|membrane depolarization during cardiac muscle cell action potential|regulation of sodium ion transmembrane transport|regulation of calcium ion transport|monovalent inorganic cation transport|regulation of sodium ion transport|vasoconstriction|regulation of cardiac muscle contraction|cardiac muscle cell contraction|cellular cation homeostasis|nucleoside-triphosphatase activity|regulation of striated muscle contraction|cardiac muscle contraction|regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion|regulation of calcium ion transmembrane transporter activity|negative regulation of calcium:sodium antiporter activity|metal ion transport|regulation of calcium ion transmembrane transport|regulation of smooth muscle contraction|inorganic cation transmembrane transporter activity|regulation of sodium ion transmembrane transporter activity|calcium-mediated signaling|sodium ion transport|calcium ion transmembrane transport|metal ion homeostasis|metal ion transmembrane transporter activity|potassium ion transport|ATPase activity|regulation of cardiac muscle contraction by calcium ion signaling|cellular metal ion homeostasis|sodium ion transmembrane transport|ATPase activity, coupled|sodium ion export|cellular potassium ion homeostasis|calcium ion transport|calcium ion homeostasis|sodium ion homeostasis|potassium ion homeostasis|sodium:potassium-exchanging ATPase activity|cellular calcium ion homeostasis|sodium ion transmembrane transporter activity|cellular sodium ion homeostasis|potassium ion transmembrane transporter activity|calcium ion import|sodium ion export from cell|cytosolic calcium ion transport|regulation of cytosolic calcium ion concentration|negative regulation of cytosolic calcium ion concentration|positive regulation of cytosolic calcium ion concentration" K01539 sodium/potassium-transporting ATPase subunit alpha[3.6.3.9] hsa04024|hsa04022|hsa04261|hsa04919|hsa04972|hsa04974|hsa04970|hsa04911|hsa04260|hsa04971|hsa04976|hsa04918|hsa04978|hsa04961|hsa04973|hsa04960|hsa04964 cAMP signaling pathway - Homo sapiens (human)|cGMP-PKG signaling pathway - Homo sapiens (human)|Adrenergic signaling in cardiomyocytes - Homo sapiens (human)|Thyroid hormone signaling pathway - Homo sapiens (human)|Pancreatic secretion - Homo sapiens (human)|Protein digestion and absorption - Homo sapiens (human)|Salivary secretion - Homo sapiens (human)|Insulin secretion - Homo sapiens (human)|Cardiac muscle contraction - Homo sapiens (human)|Gastric acid secretion - Homo sapiens (human)|Bile secretion - Homo sapiens (human)|Thyroid hormone synthesis - Homo sapiens (human)|Mineral absorption - Homo sapiens (human)|Endocrine and other factor-regulated calcium reabsorption - Homo sapiens (human)|Carbohydrate digestion and absorption - Homo sapiens (human)|Aldosterone-regulated sodium reabsorption - Homo sapiens (human)|Proximal tubule bicarbonate reclamation - Homo sapiens (human) chr1:160085563-160113381 8.196413641 3.715263628 1.141528208 0.000189735 0.006038989 UP ENSG00000143382 ADAMTSL4 ADAMTS like 4 [Source:HGNC Symbol;Acc:HGNC:19706] GO:0005576|GO:0031012|GO:0005623|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0012505|GO:0005622|GO:0043229|GO:0044237|GO:0016043|GO:0050794|GO:0009058|GO:0016787|GO:0005515|GO:0043227|GO:0005578|GO:0071704|GO:0008233|GO:0043062|GO:0005737|GO:0005614|GO:0044249|GO:0043231|GO:0019899|GO:0010942|GO:0008219|GO:0019538|GO:0005783|GO:0005975|GO:0010941|GO:0006486|GO:0043068|GO:0006493|GO:0070085|GO:0044267|GO:0005788|GO:0009059|GO:0009100|GO:0043067|GO:0043412|GO:0030198|GO:0002020|GO:0006508|GO:1901137|GO:0034645|GO:0012501|GO:0006464|GO:0043413|GO:0036065|GO:0009101|GO:0008237|GO:0043065|GO:0004175|GO:0006915|GO:0042981|GO:0036066|GO:0004222|GO:0043687 extracellular region|extracellular matrix|cell|catalytic activity|organelle|cellular process|metabolic process|binding|endomembrane system|intracellular|intracellular organelle|cellular metabolic process|cellular component organization|regulation of cellular process|biosynthetic process|hydrolase activity|protein binding|membrane-bounded organelle|proteinaceous extracellular matrix|organic substance metabolic process|peptidase activity|extracellular structure organization|cytoplasm|interstitial matrix|cellular biosynthetic process|intracellular membrane-bounded organelle|enzyme binding|positive regulation of cell death|cell death|protein metabolic process|endoplasmic reticulum|carbohydrate metabolic process|regulation of cell death|protein glycosylation|positive regulation of programmed cell death|protein O-linked glycosylation|glycosylation|cellular protein metabolic process|endoplasmic reticulum lumen|macromolecule biosynthetic process|glycoprotein metabolic process|regulation of programmed cell death|macromolecule modification|extracellular matrix organization|protease binding|proteolysis|carbohydrate derivative biosynthetic process|cellular macromolecule biosynthetic process|programmed cell death|cellular protein modification process|macromolecule glycosylation|fucosylation|glycoprotein biosynthetic process|metallopeptidase activity|positive regulation of apoptotic process|endopeptidase activity|apoptotic process|regulation of apoptotic process|protein O-linked fucosylation|metalloendopeptidase activity|post-translational protein modification - - - - chr1:150521884-150533413 10.70919463 5.087299445 1.073878068 0.000204727 0.00637523 UP ENSG00000145681 HAPLN1 hyaluronan and proteoglycan link protein 1 [Source:HGNC Symbol;Acc:HGNC:2380] GO:0005576|GO:0016020|GO:0031012|GO:0005198|GO:0050896|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0009056|GO:0048856|GO:0044237|GO:0016043|GO:0050794|GO:0051716|GO:0009605|GO:0006950|GO:0007155|GO:0097367|GO:0005515|GO:0005201|GO:0019222|GO:0005578|GO:0006914|GO:0005539|GO:0051128|GO:0016236|GO:0033554|GO:0043062|GO:0048731|GO:0007275|GO:0009991|GO:0031323|GO:0006996|GO:0000422|GO:0010646|GO:0007154|GO:0010506|GO:0007417|GO:0005540|GO:0007399|GO:0001501|GO:1903146|GO:1903008|GO:0030198|GO:0016241|GO:0031667|GO:0007005|GO:0033043|GO:0010821 extracellular region|membrane|extracellular matrix|structural molecule activity|response to stimulus|cellular process|metabolic process|developmental process|binding|catabolic process|anatomical structure development|cellular metabolic process|cellular component organization|regulation of cellular process|cellular response to stimulus|response to external stimulus|response to stress|cell adhesion|carbohydrate derivative binding|protein binding|extracellular matrix structural constituent|regulation of metabolic process|proteinaceous extracellular matrix|autophagy|glycosaminoglycan binding|regulation of cellular component organization|macroautophagy|cellular response to stress|extracellular structure organization|system development|multicellular organism development|response to extracellular stimulus|regulation of cellular metabolic process|organelle organization|mitophagy|regulation of cell communication|cell communication|regulation of autophagy|central nervous system development|hyaluronic acid binding|nervous system development|skeletal system development|regulation of mitophagy|organelle disassembly|extracellular matrix organization|regulation of macroautophagy|response to nutrient levels|mitochondrion organization|regulation of organelle organization|regulation of mitochondrion organization - - - - chr5:82933624-83017432 0.38849558 0.11479106 1.758887896 0.00022783 0.006924304 UP ENSG00000251576 RP11-536I6.1 long intergenic non-protein coding RNA 1267 [Source:HGNC Symbol;Acc:HGNC:50320] - - - - - - chr3:14389951-14394068 1.923111467 0.959809122 1.002622957 0.000228011 0.006924304 UP ENSG00000198003 CCDC151 coiled-coil domain containing 151 [Source:HGNC Symbol;Acc:HGNC:28303] GO:0005623|GO:0043226|GO:0009987|GO:0032502|GO:0005488|GO:0005622|GO:0043229|GO:0048856|GO:0016043|GO:0050794|GO:0005929|GO:0042995|GO:0048646|GO:0005515|GO:0009653|GO:0050793|GO:0060491|GO:0051128|GO:0030030|GO:0005737|GO:0048869|GO:0022607|GO:0007017|GO:0005930|GO:0006928|GO:0036064|GO:0006996|GO:0031344|GO:0005815|GO:0042384|GO:1902017|GO:0000902|GO:0032990|GO:0022604|GO:0005814|GO:0048858|GO:0030031|GO:0044782|GO:0070925|GO:0005813|GO:0005856|GO:0033043|GO:0007018|GO:0003341|GO:0015630|GO:0060271 cell|organelle|cellular process|developmental process|binding|intracellular|intracellular organelle|anatomical structure development|cellular component organization|regulation of cellular process|cilium|cell projection|anatomical structure formation involved in morphogenesis|protein binding|anatomical structure morphogenesis|regulation of developmental process|regulation of cell projection assembly|regulation of cellular component organization|cell projection organization|cytoplasm|cellular developmental process|cellular component assembly|microtubule-based process|axoneme|movement of cell or subcellular component|ciliary basal body|organelle organization|regulation of cell projection organization|microtubule organizing center|cilium assembly|regulation of cilium assembly|cell morphogenesis|cell part morphogenesis|regulation of cell morphogenesis|centriole|cell projection morphogenesis|cell projection assembly|cilium organization|organelle assembly|centrosome|cytoskeleton|regulation of organelle organization|microtubule-based movement|cilium movement|microtubule cytoskeleton|cilium morphogenesis - - - - chr19:11531272-11546603 0.238434842 0.099974407 1.25396434 0.000249982 0.00735778 UP ENSG00000167549 CORO6 coronin 6 [Source:HGNC Symbol;Acc:HGNC:21356] GO:0005623|GO:0043226|GO:0009987|GO:0005488|GO:0005622|GO:0043229|GO:0016043|GO:0005515|GO:0008092|GO:0030029|GO:0032403|GO:0006996|GO:0007010|GO:0030036|GO:0003779|GO:0005856|GO:0051015|GO:0015629 cell|organelle|cellular process|binding|intracellular|intracellular organelle|cellular component organization|protein binding|cytoskeletal protein binding|actin filament-based process|protein complex binding|organelle organization|cytoskeleton organization|actin cytoskeleton organization|actin binding|cytoskeleton|actin filament binding|actin cytoskeleton - - - - chr17:27941774-27949922 1.412870537 0.691581475 1.030658146 0.000274922 0.007911442 UP ENSG00000185186 LINC00313 long intergenic non-protein coding RNA 313 [Source:HGNC Symbol;Acc:HGNC:16416] - - - - - - chr21:44881974-44899414 0.487209568 0.202001362 1.270177444 0.000298348 0.008370235 UP ENSG00000075035 WSCD2 WSC domain containing 2 [Source:HGNC Symbol;Acc:HGNC:29117] - - - - - - chr12:108523248-108644314 0.614872602 0.177106145 1.795673255 0.000328008 0.008997732 UP ENSG00000180287 PLD5 phospholipase D family member 5 [Source:HGNC Symbol;Acc:HGNC:26879] GO:0016020|GO:0003824|GO:0008152|GO:0031224|GO:0016021 membrane|catalytic activity|metabolic process|intrinsic component of membrane|integral component of membrane - - - - chr1:242252271-242687998 0.072851126 0.013805733 2.399683744 0.000330527 0.009028453 UP ENSG00000087494 PTHLH parathyroid hormone-like hormone [Source:HGNC Symbol;Acc:HGNC:9607] GO:0023052|GO:0005576|GO:0022414|GO:0005623|GO:0050896|GO:0000003|GO:0040007|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0012505|GO:0009893|GO:0008283|GO:0005622|GO:0048589|GO:0043229|GO:0048856|GO:0044237|GO:0050794|GO:0009058|GO:0051716|GO:0006807|GO:0048646|GO:0005515|GO:0009653|GO:0019222|GO:0050793|GO:0009892|GO:0048523|GO:0005615|GO:0043227|GO:0071704|GO:0042592|GO:0044092|GO:0007565|GO:0005102|GO:0045596|GO:0048468|GO:0060560|GO:0007267|GO:0009888|GO:0008285|GO:0060348|GO:0035295|GO:0048731|GO:1901360|GO:0005737|GO:0030323|GO:0045595|GO:0044249|GO:0006139|GO:0001503|GO:0035239|GO:0048869|GO:0007275|GO:0043231|GO:0034641|GO:0005794|GO:0061037|GO:0048286|GO:0006725|GO:0009890|GO:0060659|GO:0055086|GO:0031325|GO:0019538|GO:0031324|GO:0019637|GO:0042127|GO:0009887|GO:0046483|GO:0008284|GO:0044281|GO:0048729|GO:0031323|GO:0048513|GO:0048871|GO:0051090|GO:0030324|GO:0007165|GO:0007154|GO:0048732|GO:0043433|GO:0031328|GO:0022612|GO:0019693|GO:0010468|GO:0005634|GO:0030154|GO:0030879|GO:0060562|GO:0051604|GO:0060649|GO:0001894|GO:0032331|GO:0060429|GO:0001649|GO:0010629|GO:0005654|GO:0032330|GO:0009059|GO:0061448|GO:0051174|GO:0007492|GO:0007186|GO:0001501|GO:0048705|GO:0051252|GO:0061035|GO:0031981|GO:0006508|GO:0002076|GO:1901137|GO:0051216|GO:0060541|GO:0034645|GO:0010467|GO:0006796|GO:0048878|GO:0060349|GO:0051427|GO:0005179|GO:0016070|GO:0002009|GO:0006163|GO:0009117|GO:0008544|GO:0032774|GO:0009259|GO:0009165|GO:0006351|GO:0048875|GO:0046390|GO:0045892|GO:0060443|GO:0060571|GO:0006355|GO:0051428|GO:0060350|GO:1902679|GO:0060603|GO:0061180|GO:0002062|GO:0001958|GO:0007187|GO:2001141|GO:0016485|GO:0030855|GO:1903506|GO:0009187|GO:0043129|GO:0060648|GO:1903507|GO:0006164|GO:0009190|GO:0030801|GO:0007188|GO:0030816|GO:0007189|GO:0030814|GO:0009152|GO:0046058|GO:0030817|GO:0030819|GO:0006171 "signaling|extracellular region|reproductive process|cell|response to stimulus|reproduction|growth|organelle|cellular process|metabolic process|developmental process|binding|endomembrane system|positive regulation of metabolic process|cell proliferation|intracellular|developmental growth|intracellular organelle|anatomical structure development|cellular metabolic process|regulation of cellular process|biosynthetic process|cellular response to stimulus|nitrogen compound metabolic process|anatomical structure formation involved in morphogenesis|protein binding|anatomical structure morphogenesis|regulation of metabolic process|regulation of developmental process|negative regulation of metabolic process|negative regulation of cellular process|extracellular space|membrane-bounded organelle|organic substance metabolic process|homeostatic process|negative regulation of molecular function|female pregnancy|receptor binding|negative regulation of cell differentiation|cell development|developmental growth involved in morphogenesis|cell-cell signaling|tissue development|negative regulation of cell proliferation|bone development|tube development|system development|organic cyclic compound metabolic process|cytoplasm|respiratory tube development|regulation of cell differentiation|cellular biosynthetic process|nucleobase-containing compound metabolic process|ossification|tube morphogenesis|cellular developmental process|multicellular organism development|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|Golgi apparatus|negative regulation of cartilage development|lung alveolus development|cellular aromatic compound metabolic process|negative regulation of biosynthetic process|nipple sheath formation|nucleobase-containing small molecule metabolic process|positive regulation of cellular metabolic process|protein metabolic process|negative regulation of cellular metabolic process|organophosphate metabolic process|regulation of cell proliferation|organ morphogenesis|heterocycle metabolic process|positive regulation of cell proliferation|small molecule metabolic process|tissue morphogenesis|regulation of cellular metabolic process|animal organ development|multicellular organismal homeostasis|regulation of sequence-specific DNA binding transcription factor activity|lung development|signal transduction|cell communication|gland development|negative regulation of sequence-specific DNA binding transcription factor activity|positive regulation of cellular biosynthetic process|gland morphogenesis|ribose phosphate metabolic process|regulation of gene expression|nucleus|cell differentiation|mammary gland development|epithelial tube morphogenesis|protein maturation|mammary gland bud elongation|tissue homeostasis|negative regulation of chondrocyte differentiation|epithelium development|osteoblast differentiation|negative regulation of gene expression|nucleoplasm|regulation of chondrocyte differentiation|macromolecule biosynthetic process|connective tissue development|regulation of phosphorus metabolic process|endoderm development|G-protein coupled receptor signaling pathway|skeletal system development|skeletal system morphogenesis|regulation of RNA metabolic process|regulation of cartilage development|nuclear lumen|proteolysis|osteoblast development|carbohydrate derivative biosynthetic process|cartilage development|respiratory system development|cellular macromolecule biosynthetic process|gene expression|phosphate-containing compound metabolic process|chemical homeostasis|bone morphogenesis|hormone receptor binding|hormone activity|RNA metabolic process|morphogenesis of an epithelium|purine nucleotide metabolic process|nucleotide metabolic process|epidermis development|RNA biosynthetic process|ribonucleotide metabolic process|nucleotide biosynthetic process|transcription, DNA-templated|chemical homeostasis within a tissue|ribose phosphate biosynthetic process|negative regulation of transcription, DNA-templated|mammary gland morphogenesis|morphogenesis of an epithelial fold|regulation of transcription, DNA-templated|peptide hormone receptor binding|endochondral bone morphogenesis|negative regulation of RNA biosynthetic process|mammary gland duct morphogenesis|mammary gland epithelium development|chondrocyte differentiation|endochondral