Expanding upper limit of bond strength of highly porous yttria-stabilized-zirconia membranes by the dendritic phase zirconium oxycarbides in situ synthesized
Contributors: Fangwei Guo
... Expanding upper limit of bond strength of highly porous yttria-stabilized-zirconia membranes by the dendritic phase zirconium oxycarbides in situ synthesized
Contributors: Chang Sun
... Codes and Data to Replicate Results in the Paper "Multinational Production with Non-neutral Technologies" This paper develops a quantitative model of multinational production (MP) with non-neutral technologies incorporating two stylized facts observed in a global firm-level data: first, larger firms on average use more capital-intensive technologies; second, among firms producing in the same industry and country, those from more capital-abundant home countries use more capital-intensive technologies. I quantify the model using both firm-level and aggregate moments for 37 countries. I found that the reduction in MP costs accounts for 56% of the average decline in labor shares from 1996 to 2011, and the model also replicates a negative relationship between the change in a country's labor share and the change in the foreign affiliates' output share as observed in the data.
Data for: Paleoenvironmental change on coastal SE Zagros during the last two millennia using paleoreconstruction of Khuran Estuary
Contributors: Mohammad Ali Hamzeh, Sedigheh Farahi Ghasr-Aboonasr
... Data are about physical properties of the sediment core, distribution of foraminifers, ages and GIS-based shapefiles.
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Contributors: Ahinoam Pollack
... This dataset includes data relevant to a research project investigating the cause of surface expression in a section of the Midway Sunset Oil Field. The data includes earth models of the Midway Sunset Oil Field (well data, core data, surfaces, property models), a presentation on this topic, and surface expression data. The surface expression excel sheet provides the presence/absence of surface expressions in relation to other parameters (such as concentration of plugged wells, seal thickness, etc.).
Contributors: Yucheng Sheng
... SAEM and FOCEI Algorithms in nlmixr
Contributors: Gaetan Montero, Cécile Tannier, Isabelle Thomas
... Contributors: Gaëtan Montero, Cécile Tannier, Isabelle Thomas Date:2019-16-10 Description: This data set can be used to reproduce the analyses made by the authors in their paper “Morphological delineation of cities based on scaling properties of urban patterns: a comparison of three methods”. It contains 12 shapefiles that represent theoretical urban patterns and 4 shapefiles that can be used to delineate the morphological agglomeration of Brussels (Belgium). It also contains a R script to calculate the carrying capacity of a logistic percolation function. Description of each file 2_Figure_1: theoretical street network for testing the Natural Cities method 3_Figure_2: theoretical street network for the comparison of two variants of the Natural Cities method 4_Figure_3: theoretical street network to evaluate the effects of the spatial extent of the study area on the delineation of Natural Cities 5_Figure_5a: theoretical pattern for testing MorphoLim (building footprints) – dense urban core 6_Figure_5b: theoretical pattern for testing MorphoLim (building footprints) – less dense urban core 7_Figure_6: theoretical pattern (building footprints) to evaluate the effects of the geographic extent of the study area on the delineation with MorphoLim 8_Percolation_C_Calculation: R code to calculate the carrying capacity of a logistic function (Hierarchical Percolation) 9_Figure_7: theoretical street network for testing Hierarchical Percolation 10_Figure_8: theoretical polycentric street network for testing Hierarchical Percolation 11_Figure_9ac: theoretical urban pattern crossed by a large non built area (road intersections) 12_Figure_9b: theoretical urban pattern crossed by a large non built area (building footprints) 13_Figure_10ac: theoretical pattern where a built ribbon links two urban centres (roads intersections ) 14_Figure_10b: theoretical pattern where a built ribbon links two urban centres (building footprints) 15_Belgium_buildings: cadastral data of buildings (2D) for Belgium (© 2009 Administration Générale de la Documentation Patrimoniale) 16_Brabant_buildings: cadastral data of buildings (2D) for the province of Brabant (© 2009 Administration Générale de la Documentation Patrimoniale) 17_Belgium_roads: road network data come from the platform Geofabrik of OpenStreetMap (http://download.geofabrik.de, accessed 08/21/2018) for Belgium 18_Brabant_roads: Road network data come from the platform Geofabrik of OpenStreetMap (http://download.geofabrik.de, accessed 08/21/2018) for the province of Brabant.
