45 results for Medicni perspektivi
Contributors: Semyonova L.S., Klimenko I.N.
... This article is devoted to a well-known doctor and writer A.P. Chekhov. It shows the influence of his doctor's activity on the creative literary process and concept of humanism in his literary works.
Contributors: Zakharov S.V.
... A comparative analysis of the sensitivity and specificity of immunoblotting against other non-treponemal and treponemal reactions was carried out in 215 patients with early forms of syphilis. A high diagnostic efficiency of immunoblotting in patients with early latent syphilis was established. It was found that only in case of primary syphilis, immunoblotting is inferior to Immunofluorescence reaction; this test can be used for differential diagnosis between hidden syphilis and false positive reactions to syphilis.
Contributors: Schevchenko-Makarenko O.P., Schostakovych-Korets'ka L.R., ChykarenkoZ.O., Tkachenko V.D., Lisnicha O.O.
... The article presents the adaptation data of the quality of life questionnaire (QOL) in patients with chronic viral hepatitis C (CVHC). Ball score of QOL of patients with CVHC was 5.09±1.04, 2nd group (with co-infection with HIV / HCV) - 4.60±1.13, control group - 5.92±0.52 (p<0.05)). The results of the analysis show that co-infection HIV / HCV is a serious problem for patients and significantly affects QOL. The use of the QOL questionnaire for chronic liver disease is a sensitive tool for measuring QOL in patients with CVHC and co-infection HIV / HCV. This informative and economical method can be implemented to assess the patient's health both at the group and individual levels in patients with chronic liver disease in the population of Ukraine.
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Model for predicting long-term sinus rhythm retention after electrical cardioversion in patients with persistent atrial fibrillation
Contributors: Pysarevska K.O., Zharinov O.I.
... The aim - to create a model for predicting long-term sinus rhythm retention after electrical cardioversion (ECV) based on individual patients characteristics. 141 patients with persistent AF who were planning to have sinus rhythm restoration, underwent general clinical examination, ECG and transthoracic echocardiographic. In 6 months after ECV patients were divided into two groups: 83 patients maintained sinus rhythm for 6 months (group I), recurrence of AF was observed in 58 patients (group II). The results of the ROC analysis determined statistically significant parameters that contribute to long-term retention of the sinus rhythm: non-modifiable (age, history and duration of the last episode of arrhythmia, combination of background diseases), modifiable (smoking, antiarrhythmic therapy, severity of heart failure by NYHA). A multifactorial prognostic model is created with the help of the modern approach of creating scorecards. This allowed in the form of a numerical characteristic to determine the probability of a long retention of the sinus rhythm. The selection of factors for the scoring model was in accordance with the criteria of the power of their influence on the retention of the sinus rhythm. The scoring model was created for predicting long-term retention of sinus rhythm after electrical cardioversion based on the individual characteristics of a patient with a persistent form of AF. The model has a high sensitivity (92.77%) and specificity (70.69%) and allows to predict the further course of the disease and to correct the therapy on time.
Study of modification of zinc status of laboratory animals in conditions of low-dose action of lead and zinc in various forms
Contributors: Biletska E.M., Shtepa O.P., Kalinicheva V.V., Valchuk S.I.
... In recent years the steady trend to growth of the technogenic load of the environment closely correlates with deterioration of the health status of the population, chronic diseases and worsening of demographic indicators. One of the main threats to human health from contamination with heavy metals is associated with the influence of lead, which contributes to the development of chronic diseases of the nervous, hematopoietic, endocrine, renal and bone systems. In the process of studying the properties of zinc, its use as an osteoprotective agent is becoming more actual. In connection with the foregoing, the aim of our study was to study the content of zinc in bone tissue in low-dose isolated and combined effects of various forms of lead and zinc under the experimental conditions. For the experiment, sexually mature Wistar rats with a body weight of 150-170 g were selected, with the following randomization into six experimental and one control group, eight rats in each one. The data obtained and their comprehensive analysis allow to fully suggest the formation of a bioantagonistic relationship between lead and zinc in the bone at the level of the latter, observed both in the isolated action of lead and in combination with zinc. Along with this, our results correspond with the data of other researchers on the osteoprotective properties of zinc under the action of even low-dose levels of lead, especially of its nanoacqualate form (zinc citrate).