ossification|G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|regulation of RNA biosynthetic process|protein processing|epithelial cell differentiation|regulation of nucleic acid-templated transcription|cyclic nucleotide metabolic process|surfactant homeostasis|mammary gland bud morphogenesis|negative regulation of nucleic acid-templated transcription|purine nucleotide biosynthetic process|cyclic nucleotide biosynthetic process|positive regulation of cyclic nucleotide metabolic process|adenylate cyclase-modulating G-protein coupled receptor signaling pathway|positive regulation of cAMP metabolic process|adenylate cyclase-activating G-protein coupled receptor signaling pathway|regulation of cAMP metabolic process|purine ribonucleotide biosynthetic process|cAMP metabolic process|regulation of cAMP biosynthetic process|positive regulation of cAMP biosynthetic process|cAMP biosynthetic process" - - - - chr12:28111017-28125638 1.190182137 0.376271473 1.661336549 0.000331647 0.009043186 UP ENSG00000102678 FGF9 fibroblast growth factor 9 [Source:HGNC Symbol;Acc:HGNC:3687] GO:0023052|GO:0005576|GO:0022414|GO:0031012|GO:0005623|GO:0050896|GO:0002376|GO:0000003|GO:0040007|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0009893|GO:0044702|GO:0023057|GO:0045927|GO:0008283|GO:0040008|GO:0006955|GO:0005622|GO:0048589|GO:0048856|GO:0044237|GO:0050794|GO:0009058|GO:0051716|GO:0043167|GO:0051641|GO:0006950|GO:0006807|GO:0048646|GO:0003006|GO:0097367|GO:0005604|GO:0005515|GO:0009653|GO:0019222|GO:0050793|GO:0009892|GO:0048523|GO:0005615|GO:0043227|GO:0002682|GO:0005578|GO:0071704|GO:0045087|GO:0010033|GO:0007548|GO:0010243|GO:0051302|GO:0005539|GO:0006952|GO:0048638|GO:0050776|GO:0048857|GO:0005102|GO:0007420|GO:0007267|GO:0009888|GO:0055017|GO:0001568|GO:0045184|GO:0035295|GO:0048731|GO:1901360|GO:0005737|GO:0051781|GO:0048568|GO:0007423|GO:0030323|GO:0045595|GO:0071774|GO:0051301|GO:0009968|GO:0007530|GO:0044249|GO:0046620|GO:0006139|GO:0001503|GO:0008104|GO:0048869|GO:1901863|GO:0007275|GO:0009966|GO:0048608|GO:0070062|GO:0034641|GO:0048639|GO:0009725|GO:0009967|GO:0006810|GO:0008406|GO:0006725|GO:0072089|GO:0009890|GO:0061061|GO:0040034|GO:0031325|GO:0051649|GO:0019538|GO:0007507|GO:0030901|GO:0031324|GO:0048514|GO:0042127|GO:0048598|GO:0050673|GO:0009887|GO:0046483|GO:0008284|GO:0048565|GO:0046622|GO:0031323|GO:0031982|GO:0048513|GO:0030324|GO:0007165|GO:0023014|GO:0010646|GO:0007154|GO:0060322|GO:0035265|GO:0048839|GO:0001525|GO:0008201|GO:0070851|GO:0010628|GO:0046661|GO:0030949|GO:0060421|GO:0060420|GO:0048566|GO:0016202|GO:0043583|GO:0010468|GO:0034613|GO:0009790|GO:0030238|GO:0007417|GO:0060043|GO:0030154|GO:0070848|GO:0030177|GO:0017038|GO:0060038|GO:0044344|GO:0060485|GO:0060173|GO:0044267|GO:0060484|GO:0001649|GO:0010629|GO:0071417|GO:0032270|GO:0009059|GO:0061448|GO:0072091|GO:0042472|GO:0007399|GO:0051174|GO:0072358|GO:0000165|GO:0001501|GO:0030947|GO:0061458|GO:0051247|GO:0043412|GO:0051252|GO:0007517|GO:0043434|GO:0015031|GO:0046907|GO:1901652|GO:0050678|GO:0030178|GO:0032870|GO:0001654|GO:0051216|GO:0051246|GO:0035556|GO:0060541|GO:0055123|GO:0072594|GO:0034645|GO:1902533|GO:0010467|GO:0006796|GO:0021762|GO:0008589|GO:0008584|GO:0035108|GO:0048505|GO:0048738|GO:0001944|GO:0010463|GO:0072359|GO:0007166|GO:0016070|GO:0060045|GO:0060419|GO:0008083|GO:2000648|GO:0030111|GO:0045844|GO:0048562|GO:0045880|GO:0002764|GO:0006606|GO:0032268|GO:0050679|GO:0071310|GO:0008543|GO:0060828|GO:0006886|GO:0048706|GO:0032774|GO:0006464|GO:0005104|GO:0042471|GO:0006351|GO:0016055|GO:0032868|GO:0002053|GO:0071363|GO:0002768|GO:0032927|GO:0045892|GO:0016310|GO:0038179|GO:0030326|GO:0051169|GO:0033365|GO:0006355|GO:0071375|GO:0055024|GO:0009792|GO:0031401|GO:1901653|GO:0043408|GO:0007224|GO:1902679|GO:0032925|GO:0014706|GO:0090263|GO:0006605|GO:0002062|GO:0048017|GO:2001141|GO:0010464|GO:0007167|GO:0043410|GO:0006357|GO:0034504|GO:1903506|GO:0006913|GO:0060070|GO:0001932|GO:0001934|GO:0032869|GO:1903507|GO:0007169|GO:0043009|GO:0042327|GO:0038093|GO:0042325|GO:0048011|GO:0006366|GO:0007178|GO:0048015|GO:0000122|GO:0006468|GO:0038095|GO:0008286|GO:0048010|GO:0051170|GO:0038127|GO:0032924|GO:0007173 "signaling|extracellular region|reproductive process|extracellular matrix|cell|response to stimulus|immune system process|reproduction|growth|organelle|cellular process|metabolic process|developmental process|binding|positive regulation of metabolic process|single organism reproductive process|negative regulation of signaling|positive regulation of growth|cell proliferation|regulation of growth|immune response|intracellular|developmental growth|anatomical structure development|cellular metabolic process|regulation of cellular process|biosynthetic process|cellular response to stimulus|ion binding|cellular localization|response to stress|nitrogen compound metabolic process|anatomical structure formation involved in morphogenesis|developmental process involved in reproduction|carbohydrate derivative binding|basement membrane|protein binding|anatomical structure morphogenesis|regulation of metabolic process|regulation of developmental process|negative regulation of metabolic process|negative regulation of cellular process|extracellular space|membrane-bounded organelle|regulation of immune system process|proteinaceous extracellular matrix|organic substance metabolic process|innate immune response|response to organic substance|sex differentiation|response to organonitrogen compound|regulation of cell division|glycosaminoglycan binding|defense response|regulation of developmental growth|regulation of immune response|neural nucleus development|receptor binding|brain development|cell-cell signaling|tissue development|cardiac muscle tissue growth|blood vessel development|establishment of protein localization|tube development|system development|organic cyclic compound metabolic process|cytoplasm|positive regulation of cell division|embryonic organ development|sensory organ development|respiratory tube development|regulation of cell differentiation|response to fibroblast growth factor|cell division|negative regulation of signal transduction|sex determination|cellular biosynthetic process|regulation of organ growth|nucleobase-containing compound metabolic process|ossification|protein localization|cellular developmental process|positive regulation of muscle tissue development|multicellular organism development|regulation of signal transduction|reproductive structure development|extracellular exosome|cellular nitrogen compound metabolic process|positive regulation of developmental growth|response to hormone|positive regulation of signal transduction|transport|gonad development|cellular aromatic compound metabolic process|stem cell proliferation|negative regulation of biosynthetic process|muscle structure development|regulation of development, heterochronic|positive regulation of cellular metabolic process|establishment of localization in cell|protein metabolic process|heart development|midbrain development|negative regulation of cellular metabolic process|blood vessel morphogenesis|regulation of cell proliferation|embryonic morphogenesis|epithelial cell proliferation|organ morphogenesis|heterocycle metabolic process|positive regulation of cell proliferation|digestive tract development|positive regulation of organ growth|regulation of cellular metabolic process|vesicle|animal organ development|lung development|signal transduction|signal transduction by protein phosphorylation|regulation of cell communication|cell communication|head development|organ growth|inner ear development|angiogenesis|heparin binding|growth factor receptor binding|positive regulation of gene expression|male sex differentiation|positive regulation of vascular endothelial growth factor receptor signaling pathway|positive regulation of heart growth|regulation of heart growth|embryonic digestive tract development|regulation of striated muscle tissue development|ear development|regulation of gene expression|cellular protein localization|embryo development|male sex determination|central nervous system development|regulation of cardiac muscle cell proliferation|cell differentiation|response to growth factor|positive regulation of Wnt signaling pathway|protein import|cardiac muscle cell proliferation|cellular response to fibroblast growth factor stimulus|mesenchyme development|limb development|cellular protein metabolic process|lung-associated mesenchyme development|osteoblast differentiation|negative regulation of gene expression|cellular response to organonitrogen compound|positive regulation of cellular protein metabolic process|macromolecule biosynthetic process|connective tissue development|regulation of stem cell proliferation|inner ear morphogenesis|nervous system development|regulation of phosphorus metabolic process|cardiovascular system development|MAPK cascade|skeletal system development|regulation of vascular endothelial growth factor receptor signaling pathway|reproductive system development|positive regulation of protein metabolic process|macromolecule modification|regulation of RNA metabolic process|muscle organ development|response to peptide hormone|protein transport|intracellular transport|response to peptide|regulation of epithelial cell proliferation|negative regulation of Wnt signaling pathway|cellular response to hormone stimulus|eye development|cartilage development|regulation of protein metabolic process|intracellular signal transduction|respiratory system development|digestive system development|establishment of protein localization to organelle|cellular macromolecule biosynthetic process|positive regulation of intracellular signal transduction|gene expression|phosphate-containing compound metabolic process|substantia nigra development|regulation of smoothened signaling pathway|male gonad development|limb morphogenesis|regulation of timing of cell differentiation|cardiac muscle tissue development|vasculature development|mesenchymal cell proliferation|circulatory system development|cell surface receptor signaling pathway|RNA metabolic process|positive regulation of cardiac muscle cell proliferation|heart growth|growth factor activity|positive regulation of stem cell proliferation|regulation of Wnt signaling pathway|positive regulation of striated muscle tissue development|embryonic organ morphogenesis|positive regulation of smoothened signaling pathway|immune response-regulating signaling pathway|protein import into nucleus|regulation of cellular protein metabolic process|positive regulation of epithelial cell proliferation|cellular response to organic substance|fibroblast growth factor receptor signaling pathway|regulation of canonical Wnt signaling pathway|intracellular protein transport|embryonic skeletal system development|RNA biosynthetic process|cellular protein modification process|fibroblast growth factor receptor binding|ear morphogenesis|transcription, DNA-templated|Wnt signaling pathway|response to insulin|positive regulation of mesenchymal cell proliferation|cellular response to growth factor stimulus|immune response-regulating cell surface receptor signaling pathway|positive regulation of activin receptor signaling pathway|negative regulation of transcription, DNA-templated|phosphorylation|neurotrophin signaling pathway|embryonic limb morphogenesis|nuclear transport|protein localization to organelle|regulation of transcription, DNA-templated|cellular response to peptide hormone stimulus|regulation of cardiac muscle tissue development|embryo development ending in birth or egg hatching|positive regulation of protein modification process|cellular response to peptide|regulation of MAPK cascade|smoothened signaling pathway|negative regulation of RNA biosynthetic process|regulation of activin receptor signaling pathway|striated muscle tissue development|positive regulation of canonical Wnt signaling pathway|protein targeting|chondrocyte differentiation|inositol lipid-mediated signaling|regulation of RNA biosynthetic process|regulation of mesenchymal cell proliferation|enzyme linked receptor protein signaling pathway|positive regulation of MAPK cascade|regulation of transcription from RNA polymerase II promoter|protein localization to nucleus|regulation of nucleic acid-templated transcription|nucleocytoplasmic transport|canonical Wnt signaling pathway|regulation of protein phosphorylation|positive regulation of protein phosphorylation|cellular response to insulin stimulus|negative regulation of nucleic acid-templated transcription|transmembrane receptor protein tyrosine kinase signaling pathway|chordate embryonic development|positive regulation of phosphorylation|Fc receptor signaling pathway|regulation of phosphorylation|neurotrophin TRK receptor signaling pathway|transcription from RNA polymerase II promoter|transmembrane receptor protein serine/threonine kinase signaling pathway|phosphatidylinositol-mediated signaling|negative regulation of transcription from RNA polymerase II promoter|protein phosphorylation|Fc-epsilon receptor signaling pathway|insulin receptor signaling pathway|vascular endothelial growth factor receptor signaling pathway|nuclear import|ERBB signaling pathway|activin receptor signaling pathway|epidermal growth factor receptor signaling pathway" K04358 fibroblast growth factor[-] hsa05200|hsa04151|hsa04010|hsa04014|hsa04810|hsa04015|hsa05218 Pathways in cancer - Homo sapiens (human)|PI3K-Akt signaling pathway - Homo sapiens (human)|MAPK signaling pathway - Homo sapiens (human)|Ras signaling pathway - Homo sapiens (human)|Regulation of actin cytoskeleton - Homo sapiens (human)|Rap1 signaling pathway - Homo sapiens (human)|Melanoma - Homo sapiens (human) chr13:22245522-22278637 0.571735372 0.273414285 1.064258928 0.000338296 0.009184058 UP ENSG00000070985 TRPM5 "transient receptor potential cation channel, subfamily M, member 5 [Source:HGNC Symbol;Acc:HGNC:14323]" GO:0016020|GO:0005623|GO:0005215|GO:0009987|GO:0031224|GO:0022857|GO:0050794|GO:0071944|GO:0005886|GO:0055085|GO:0071804|GO:0022891|GO:0006810|GO:0016021|GO:0050877|GO:0043269|GO:0015075|GO:0006811|GO:0071805|GO:0034765|GO:0034220|GO:0007600|GO:0015267|GO:0005216|GO:0008324|GO:0006812|GO:0098655|GO:0007606|GO:0005261|GO:0050909|GO:0015672|GO:0005244|GO:0030001|GO:0022839|GO:0022890|GO:0006814|GO:0005272|GO:0070588|GO:0005267|GO:0046873|GO:0006813|GO:0005227|GO:0035725|GO:0006816|GO:0015081|GO:0015079 membrane|cell|transporter activity|cellular process|intrinsic component of membrane|transmembrane transporter activity|regulation of cellular process|cell periphery|plasma membrane|transmembrane transport|cellular potassium ion transport|substrate-specific transmembrane transporter activity|transport|integral component of membrane|neurological system process|regulation of ion transport|ion transmembrane transporter activity|ion transport|potassium ion transmembrane transport|regulation of ion transmembrane transport|ion transmembrane transport|sensory perception|channel activity|ion channel activity|cation transmembrane transporter activity|cation transport|cation transmembrane transport|sensory perception of chemical stimulus|cation channel activity|sensory perception of taste|monovalent inorganic cation transport|voltage-gated ion channel activity|metal ion transport|ion gated channel activity|inorganic cation transmembrane transporter activity|sodium ion transport|sodium channel activity|calcium ion transmembrane transport|potassium channel activity|metal ion transmembrane transporter activity|potassium ion transport|calcium activated cation channel activity|sodium ion transmembrane transport|calcium ion transport|sodium ion transmembrane transporter activity|potassium ion transmembrane transporter activity K04980 transient receptor potential cation channel subfamily M member 5[-] hsa04742 Taste transduction - Homo sapiens (human) chr11:2425745-2444275 0.586393051 0.199304193 1.556895949 0.000341333 0.009222926 UP ENSG00000095587 TLL2 tolloid like 2 [Source:HGNC Symbol;Acc:HGNC:11844] - - - - - - chr10:98124363-98273668 0.735173799 0.326061379 1.172941782 0.000341091 0.009222926 UP ENSG00000076344 RGS11 regulator of G-protein signaling 11 [Source:HGNC Symbol;Acc:HGNC:9993] GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0009987|GO:0008152|GO:0032991|GO:0005488|GO:0009893|GO:0023057|GO:0019898|GO:0005622|GO:0050794|GO:0051716|GO:0042995|GO:0071944|GO:0030234|GO:0005886|GO:0005515|GO:0019222|GO:0048523|GO:0043234|GO:0005834|GO:0044292|GO:0043005|GO:0005737|GO:0009968|GO:0019897|GO:0043085|GO:0009966|GO:0031234|GO:0031681|GO:0050790|GO:0008047|GO:0036477|GO:0007165|GO:0010646|GO:0007154|GO:0009898|GO:0023021|GO:0045744|GO:0007186|GO:0030425|GO:0030695|GO:0035556|GO:0051345|GO:0008277|GO:0005096|GO:0043087|GO:0043547|GO:0038032 signaling|membrane|cell|response to stimulus|signal transducer activity|cellular process|metabolic process|macromolecular complex|binding|positive regulation of metabolic process|negative regulation of signaling|extrinsic component of membrane|intracellular|regulation of cellular process|cellular response to stimulus|cell projection|cell periphery|enzyme regulator activity|plasma membrane|protein binding|regulation