Contributors: Xunhao ding

Date: 2019-10-13

... Data for the testing and micro-crack analysis

Contributors: Melody Esmaeili, Shelby Blythe, Kai Zhang, John Tobias, Jing Yang, Peter Klein

Date: 2019-10-13

... The hypothesis being tested is that loss of competence to respond to inductive signals is mediated by loss of chromatin accessibility. This dataset describes analysis of an Assay for Transposase-Accessible Chromatin followed by sequencing (ATAC-Seq) approach to evaluate genome-wide changes in chromatin accessibility in Xenopus laevis. ATAC-seq identifies ~70,000 accessible regions at early and late gastrula stage; normalized read counts from 3 biological replicates at early (stage 10) and late (stage 12) gastrula stage are presented here. Genome wide distribution of accessible peaks, list of promoters with changes in accessibility between stage 10 and stage 12, comparison with previously published p300 ChIP-seq data to identify putative cis-regulatory modules (pCRMs), comparison of promoter accessibility and gene expression, identification of transcription factor binding motifs associated with pCRMs, and functional gene annotation analyses are presented. Promoters for dorsal genes (Sia and Xnr3) that have lost competence to respond to Wnt signaling are not accessible at the early gastrula stage but competence can be maintained by inhibiting HDACs and increasing histone acetylation at these promoters. Promoters for regulators of mesoderm and neural crest induction maintain accessibility throughout gastrulation despite the loss of competence to respond to their respective inductive signals, suggesting context-dependent regulation of competence. However, 279 promoters lose accessibility at stage 12 and are associated with transcription factors that regulate early development. Accessibility at ≥ 1800 promoter-distal pCRMs is also reduced by the end the gastrula stage, and these pCRMs are frequently near promoters for transcription factors that regulate early development, including homeobox genes. Motif analysis (HOMER) shows marked enrichment for binding sites for pluripotency factors of the Sox, Oct, and KLF transcription factor families, as well as for Fox, Grainyhead-like, and Zic transcription factors.

Contributors: Syed Adnan, David Garrity

Date: 2019-10-13

... The data comprises of time-stamped temperature values in degrees Celsius recorded during fire-suppression exercises conducted at various UK and US fire-training facilities. The first day of the visit was split into two burn sessions as follows: • The first being a demonstration of gas cooling performed in a “lay-flat” chamber. • The second being a re-qualification exercise performed in the multi-compartment chamber. Day 1 - Session 1: Lay-flat chamber Two TMRDs (#5 & #6) were worn in the torch clips on the breathing apparatus (BA) harnesses by the instructors during their demonstration of the “gas cooling” technique for controlling a fire. The fire was lit in the right hand corner of the chamber and as the demonstrations progresses with the fire being allowed to repeatedly develop and then “gas cooling” being deployed the fire progressed to include the fuel in the left hand corner of the chamber. The data logged temperatures show the cycles and the effect of the “gas cooling” technique. Day 1 – Session 2: Multi-compartment chamber Three TMRDs (#5, #7 and #8) were worn in the same position as before by the instructors during the re-qualification exercise (Figure 3). Two other TMRDs were attached to a stand at 1.3m high (#6) and 1.7m high (#9) and the stand was placed in the corner of the burn chamber for the duration of the exercise. The second day was again split into two burn sessions utilising the “Industrial B” building with the firefighting team using standard operating procedures to extinguish the fires. 1.1 Day 2 - Session 1: Top-floor industrial unit B Session 1 was conducted on the upper floor of the building which has a high ceiling where 2 double loadings of fuel were used. Three TMRD units were deployed, one on the helmet and one at chest height on the team fighting the fire and the third on the observer at shoulder height. In this session, 3 TMRDs were used with #B mounted on the helmet of one of the firefighters tackling the burn, #D mounted on the chest of the other firefighter and #C was on the shoulder of the observer. 1.2 Day 2 - Session 2: Lower-floor industrial unit B Session 2 was conducted on the lower floor of the building which has a standard height ceiling where 1 double and 1 single loading of fuel were used. In this session, a total of three TMRD units were deployed, one on the helmet and one at shoulder height on the team fighting the fire and the third on the observer at shoulder height In this session, one double and one single fuel load were utilised and the fire allowed to develop before a firefighting team entered the building and dealt with the fire using their standard operation procedures. The team consisted of two firefighters to tackle the fire and a third to observe and report progress over a radio link where 3 TMRDs were used with #B mounted on the helmet of one of the firefighters tackling the burn, #D mounted on the shoulder of the other firefighter and #C was on the shoulder of the observer.