Characteristics of the lipid profile in patients with morbid obesity before and after surgical treatment, depending on the type of surgical intervention
Contributors: Duka R.V.
... Excessive deposition of adipose tissue in the body is often associated with dyslipidemic disorders and various risk factors for cardiovascular disease. The abdominal-visceral form is a serious predictor of cardiovascular mortality. The aim of the study was to establish the prevalence of lipid metabolism disorders in patients with morbid obesity and to evaluate the influence of surgical methods of treatment, namely biliopancreatic shunting in the Hess-Marceau modification and longitudinal gastrectomy in the postoperative period on the degree of correction of dyslipidemia in these patients. 57 patients (36 (63.2%) women and 21 (36.8%) men) with morbid obesity were in-depth examined, age from 21 to 62 years (mean age 40.0±1.38 years), who were under observation at the Department of Surgery N 1, SE "DMA". Significant violations of lipid metabolism in these patients were revealed, which significantly correlated with indicators of excessive body weight. There were established general trends towards a significant decrease (p <0.001) of body mass index and BMI in patients of both groups after 3 months from the start of treatment, which led to a significant improvement in lipid metabolism.
The role of out-of-class work of doctor-interns in improving qualitive academic progress on clinical immunology and allergology under the primary specialization "Internal diseases"
Contributors: Kuz'mina G.P., Potabashniy V.A., Fesenko V.I., Knjazjeva O.V., Azarenko V.Je., Knjazjeva O.V., Vasylenko A.M., Khatsko V.E.
... The use of independent out-of-class work of interns on the specialty "Internal diseases" in the section of clinical immunology and allergology promoted the improvement of the qualitative success of interns.
Contributors: Mavropulo T.K.
... Infants delivered at 37 and 38 weeks’ gestation are at increased risk for morbidity as compared to infants delivered at 39-40 weeks. Our objectives were to study the frequency of transient neurologic dysfunction in the first months in newborns and infants, depending on the gestational age. We found a higher incidence of risk factors of pregnancy, more frequent need in oxytherapy after birth, and differences of hemo lyquordynamics at the age of 2-3 months.
Contributors: Chorna Ju.V.
... The article examines the main aspects of postgraduate education of junior specialists with medical or pharmaceutical education in Dnipropetrovsk region. Pedagogical innovations involves active learning, competency approach and introduction of new subjects into the educational process.
Characteristics of the microvascular bed of rats' testis exposed to electromagnetic field and using immunomodulator
Contributors: Sharapova Ye.N.
... As a result at studies performed there were defined morphofunctional changes in the structyre of microvascular bed of rats’ testes, exposed to electromagnetic field during 30-45 days, later they were receiving 7% Echinacea purple tincture. It was established that in these experimental terms the structure of testicular vessels was significantly different by morphologic structure. On the day 30 in the structure of microhemocirculatory bed of testes there was defined an insignificant blood-filling of the venous bed. There were neither spasms of arteries, which formed cellular structure in the testicular tissue, no edematous signs. On the day 45 of the experiment in the testes of the irradiated rats there was noted more expressed bifurcation of arterial vessels and decrease of blood-filling of veins without expressed venous stasis. With the increase of irradiation term by electromagnetic field up to 45 days and usage of Echinacea purpura tincture there were noted reverse phenomena in hemacicrulatory bed of rats’ testes in the form of widening of arterial chain of vessels and narrowing of venons chain of the vessels; this led to increase of index of medium diameter of seminal tubules and subsequently, to the increase of the total area of spermatogenous tissue of rats.