of metabolic process|negative regulation of cellular process|protein complex|heterotrimeric G-protein complex|dendrite terminus|neuron projection|cytoplasm|negative regulation of signal transduction|extrinsic component of plasma membrane|positive regulation of catalytic activity|regulation of signal transduction|extrinsic component of cytoplasmic side of plasma membrane|G-protein beta-subunit binding|regulation of catalytic activity|enzyme activator activity|somatodendritic compartment|signal transduction|regulation of cell communication|cell communication|cytoplasmic side of plasma membrane|termination of signal transduction|negative regulation of G-protein coupled receptor protein signaling pathway|G-protein coupled receptor signaling pathway|dendrite|GTPase regulator activity|intracellular signal transduction|positive regulation of hydrolase activity|regulation of G-protein coupled receptor protein signaling pathway|GTPase activator activity|regulation of GTPase activity|positive regulation of GTPase activity|termination of G-protein coupled receptor signaling pathway - - - - chr16:318300-325937 1.617335489 0.786687545 1.039756325 0.00036762 0.009762119 UP ENSG00000106809 OGN osteoglycin [Source:HGNC Symbol;Acc:HGNC:8126] GO:0005576|GO:0031012|GO:0005623|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0012505|GO:0008283|GO:0009056|GO:0005622|GO:0043229|GO:0044237|GO:0009405|GO:0050794|GO:0009058|GO:0006807|GO:0005515|GO:0048523|GO:0005615|GO:0043227|GO:0005578|GO:0071704|GO:0005102|GO:0008285|GO:0005737|GO:0044249|GO:0006082|GO:0043231|GO:0070062|GO:0005794|GO:0006790|GO:0042127|GO:0044281|GO:0031982|GO:0005975|GO:0048660|GO:0005796|GO:0048659|GO:0009059|GO:0042339|GO:0042340|GO:1901137|GO:0005773|GO:0008083|GO:0048662|GO:0005775|GO:0018146|GO:0043202|GO:0030203|GO:0006024|GO:0000323|GO:0005764|GO:0006027 extracellular region|extracellular matrix|cell|organelle|cellular process|metabolic process|binding|endomembrane system|cell proliferation|catabolic process|intracellular|intracellular organelle|cellular metabolic process|pathogenesis|regulation of cellular process|biosynthetic process|nitrogen compound metabolic process|protein binding|negative regulation of cellular process|extracellular space|membrane-bounded organelle|proteinaceous extracellular matrix|organic substance metabolic process|receptor binding|negative regulation of cell proliferation|cytoplasm|cellular biosynthetic process|organic acid metabolic process|intracellular membrane-bounded organelle|extracellular exosome|Golgi apparatus|sulfur compound metabolic process|regulation of cell proliferation|small molecule metabolic process|vesicle|carbohydrate metabolic process|regulation of smooth muscle cell proliferation|Golgi lumen|smooth muscle cell proliferation|macromolecule biosynthetic process|keratan sulfate metabolic process|keratan sulfate catabolic process|carbohydrate derivative biosynthetic process|vacuole|growth factor activity|negative regulation of smooth muscle cell proliferation|vacuolar lumen|keratan sulfate biosynthetic process|lysosomal lumen|glycosaminoglycan metabolic process|glycosaminoglycan biosynthetic process|lytic vacuole|lysosome|glycosaminoglycan catabolic process - - - - chr9:95146249-95166978 6.236031721 1.446780861 2.107781849 0.000401113 0.010372403 UP ENSG00000127928 GNGT1 "guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 [Source:HGNC Symbol;Acc:HGNC:4411]" GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0032991|GO:0005488|GO:0019898|GO:0031090|GO:0005622|GO:0048856|GO:0050794|GO:0051716|GO:0009605|GO:0005929|GO:0042995|GO:0006950|GO:0071944|GO:0016787|GO:0005886|GO:0005515|GO:0051606|GO:0009653|GO:0043234|GO:0043227|GO:0009628|GO:0016817|GO:0005834|GO:0048468|GO:0001750|GO:0033554|GO:0007267|GO:0072372|GO:0048731|GO:0007423|GO:0009582|GO:0019897|GO:0008104|GO:0060170|GO:0048869|GO:0031253|GO:0007275|GO:0009966|GO:0009314|GO:0031234|GO:0097381|GO:0008219|GO:0098588|GO:0009887|GO:0001666|GO:0048513|GO:0001917|GO:0007165|GO:0010646|GO:0007154|GO:0009898|GO:0022400|GO:0031513|GO:0030154|GO:0009416|GO:0071456|GO:0048666|GO:0007399|GO:0007186|GO:0007602|GO:0001654|GO:0071453|GO:0008277|GO:0016818|GO:0009583|GO:0012501|GO:0022008|GO:0016056|GO:0036294|GO:0042461|GO:0006915|GO:0071482|GO:0007603|GO:0030182|GO:0048592|GO:0016462|GO:0009584|GO:0010657|GO:0042462|GO:0048699|GO:0007268|GO:0001754|GO:0017111|GO:0003924|GO:0010659 "signaling|membrane|cell|response to stimulus|signal transducer activity|catalytic activity|organelle|cellular process|metabolic process|developmental process|macromolecular complex|binding|extrinsic component of membrane|organelle membrane|intracellular|anatomical structure development|regulation of cellular process|cellular response to stimulus|response to external stimulus|cilium|cell projection|response to stress|cell periphery|hydrolase activity|plasma membrane|protein binding|detection of stimulus|anatomical structure morphogenesis|protein complex|membrane-bounded organelle|response to abiotic stimulus|hydrolase activity, acting on acid anhydrides|heterotrimeric G-protein complex|cell development|photoreceptor outer segment|cellular response to stress|cell-cell signaling|primary cilium|system development|sensory organ development|detection of abiotic stimulus|extrinsic component of plasma membrane|protein localization|ciliary membrane|cellular developmental process|cell projection membrane|multicellular organism development|regulation of signal transduction|response to radiation|extrinsic component of cytoplasmic side of plasma membrane|photoreceptor disc membrane|cell death|bounding membrane of organelle|organ morphogenesis|response to hypoxia|animal organ development|photoreceptor inner segment|signal transduction|regulation of cell communication|cell communication|cytoplasmic side of plasma membrane|regulation of rhodopsin mediated signaling pathway|nonmotile primary cilium|cell differentiation|response to light stimulus|cellular response to hypoxia|neuron development|nervous system development|G-protein coupled receptor signaling pathway|phototransduction|eye development|cellular response to oxygen levels|regulation of G-protein coupled receptor protein signaling pathway|hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides|detection of light stimulus|programmed cell death|neurogenesis|rhodopsin mediated signaling pathway|cellular response to decreased oxygen levels|photoreceptor cell development|apoptotic process|cellular response to light stimulus|phototransduction, visible light|neuron differentiation|eye morphogenesis|pyrophosphatase activity|detection of visible light|muscle cell apoptotic process|eye photoreceptor cell development|generation of neurons|synaptic transmission|eye photoreceptor cell differentiation|nucleoside-triphosphatase activity|GTPase activity|cardiac muscle cell apoptotic process" K04548 guanine nucleotide-binding protein G(T) subunit gamma-T1[-] hsa05200|hsa04151|hsa04014|hsa04062|hsa05034|hsa04728|hsa04724|hsa04726|hsa04725|hsa04723|hsa04713|hsa05032|hsa04727|hsa04744 Pathways in cancer - Homo sapiens (human)|PI3K-Akt signaling pathway - Homo sapiens (human)|Ras signaling pathway - Homo sapiens (human)|Chemokine signaling pathway - Homo sapiens (human)|Alcoholism - Homo sapiens (human)|Dopaminergic synapse - Homo sapiens (human)|Glutamatergic synapse - Homo sapiens (human)|Serotonergic synapse - Homo sapiens (human)|Cholinergic synapse - Homo sapiens (human)|Retrograde endocannabinoid signaling - Homo sapiens (human)|Circadian entrainment - Homo sapiens (human)|Morphine addiction - Homo sapiens (human)|GABAergic synapse - Homo sapiens (human)|Phototransduction - Homo sapiens (human) chr7:93220885-93540577 0.233829696 0.075562756 1.629710933 0.000412262 0.01057825 UP ENSG00000184985 SORCS2 sortilin-related VPS10 domain containing receptor 2 [Source:HGNC Symbol;Acc:HGNC:16698] GO:0023052|GO:0016020|GO:0050896|GO:0004871|GO:0009987|GO:0005488|GO:0038023|GO:0031224|GO:0050794|GO:0051716|GO:0005515|GO:0004872|GO:0004888|GO:0016021|GO:0007165|GO:0007154|GO:0007186|GO:0008528|GO:0004930|GO:0007218|GO:0008188 signaling|membrane|response to stimulus|signal transducer activity|cellular process|binding|signaling receptor activity|intrinsic component of membrane|regulation of cellular process|cellular response to stimulus|protein binding|receptor activity|transmembrane signaling receptor activity|integral component of membrane|signal transduction|cell communication|G-protein coupled receptor signaling pathway|G-protein coupled peptide receptor activity|G-protein coupled receptor activity|neuropeptide signaling pathway|neuropeptide receptor activity - - - - chr4:7194265-7744554 1.26005676 0.484249294 1.379666873 0.000421038 0.010760654 UP ENSG00000173114 LRRN3 leucine rich repeat neuronal 3 [Source:HGNC Symbol;Acc:HGNC:17200] - - - - - - chr7:110731062-110765510 1.138180435 0.30650799 1.892732699 0.000441356 0.011221419 UP ENSG00000144407 PTH2R parathyroid hormone 2 receptor [Source:HGNC Symbol;Acc:HGNC:9609] GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0009987|GO:0005488|GO:0038023|GO:0031224|GO:0050794|GO:0051716|GO:0071944|GO:0005886|GO:0005515|GO:0004872|GO:0004888|GO:0031226|GO:0016021|GO:0005887|GO:0007165|GO:0007154|GO:0007186|GO:0004930|GO:0007166|GO:0004991 signaling|membrane|cell|response to stimulus|signal transducer activity|cellular process|binding|signaling receptor activity|intrinsic component of membrane|regulation of cellular process|cellular response to stimulus|cell periphery|plasma membrane|protein binding|receptor activity|transmembrane signaling receptor activity|intrinsic component of plasma membrane|integral component of membrane|integral component of plasma membrane|signal transduction|cell communication|G-protein coupled receptor signaling pathway|G-protein coupled receptor activity|cell surface receptor signaling pathway|parathyroid hormone receptor activity K04586 parathyroid hormone receptor 2[-] hsa04080 Neuroactive ligand-receptor interaction - Homo sapiens (human) chr2:209271556-209359231 0.228844681 0.03857294 2.568707748 0.000445577 0.011254409 UP ENSG00000170370 EMX2 empty spiracles homeobox 2 [Source:HGNC Symbol;Acc:HGNC:3341] GO:0040011|GO:0005623|GO:0050896|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0048870|GO:0008283|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0050794|GO:0009058|GO:0006807|GO:0097159|GO:0005515|GO:0019222|GO:0043227|GO:0071704|GO:0007389|GO:0007420|GO:0021766|GO:0021987|GO:0048731|GO:1901360|GO:0016477|GO:0021537|GO:0044249|GO:0006139|GO:0048869|GO:0007275|GO:0043231|GO:0034641|GO:0006928|GO:0006725|GO:0030900|GO:0021542|GO:0061351|GO:0003676|GO:0046483|GO:0031323|GO:0048513|GO:0042493|GO:0021543|GO:0060322|GO:0010468|GO:0005634|GO:0007417|GO:0030154|GO:0072001|GO:0021796|GO:0009059|GO:0007399|GO:0003677|GO:0051252|GO:0003002|GO:0021871|GO:0034645|GO:0010467|GO:0021761|GO:0021846|GO:0016070|GO:0021885|GO:0021978|GO:0001655|GO:0022008|GO:0032774|GO:0006351|GO:0006355|GO:0043565|GO:0030182|GO:0009952|GO:2001141|GO:1903506|GO:0048699 "locomotion|cell|response to stimulus|organelle|cellular process|metabolic process|developmental process|binding|cell motility|cell proliferation|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|regulation of cellular process|biosynthetic process|nitrogen compound metabolic process|organic cyclic compound binding|protein binding|regulation of metabolic process|membrane-bounded organelle|organic substance metabolic process|pattern specification process|brain development|hippocampus development|cerebral cortex development|system development|organic cyclic compound metabolic process|cell migration|telencephalon development|cellular biosynthetic process|nucleobase-containing compound metabolic process|cellular developmental process|multicellular organism development|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|movement of cell or subcellular component|cellular aromatic compound metabolic process|forebrain development|dentate gyrus development|neural precursor cell proliferation|nucleic acid binding|heterocycle metabolic process|regulation of cellular metabolic process|animal organ development|response to drug|pallium development|head development|regulation of gene expression|nucleus|central nervous system development|cell differentiation|renal system development|cerebral cortex regionalization|macromolecule biosynthetic process|nervous system development|DNA binding|regulation of RNA metabolic process|regionalization|forebrain regionalization|cellular macromolecule biosynthetic process|gene expression|limbic system development|cell proliferation in forebrain|RNA metabolic process|forebrain cell migration|telencephalon regionalization|urogenital system development|neurogenesis|RNA biosynthetic process|transcription, DNA-templated|regulation of transcription, DNA-templated|sequence-specific DNA binding|neuron differentiation|anterior/posterior pattern specification|regulation of RNA biosynthetic process|regulation of nucleic acid-templated transcription|generation of neurons" - - - - chr10:119301955-119309056 0.692682535 0.306402812 1.176764764 0.000454203 0.011371823 UP ENSG00000248869 RP11-138I17.1 - - - - - - - chr4:137717877-138133953 0.352982461 0.072891121 2.275781501 0.000461283 0.011460153 UP ENSG00000197769 MAP1LC3C microtubule associated protein 1 light chain 3 gamma [Source:HGNC Symbol;Acc:HGNC:13353] GO:0016020|GO:0005623|GO:0050896|GO:0043226|GO:0009987|GO:0008152|GO:0032991|GO:0005488|GO:0012505|GO:0019898|GO:0031090|GO:0009056|GO:0005622|GO:0043229|GO:0016043|GO:0051716|GO:0009605|GO:0006950|GO:0005515|GO:0043234|GO:0043227|GO:0006914|GO:0016236|GO:0008092|GO:0033554|GO:0005774|GO:0032403|GO:0005737|GO:0022607|GO:0043231|GO:0009991|GO:0098588|GO:0005874|GO:0042594|GO:0061024|GO:0031668|GO:0031982|GO:0044804|GO:0006996|GO:0000422|GO:0007154|GO:0008017|GO:0005829|GO:0000045|GO:0061025|GO:0000421|GO:0009267|GO:0031410|GO:1903008|GO:0031669|GO:0015631|GO:0007033|GO:0031667|GO:0070925|GO:0007005|GO:0005773|GO:0000407|GO:0005856|GO:0005776|GO:0006995|GO:0015630 membrane|cell|response to stimulus|organelle|cellular process|metabolic process|macromolecular complex|binding|endomembrane system|extrinsic component of membrane|organelle membrane|catabolic process|intracellular|intracellular organelle|cellular component organization|cellular response to stimulus|response to external stimulus|response to stress|protein binding|protein complex|membrane-bounded organelle|autophagy|macroautophagy|cytoskeletal protein binding|cellular response to stress|vacuolar membrane|protein complex binding|cytoplasm|cellular component assembly|intracellular membrane-bounded organelle|response to extracellular stimulus|bounding membrane of organelle|microtubule|response to starvation|membrane organization|cellular response to extracellular stimulus|vesicle|nucleophagy|organelle organization|mitophagy|cell communication|microtubule binding|cytosol|autophagosome assembly|membrane fusion|autophagosome membrane|cellular response to starvation|cytoplasmic vesicle|organelle disassembly|cellular response to nutrient levels|tubulin binding|vacuole organization|response to nutrient levels|organelle assembly|mitochondrion organization|vacuole|pre-autophagosomal structure|cytoskeleton|autophagosome|cellular response to nitrogen starvation|microtubule cytoskeleton - - - - chr1:242158792-242162375 3.350737926 1.283839388 1.384014124 0.000482772 0.011834562 UP ENSG00000106538 RARRES2 retinoic acid receptor responder (tazarotene induced) 2 [Source:HGNC Symbol;Acc:HGNC:9868] - - - - - - chr7:150035408-150038763 15.19470796 7.209273005 1.075643259 0.00048604 0.011880826 UP ENSG00000162706 CADM3 cell adhesion molecule 3 [Source:HGNC Symbol;Acc:HGNC:17601] - - K06780 cell adhesion molecule 3[-] - - chr1:159141399-159173103 2.780120659 1.064008094 1.385638373 0.000487683 0.01190971 UP ENSG00000223764 RP11-54O7.3 - - - - - - - chr1:852250-855072 2.575821367 1.215825324 1.083096573 0.000495003 0.012042905 UP ENSG00000167483 FAM129C family with sequence similarity 129 member C [Source:HGNC Symbol;Acc:HGNC:24130] - - - - - - chr19:17634110-17664648 0.577712535 0.126759493 2.188257999 0.000518563 0.0125156 UP ENSG00000255021 RP11-536I6.2 - - - - - - - chr3:14313873-14345345 4.106106799 1.288258804 1.672348701 0.000518359 0.0125156 UP ENSG00000167244 IGF2 insulin like growth factor 2 [Source:HGNC Symbol;Acc:HGNC:5466] - - K13769 insulin-like growth factor 2[-] hsa05205 Proteoglycans in cancer - Homo sapiens (human) chr11:2150342-2170833 8.131809152 3.764530417 1.111106441 0.000524952 0.012586864 UP ENSG00000102109 PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor [Source:HGNC