The dataset present here was used in the study "Plasma Tie2 is a tumor vascular biomarker for VEGF inhibitors". The data comprised three subsets as below: circulating biomarker data: CEP 099 longitudianl_working.xls Imaging biomaker from MRI: travastin_imaging_summaryData.xls Patient clinical information: Travastin_clinical_info_final_04_2015 The three datasets can be aligned by the patient IDs (PID). In circulating biomarker data, the sheet "average" contains all the biomarker concentrations that were averaged from two technical replicates. The original technical replicate values can be found in "All raw data" sheet. A brief introduction of imaging biomarker can be found in a seperate file. We believe the clinical information are self-explainary.