Contributors: Ashot Margaryan, Josefin Stiller, Bent Petersen, Remi-Andre Olsen, Love Dalén, Tomàs Marquès-Bonet, Guojie Zhang, M. Thomas P. Gilbert, Carles Lalueza-Fox
... As the only endemic Neotropical parrot to have recently lived in the northern hemisphere, the Carolina parakeet (Conuropsis carolinensis) was an iconic North American bird. The last surviving specimen died in the Cincinnati Zoo in 1918 (Elphick et al., 2010). The cause of its extinction remains contentious: besides excessive mortality associated to habitat destruction and active hunting, their survival could have been negatively affected by its range having become increasingly patchy (Burgio et al., 2017), or by the exposure to poultry pathogens (Snyder, 2004; Snyder and Russel, 2002). In addition, the Carolina parakeet showed a predilection for cockleburs, an herbaceous plant that contains a powerful toxin, carboxyatractyloside, or CAT (Stuart et al., 1981), which did not seem to affect them but made the birds notoriously toxic to most predators (Snyder, 2004). To explore the demographic history of this bird we generated the complete genomic sequence of a preserved specimen held in a private collection in Spain, as well as of a close extant relative, Aratinga solstitialis. We identified two non-synonymous genetic changes in two highly conserved proteins known to interact with CAT that could underlie a specific dietary adaptation to this toxin. Our genomic analyses did not reveal evidence of a dramatic past demographic decline in the Carolina parakeet; also, its genome did not exhibit the long runs of homozygosity that are signals of recent inbreeding and are typically found in endangered species. As such, our results suggest its extinction was an abrupt process, and thus likely solely attributable to human causes.
Contributors: Nicole Sanford
... - Presentation code and stimuli for the Working Memory Task and the Thought Generation Task. - Predictor weights derived from fMRI-CPCA (single-experiment WM analysis and multi-experiment WM-TGT analysis). - SPSS syntax for running repeated measures ANOVAs for each task, and averaging across load or delay conditions for the Working Memory Task. - Neuroimaging HDR/IMG files for visualizing components for both analyses.
Anti-leukemic properties of aplysinopsin derivative EE-84 alone and in combination with BH3 mimetic A-1210477 (2)
Contributors: Su A Kim
... Aplysinopsins are a class of marine indole alkaloids that exhibit a wide range of biological activities such as prevention of neoplastic growth on an array of different cancer cell lines. Although both the indole and N-benzyl moieties of aplysinopsins are known to possess anti-proliferative activity against cancer cells, their mechanism of action remains unclear. Through in vitro and in vivo proliferation and viability screening of newly synthesized aplysinopsin analogs on myelogenous leukemia cell lines and zebrafish toxicity tests as well as analysis of differential toxicity in non-cancerous RPMI 1788 cells, we identified EE-84 as a promising novel drug candidate against myeloid leukemia. This indole derivative demonstrated drug-likeness in agreement with Lipinski’s rule of five and was responsible for cell cycle dysregulation in K562 cells in line with its cytostatic effect. EE-84-treated K562 cells likewise underwent morphological changes suggesting mitochondrial dysfunction. Finally, we demonstrated the synergistic cytotoxic effect of EE-84 with a BH3 mimetic, the Mcl-1 inhibitor, A-1210477, against K562 cells, highlighting the inhibition of anti-apoptotic Bcl-2 proteins as a promising therapeutic approach against myeloid leukemia in combination with EE-84.
Contributors: Giovanni Caudullo, Erik Welk, Jesús San-Miguel-Ayanz
... The data are organized as a set of ESRI shapefiles (*.shp, *.shx, *.dbf, *.prj files) mapping the distribution ranges of the main European tree and shrub species. For each species and in some cases subspecies, one or more shapefiles have been created containing: a) polygon features (name suffix “plg”), which define continuous areas of occupancy of the species range and b) point features (name suffix “pnt”), which identify more fragmented and isolated populations. For species with reported synanthropic occurrences outside the natural range, an additional point and/or polygon shapefile has also been created (suffix “syn”). Polygon borders delimiting species ranges are generalized across the mainland and sea boundaries. This offers the possibility to mask sea areas or to clip and extract the terrestrial range parts using GIS data layers of the users' choice. An additional version of polygon ranges are clipped with a coastline (name suffix “clip”), which have been derived from Natural Earth dataset "Admin 0 - Countries" 1:50M version 4.1.0 (https://www.naturalearthdata.com). Finally, an accompanying text document is included with the data, which provides more details on methodology and a list of all mapped species with related file names, taxonomical delimitation of the mapped species and references used to compile the respective chorological dataset.