Symbol;Acc:HGNC:17301] GO:0023052|GO:0005576|GO:0005623|GO:0050896|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0012505|GO:0005622|GO:0043229|GO:0044237|GO:0050794|GO:0051716|GO:0009605|GO:0042445|GO:0006950|GO:0006807|GO:0030234|GO:0005515|GO:0019222|GO:0009892|GO:0048523|GO:0005615|GO:0043227|GO:0009628|GO:0071704|GO:0010817|GO:0044092|GO:0005102|GO:0002021|GO:0043086|GO:0005737|GO:0043231|GO:0070062|GO:0034641|GO:0005794|GO:0050790|GO:0009991|GO:0009266|GO:0019538|GO:0031324|GO:0016486|GO:0031323|GO:0031982|GO:0004857|GO:0007165|GO:0009409|GO:0007154|GO:0030141|GO:0051248|GO:0032269|GO:0005802|GO:0006518|GO:0051604|GO:0044267|GO:0030414|GO:0051346|GO:0007186|GO:0031410|GO:0006508|GO:0031667|GO:0051246|GO:0010467|GO:0043603|GO:0032268|GO:0016023|GO:0031988|GO:0007218|GO:0052547|GO:0030162|GO:0004866|GO:0010466|GO:0045861|GO:0016485|GO:0004867|GO:0010951|GO:0052548 "signaling|extracellular region|cell|response to stimulus|organelle|cellular process|metabolic process|binding|endomembrane system|intracellular|intracellular organelle|cellular metabolic process|regulation of cellular process|cellular response to stimulus|response to external stimulus|hormone metabolic process|response to stress|nitrogen compound metabolic process|enzyme regulator activity|protein binding|regulation of metabolic process|negative regulation of metabolic process|negative regulation of cellular process|extracellular space|membrane-bounded organelle|response to abiotic stimulus|organic substance metabolic process|regulation of hormone levels|negative regulation of molecular function|receptor binding|response to dietary excess|negative regulation of catalytic activity|cytoplasm|intracellular membrane-bounded organelle|extracellular exosome|cellular nitrogen compound metabolic process|Golgi apparatus|regulation of catalytic activity|response to extracellular stimulus|response to temperature stimulus|protein metabolic process|negative regulation of cellular metabolic process|peptide hormone processing|regulation of cellular metabolic process|vesicle|enzyme inhibitor activity|signal transduction|response to cold|cell communication|secretory granule|negative regulation of protein metabolic process|negative regulation of cellular protein metabolic process|trans-Golgi network|peptide metabolic process|protein maturation|cellular protein metabolic process|peptidase inhibitor activity|negative regulation of hydrolase activity|G-protein coupled receptor signaling pathway|cytoplasmic vesicle|proteolysis|response to nutrient levels|regulation of protein metabolic process|gene expression|cellular amide metabolic process|regulation of cellular protein metabolic process|cytoplasmic, membrane-bounded vesicle|membrane-bounded vesicle|neuropeptide signaling pathway|regulation of peptidase activity|regulation of proteolysis|endopeptidase inhibitor activity|negative regulation of peptidase activity|negative regulation of proteolysis|protein processing|serine-type endopeptidase inhibitor activity|negative regulation of endopeptidase activity|regulation of endopeptidase activity" - - - - chrX:48689504-48694035 9.969380522 1.990431144 2.324422897 0.000533648 0.012742879 UP ENSG00000165084 C8orf34 chromosome 8 open reading frame 34 [Source:HGNC Symbol;Acc:HGNC:30905] - - - - - - chr8:69242957-69731257 0.078717351 0.023320388 1.755089883 0.000544589 0.01289629 UP ENSG00000166856 GPR182 G protein-coupled receptor 182 [Source:HGNC Symbol;Acc:HGNC:13708] GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0009987|GO:0038023|GO:0031224|GO:0050794|GO:0051716|GO:0006950|GO:0071944|GO:0005886|GO:0004872|GO:0009628|GO:0004888|GO:0016021|GO:0001666|GO:0007165|GO:0007154|GO:0007186|GO:0008528|GO:0004930|GO:0007166|GO:0001605 signaling|membrane|cell|response to stimulus|signal transducer activity|cellular process|signaling receptor activity|intrinsic component of membrane|regulation of cellular process|cellular response to stimulus|response to stress|cell periphery|plasma membrane|receptor activity|response to abiotic stimulus|transmembrane signaling receptor activity|integral component of membrane|response to hypoxia|signal transduction|cell communication|G-protein coupled receptor signaling pathway|G-protein coupled peptide receptor activity|G-protein coupled receptor activity|cell surface receptor signaling pathway|adrenomedullin receptor activity - - - - chr12:57388230-57390468 0.440992553 0.150809874 1.548023405 0.000574924 0.013454673 UP ENSG00000198597 ZNF536 zinc finger protein 536 [Source:HGNC Symbol;Acc:HGNC:29025] GO:0001071|GO:0023052|GO:0005623|GO:0050896|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0023057|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0050794|GO:0009058|GO:0051716|GO:0043167|GO:0003700|GO:0006807|GO:0097159|GO:0019222|GO:0050793|GO:0009892|GO:0048523|GO:0043227|GO:0071704|GO:0045596|GO:0048468|GO:0000981|GO:0048731|GO:1901360|GO:0045595|GO:0009968|GO:0044249|GO:0006139|GO:0048869|GO:0007275|GO:0009966|GO:0043231|GO:0034641|GO:0006725|GO:0009890|GO:0031324|GO:0003676|GO:0043169|GO:0046483|GO:0031323|GO:0007165|GO:0010646|GO:0007154|GO:0048385|GO:0010468|GO:0005634|GO:0030154|GO:0048387|GO:0010629|GO:0009059|GO:0007399|GO:0050768|GO:0003677|GO:0051252|GO:0051960|GO:0000982|GO:0046872|GO:0034645|GO:0030522|GO:0010467|GO:0001227|GO:0016070|GO:0010721|GO:0022008|GO:0032774|GO:0006351|GO:0045892|GO:0050767|GO:0006355|GO:0000975|GO:1902679|GO:0045665|GO:0043565|GO:0001078|GO:0030182|GO:0003690|GO:2001141|GO:0048384|GO:0006357|GO:1903506|GO:0048699|GO:1903507|GO:0044212|GO:0006366|GO:0000122|GO:0045664|GO:0044323|GO:0001012|GO:0001159|GO:0000976|GO:0000977|GO:0000987|GO:0000978 "nucleic acid binding transcription factor activity|signaling|cell|response to stimulus|organelle|cellular process|metabolic process|developmental process|binding|negative regulation of signaling|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|regulation of cellular process|biosynthetic process|cellular response to stimulus|ion binding|transcription factor activity, sequence-specific DNA binding|nitrogen compound metabolic process|organic cyclic compound binding|regulation of metabolic process|regulation of developmental process|negative regulation of metabolic process|negative regulation of cellular process|membrane-bounded organelle|organic substance metabolic process|negative regulation of cell differentiation|cell development|RNA polymerase II transcription factor activity, sequence-specific DNA binding|system development|organic cyclic compound metabolic process|regulation of cell differentiation|negative regulation of signal transduction|cellular biosynthetic process|nucleobase-containing compound metabolic process|cellular developmental process|multicellular organism development|regulation of signal transduction|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|cellular aromatic compound metabolic process|negative regulation of biosynthetic process|negative regulation of cellular metabolic process|nucleic acid binding|cation binding|heterocycle metabolic process|regulation of cellular metabolic process|signal transduction|regulation of cell communication|cell communication|regulation of retinoic acid receptor signaling pathway|regulation of gene expression|nucleus|cell differentiation|negative regulation of retinoic acid receptor signaling pathway|negative regulation of gene expression|macromolecule biosynthetic process|nervous system development|negative regulation of neurogenesis|DNA binding|regulation of RNA metabolic process|regulation of nervous system development|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding|metal ion binding|cellular macromolecule biosynthetic process|intracellular receptor signaling pathway|gene expression|transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding|RNA metabolic process|negative regulation of cell development|neurogenesis|RNA biosynthetic process|transcription, DNA-templated|negative regulation of transcription, DNA-templated|regulation of neurogenesis|regulation of transcription, DNA-templated|regulatory region DNA binding|negative regulation of RNA biosynthetic process|negative regulation of neuron differentiation|sequence-specific DNA binding|transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding|neuron differentiation|double-stranded DNA binding|regulation of RNA biosynthetic process|retinoic acid receptor signaling pathway|regulation of transcription from RNA polymerase II promoter|regulation of nucleic acid-templated transcription|generation of neurons|negative regulation of nucleic acid-templated transcription|transcription regulatory region DNA binding|transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|regulation of neuron differentiation|retinoic acid-responsive element binding|RNA polymerase II regulatory region DNA binding|core promoter proximal region DNA binding|transcription regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding" - - - - chr19:30719421-31204445 0.374309223 0.167728185 1.158105457 0.000579494 0.013500444 UP ENSG00000137766 UNC13C unc-13 homolog C (C. elegans) [Source:HGNC Symbol;Acc:HGNC:23149] GO:0023052|GO:0016020|GO:0005623|GO:0030054|GO:0050896|GO:0009987|GO:0045202|GO:0005488|GO:0048786|GO:0097060|GO:0005622|GO:0050794|GO:0051716|GO:0043167|GO:0071944|GO:0005886|GO:0005515|GO:0008289|GO:0007267|GO:0005737|GO:0019992|GO:0042734|GO:0006810|GO:0032940|GO:0043169|GO:0007165|GO:0007154|GO:0006887|GO:0046903|GO:0016192|GO:0046872|GO:0035556|GO:0007268 signaling|membrane|cell|cell junction|response to stimulus|cellular process|synapse|binding|presynaptic active zone|synaptic membrane|intracellular|regulation of cellular process|cellular response to stimulus|ion binding|cell periphery|plasma membrane|protein binding|lipid binding|cell-cell signaling|cytoplasm|diacylglycerol binding|presynaptic membrane|transport|secretion by cell|cation binding|signal transduction|cell communication|exocytosis|secretion|vesicle-mediated transport|metal ion binding|intracellular signal transduction|synaptic transmission K15293 protein unc-13 A/B/C[-] hsa04721 Synaptic vesicle cycle - Homo sapiens (human) chr15:54305101-54920806 0.0626265 0.014488271 2.111887809 0.000688189 0.015287622 UP ENSG00000237923 XXbac-BPG27H4.8 - - - - - - - chr6:30807303-30815936 0.818396163 0.297784672 1.458529887 0.000708309 0.015600323 UP ENSG00000205837 LINC00487 long intergenic non-protein coding RNA 487 [Source:HGNC Symbol;Acc:HGNC:42947] - - - - - - chr2:6868309-6910442 0.334567415 0.074923004 2.1588163 0.000709738 0.015618481 UP ENSG00000255026 RP11-326C3.2 - - - - - - - chr11:287305-288987 2.70482679 1.190433366 1.184049342 0.000725812 0.015870043 UP ENSG00000166736 HTR3A "5-hydroxytryptamine (serotonin) receptor 3A, ionotropic [Source:HGNC Symbol;Acc:HGNC:5297]" GO:0023052|GO:0016020|GO:0005623|GO:0030054|GO:0050896|GO:0004871|GO:0005215|GO:0009987|GO:0045202|GO:0005488|GO:0038023|GO:0031224|GO:0097060|GO:0005622|GO:0022857|GO:0050794|GO:0051716|GO:0043167|GO:0042995|GO:0097159|GO:0071944|GO:0005886|GO:0043176|GO:0044297|GO:0004872|GO:0010033|GO:0010243|GO:0004888|GO:0055085|GO:0071804|GO:0007267|GO:0045211|GO:0022891|GO:0043005|GO:0005737|GO:0051378|GO:0007586|GO:0031226|GO:0006810|GO:0016021|GO:0005887|GO:0043169|GO:0036477|GO:0007165|GO:0043025|GO:0007154|GO:0070848|GO:0015075|GO:0006811|GO:0060359|GO:0071805|GO:0007186|GO:0014070|GO:0034220|GO:0030424|GO:0004930|GO:0043279|GO:0015267|GO:0042220|GO:0071310|GO:0005216|GO:0071363|GO:0008227|GO:0007210|GO:0045471|GO:0015276|GO:0008324|GO:0006812|GO:0098655|GO:0004993|GO:0005261|GO:0015672|GO:0007268|GO:0005244|GO:0005230|GO:0030001|GO:0022890|GO:0022843|GO:0005267|GO:0046873|GO:0005232|GO:0006813|GO:0005231|GO:0005249|GO:0015079 signaling|membrane|cell|cell junction|response to stimulus|signal transducer activity|transporter activity|cellular process|synapse|binding|signaling receptor activity|intrinsic component of membrane|synaptic membrane|intracellular|transmembrane transporter activity|regulation of cellular process|cellular response to stimulus|ion binding|cell projection|organic cyclic compound binding|cell periphery|plasma membrane|amine binding|cell body|receptor activity|response to organic substance|response to organonitrogen compound|transmembrane signaling receptor activity|transmembrane transport|cellular potassium ion transport|cell-cell signaling|postsynaptic membrane|substrate-specific transmembrane transporter activity|neuron projection|cytoplasm|serotonin binding|digestion|intrinsic component of plasma membrane|transport|integral component of membrane|integral component of plasma membrane|cation binding|somatodendritic compartment|signal transduction|neuronal cell body|cell communication|response to growth factor|ion transmembrane transporter activity|ion transport|response to ammonium ion|potassium ion transmembrane transport|G-protein coupled receptor signaling pathway|response to organic cyclic compound|ion transmembrane transport|axon|G-protein coupled receptor activity|response to alkaloid|channel activity|response to cocaine|cellular response to organic substance|ion channel activity|cellular response to growth factor stimulus|G-protein coupled amine receptor activity|serotonin receptor signaling pathway|response to ethanol|ligand-gated ion channel activity|cation transmembrane transporter activity|cation transport|cation transmembrane transport|G-protein coupled serotonin receptor activity|cation channel activity|monovalent inorganic cation transport|synaptic transmission|voltage-gated ion channel activity|extracellular ligand-gated ion channel activity|metal ion transport|inorganic cation transmembrane transporter activity|voltage-gated cation channel activity|potassium channel activity|metal ion transmembrane transporter activity|serotonin-activated cation-selective channel activity|potassium ion transport|excitatory extracellular ligand-gated ion channel activity|voltage-gated potassium channel activity|potassium ion transmembrane transporter activity K04819 5-hydroxytryptamine receptor 3[-] hsa04726|hsa04742 Serotonergic synapse - Homo sapiens (human)|Taste transduction - Homo sapiens (human) chr11:113845603-113861035 0.046928559 0.002757437 4.089066086 0.000776552 0.016746151 UP ENSG00000162761 LMX1A "LIM homeobox transcription factor 1, alpha [Source:HGNC Symbol;Acc:HGNC:6653]" GO:0040011|GO:0005623|GO:0050896|GO:0040007|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0040008|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0016043|GO:0050794|GO:0009058|GO:0009605|GO:0043167|GO:0006807|GO:0097159|GO:0009653|GO:0019222|GO:0050793|GO:0048523|GO:0016049|GO:0043227|GO:0071704|GO:0051128|GO:0007420|GO:0045596|GO:0048468|GO:0030030|GO:0021766|GO:0048731|GO:1901360|GO:0045595|GO:0021537|GO:0044249|GO:0006139|GO:0048869|GO:0007275|GO:0043231|GO:0034641|GO:0006928|GO:0006725|GO:0030900|GO:0022037|GO:0021542|GO:0030901|GO:0003676|GO:0043169|GO:0046483|GO:0006935|GO:0031323|GO:0048513|GO:0001558|GO:0030902|GO:0021543|GO:0021549|GO:0060322|GO:0010468|GO:0005634|GO:0007417|GO:0030154|GO:0048666|GO:0009059|GO:0007399|GO:0000902|GO:0032990|GO:0050768|GO:0003677|GO:0051252|GO:0051960|GO:0048858|GO:0000904|GO:0046872|GO:0031175|GO:0034645|GO:0010467|GO:0021761|GO:0016070|GO:0010721|GO:0022008|GO:0032774|GO:0061564|GO:0006351|GO:0007411|GO:0048667|GO:0046914|GO:0048812|GO:0050767|GO:0006355|GO:0045665|GO:0043565|GO:0030182|GO:2001141|GO:0021953|GO:1903506|GO:0007409|GO:0048699|GO:0071542|GO:0008270|GO:0045664 "locomotion|cell|response to stimulus|growth|organelle|cellular process|metabolic process|developmental process|binding|regulation of growth|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|cellular component organization|regulation of cellular process|biosynthetic process|response to external stimulus|ion binding|nitrogen compound metabolic process|organic cyclic compound binding|anatomical structure morphogenesis|regulation of metabolic process|regulation of developmental process|negative regulation of cellular process|cell growth|membrane-bounded organelle|organic substance metabolic process|regulation of cellular component organization|brain development|negative regulation of cell differentiation|cell development|cell projection organization|hippocampus development|system development|organic cyclic compound metabolic process|regulation of cell differentiation|telencephalon development|cellular biosynthetic process|nucleobase-containing compound metabolic process|cellular developmental process|multicellular organism development|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|movement of cell or subcellular component|cellular aromatic compound metabolic process|forebrain development|metencephalon development|dentate gyrus development|midbrain development|nucleic acid binding|cation binding|heterocycle metabolic process|chemotaxis|regulation of cellular metabolic process|animal organ development|regulation of cell growth|hindbrain development|pallium development|cerebellum development|head development|regulation of gene expression|nucleus|central nervous system development|cell differentiation|neuron development|macromolecule biosynthetic process|nervous system development|cell morphogenesis|cell part morphogenesis|negative regulation of neurogenesis|DNA binding|regulation of RNA metabolic process|regulation of nervous system development|cell projection morphogenesis|cell morphogenesis involved in differentiation|metal ion binding|neuron projection development|cellular macromolecule biosynthetic process|gene expression|limbic