Contributors: Benjamin Adam, Julie Tucker, Graham Tewksbury
... Gleeble iso-T true stress-strain data at 1000C-1200C in 50C steps for 0.01/s - 1/s; EBSD IPF and BC of geometric centers of sectioned samples; ThermoCalc 2015 calculated property diagrams for stable phases and data tables with compositional changes vs. T for all phases
Data for: Estimating the Yucca schidigera Extract Effective Level on European Seabass Juveniles (Dicentrarchus labrax) Survival, Haematological, Immunological Responses and Water Quality
Contributors: Walied Fayed, Eglal Omar, Abdallah Mansour, Basem Elkhayat, Abdelaziz Nour, Ghada Sallam, riad khalil
... One-way ANOVA; actual photos of the experimental laboratory aquaria
Indented polymer microparticles with shape variety reminiscent of poikilocytosis for intratumoral drug delivery after transarterial chemo-embolization
Contributors: Levinus Koole, Abderazak Benzina, Aigerim Karina, Marion Guillonneau, Samal Tazhibayeva, Haiyan Fan
... This study was conducted to explore the utility of porous embolic microspheres in transarterial embolisation (TACE) with drug-eluting embolic particles. New indented particles porous particles were found, and these show properties which are attractive for further exploration regarding widening of the clinical scope of the TACE technique .
Data for: Ammonia Sensitive SLC4A11 Mitochondrial Uncoupling Reduces Glutamine Induced Oxidative Stress
Contributors: Joseph Bonanno, Rajalekshmy Shyam, Shimin Li, Moonjung Choi, Diego Ogando
... Unedited western blots
Contributors: Yunkyoung Lee
... Lithium salts are commonly used to treat bipolar disease. Despite the frequent prescription of long-term lithium therapy, awareness of obesity, the most serious side-effect, and the mechanisms by which lithium influences lipid metabolism are largely unknown. In the present study, we gained valuable insights into the mechanisms underlying the lipogenic action of lithium by examining its effects on lipid accumulation in both cells and the zebrafish system. We have presented evidence for the first time that lithium induces lipid accumulation through stimulation of intracellular ROS generation via a GSK-3β-independent pathway. Our findings may facilitate the development of novel therapeutic targets to ameliorate side effects of lithium therapy in psychotic patients.
Contributors: Stephan Harrison
... Files to support "Rock Slope Failure in the British Mountains" by David Jarman and Stephan Harrison
Contributors: Ines Diaz-Laviada, Belen Sanchez, Alicia Bort, Pedro Mateos, Nieves Rodríguez-Henche
... Data used to generate figures of the paper “Combination of the natural product capsaicin and docetaxel synergistically kills human prostate cancer cells through the metabolic regulator AMP-activated kinase” Sánchez BG, Bort A, Mateos-Gómez PA, Rodríguez-Henche N, Díaz-Laviada I. Cancer Cell Int. 2019 Mar 8;19:54. doi: 10.1186/s12935-019-0769-2. eCollection 2019. In this study we demonstrate that the spicy ingredient of peepers, capsaicin, sensitizes prostate cancer cell to docetaxel. The metabolic regulator AMPK plays a pivotal role.
Overexpression of AMP-activated kinase sensitizes Sorafenib-resistant Hepatocellular cancer cells and decreases stem cell markers
Contributors: Ines Diaz-Laviada
... Data used to generate figures of the paper by Bort A, Sánchez BG, Mateos-Gómez PA, Vara-Ciruelos D, Rodríguez-Henche N, Díaz-Laviada I. “Targeting AMP-activated kinase impacts hepatocellular cancer stem cells induced by long-term treatment with sorafenib” Mol Oncol. 2019 May;13(5):1311-1331. doi: 10.1002/1878-0261.12488. In this study we demonstrate that the AMP-activated kinase AMPK reverse the Cancer Stem cell features of Hepatocellular CSC.
Virtual outcrop geology comes of age: the application of consumer-grade virtual reality hardware and software to digital outcrop data analysis
Contributors: Thomas Seers, Ali Sheharyar
... In this work, the need for discipline specific analysis tools is addressed by harnessing a consumer grade virtual reality system (HTC Vive) and freeform 3D visual arts software package (Google Tilt Brush) to interactively interpret and analyze sedimentary and structural architecture (bedding contacts, faults, fractures) from digital outcrop models. Having generated these interpretations, users utilize a script library developed in the MATLABTM language to extract geologically useful data (e.g. orientation, length, intensity) from interactively generated 3D mesh patches output by Tilt Brush. Note that the submission contains the MATLAB code library, test data and presentation (.ppt) with videoed examples of Tilt Brush data input and interpretation.