Contributors: Elena Zudilova-Seinstra
... In the selection task, participants had to select the region of interest (a specified vessel segment) as explained in the "Experiment_description.pdf" file. They were asked to manipulate (i.e., translate, rotate and scale) a 3D box widget, initially positioned such that the region of interest covered all vessel structures displayed on the screen. Three 3D model files ("level1.vtk", "level2.vtk" and "level.3 vtk") were used to define three complexity levels of the selection task: Level 1 (simple) — one vessel; Level 2 (average) — two closely located vessels; Level 3 (complex) — three vessels, where two vessels are located close to each other. This project was funded by the University of Amsterdam and NWO.
Contributors: Hossein Dabiriyan Tehrani, sara yamini
... This meta-analysis aimed to address the association between personality traits and conflict handling styles. ProQuest, PsycINFO, Scopus, and Web of Science and also Microsoft Academic, Science.gov, Science open were searched for all published and non-published studies through 17 October 2018. A literature search located 20 eligible studies, and 5337 total participants. The primary hypotheses of this meta-analysis were framed based on the literature as follows: Hypothesis 1: Neuroticism, agreeableness, and extroversion will be positively related to avoiding style and openness to experience, and conscientiousness will be negatively related to avoiding style. Hypothesis 2: Neuroticism, agreeableness, extroversion, openness to experience, and conscientiousness will be positively related to compromising style. Hypothesis 3: Neuroticism, extroversion, openness to experience, and conscientiousness will be positively related to dominating style and agreeableness will be negatively related to dominating style. Hypothesis 4: Neuroticism, agreeableness, extroversion, openness to experience, and conscientiousness will be positively related to obliging style. Hypothesis 5: Agreeableness, extroversion, openness to experience, and conscientiousness will be positively related to integrating style and neuroticism will be negatively related to integrating style. The secondary hypothesis of this meta-analysis seeks to explain the variation of above mentioned hypothesis according to study setting and personality measures. The results of this review show that neuroticism and agreeableness are positively related to avoiding style. The positive associations are observed between agreeableness, extroversion, openness to experience, and conscientiousness with compromising style. There exist positive and negative relations between extroversion and agreeableness with dominating style, respectively. A positive link is identified between agreeableness and obliging style. Finally, agreeableness, extroversion, openness to experience, and conscientiousness are positively correlated with integrating style and neuroticism is negatively related to integrating style. The findings of moderator analysis indicate that there is a different pattern between work and academic settings concerning the relationship between agreeableness with compromising. Similarly, the results of the academic setting yielded the different populations as the work setting when it comes to the link between neuroticism and compromising style. To identify the robustness of findings and probable small study effect, we employed the trim and fill method (Duval & Tweedie, 2000) , file drawer analysis (Rosenthal, 1979) , Begg's rank test (Begg & Mazumdar, 1994) and Egger's linear regression test (Egger, Smith, Schneider, & Minder, 1997). the results of publication bias show that small-study effects are negligible.
Contributors: Alon Poleg-Polsky
... Simulation of neuronal processing of noise-corrupted inputs NEURON simulation (http://neuron.yale.edu/neuron)
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Contributors: Katelyn Newton, Danielle Sebbens
... The aim of this project was to implement an effective educational initiative using standardized guidelines to increase provider knowledge of patients who qualify for palliative care referral, while subsequently impacting referral rates. Educational sessions were developed outlining referral recommendations from the AAP, National Hospice and Palliative Care Organization (NHPCO), and those included in the institutional policy. Presurveys and postsurveys validated by two clinical experts in the field were administered to participants at the time of the intervention. Referral rates for the organization were also collected for two months prior to the intervention, and two months following the intervention.
Oxidative stress induced by the tetrahydrobenzimidazole TMQ0153 modulates crosstalk between apoptosis, autophagy and necroptosis in chronic myeloid leukemia (Part 3 - Figure 4 (b), Figure 5, 6, 7, Supplementary 1-5)
Contributors: Sungmi Song
... Aims: We demonstrate the capacity of the cytotoxic synthetic tetrahydrobenzimidazole (TMQ) hydroquinone (HQ) derivative TMQ0153 to induce reactive oxygen species (ROS) and mediate differential cell death modalities in chronic myeloid leukemia (CML). Results: Results showed that concentrations of TMQ0153 30 µM lead to ROS-mediated necrostatin-sensitive necroptosis. Moreover, TMQ0153 allowed us to elucidate the interplay of ROS-mediated cell death and cell stress/survival mechanisms as this compound triggers protective autophagy in response to metabolic stress in CML cells. Importantly, the modulation of cell stress prior to TMQ0153-induced cell death enhances the exposure of “find-me”/“eat-me” signals considered as hallmarks of immunogenic cell death (ICD), altogether providing a pro-oxidant therapeutic strategy against CML. Innovation: We suggest here a pro-oxidant anti-CML therapy leading to differential cell death modalities in both imatinib-sensitive and -resistant CML cell types. Moreover, we elucidated the interplay between apoptosis, autophagy and controlled necrosis induced by TMQ0153 leading to disruption of mitochondrial homeostasis. Conclusion: Our findings indicate that TMQ0153-induced ROS act as a rheostat determining the onset of apoptotic- or autophagy-related controlled necrotic cell death in CML.
The relationship between regular sinusoidal waves in the tissue at lung-related acupuncture points and the respiration pacesetter mechanism
Contributors: Fletcher Kovich
... This data compliments a paper entitled: The relationship between regular sinusoidal waves in the tissue at lung-related acupuncture points and the respiration pacesetter mechanism. The paper fully describes and analyses the data. At the time of writing, the paper is still in production. Please see the links at the end of this dataset, which will be updated once the paper is published.
Data for: Substantially enhanced varistor properties and dielectric response in (Zn2+, Sn4+) co-doped CaCu3Ti4O12 ceramics
Contributors: Prasit Thongbai
... Raw data for all figures in this paper.
Supporting information for "Parameterising the seasonal-diurnal wind climate of Rome: Fiumicino and Ciampino"
Contributors: Nicholas Cook
... This dataset contains information supporting the above titled paper in Meteorological Applications. The data includes the processed joint PDFs of wind speed and direction from 45 years of observations at half-hour intervals for Fiumicino and Ciampino airports. These data have been analysed by month and time of day to reveal the seasonal-diurnal variation of wind vector, and parameterised by fitting to the OEN model of Harris & Cook (https://doi.org/10.1016/j.jweia.2014.05.005). The joint PDFs are revealed to be a mixture of distinct seven diurnal and three non-diurnal wind-producing mechanisms including calms, local-scale and continental-scale land and sea breezes, transient along-shore jets, down-slope winds and a component attributed to the atmospheric tide. Values of the OEN parameters for each component are provided for the first fit, second fit, Fourier-smoothed and fuzzy OEN model. Charts are provided which compare the second-fit and smoothed model parameters over the seasonal and diurnal cycles. R scripts are provided to reproduce the figures in the paper and the additional charts, and to demonstrate accessing the data for further examination and analysis.
Contributors: Laura Newsome
... Data associated with manuscript 'Manganese and cobalt redox cycling in laterites; biogeochemical and bioprocessing implications'
Contributors: Christine Hartzell
... Matlab codes required to evaluate the feasibility of electrostatic lofting at Bennu, as described in JGR submission, using Zimmerman JGR 2016 charging model. Also, Matlab codes required to propagate trajectories of lofted particles about Bennu.