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    <dc:creator>VILA, isabelle K</dc:creator>
    <dc:title>IP STING - Identification of new partners</dc:title>
    <dc:publisher>Mendeley Data</dc:publisher>
    <dc:description>To access STING function in absence of inflammation, given the tight interconnexion between metabolic and immune pathways, we questioned the impact of Sting ablation on metabolic parameters in vivo. Mice deficient for STING presented profound modifications of glucose management and body temperature. To identify the molecular mechanism through which Sting regulates metabolic homeostasis, we performed tandem-affinity purification of Flag- and HA-tagged Sting (F/HA-Sting) stably expressed in mouse embryonic fibroblasts (MEF) knockout for Sting (MEF Sting-/- ). Immunopurified material was analyzed by Mass Spectrometry to identify Sting protein partners.</dc:description>
    <dc:subject>Innate Immune Modulator</dc:subject>
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    <dc:identifier>oai:data.mendeley.com/23drspzh3s.1</dc:identifier>
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