system development|RNA metabolic process|negative regulation of cell development|neurogenesis|RNA biosynthetic process|axon development|transcription, DNA-templated|axon guidance|cell morphogenesis involved in neuron differentiation|transition metal ion binding|neuron projection morphogenesis|regulation of neurogenesis|regulation of transcription, DNA-templated|negative regulation of neuron differentiation|sequence-specific DNA binding|neuron differentiation|regulation of RNA biosynthetic process|central nervous system neuron differentiation|regulation of nucleic acid-templated transcription|axonogenesis|generation of neurons|dopaminergic neuron differentiation|zinc ion binding|regulation of neuron differentiation" - - - - chr1:165171104-165325952 0.204485257 0.053581254 1.932196579 0.000791099 0.016960653 UP ENSG00000115041 KCNIP3 Kv channel interacting protein 3 [Source:HGNC Symbol;Acc:HGNC:15523] GO:0001071|GO:0023052|GO:0005576|GO:0016020|GO:0031012|GO:0005623|GO:0050896|GO:0005215|GO:0007610|GO:0043226|GO:0009987|GO:0000988|GO:0008152|GO:0032991|GO:0005488|GO:0012505|GO:0031224|GO:0005622|GO:0043229|GO:0044237|GO:0022857|GO:0016043|GO:0050794|GO:0009058|GO:0051716|GO:0043167|GO:0051641|GO:0006950|GO:0003700|GO:0000989|GO:0006807|GO:0097159|GO:0071944|GO:0005886|GO:0005515|GO:0044708|GO:0019222|GO:0016247|GO:0009892|GO:0048523|GO:0043234|GO:0043227|GO:0005578|GO:0071704|GO:0055085|GO:0071804|GO:0022891|GO:0000981|GO:1901360|GO:0005737|GO:0044249|GO:0031226|GO:0006139|GO:0008104|GO:0010256|GO:0043231|GO:0034641|GO:0005794|GO:0006810|GO:0006725|GO:0016021|GO:0009890|GO:0005887|GO:0008219|GO:0008022|GO:1902495|GO:0048306|GO:0031324|GO:0061024|GO:0003676|GO:0043169|GO:0048266|GO:0015459|GO:0005783|GO:0046483|GO:0031323|GO:0003712|GO:0050877|GO:0007165|GO:0033555|GO:0007154|GO:0010941|GO:0003714|GO:0005829|GO:0043269|GO:0034702|GO:0010468|GO:0034613|GO:0005634|GO:0015075|GO:1901214|GO:0006811|GO:0008076|GO:0010629|GO:0009059|GO:0048265|GO:0071805|GO:0003677|GO:0043067|GO:0051252|GO:0000982|GO:0034765|GO:0046872|GO:0034220|GO:0007600|GO:0034645|GO:0010467|GO:0072657|GO:0001227|GO:0007009|GO:0016070|GO:0012501|GO:0015267|GO:0070997|GO:0051402|GO:0005216|GO:0032774|GO:0006351|GO:0045892|GO:0043523|GO:0006355|GO:0008324|GO:0006915|GO:0000975|GO:1902679|GO:0042981|GO:1901379|GO:0072659|GO:0043565|GO:0001078|GO:0006812|GO:0098655|GO:0034703|GO:0003690|GO:0005509|GO:0019233|GO:2001141|GO:0005261|GO:0006357|GO:1903506|GO:0015672|GO:1903507|GO:0044212|GO:0034705|GO:0005244|GO:0006366|GO:0000122|GO:0030001|GO:0043266|GO:0022890|GO:0001012|GO:0005267|GO:0046873|GO:0006813|GO:0001159|GO:0000976|GO:0000977|GO:0000987|GO:0015079|GO:0000978 "nucleic acid binding transcription factor activity|signaling|extracellular region|membrane|extracellular matrix|cell|response to stimulus|transporter activity|behavior|organelle|cellular process|transcription factor activity, protein binding|metabolic process|macromolecular complex|binding|endomembrane system|intrinsic component of membrane|intracellular|intracellular organelle|cellular metabolic process|transmembrane transporter activity|cellular component organization|regulation of cellular process|biosynthetic process|cellular response to stimulus|ion binding|cellular localization|response to stress|transcription factor activity, sequence-specific DNA binding|transcription factor activity, transcription factor binding|nitrogen compound metabolic process|organic cyclic compound binding|cell periphery|plasma membrane|protein binding|single-organism behavior|regulation of metabolic process|channel regulator activity|negative regulation of metabolic process|negative regulation of cellular process|protein complex|membrane-bounded organelle|proteinaceous extracellular matrix|organic substance metabolic process|transmembrane transport|cellular potassium ion transport|substrate-specific transmembrane transporter activity|RNA polymerase II transcription factor activity, sequence-specific DNA binding|organic cyclic compound metabolic process|cytoplasm|cellular biosynthetic process|intrinsic component of plasma membrane|nucleobase-containing compound metabolic process|protein localization|endomembrane system organization|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|Golgi apparatus|transport|cellular aromatic compound metabolic process|integral component of membrane|negative regulation of biosynthetic process|integral component of plasma membrane|cell death|protein C-terminus binding|transmembrane transporter complex|calcium-dependent protein binding|negative regulation of cellular metabolic process|membrane organization|nucleic acid binding|cation binding|behavioral response to pain|potassium channel regulator activity|endoplasmic reticulum|heterocycle metabolic process|regulation of cellular metabolic process|transcription cofactor activity|neurological system process|signal transduction|multicellular organismal response to stress|cell communication|regulation of cell death|transcription corepressor activity|cytosol|regulation of ion transport|ion channel complex|regulation of gene expression|cellular protein localization|nucleus|ion transmembrane transporter activity|regulation of neuron death|ion transport|voltage-gated potassium channel complex|negative regulation of gene expression|macromolecule biosynthetic process|response to pain|potassium ion transmembrane transport|DNA binding|regulation of programmed cell death|regulation of RNA metabolic process|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding|regulation of ion transmembrane transport|metal ion binding|ion transmembrane transport|sensory perception|cellular macromolecule biosynthetic process|gene expression|protein localization to membrane|transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding|plasma membrane organization|RNA metabolic process|programmed cell death|channel activity|neuron death|neuron apoptotic process|ion channel activity|RNA biosynthetic process|transcription, DNA-templated|negative regulation of transcription, DNA-templated|regulation of neuron apoptotic process|regulation of transcription, DNA-templated|cation transmembrane transporter activity|apoptotic process|regulatory region DNA binding|negative regulation of RNA biosynthetic process|regulation of apoptotic process|regulation of potassium ion transmembrane transport|protein localization to plasma membrane|sequence-specific DNA binding|transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding|cation transport|cation transmembrane transport|cation channel complex|double-stranded DNA binding|calcium ion binding|sensory perception of pain|regulation of RNA biosynthetic process|cation channel activity|regulation of transcription from RNA polymerase II promoter|regulation of nucleic acid-templated transcription|monovalent inorganic cation transport|negative regulation of nucleic acid-templated transcription|transcription regulatory region DNA binding|potassium channel complex|voltage-gated ion channel activity|transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|metal ion transport|regulation of potassium ion transport|inorganic cation transmembrane transporter activity|RNA polymerase II regulatory region DNA binding|potassium channel activity|metal ion transmembrane transporter activity|potassium ion transport|core promoter proximal region DNA binding|transcription regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|potassium ion transmembrane transporter activity|RNA polymerase II core promoter proximal region sequence-specific DNA binding" - - - - chr2:95963052-96051825 3.452785261 1.653582101 1.062165933 0.000858867 0.017907868 UP ENSG00000224201 PNMA6A - - - - - - - chrX:152240839-152340864 0.30858926 0.108788253 1.504165063 0.000890189 0.018294941 UP ENSG00000267121 CTD-2020K17.1 - - - - - - - chr17:43268298-43299589 2.759120763 1.242802355 1.150611722 0.000899748 0.018447326 UP ENSG00000116176 TPSG1 tryptase gamma 1 [Source:HGNC Symbol;Acc:HGNC:14134] GO:0016020|GO:0005623|GO:0003824|GO:0008152|GO:0031224|GO:0071944|GO:0016787|GO:0005886|GO:0071704|GO:0008233|GO:0031226|GO:0017171|GO:0016021|GO:0005887|GO:0019538|GO:0008236|GO:0006508|GO:0004252|GO:0004175 membrane|cell|catalytic activity|metabolic process|intrinsic component of membrane|cell periphery|hydrolase activity|plasma membrane|organic substance metabolic process|peptidase activity|intrinsic component of plasma membrane|serine hydrolase activity|integral component of membrane|integral component of plasma membrane|protein metabolic process|serine-type peptidase activity|proteolysis|serine-type endopeptidase activity|endopeptidase activity - - - - chr16:1271651-1275257 0.250908947 0.052958592 2.244227254 0.001046 0.020595261 UP ENSG00000249926 RP11-495K9.6 - - - - - - - chr12:132147141-132149249 0.461835631 0.112179586 2.041569315 0.00113774 0.021851542 UP ENSG00000230387 RP4-737E23.2 - - - - - - - chr20:23168765-23170944 19.51866974 7.123442784 1.454208158 0.001153462 0.022038718 UP ENSG00000152128 TMEM163 transmembrane protein 163 [Source:HGNC Symbol;Acc:HGNC:25380] - - - - - - chr2:135213330-135476570 0.373634729 0.131426259 1.507375006 0.001186297 0.022466536 UP ENSG00000214700 C12orf71 chromosome 12 open reading frame 71 [Source:HGNC Symbol;Acc:HGNC:34452] - - - - - - chr12:27233991-27235447 0.595069045 0.244249518 1.284701359 0.001215382 0.02287637 UP ENSG00000108759 KRT32 "keratin 32, type I [Source:HGNC Symbol;Acc:HGNC:6449]" GO:0005576|GO:0005623|GO:0005198|GO:0043226|GO:0032502|GO:0032991|GO:0005622|GO:0043229|GO:0048856|GO:0043234|GO:0043227|GO:0009888|GO:0070062|GO:0005882|GO:0031982|GO:0060429|GO:0005856|GO:0008544|GO:0045111 extracellular region|cell|structural molecule activity|organelle|developmental process|macromolecular complex|intracellular|intracellular organelle|anatomical structure development|protein complex|membrane-bounded organelle|tissue development|extracellular exosome|intermediate filament|vesicle|epithelium development|cytoskeleton|epidermis development|intermediate filament cytoskeleton - - - - chr17:39616063-39623681 2.016860804 0.780662524 1.369340599 0.001241546 0.023189597 UP ENSG00000250850 RP11-297B17.3 - - - - - - - chr9:37002694-37008037 0.120978611 0 Inf 0.00124843 0.023301324 UP ENSG00000104237 RP1 retinitis pigmentosa 1 (autosomal dominant) [Source:HGNC Symbol;Acc:HGNC:10263] GO:0023052|GO:0005623|GO:0050896|GO:0043226|GO:0009987|GO:0032502|GO:0032991|GO:0005488|GO:0005622|GO:0043229|GO:0048856|GO:0016043|GO:0050794|GO:0051716|GO:0009605|GO:0005929|GO:0042995|GO:0048646|GO:0005515|GO:0051606|GO:0009653|GO:0043234|GO:0009628|GO:0003407|GO:0042592|GO:0008092|GO:0048468|GO:0001750|GO:0030030|GO:0009888|GO:0072372|GO:0048731|GO:0032403|GO:0005737|GO:0007423|GO:0009582|GO:0048869|GO:0007275|GO:0022607|GO:0007017|GO:0005930|GO:0009314|GO:0005875|GO:0060041|GO:0005874|GO:0009887|GO:0048729|GO:0045494|GO:0050877|GO:0048513|GO:0048871|GO:0006996|GO:0001917|GO:0007165|GO:0007154|GO:0008017|GO:0007010|GO:0060042|GO:0031513|GO:0030154|GO:0009416|GO:0042384|GO:0001894|GO:0048666|GO:0007399|GO:0000902|GO:0032990|GO:0007602|GO:0048858|GO:0015631|GO:0001654|GO:0035556|GO:0060219|GO:0030031|GO:0007600|GO:0044782|GO:0070925|GO:0000226|GO:0009583|GO:0035082|GO:0005856|GO:0022008|GO:0035845|GO:0001578|GO:0001895|GO:0050953|GO:0015630|GO:0042461|GO:0071482|GO:0007603|GO:0030182|GO:0032391|GO:0060271|GO:0048592|GO:0009584|GO:0043010|GO:0042462|GO:0048593|GO:0048699|GO:0007601|GO:0001754|GO:0046549|GO:0046548 "signaling|cell|response to stimulus|organelle|cellular process|developmental process|macromolecular complex|binding|intracellular|intracellular organelle|anatomical structure development|cellular component organization|regulation of cellular process|cellular response to stimulus|response to external stimulus|cilium|cell projection|anatomical structure formation involved in morphogenesis|protein binding|detection of stimulus|anatomical structure morphogenesis|protein complex|response to abiotic stimulus|neural retina development|homeostatic process|cytoskeletal protein binding|cell development|photoreceptor outer segment|cell projection organization|tissue development|primary cilium|system development|protein complex binding|cytoplasm|sensory organ development|detection of abiotic stimulus|cellular developmental process|multicellular organism development|cellular component assembly|microtubule-based process|axoneme|response to radiation|microtubule associated complex|retina development in camera-type eye|microtubule|organ morphogenesis|tissue morphogenesis|photoreceptor cell maintenance|neurological system process|animal organ development|multicellular organismal homeostasis|organelle organization|photoreceptor inner segment|signal transduction|cell communication|microtubule binding|cytoskeleton organization|retina morphogenesis in camera-type eye|nonmotile primary cilium|cell differentiation|response to light stimulus|cilium assembly|tissue homeostasis|neuron development|nervous system development|cell morphogenesis|cell part morphogenesis|phototransduction|cell projection morphogenesis|tubulin binding|eye development|intracellular signal transduction|camera-type eye photoreceptor cell differentiation|cell projection assembly|sensory perception|cilium organization|organelle assembly|microtubule cytoskeleton organization|detection of light stimulus|axoneme assembly|cytoskeleton|neurogenesis|photoreceptor cell outer segment organization|microtubule bundle formation|retina homeostasis|sensory perception of light stimulus|microtubule cytoskeleton|photoreceptor cell development|cellular response to light stimulus|phototransduction, visible light|neuron differentiation|photoreceptor connecting cilium|cilium morphogenesis|eye morphogenesis|detection of visible light|camera-type eye development|eye photoreceptor cell development|camera-type eye morphogenesis|generation of neurons|visual perception|eye photoreceptor cell differentiation|retinal cone cell development|retinal rod cell development" - - - - chr8:55528627-55543394 0.2790589 0.115618019 1.271203408 0.001254082 0.023344114 UP ENSG00000254163 CTC-340I23.2 - - - - - - - chr5:156131069-156166823 0.211295959 0 Inf 0.001308269 0.024070103 UP ENSG00000260655 CTA-250D10.23 - - - - - - - chr22:42318027-42319104 2.492592162 0.967814655 1.364844159 0.001324922 0.024186862 UP ENSG00000176075 LINC00302 long intergenic non-protein coding RNA 302 [Source:HGNC Symbol;Acc:HGNC:31825] - - - - - - chr1:152627953-152629280 0.480975477 0.082672519 2.540483585 0.001378855 0.024942099 UP ENSG00000132854 KANK4 KN motif and ankyrin repeat domains 4 [Source:HGNC Symbol;Acc:HGNC:27263] - - - - - - chr1:62702651-62785085 1.357194601 0.570423601 1.250522017 0.001420918 0.025492996 UP ENSG00000159307 SCUBE1 "signal peptide, CUB domain, EGF-like 1 [Source:HGNC Symbol;Acc:HGNC:13441]" GO:0005576|GO:0016020|GO:0005623|GO:0050896|GO:0009987|GO:0032502|GO:0005488|GO:0019898|GO:0048856|GO:0016043|GO:0043167|GO:0006950|GO:0071944|GO:0005886|GO:0005515|GO:0009986|GO:0005615|GO:0006952|GO:0009888|GO:0048731|GO:0019897|GO:0048869|GO:0007275|GO:0022607|GO:0046983|GO:0009611|GO:0009791|GO:0042802|GO:0007507|GO:0043169|GO:0050878|GO:0048513|GO:0009897|GO:0042060|GO:0030154|GO:0007512|GO:0060429|GO:0006461|GO:0072358|GO:0065003|GO:0046872|GO:0007599|GO:0072359|GO:0007596|GO:0006954|GO:0046982|GO:0051259|GO:0003158|GO:0005509|GO:0030855|GO:0051260|GO:0045446 extracellular region|membrane|cell|response to stimulus|cellular process|developmental process|binding|extrinsic component of membrane|anatomical structure development|cellular component organization|ion binding|response to stress|cell periphery|plasma membrane|protein binding|cell surface|extracellular space|defense response|tissue development|system development|extrinsic component of plasma membrane|cellular developmental process|multicellular organism development|cellular component assembly|protein dimerization activity|response to wounding|post-embryonic development|identical protein binding|heart development|cation binding|regulation of body fluid levels|animal organ development|external side of plasma membrane|wound healing|cell differentiation|adult heart development|epithelium development|protein complex assembly|cardiovascular system development|macromolecular complex assembly|metal ion binding|hemostasis|circulatory system development|blood coagulation|inflammatory response|protein heterodimerization activity|protein oligomerization|endothelium development|calcium ion binding|epithelial cell differentiation|protein homooligomerization|endothelial cell differentiation - - - - chr22:43599229-43739394 0.634300485 0.28626109 1.147834859 0.001461567 0.026072853 UP ENSG00000189152 GRAPL GRB2-related adaptor protein-like [Source:HGNC Symbol;Acc:HGNC:37240] GO:0005488|GO:0005515 binding|protein binding - - - - chr17:19030782-19062489 0.2885865 0.104351709 1.467549578 0.001500139 0.026613807 UP ENSG00000011590 ZBTB32 zinc finger and BTB domain containing 32 [Source:HGNC