The Journal of Molecular Diagnostics

Dataset 1. Sequencing and z-score normalized data results from reference and CNS samples. (A and B) Reference population coverage with means and standard deviations used to calculate z-scores shown at the top. Amplicon z-scores and followed by gene z-scores (A) and EGFRvIII z-scores (B) used to identify focal gene amplification (z-score > 5, final column in A) and EGFRvIII (z-score > 10, final column in B), respectively (EGFR.d2.7 = EGFRvIII). Dataset 2. Reference values used to calculate amplicon and EGFRvIII z-scores from raw coverage matrix and sample metadata. For complete and actively updated repository that uses this reference data, refer to https://github.com/Michael-L-Miller/CoveRageAnalysis (doi:10.5281/zenodo.1220399).

Dataset of variants used in this study

1343 NSCLC patients. Molecular diagnosis, CAST vs NGS. Description of molecular alterations (alterations associations, identifications of new actionable targets) using NGS.

This is NGS data (VCF files) for targeted sequencing panels (Illumina Inherited Disease Panel and Ion Torrent AmpliSeq Inherited Disease Panel) performed on NIST RMs 8398, 8392 and 8393 (NA12878, GM24149, GM24143, GM24385, GM24631).

Dataset contain raw data relate to article mentioned at title