TRPML1 promotes protein homeostasis in melanoma cells by negatively regulating MAPK and mTORC1 signaling. Kasitinon et al.
In vivo shRNA dropout screen against ion channel- and transporter-encoding genes in 3 different patient-derived melanomas. Datasets include data from a primary screen and a secondary screen. Each row corresponds to a gene name and each column corresponds to the log2-transformed relative abundance of a particular shRNA in a particular sample.