Symbol;Acc:HGNC:16763] GO:0005623|GO:0050896|GO:0002376|GO:0043226|GO:0009987|GO:0000988|GO:0008152|GO:0032502|GO:0005488|GO:0008283|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0002520|GO:0050794|GO:0009058|GO:0051716|GO:0043167|GO:0006950|GO:0007155|GO:0000989|GO:0006807|GO:0097159|GO:0005515|GO:0045321|GO:0019222|GO:0009892|GO:0048523|GO:0043227|GO:0071704|GO:0016337|GO:0001816|GO:0033554|GO:0046649|GO:0048731|GO:1901360|GO:0044249|GO:0006139|GO:0007275|GO:0043231|GO:0034641|GO:0001775|GO:0070489|GO:0006725|GO:0009890|GO:0031324|GO:0006281|GO:0003676|GO:0043169|GO:0070661|GO:0046483|GO:0031323|GO:0003712|GO:0048513|GO:0098609|GO:0001817|GO:0003714|GO:0030097|GO:0046651|GO:0010468|GO:0005634|GO:0006974|GO:0000228|GO:0010629|GO:0005654|GO:0009059|GO:0042110|GO:0003677|GO:0005694|GO:0051252|GO:0031981|GO:0046872|GO:0006259|GO:0007159|GO:0034645|GO:0010467|GO:0032943|GO:0016070|GO:0032774|GO:0006351|GO:0042098|GO:0045892|GO:0046914|GO:0006355|GO:1902679|GO:2001141|GO:0070486|GO:0006357|GO:1903506|GO:1903507|GO:0008270|GO:0071593|GO:0006366|GO:0000122 "cell|response to stimulus|immune system process|organelle|cellular process|transcription factor activity, protein binding|metabolic process|developmental process|binding|cell proliferation|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|immune system development|regulation of cellular process|biosynthetic process|cellular response to stimulus|ion binding|response to stress|cell adhesion|transcription factor activity, transcription factor binding|nitrogen compound metabolic process|organic cyclic compound binding|protein binding|leukocyte activation|regulation of metabolic process|negative regulation of metabolic process|negative regulation of cellular process|membrane-bounded organelle|organic substance metabolic process|single organismal cell-cell adhesion|cytokine production|cellular response to stress|lymphocyte activation|system development|organic cyclic compound metabolic process|cellular biosynthetic process|nucleobase-containing compound metabolic process|multicellular organism development|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|cell activation|T cell aggregation|cellular aromatic compound metabolic process|negative regulation of biosynthetic process|negative regulation of cellular metabolic process|DNA repair|nucleic acid binding|cation binding|leukocyte proliferation|heterocycle metabolic process|regulation of cellular metabolic process|transcription cofactor activity|animal organ development|cell-cell adhesion|regulation of cytokine production|transcription corepressor activity|hemopoiesis|lymphocyte proliferation|regulation of gene expression|nucleus|cellular response to DNA damage stimulus|nuclear chromosome|negative regulation of gene expression|nucleoplasm|macromolecule biosynthetic process|T cell activation|DNA binding|chromosome|regulation of RNA metabolic process|nuclear lumen|metal ion binding|DNA metabolic process|leukocyte cell-cell adhesion|cellular macromolecule biosynthetic process|gene expression|mononuclear cell proliferation|RNA metabolic process|RNA biosynthetic process|transcription, DNA-templated|T cell proliferation|negative regulation of transcription, DNA-templated|transition metal ion binding|regulation of transcription, DNA-templated|negative regulation of RNA biosynthetic process|regulation of RNA biosynthetic process|leukocyte aggregation|regulation of transcription from RNA polymerase II promoter|regulation of nucleic acid-templated transcription|negative regulation of nucleic acid-templated transcription|zinc ion binding|lymphocyte aggregation|transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter" - - - - chr19:36195429-36207940 0.594344247 0.246411593 1.270228657 0.001572707 0.027651849 UP ENSG00000156234 CXCL13 chemokine (C-X-C motif) ligand 13 [Source:HGNC Symbol;Acc:HGNC:10639] - - K10032 C-X-C motif chemokine 13[-] hsa04060|hsa04062 Cytokine-cytokine receptor interaction - Homo sapiens (human)|Chemokine signaling pathway - Homo sapiens (human) chr4:78432907-78532988 4.135217885 0.355688649 3.539276509 0.001577992 0.027652882 UP ENSG00000171360 KRT38 "keratin 38, type I [Source:HGNC Symbol;Acc:HGNC:6456]" GO:0005576|GO:0005623|GO:0005198|GO:0043226|GO:0032991|GO:0005488|GO:0005622|GO:0043229|GO:0005515|GO:0043234|GO:0043227|GO:0070062|GO:0005882|GO:0031982|GO:0005856|GO:0045111 extracellular region|cell|structural molecule activity|organelle|macromolecular complex|binding|intracellular|intracellular organelle|protein binding|protein complex|membrane-bounded organelle|extracellular exosome|intermediate filament|vesicle|cytoskeleton|intermediate filament cytoskeleton - - - - chr17:39592698-39597173 0.531581249 0.104308473 2.349433867 0.001637267 0.028429132 UP ENSG00000232629 HLA-DQB2 "major histocompatibility complex, class II, DQ beta 2 [Source:HGNC Symbol;Acc:HGNC:4945]" GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0002376|GO:0004871|GO:0043226|GO:0009987|GO:0032991|GO:0005488|GO:0012505|GO:0002684|GO:0038023|GO:0031224|GO:0031090|GO:0006955|GO:0005622|GO:0043229|GO:0050794|GO:0051716|GO:0005789|GO:0006950|GO:0007155|GO:0071944|GO:0005886|GO:0005515|GO:0042175|GO:0045321|GO:0043234|GO:0019882|GO:0043227|GO:0002682|GO:0004872|GO:0002253|GO:0045087|GO:0010033|GO:0006952|GO:0016337|GO:0004888|GO:0050776|GO:0031301|GO:0046649|GO:0005774|GO:0005737|GO:0030155|GO:0030176|GO:0050867|GO:0030658|GO:0043231|GO:0005794|GO:0001775|GO:0070489|GO:0030133|GO:0010008|GO:0002504|GO:0016021|GO:0050865|GO:0005768|GO:0002696|GO:0012506|GO:0098588|GO:0019884|GO:0005783|GO:0050778|GO:0045785|GO:0031982|GO:0007165|GO:0098609|GO:0031295|GO:0030666|GO:0031227|GO:0007154|GO:0030659|GO:0005802|GO:0022409|GO:0051249|GO:0000139|GO:0034341|GO:0034097|GO:0002495|GO:0030669|GO:0042110|GO:0031410|GO:0030134|GO:0012507|GO:0034109|GO:0007159|GO:0030665|GO:0005773|GO:0051251|GO:0071556|GO:0007166|GO:0022407|GO:0002764|GO:0016023|GO:0031988|GO:0032395|GO:0071310|GO:0042613|GO:0002768|GO:0034112|GO:0030135|GO:0071346|GO:0019221|GO:0000323|GO:0071345|GO:0050870|GO:0050863|GO:0019886|GO:0005765|GO:0070486|GO:0032588|GO:0050851|GO:0030139|GO:0060333|GO:0050852|GO:0005764|GO:0071593|GO:0045334|GO:0030136 "signaling|membrane|cell|response to stimulus|immune system process|signal transducer activity|organelle|cellular process|macromolecular complex|binding|endomembrane system|positive regulation of immune system process|signaling receptor activity|intrinsic component of membrane|organelle membrane|immune response|intracellular|intracellular organelle|regulation of cellular process|cellular response to stimulus|endoplasmic reticulum membrane|response to stress|cell adhesion|cell periphery|plasma membrane|protein binding|nuclear outer membrane-endoplasmic reticulum membrane network|leukocyte activation|protein complex|antigen processing and presentation|membrane-bounded organelle|regulation of immune system process|receptor activity|activation of immune response|innate immune response|response to organic substance|defense response|single organismal cell-cell adhesion|transmembrane signaling receptor activity|regulation of immune response|integral component of organelle membrane|lymphocyte activation|vacuolar membrane|cytoplasm|regulation of cell adhesion|integral component of endoplasmic reticulum membrane|positive regulation of cell activation|transport vesicle membrane|intracellular membrane-bounded organelle|Golgi apparatus|cell activation|T cell aggregation|transport vesicle|endosome membrane|antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|integral component of membrane|regulation of cell activation|endosome|positive regulation of leukocyte activation|vesicle membrane|bounding membrane of organelle|antigen processing and presentation of exogenous antigen|endoplasmic reticulum|positive regulation of immune response|positive regulation of cell adhesion|vesicle|signal transduction|cell-cell adhesion|T cell costimulation|endocytic vesicle membrane|intrinsic component of endoplasmic reticulum membrane|cell communication|cytoplasmic vesicle membrane|trans-Golgi network|positive regulation of cell-cell adhesion|regulation of lymphocyte activation|Golgi membrane|response to interferon-gamma|response to cytokine|antigen processing and presentation of peptide antigen via MHC class II|clathrin-coated endocytic vesicle membrane|T cell activation|cytoplasmic vesicle|ER to Golgi transport vesicle|ER to Golgi transport vesicle membrane|homotypic cell-cell adhesion|leukocyte cell-cell adhesion|clathrin-coated vesicle membrane|vacuole|positive regulation of lymphocyte activation|integral component of lumenal side of endoplasmic reticulum membrane|cell surface receptor signaling pathway|regulation of cell-cell adhesion|immune response-regulating signaling pathway|cytoplasmic, membrane-bounded vesicle|membrane-bounded vesicle|MHC class II receptor activity|cellular response to organic substance|MHC class II protein complex|immune response-regulating cell surface receptor signaling pathway|positive regulation of homotypic cell-cell adhesion|coated vesicle|cellular response to interferon-gamma|cytokine-mediated signaling pathway|lytic vacuole|cellular response to cytokine stimulus|positive regulation of T cell activation|regulation of T cell activation|antigen processing and presentation of exogenous peptide antigen via MHC class II|lysosomal membrane|leukocyte aggregation|trans-Golgi network membrane|antigen receptor-mediated signaling pathway|endocytic vesicle|interferon-gamma-mediated signaling pathway|T cell receptor signaling pathway|lysosome|lymphocyte aggregation|clathrin-coated endocytic vesicle|clathrin-coated vesicle" - - - - chr6:32723875-32731311 0.848286335 0.301014958 1.494716145 0.001663962 0.028749565 UP ENSG00000186150 UBL4B ubiquitin like 4B [Source:HGNC Symbol;Acc:HGNC:32309] GO:0005623|GO:0009987|GO:0005488|GO:0005622|GO:0051050|GO:0016043|GO:0050794|GO:0051641|GO:0005515|GO:0051222|GO:0051128|GO:0045184|GO:0005737|GO:0008104|GO:0060341|GO:0032880|GO:0006810|GO:0032388|GO:0051649|GO:0051130|GO:0006996|GO:0090316|GO:0032386|GO:0034613|GO:1903955|GO:0051223|GO:0070201|GO:0006626|GO:0015031|GO:0046907|GO:0072594|GO:0007005|GO:0010638|GO:0033043|GO:0006886|GO:0033157|GO:0033365|GO:1903214|GO:0016482|GO:0010822|GO:0006605|GO:0006839|GO:0010821|GO:0070585|GO:1903533 cell|cellular process|binding|intracellular|positive regulation of transport|cellular component organization|regulation of cellular process|cellular localization|protein binding|positive regulation of protein transport|regulation of cellular component organization|establishment of protein localization|cytoplasm|protein localization|regulation of cellular localization|regulation of protein localization|transport|positive regulation of intracellular transport|establishment of localization in cell|positive regulation of cellular component organization|organelle organization|positive regulation of intracellular protein transport|regulation of intracellular transport|cellular protein localization|positive regulation of protein targeting to mitochondrion|regulation of protein transport|regulation of establishment of protein localization|protein targeting to mitochondrion|protein transport|intracellular transport|establishment of protein localization to organelle|mitochondrion organization|positive regulation of organelle organization|regulation of organelle organization|intracellular protein transport|regulation of intracellular protein transport|protein localization to organelle|regulation of protein targeting to mitochondrion|cytosolic transport|positive regulation of mitochondrion organization|protein targeting|mitochondrial transport|regulation of mitochondrion organization|protein localization to mitochondrion|regulation of protein targeting - - - - chr1:110655062-110656569 2.003175275 0.87480162 1.195260864 0.001718019 0.029330173 UP ENSG00000165966 PDZRN4 PDZ domain containing ring finger 4 [Source:HGNC Symbol;Acc:HGNC:30552] GO:0003824|GO:0009987|GO:0008152|GO:0005488|GO:0044237|GO:0043167|GO:0005515|GO:0016740|GO:0071704|GO:0019787|GO:0019538|GO:0043169|GO:0044267|GO:0004842|GO:0043412|GO:0046872|GO:0006464|GO:0046914|GO:0061630|GO:0008270|GO:0032446|GO:0016567 catalytic activity|cellular process|metabolic process|binding|cellular metabolic process|ion binding|protein binding|transferase activity|organic substance metabolic process|ubiquitin-like protein transferase activity|protein metabolic process|cation binding|cellular protein metabolic process|ubiquitin-protein transferase activity|macromolecule modification|metal ion binding|cellular protein modification process|transition metal ion binding|ubiquitin protein ligase activity|zinc ion binding|protein modification by small protein conjugation|protein ubiquitination - - - - chr12:41582250-41968384 0.538308504 0.16175352 1.73463611 0.001840545 0.031031991 UP ENSG00000113924 HGD "homogentisate 1,2-dioxygenase [Source:HGNC Symbol;Acc:HGNC:4892]" GO:0005576|GO:0005623|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0009056|GO:0005622|GO:0044237|GO:0043167|GO:0006807|GO:0043227|GO:0016491|GO:0071704|GO:0006520|GO:1901360|GO:0016701|GO:0005737|GO:0055114|GO:0006082|GO:0070062|GO:0034641|GO:0006725|GO:0051213|GO:0043169|GO:0044281|GO:0031982|GO:0005829|GO:0016702|GO:0019439|GO:0046872|GO:1901605|GO:0009063|GO:0009072|GO:0009074|GO:0006558|GO:0006570|GO:0004411|GO:0046395|GO:0019752|GO:0006559|GO:0006572 "extracellular region|cell|catalytic activity|organelle|cellular process|metabolic process|binding|catabolic process|intracellular|cellular metabolic process|ion binding|nitrogen compound metabolic process|membrane-bounded organelle|oxidoreductase activity|organic substance metabolic process|cellular amino acid metabolic process|organic cyclic compound metabolic process|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen|cytoplasm|oxidation-reduction process|organic acid metabolic process|extracellular exosome|cellular nitrogen compound metabolic process|cellular aromatic compound metabolic process|dioxygenase activity|cation binding|small molecule metabolic process|vesicle|cytosol|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|aromatic compound catabolic process|metal ion binding|alpha-amino acid metabolic process|cellular amino acid catabolic process|aromatic amino acid family metabolic process|aromatic amino acid family catabolic process|L-phenylalanine metabolic process|tyrosine metabolic process|homogentisate 1,2-dioxygenase activity|carboxylic acid catabolic process|carboxylic acid metabolic process|L-phenylalanine catabolic process|tyrosine catabolic process" K00451 "homogentisate 1,2-dioxygenase[1.13.11.5]" hsa01100|hsa00350 Metabolic pathways - Homo sapiens (human)|Tyrosine metabolism - Homo sapiens (human) chr3:120347020-120401418 4.859352657 2.067882702 1.232609784 0.001856492 0.031198979 UP ENSG00000224875 AC083949.1 - - - - - - - chr2:42370378-42397441 0.07146003 0 Inf 0.001898342 0.031695929 UP ENSG00000122543 OCM oncomodulin [Source:HGNC Symbol;Acc:HGNC:8105] GO:0005488|GO:0043167|GO:0043169|GO:0046872|GO:0005509 binding|ion binding|cation binding|metal ion binding|calcium ion binding - - - - chr7:5919458-5925993 0.539264674 0.241375054 1.15971695 0.0019051 0.031767663 UP ENSG00000138378 STAT4 signal transducer and activator of transcription 4 [Source:HGNC Symbol;Acc:HGNC:11365] GO:0001071|GO:0023052|GO:0005623|GO:0050896|GO:0004871|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0009893|GO:0008283|GO:0005622|GO:0043229|GO:0044237|GO:0050794|GO:0009058|GO:0051716|GO:0003700|GO:0006807|GO:0097159|GO:0005515|GO:0019222|GO:0043227|GO:0071704|GO:0010033|GO:1901360|GO:0005737|GO:0044249|GO:0006139|GO:0043231|GO:0034641|GO:0006725|GO:0031325|GO:0019538|GO:0003676|GO:0046483|GO:0031323|GO:0007165|GO:0007154|GO:0010628|GO:0031328|GO:0010468|GO:0005634|GO:0044267|GO:0034097|GO:0005654|GO:0010557|GO:0009059|GO:0003677|GO:0043412|GO:0051252|GO:0031981|GO:0035556|GO:0034645|GO:0010467|GO:0006796|GO:0007166|GO:0016070|GO:0071310|GO:0032774|GO:0006464|GO:0006351|GO:0045893|GO:0016310|GO:0006355|GO:0000975|GO:0019221|GO:0043565|GO:0071345|GO:0003690|GO:2001141|GO:0006357|GO:1903506|GO:0044212|GO:0006366|GO:0007259|GO:0006468|GO:0045944|GO:0001012|GO:0000976|GO:0000977 "nucleic acid binding transcription factor activity|signaling|cell|response to stimulus|signal transducer activity|organelle|cellular process|metabolic process|binding|positive regulation of metabolic process|cell proliferation|intracellular|intracellular organelle|cellular metabolic process|regulation of cellular process|biosynthetic process|cellular response to stimulus|transcription factor activity, sequence-specific DNA binding|nitrogen compound metabolic process|organic cyclic compound binding|protein binding|regulation of metabolic process|membrane-bounded organelle|organic substance metabolic process|response to organic substance|organic cyclic compound metabolic process|cytoplasm|cellular biosynthetic process|nucleobase-containing compound metabolic process|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|cellular aromatic compound metabolic process|positive regulation of cellular metabolic process|protein metabolic process|nucleic acid binding|heterocycle metabolic process|regulation