Contributors: S. Raghavan, Rui Zhang

Date: 2019-10-13

... We provide the instances used in the paper “A Branch-and-Cut Approach for the Weighted Target Set Selection Problem on Social Networks”, by S. Raghavan and Rui Zhang, published in the INFORMS Journal on Optimization (https://doi.org/10.1287/ijoo.2019.0012) . This repository contains the 260 instances used in the paper. All the instances used in the paper are provided in a compressed archive. The accompanying data is contained in the following file: --InstancesWTSS.zip Description: There are two main folders: One called "Real-World Graphs" contains 180 instances based on real-world graphs. The other one called "Simulated Graphs" contains all instances based on simulated graphs. Within the Simulated Graphs folder, 50 200-node instances are in the "200 Nodes" folder and 30 large instances are in the "Large" folder. For each text file, there are m+2 lines. The first m lines are the edges in the graphs. Nodes are labeled from 0 to n where n is the largest number in the first m lines. The (m+1)th line contains the weight (b) for each node. The (m+2)th line contains the threshold value (g) for each node. The excel file “WTSS_Results.xlsx” reports, for each instance, the upper and lower bounds obtained in the paper.

Contributors: Hiroshi Yokouchi

Date: 2019-10-13

... Data Sharing. Raw data of major mutations detected by BioReT System. Synonymous and potential germline mutations were omitted. Numbers in a pop down menu indicate registration number of each patient. Please see the detail in the Results Section of the manuscript. (Manuscipt: Detection of somatic TP53 mutation in surgically resected small-cell lung cancer by targeted exome sequencing: association with longer relapse-free survival)

Contributors: EDWARD Mugambi Ireri, Mohammed Hersi Warsame

Date: 2019-10-13

... Data collection Data was collected in Nairobi county, Kasarani constituency from May 1st, 2019 to 1st June 2019. The main target group in the study were entrepreneurs who owned shops and market stalls. However, clients who were present at the shops or stalls during the interviews, were also given a chance to participate in the study. It is believed that persons with businesses would seize the opportunity to utilise the soft loans offered the various Fintech service providers in Kenya to expand their businesses. Equally, the age participation in the current study was 18 years and over. A total of 351 questionnaires were collected with the help of two research assistants who were standing by to answer any queries from the participants and thus there were no incomplete questionnaires. Nevertheless, 9 questionnaires were excluded from the study because they had unengaged responses. The final usable questionnaires were 342. Methodology The Extended Post-Acceptance model by Lim, Kim, Hur, and Park (2018) was tested using the data. Confirmatory factor analysis was performed using AMOS version 24. A 10,000 replication bootstraps was performed as one way of validating the multivariate model used in the current study. Equally, the bias -corrected confidence intervals was set at 95% confidence level. Results The finding on users’ knowledge of the services has a significant positive effect on perceived security (β =0.808, p <0.001) of short-term credit services offered by Fintech’s in Nairobi, supporting hypothesis H1. Perceived security has a significant and positive effect on confirmation (β =0.734, p <0.001) and perceived usefulness (β =0.852, p <0.001) of short-term credit services offered by Fintech’s thus supporting hypotheses H2a and H2b. Confirmation has no significant effect on perceived usefulness ((β =0.031, p = 0.786) thus rejecting hypothesis H3a. However, confirmation has a significant positive effect on satisfaction (β =0.533, p = 0.001), supporting hypothesis H3b. Perceived usefulness has a significant positive effect on satisfaction (β =0.332, p = 0.004), supporting hypothesis H4a. However, perceived usefulness has no significant effect on continuous intention to use Fintech services (β =0.003, p = 0.991), thus rejecting hypothesis H4b. User’s satisfaction has a positive effect on continuous intention to use Fintech services (β =0.593, p = 0.003). All the confidence levels where at 95%. Conclusion The study revealed that Kenyans will continue to use Fintech technologies and its credit services if they remain useful, secure, satisfactory and offer high expectation upon usage. Reference Lim, S. H., Kim, D. J., Hur, Y., & Park, K. (2018). An Empirical Study of the Impacts of Perceived Security and Knowledge on Continuous Intention to Use Mobile Fintech Payment Services. International Journal of Human–Computer Interaction, 1-13.

Contributors: Chun Shao

Date: 2019-10-13

... Date of Fig. 4, 6-7, 9-10,12-16, 18-20.

Contributors: Jianguo Gao

Date: 2019-10-13

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Contributors: Franck THIBAULT, Raul Martinez, Dionisio Bermejo, Piotr Wcislo

Date: 2019-10-13

... Supplementary material for : Line-shape parameters for the first rotational lines of HD in He By Franck Thibault, Raul Martinez, Dionisio Bermejo and Piotr Wcislo Article submitted to Molecular Astrophysics (oct. 2019). Please read the SupMat_MolecularAstrophysics.pdf file. Data for deriving line shapes parameters for the pure rotational R(0-3) and S(0-2) lines of HD perturbed by helium. Kinetic energy dependent pressure broadening and shift cross sections. Complex Dicke cross sections.. Associated speed dependent parameters at 77, 195 and room T. Thermally averaged parameters for selected temperatures between 10 and 500 K, including pressure broadening and shift coefficients and complex Dicke frequency of velocity changing collisions (nu_opt).

Contributors: Chun Shao

Date: 2019-10-13

... Date of Fig. 4, 6-7, 9-10,12-16, 18-20.