COVID-19 Models include collections of cellular signalling models and molecular networks depicting mechanism of SARS-CoV2 infection and COVID19 complications. --> Pathways were built in the Pathway Studio environment and based on a database of literature - extracted relationships. All pathways include annotations of entities and relationships between them (sentence with indexed evidence, paper ID, links, and others). --> Signaling pathways constructed manually. --> Network pathways represent sub-clusters of the Pathway Studio network. COVID-19 pathways is a work in progress due to fast evolved research in the field of SARS-CoV2 biology. Pathway Studio database updates bi-weekly with facts from newly published papers. Signalings are curated and updated on regular basis. Links to individual pathways are updated automatically.
Steps to reproduce
Pathways are uploaded in RNEF XML format, Use open source rnef2sbgn.py converter to convert them into SBGN format. Link to rnef2sbgn.py converter https://github.com/golovatenkop/rnef2sbgn