of cellular metabolic process|signal transduction|cell communication|positive regulation of gene expression|positive regulation of cellular biosynthetic process|regulation of gene expression|nucleus|cellular protein metabolic process|response to cytokine|nucleoplasm|positive regulation of macromolecule biosynthetic process|macromolecule biosynthetic process|DNA binding|macromolecule modification|regulation of RNA metabolic process|nuclear lumen|intracellular signal transduction|cellular macromolecule biosynthetic process|gene expression|phosphate-containing compound metabolic process|cell surface receptor signaling pathway|RNA metabolic process|cellular response to organic substance|RNA biosynthetic process|cellular protein modification process|transcription, DNA-templated|positive regulation of transcription, DNA-templated|phosphorylation|regulation of transcription, DNA-templated|regulatory region DNA binding|cytokine-mediated signaling pathway|sequence-specific DNA binding|cellular response to cytokine stimulus|double-stranded DNA binding|regulation of RNA biosynthetic process|regulation of transcription from RNA polymerase II promoter|regulation of nucleic acid-templated transcription|transcription regulatory region DNA binding|transcription from RNA polymerase II promoter|JAK-STAT cascade|protein phosphorylation|positive regulation of transcription from RNA polymerase II promoter|RNA polymerase II regulatory region DNA binding|transcription regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding" K11222 signal transducer and activator of transcription 4[-] hsa04630|hsa05161|hsa05321 Jak-STAT signaling pathway - Homo sapiens (human)|Hepatitis B - Homo sapiens (human)|Inflammatory bowel disease (IBD) - Homo sapiens (human) chr2:191894302-192016322 1.303895525 0.629833256 1.049786437 0.001912046 0.031862909 UP ENSG00000266378 RP11-214O1.3 - - - - - - - chr17:14230652-14232791 0.103115392 0.016767999 2.620477273 0.001949843 0.032260775 UP ENSG00000169495 HTRA4 HtrA serine peptidase 4 [Source:HGNC Symbol;Acc:HGNC:26909] GO:0023052|GO:0005576|GO:0050896|GO:0003824|GO:0040007|GO:0009987|GO:0008152|GO:0005488|GO:0023057|GO:0040008|GO:0016043|GO:0050794|GO:0051716|GO:0016787|GO:0005515|GO:0048523|GO:0016049|GO:0071704|GO:0010033|GO:0051128|GO:0008233|GO:0090288|GO:0009968|GO:0071559|GO:0009966|GO:0017171|GO:0019538|GO:0001558|GO:0007165|GO:0019838|GO:0010646|GO:0007154|GO:0070848|GO:0005520|GO:0008236|GO:0006508|GO:0071560|GO:0007166|GO:0071310|GO:0071363|GO:0004252|GO:0017015|GO:0004175|GO:0007179|GO:0030512|GO:0007167|GO:0007178 signaling|extracellular region|response to stimulus|catalytic activity|growth|cellular process|metabolic process|binding|negative regulation of signaling|regulation of growth|cellular component organization|regulation of cellular process|cellular response to stimulus|hydrolase activity|protein binding|negative regulation of cellular process|cell growth|organic substance metabolic process|response to organic substance|regulation of cellular component organization|peptidase activity|negative regulation of cellular response to growth factor stimulus|negative regulation of signal transduction|response to transforming growth factor beta|regulation of signal transduction|serine hydrolase activity|protein metabolic process|regulation of cell growth|signal transduction|growth factor binding|regulation of cell communication|cell communication|response to growth factor|insulin-like growth factor binding|serine-type peptidase activity|proteolysis|cellular response to transforming growth factor beta stimulus|cell surface receptor signaling pathway|cellular response to organic substance|cellular response to growth factor stimulus|serine-type endopeptidase activity|regulation of transforming growth factor beta receptor signaling pathway|endopeptidase activity|transforming growth factor beta receptor signaling pathway|negative regulation of transforming growth factor beta receptor signaling pathway|enzyme linked receptor protein signaling pathway|transmembrane receptor protein serine/threonine kinase signaling pathway - - - - chr8:38831683-38846181 0.6508477 0.285697995 1.187829079 0.001959092 0.032374796 UP ENSG00000178031 ADAMTSL1 ADAMTS like 1 [Source:HGNC Symbol;Acc:HGNC:14632] GO:0005576|GO:0031012|GO:0005623|GO:0003824|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0012505|GO:0005622|GO:0043229|GO:0044237|GO:0009058|GO:0043167|GO:0016787|GO:0005515|GO:0043227|GO:0005578|GO:0071704|GO:0008233|GO:0005737|GO:0044249|GO:0043231|GO:0019538|GO:0043169|GO:0005783|GO:0005975|GO:0006486|GO:0006493|GO:0070085|GO:0044267|GO:0005788|GO:0009059|GO:0009100|GO:0043412|GO:0046872|GO:0006508|GO:1901137|GO:0034645|GO:0006464|GO:0043413|GO:0036065|GO:0009101|GO:0008237|GO:0046914|GO:0004175|GO:0036066|GO:0004222|GO:0043687|GO:0008270 extracellular region|extracellular matrix|cell|catalytic activity|organelle|cellular process|metabolic process|binding|endomembrane system|intracellular|intracellular organelle|cellular metabolic process|biosynthetic process|ion binding|hydrolase activity|protein binding|membrane-bounded organelle|proteinaceous extracellular matrix|organic substance metabolic process|peptidase activity|cytoplasm|cellular biosynthetic process|intracellular membrane-bounded organelle|protein metabolic process|cation binding|endoplasmic reticulum|carbohydrate metabolic process|protein glycosylation|protein O-linked glycosylation|glycosylation|cellular protein metabolic process|endoplasmic reticulum lumen|macromolecule biosynthetic process|glycoprotein metabolic process|macromolecule modification|metal ion binding|proteolysis|carbohydrate derivative biosynthetic process|cellular macromolecule biosynthetic process|cellular protein modification process|macromolecule glycosylation|fucosylation|glycoprotein biosynthetic process|metallopeptidase activity|transition metal ion binding|endopeptidase activity|protein O-linked fucosylation|metalloendopeptidase activity|post-translational protein modification|zinc ion binding - - - - chr9:18473892-18910948 2.393648292 1.087030742 1.138818446 0.002004653 0.032796046 UP ENSG00000166917 RP13-49I15.5 MIR202 host gene [Source:HGNC Symbol;Acc:HGNC:49402] - - - - - - chr10:135059982-135061395 0.537926115 0.230390498 1.223326812 0.002028396 0.033034068 UP ENSG00000183837 PNMA3 paraneoplastic Ma antigen 3 [Source:HGNC Symbol;Acc:HGNC:18742] GO:0005623|GO:0043226|GO:0009987|GO:0005488|GO:0005622|GO:0043229|GO:0050794|GO:0043167|GO:0097159|GO:0043227|GO:0043231|GO:0010942|GO:0008219|GO:0003676|GO:0043169|GO:0010941|GO:0043068|GO:0005634|GO:0043067|GO:0031981|GO:0046872|GO:0012501|GO:0005730|GO:0046914|GO:0043065|GO:0006915|GO:0042981|GO:0008270 cell|organelle|cellular process|binding|intracellular|intracellular organelle|regulation of cellular process|ion binding|organic cyclic compound binding|membrane-bounded organelle|intracellular membrane-bounded organelle|positive regulation of cell death|cell death|nucleic acid binding|cation binding|regulation of cell death|positive regulation of programmed cell death|nucleus|regulation of programmed cell death|nuclear lumen|metal ion binding|programmed cell death|nucleolus|transition metal ion binding|positive regulation of apoptotic process|apoptotic process|regulation of apoptotic process|zinc ion binding - - - - chrX:152224766-152228827 0.23791236 0.118683878 1.003306247 0.002045608 0.033219363 UP ENSG00000197705 KLHL14 kelch like family member 14 [Source:HGNC Symbol;Acc:HGNC:29266] - - - - - - chr18:30252634-30353025 9.259729569 3.70087608 1.323103231 0.00206689 0.033428962 UP ENSG00000185669 SNAI3 snail family zinc finger 3 [Source:HGNC Symbol;Acc:HGNC:18411] GO:0001071|GO:0005623|GO:0043226|GO:0009987|GO:0008152|GO:0032991|GO:0005488|GO:0005622|GO:0043229|GO:0044237|GO:0050794|GO:0009058|GO:0043167|GO:0003700|GO:0006807|GO:0097159|GO:0019222|GO:0009892|GO:0048523|GO:0043234|GO:0043227|GO:0071704|GO:0005667|GO:0000981|GO:1901360|GO:0044249|GO:0006139|GO:0043231|GO:0034641|GO:0006725|GO:0009890|GO:0031324|GO:0003676|GO:0043169|GO:0046483|GO:0031323|GO:0010468|GO:0005634|GO:0010629|GO:0009059|GO:0003677|GO:0051252|GO:0000982|GO:0046872|GO:0034645|GO:0010467|GO:0001227|GO:0016070|GO:0032774|GO:0006351|GO:0045892|GO:0046914|GO:0006355|GO:0000975|GO:1902679|GO:0043565|GO:0003690|GO:2001141|GO:0006357|GO:1903506|GO:1903507|GO:0044212|GO:0005507|GO:0006366|GO:0000122|GO:0001012|GO:0001159|GO:0000976|GO:0000977|GO:0000987|GO:0000978 "nucleic acid binding transcription factor activity|cell|organelle|cellular process|metabolic process|macromolecular complex|binding|intracellular|intracellular organelle|cellular metabolic process|regulation of cellular process|biosynthetic process|ion binding|transcription factor activity, sequence-specific DNA binding|nitrogen compound metabolic process|organic cyclic compound binding|regulation of metabolic process|negative regulation of metabolic process|negative regulation of cellular process|protein complex|membrane-bounded organelle|organic substance metabolic process|transcription factor complex|RNA polymerase II transcription factor activity, sequence-specific DNA binding|organic cyclic compound metabolic process|cellular biosynthetic process|nucleobase-containing compound metabolic process|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|cellular aromatic compound metabolic process|negative regulation of biosynthetic process|negative regulation of cellular metabolic process|nucleic acid binding|cation binding|heterocycle metabolic process|regulation of cellular metabolic process|regulation of gene expression|nucleus|negative regulation of gene expression|macromolecule biosynthetic process|DNA binding|regulation of RNA metabolic process|transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding|metal ion binding|cellular macromolecule biosynthetic process|gene expression|transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding|RNA metabolic process|RNA biosynthetic process|transcription, DNA-templated|negative regulation of transcription, DNA-templated|transition metal ion binding|regulation of transcription, DNA-templated|regulatory region DNA binding|negative regulation of RNA biosynthetic process|sequence-specific DNA binding|double-stranded DNA binding|regulation of RNA biosynthetic process|regulation of transcription from RNA polymerase II promoter|regulation of nucleic acid-templated transcription|negative regulation of nucleic acid-templated transcription|transcription regulatory region DNA binding|copper ion binding|transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|RNA polymerase II regulatory region DNA binding|core promoter proximal region DNA binding|transcription regulatory region sequence-specific DNA binding|RNA polymerase II regulatory region sequence-specific DNA binding|core promoter proximal region sequence-specific DNA binding|RNA polymerase II core promoter proximal region sequence-specific DNA binding" - - - - chr16:88744090-88752901 1.26339348 0.626612706 1.011658102 0.002127086 0.034061081 UP ENSG00000250328 CTC-210G5.1 uncharacterized LOC153163 [Source:EntrezGene;Acc:153163] - - - - - - chr5:121772192-121814782 0.593916901 0.251527248 1.239546391 0.002135806 0.034137187 UP ENSG00000236268 RP11-170N11.1 long intergenic non-protein coding RNA 1361 [Source:HGNC Symbol;Acc:HGNC:50595] - - - - - - chr1:83439565-83451891 0.111660898 0.035153432 1.667386613 0.00218712 0.034656929 UP ENSG00000187912 CLEC17A C-type lectin domain family 17 member A [Source:HGNC Symbol;Acc:HGNC:34520] GO:0016020|GO:0005623|GO:0005488|GO:0031224|GO:0030246|GO:0043167|GO:0009986|GO:0036094|GO:0048029|GO:0016021|GO:0043169|GO:0042806|GO:0046872|GO:0005537 membrane|cell|binding|intrinsic component of membrane|carbohydrate binding|ion binding|cell surface|small molecule binding|monosaccharide binding|integral component of membrane|cation binding|fucose binding|metal ion binding|mannose binding - - - - chr19:14693896-14721969 0.288598485 0.060240071 2.260268361 0.002191245 0.034700992 UP ENSG00000258673 RP4-773N10.6 long intergenic non-protein coding RNA 1397 [Source:HGNC Symbol;Acc:HGNC:50677] - - - - - - chr1:110625310-110652341 2.031678498 0.771059831 1.397757404 0.002341299 0.036451111 UP ENSG00000236938 AC003092.2 - - - - - - - chr7:93701071-93706469 4.384490114 0.739602896 2.567586298 0.002437547 0.037469998 UP ENSG00000101082 SLA2 Src-like-adaptor 2 [Source:HGNC Symbol;Acc:HGNC:17329] GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0002376|GO:0043226|GO:0009987|GO:0008152|GO:0005488|GO:0012505|GO:0060090|GO:0023057|GO:0002683|GO:0002684|GO:0031090|GO:0006955|GO:0005622|GO:0043229|GO:0044237|GO:0050794|GO:0009058|GO:0051716|GO:0007155|GO:0006807|GO:0071944|GO:0005886|GO:0005515|GO:0045321|GO:0019222|GO:0009892|GO:0048523|GO:0043227|GO:0002682|GO:0071704|GO:0002253|GO:0016337|GO:0050776|GO:0047485|GO:0046649|GO:1901360|GO:0005737|GO:0009968|GO:0044249|GO:0030674|GO:0006139|GO:0002250|GO:0009966|GO:0043231|GO:0034641|GO:0001775|GO:0070489|GO:0010008|GO:0009967|GO:0002695|GO:0006725|GO:0050865|GO:0009890|GO:0035591|GO:0005768|GO:0098588|GO:0031324|GO:0050778|GO:0046483|GO:0031323|GO:0031982|GO:0007165|GO:0098609|GO:0010646|GO:0007154|GO:0002443|GO:0042113|GO:0010468|GO:0051249|GO:1902532|GO:0005770|GO:0010629|GO:0009059|GO:0042110|GO:0002460|GO:0031410|GO:0051252|GO:0005070|GO:0035556|GO:0007159|GO:0034645|GO:0030522|GO:0010467|GO:0007166|GO:0016070|GO:0002764|GO:0051250|GO:0016023|GO:0031988|GO:0032774|GO:0006351|GO:0002768|GO:0045892|GO:0050864|GO:0050849|GO:0006355|GO:0019932|GO:1902679|GO:0050848|GO:0019724|GO:0050869|GO:2001141|GO:0070486|GO:0050851|GO:0006357|GO:1903506|GO:1903507|GO:0071593|GO:0006366|GO:0000122|GO:0019722 "signaling|membrane|cell|response to stimulus|immune system process|organelle|cellular process|metabolic process|binding|endomembrane system|binding, bridging|negative regulation of signaling|negative regulation of immune system process|positive regulation of immune system process|organelle membrane|immune response|intracellular|intracellular organelle|cellular metabolic process|regulation of cellular process|biosynthetic process|cellular response to stimulus|cell adhesion|nitrogen compound metabolic process|cell periphery|plasma membrane|protein binding|leukocyte activation|regulation of metabolic process|negative regulation of metabolic process|negative regulation of cellular process|membrane-bounded organelle|regulation of immune system process|organic substance metabolic process|activation of immune response|single organismal cell-cell adhesion|regulation of immune response|protein N-terminus binding|lymphocyte activation|organic cyclic compound metabolic process|cytoplasm|negative regulation of signal transduction|cellular biosynthetic process|protein binding, bridging|nucleobase-containing compound metabolic process|adaptive immune response|regulation of signal transduction|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|cell activation|T cell aggregation|endosome membrane|positive regulation of signal transduction|negative regulation of leukocyte activation|cellular aromatic compound metabolic process|regulation of cell activation|negative regulation of biosynthetic process|signaling adaptor activity|endosome|bounding membrane of organelle|negative regulation of cellular metabolic process|positive regulation of immune response|heterocycle metabolic process|regulation of cellular metabolic process|vesicle|signal transduction|cell-cell adhesion|regulation of cell communication|cell communication|leukocyte mediated immunity|B cell activation|regulation of gene expression|regulation of lymphocyte activation|negative regulation of intracellular signal transduction|late endosome|negative regulation of gene expression|macromolecule biosynthetic process|T cell activation|adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains|cytoplasmic vesicle|regulation of RNA metabolic process|SH3/SH2 adaptor activity|intracellular signal transduction|leukocyte cell-cell adhesion|cellular macromolecule biosynthetic process|intracellular receptor signaling pathway|gene expression|cell surface receptor signaling pathway|RNA metabolic process|immune response-regulating signaling pathway|negative regulation of lymphocyte activation|cytoplasmic, membrane-bounded vesicle|membrane-bounded vesicle|RNA biosynthetic process|transcription, DNA-templated|immune response-regulating cell surface receptor signaling pathway|negative regulation of transcription, DNA-templated|regulation of B cell activation|negative regulation of calcium-mediated signaling|regulation of transcription, DNA-templated|second-messenger-mediated signaling|negative regulation of RNA biosynthetic process|regulation of calcium-mediated signaling|B cell mediated immunity|negative regulation of B cell activation|regulation of RNA biosynthetic process|leukocyte aggregation|antigen receptor-mediated signaling pathway|regulation of transcription from RNA polymerase II promoter|regulation of nucleic acid-templated transcription|negative regulation of nucleic acid-templated transcription|lymphocyte aggregation|transcription from RNA polymerase II promoter|negative regulation of transcription from RNA polymerase II promoter|calcium-mediated signaling" - - - - chr20:35240721-35274619 1.017998757 0.458101728 1.151995891 0.002505186 0.038218899 UP ENSG00000198046 ZNF667 zinc finger protein 667 [Source:HGNC Symbol;Acc:HGNC:28854] GO:0005623|GO:0043226|GO:0009987|GO:0000988|GO:0008152|GO:0005488|GO:0005622|GO:0043229|GO:0044237|GO:0050794|GO:0009058|GO:0043167|GO:0000989|GO:0006807|GO:0097159|GO:0019222|GO:0043227|GO:0071704|GO:1901360|GO:0044249|GO:0006139|GO:0043231|GO:0034641|GO:0006725|GO:0003676|GO:0043169|GO:0046483|GO:0031323|GO:0003712|GO:0010468|GO:0005634|GO:0009059|GO:0003677|GO:0051252|GO:0046872|GO:0034645|GO:0010467|GO:0016070|GO:0032774|GO:0006351|GO:0006355|GO:2001141|GO:0006357|GO:1903506|GO:0006366 "cell|organelle|cellular process|transcription factor activity, protein binding|metabolic process|binding|intracellular|intracellular organelle|cellular metabolic process|regulation of cellular process|biosynthetic process|ion binding|transcription factor activity, transcription factor binding|nitrogen compound metabolic process|organic cyclic compound binding|regulation of metabolic process|membrane-bounded organelle|organic substance metabolic process|organic cyclic compound metabolic process|cellular biosynthetic process|nucleobase-containing compound metabolic process|intracellular membrane-bounded organelle|cellular nitrogen compound metabolic process|cellular aromatic compound metabolic process|nucleic acid binding|cation binding|heterocycle metabolic process|regulation of cellular metabolic process|transcription cofactor activity|regulation of gene expression|nucleus|macromolecule biosynthetic process|DNA binding|regulation of RNA metabolic process|metal ion binding|cellular macromolecule biosynthetic process|gene expression|RNA metabolic process|RNA biosynthetic process|transcription, DNA-templated|regulation of transcription, DNA-templated|regulation of RNA biosynthetic process|regulation of transcription from RNA polymerase II promoter|regulation of nucleic acid-templated transcription|transcription from RNA polymerase II promoter" - - - - chr19:56950694-56989434 0.96581947 0.454038856 1.088937781 0.00258951 0.039089489 UP ENSG00000147655 RSPO2 R-spondin 2 [Source:HGNC Symbol;Acc:HGNC:28583] GO:0023052|GO:0005576|GO:0005623|GO:0050896|GO:0040007|GO:0009987|GO:0032502|GO:0005488|GO:0048589|GO:0048856|GO:0050794|GO:0051716|GO:0043167|GO:0097367|GO:0005515|GO:0009986|GO:0009653|GO:0050793|GO:0005615|GO:0005539|GO:0005102|GO:0009888|GO:0035295|GO:0048731|GO:0030323|GO:0001503|GO:0035239|GO:0048869|GO:0007275|GO:0009966|GO:0009967|GO:0001763|GO:0048598|GO:0009887|GO:0048729|GO:0048513|GO:0030324|GO:0007165|GO:0010646|GO:0007154|GO:0035265|GO:0060438|GO:0008201|GO:0031214|GO:0060425|GO:0060437|GO:0060439|GO:0009790|GO:0030154|GO:0060562|GO:0030177|GO:0061138|GO:0060173|GO:0060429|GO:0001649|GO:2000027|GO:0061448|GO:0007399|GO:0042476|GO:0060534|GO:0001501|GO:0030282|GO:0042489|GO:0048754|GO:0051216|GO:0060541|GO:0060536|GO:0035108|GO:0007166|GO:0030111|GO:0001664|GO:0002009|GO:0060828|GO:0042475|GO:0022008|GO:0060535|GO:0042481|GO:0016055|GO:0035137|GO:0030326|GO:0060441|GO:0090263|GO:0030182|GO:0035136|GO:0048699|GO:0060070|GO:0042487|GO:0071542|GO:0035116|GO:0035115 signaling|extracellular region|cell|response to stimulus|growth|cellular process|developmental process|binding|developmental growth|anatomical structure development|regulation of cellular process|cellular response to stimulus|ion binding|carbohydrate derivative binding|protein binding|cell surface|anatomical structure morphogenesis|regulation of developmental process|extracellular space|glycosaminoglycan binding|receptor binding|tissue development|tube development|system development|respiratory tube development|ossification|tube morphogenesis|cellular developmental process|multicellular organism development|regulation of signal transduction|positive regulation of signal transduction|morphogenesis of a branching structure|embryonic morphogenesis|organ morphogenesis|tissue morphogenesis|animal organ development|lung development|signal transduction|regulation of cell communication|cell communication|organ growth|trachea development|heparin binding|biomineral tissue development|lung morphogenesis|lung growth|trachea morphogenesis|embryo development|cell differentiation|epithelial tube morphogenesis|positive regulation of Wnt signaling pathway|morphogenesis of a branching epithelium|limb development|epithelium development|osteoblast differentiation|regulation of organ morphogenesis|connective tissue development|nervous system development|odontogenesis|trachea cartilage development|skeletal system development|bone mineralization|negative regulation of odontogenesis of dentin-containing tooth|branching morphogenesis of an epithelial tube|cartilage development|respiratory system development|cartilage morphogenesis|limb morphogenesis|cell surface receptor signaling pathway|regulation of Wnt signaling pathway|G-protein coupled receptor binding|morphogenesis of an epithelium|regulation of canonical Wnt signaling pathway|odontogenesis of dentin-containing tooth|neurogenesis|trachea cartilage morphogenesis|regulation of odontogenesis|Wnt signaling pathway|hindlimb morphogenesis|embryonic limb morphogenesis|epithelial tube branching involved in lung morphogenesis|positive regulation of canonical Wnt signaling pathway|neuron differentiation|forelimb morphogenesis|generation of neurons|canonical Wnt signaling pathway|regulation of odontogenesis of dentin-containing tooth|dopaminergic neuron differentiation|embryonic hindlimb morphogenesis|embryonic forelimb morphogenesis - - - - chr8:108911544-109095913 0.112641553 0.022009987 2.35550896 0.002613162 0.039342996 UP ENSG00000160161 CILP2 cartilage intermediate layer protein 2 [Source:HGNC Symbol;Acc:HGNC:24213] GO:0005576|GO:0031012|GO:0043226|GO:0005488|GO:0030246|GO:0005515|GO:0043227|GO:0005578|GO:0070062|GO:0031982 extracellular region|extracellular matrix|organelle|binding|carbohydrate binding|protein binding|membrane-bounded organelle|proteinaceous extracellular matrix|extracellular exosome|vesicle - - - - chr19:19649057-19657468 0.120465637 0.049254014 1.290308451 0.002641009 0.03968124 UP ENSG00000172867 KRT2 "keratin 2, type II [Source:HGNC Symbol;Acc:HGNC:6439]" - - - - - - chr12:53038342-53045948 3.03615642 1.432581945 1.083628454 0.002687926 0.040075007 UP ENSG00000142178 SIK1 salt inducible kinase 1 [Source:HGNC Symbol;Acc:HGNC:11142] - - K19008 serine/threonine-protein kinase SIK1[2.7.11.1] hsa04922 Glucagon signaling pathway - Homo sapiens (human) chr21:44834395-44847008 77.32661219 33.83993237 1.192238323 0.002774235 0.041014505 UP ENSG00000213132 AC022498.1 - - - - - - - chr3:187896331-187898598 0.150308303 0.042162487 1.833892817 0.002868876 0.042009639 UP ENSG00000183098 GPC6 glypican 6 [Source:HGNC Symbol;Acc:HGNC:4454] - - - - - - chr13:93879095-95059655 1.93942164 0.883439917 1.134422561 0.002911049 0.042310195 UP ENSG00000036828 CASR calcium-sensing receptor [Source:HGNC Symbol;Acc:HGNC:1514] GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0003824|GO:0007610|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0009893|GO:0038023|GO:0031224|GO:0048856|GO:0050794|GO:0051716|GO:0071944|GO:0016787|GO:0005886|GO:0005515|GO:0044708|GO:0051606|GO:0009653|GO:0019222|GO:0004872|GO:0071704|GO:0042592|GO:0016788|GO:0004888|GO:0019725|GO:0031226|GO:0007635|GO:0009593|GO:0001503|GO:0043085|GO:0050790|GO:0006810|GO:0016021|GO:0005887|GO:0010035|GO:0007165|GO:0007154|GO:0010628|GO:0043269|GO:0010468|GO:0042578|GO:0016298|GO:0006811|GO:0005513|GO:0007186|GO:0010038|GO:0051345|GO:0010467|GO:0048878|GO:0004930|GO:0055082|GO:0006873|GO:0051592|GO:0032781|GO:0050801|GO:0006812|GO:0043462|GO:0004620|GO:0008081|GO:0051924|GO:0004629|GO:0030003|GO:0030001|GO:0055065|GO:0004435|GO:0006875|GO:0006816|GO:0055074|GO:0006874|GO:0070509 "signaling|membrane|cell|response to stimulus|signal transducer activity|catalytic activity|behavior|cellular process|metabolic process|developmental process|binding|positive regulation of metabolic process|signaling receptor activity|intrinsic component of membrane|anatomical structure development|regulation of cellular process|cellular response to stimulus|cell periphery|hydrolase activity|plasma membrane|protein binding|single-organism behavior|detection of stimulus|anatomical structure morphogenesis|regulation of metabolic process|receptor activity|organic substance metabolic process|homeostatic process|hydrolase activity, acting on ester bonds|transmembrane signaling receptor activity|cellular homeostasis|intrinsic component of plasma membrane|chemosensory behavior|detection of chemical stimulus|ossification|positive regulation of catalytic activity|regulation of catalytic activity|transport|integral component of membrane|integral component of plasma membrane|response to inorganic substance|signal transduction|cell communication|positive regulation of gene expression|regulation of ion transport|regulation of gene expression|phosphoric ester hydrolase activity|lipase activity|ion transport|detection of calcium ion|G-protein coupled receptor signaling pathway|response to metal ion|positive regulation of hydrolase activity|gene expression|chemical homeostasis|G-protein coupled receptor activity|cellular chemical homeostasis|cellular ion homeostasis|response to calcium ion|positive regulation of ATPase activity|ion homeostasis|cation transport|regulation of ATPase activity|phospholipase activity|phosphoric diester hydrolase activity|regulation of calcium ion transport|phospholipase C activity|cellular cation homeostasis|metal ion transport|metal ion homeostasis|phosphatidylinositol phospholipase C activity|cellular metal ion homeostasis|calcium ion transport|calcium ion homeostasis|cellular calcium ion homeostasis|calcium ion import" - - - - chr3:121902530-122005342 0.035435882 0.002473597 3.840528817 0.002965042 0.042853651 UP ENSG00000163958 ZDHHC19 "zinc finger, DHHC-type containing 19 [Source:HGNC Symbol;Acc:HGNC:20713]" GO:0016020|GO:0005623|GO:0003824|GO:0043226|GO:0008152|GO:0005488|GO:0012505|GO:0031224|GO:0005622|GO:0043229|GO:0043167|GO:0016740|GO:0043227|GO:0005737|GO:0016746|GO:0043231|GO:0016021|GO:0043169|GO:0005783|GO:0046872|GO:0016747|GO:0046914|GO:0016409|GO:0008270|GO:0019706 "membrane|cell|catalytic activity|organelle|metabolic process|binding|endomembrane system|intrinsic component of membrane|intracellular|intracellular organelle|ion binding|transferase activity|membrane-bounded organelle|cytoplasm|transferase activity, transferring acyl groups|intracellular membrane-bounded organelle|integral component of membrane|cation binding|endoplasmic reticulum|metal ion binding|transferase activity, transferring acyl groups other than amino-acyl groups|transition metal ion binding|palmitoyltransferase activity|zinc ion binding|protein-cysteine S-palmitoyltransferase activity" - - - - chr3:195924320-195938266 0.243636536 0.068126912 1.838433775 0.003017312 0.043319408 UP ENSG00000139330 KERA keratocan [Source:HGNC Symbol;Acc:HGNC:6309] GO:0005576|GO:0031012|GO:0005623|GO:0050896|GO:0043226|GO:0009987|GO:0008152|GO:0032502|GO:0005488|GO:0012505|GO:0009056|GO:0005622|GO:0043229|GO:0048856|GO:0044237|GO:0009405|GO:0009058|GO:0006807|GO:0005515|GO:0043227|GO:0005578|GO:0071704|GO:0048731|GO:0005737|GO:0007423|GO:0044249|GO:0006082|GO:0007275|GO:0061303|GO:0043231|GO:0005794|GO:0006790|GO:0044281|GO:0005975|GO:0050877|GO:0048513|GO:0005796|GO:0009059|GO:0042339|GO:0042340|GO:0001654|GO:1901137|GO:0007600|GO:0005773|GO:0005775|GO:0018146|GO:0043202|GO:0050953|GO:0030203|GO:0006024|GO:0000323|GO:0043010|GO:0007601|GO:0005764|GO:0006027 extracellular region|extracellular matrix|cell|response to stimulus|organelle|cellular process|metabolic process|developmental process|binding|endomembrane system|catabolic process|intracellular|intracellular organelle|anatomical structure development|cellular metabolic process|pathogenesis|biosynthetic process|nitrogen compound metabolic process|protein binding|membrane-bounded organelle|proteinaceous extracellular matrix|organic substance metabolic process|system development|cytoplasm|sensory organ development|cellular biosynthetic process|organic acid metabolic process|multicellular organism development|cornea development in camera-type eye|intracellular membrane-bounded organelle|Golgi apparatus|sulfur compound metabolic process|small molecule metabolic process|carbohydrate metabolic process|neurological system process|animal organ development|Golgi lumen|macromolecule biosynthetic process|keratan sulfate metabolic process|keratan sulfate catabolic process|eye development|carbohydrate derivative biosynthetic process|sensory perception|vacuole|vacuolar lumen|keratan sulfate biosynthetic process|lysosomal lumen|sensory perception of light stimulus|glycosaminoglycan metabolic process|glycosaminoglycan biosynthetic process|lytic vacuole|camera-type eye development|visual perception|lysosome|glycosaminoglycan catabolic process - - - - chr12:91444268-91451760 0.140689804 0.036260285 1.956055626 0.003024659 0.043399397 UP ENSG00000235961 PNMA6C paraneoplastic Ma antigen family member 6A [Source:HGNC Symbol;Acc:HGNC:28248] GO:0005488|GO:0005515 binding|protein binding - - - - chrX:152240819-152243401 0.445907731 0.154376869 1.530288614 0.003070934 0.043941251 UP ENSG00000171209 CSN3 casein kappa [Source:HGNC Symbol;Acc:HGNC:2446] GO:0005576|GO:0032502|GO:0005488|GO:0048856|GO:0005515|GO:0005615|GO:0031647|GO:0048731|GO:0007275|GO:0006810|GO:0050878|GO:0048513|GO:0048732|GO:0007595|GO:0046903|GO:0030879|GO:0050821|GO:0007589 extracellular region|developmental process|binding|anatomical structure development|protein binding|extracellular space|regulation of protein stability|system development|multicellular organism development|transport|regulation of body fluid levels|animal organ development|gland development|lactation|secretion|mammary gland development|protein stabilization|body fluid secretion - - - - chr4:71108305-71117145 0.132886941 0 Inf 0.003085044 0.044094263 UP ENSG00000237531 RP11-309M23.1 - - - - - - - chrX:950956-955100 0.513998544 0.061465314 3.063919871 0.003110491 0.044286317 UP ENSG00000269647 BX842679.1 - - - - - - - chr1:147631967-147632428 4.539117235 2.088434259 1.11999002 0.003233113 0.045604565 UP ENSG00000254548 RP11-429J17.5 - - - - - - - chr8:144800416-144801061 1.293140968 0.458710826 1.495222695 0.003328435 0.046366377 UP ENSG00000205106 CTD-2210P24.4 uncharacterized DKFZp779M0652 [Source:EntrezGene;Acc:374387] - - - - - - chr11:45792983-45793909 0.745466349 0.18886514 1.980786794 0.003344674 0.04651728 UP ENSG00000178732 GP5 glycoprotein V (platelet) [Source:HGNC Symbol;Acc:HGNC:4443] - - K06260 platelet glycoprotein V[-] hsa04611|hsa04640|hsa04512 Platelet activation - Homo sapiens (human)|Hematopoietic cell lineage - Homo sapiens (human)|ECM-receptor interaction - Homo sapiens (human) chr3:194115550-194119995 0.108665566 0.045662899 1.250800472 0.003432595 0.047382666 UP ENSG00000234695 AC002076.10 - - - - - - - chr7:93520225-93522913 0.37374112 0.077183032 2.275683677 0.00357462 0.048846828 UP ENSG00000188389 PDCD1 programmed cell death 1 [Source:HGNC Symbol;Acc:HGNC:8760] - - K06744 programmed cell death protein 1[-] hsa04514|hsa04660 Cell adhesion molecules (CAMs) - Homo sapiens (human)|T cell receptor signaling pathway - Homo sapiens (human) chr2:242792033-242801060 1.459873598 0.592193658 1.301702516 0.003618464 0.049159689 UP ENSG00000168828 OR13J1 olfactory receptor family 13 subfamily J member 1 [Source:HGNC Symbol;Acc:HGNC:15108] GO:0023052|GO:0016020|GO:0005623|GO:0050896|GO:0004871|GO:0009987|GO:0038023|GO:0031224|GO:0050794|GO:0051716|GO:0071944|GO:0005886|GO:0051606|GO:0004872|GO:0004888|GO:0009593|GO:0016021|GO:0050877|GO:0050906|GO:0007165|GO:0007154|GO:0050907|GO:0007186|GO:0004984|GO:0007600|GO:0004930|GO:0050911|GO:0007606|GO:0007608 signaling|membrane|cell|response to stimulus|signal transducer activity|cellular process|signaling receptor activity|intrinsic component of membrane|regulation of cellular process|cellular response to stimulus|cell periphery|plasma membrane|detection of stimulus|receptor activity|transmembrane signaling receptor activity|detection of chemical stimulus|integral component of membrane|neurological system process|detection of stimulus involved in sensory perception|signal transduction|cell communication|detection of chemical stimulus involved in sensory perception|G-protein coupled receptor signaling pathway|olfactory receptor activity|sensory perception|G-protein coupled receptor activity|detection of chemical stimulus involved in sensory perception of smell|sensory perception of chemical stimulus|sensory perception of smell K04257 olfactory receptor[-] hsa04740 Olfactory transduction - Homo sapiens (human) chr9:35869375-35870461 0.128138713 0.020241431 2.662323219 0.003700357 0.049947593 UP ENSG00000262292 RP11-160E2.11 - - - - - - - chr17:19064102-19065587 0.271286033 0.079296925 1.774477943 0.003701613 0.049947593 UP