2026-10-15T11:24:00Z https://data.mendeley.com/oai

oai:data.mendeley.com/3jkwnhxm36.1 2025-04-21T23:07:18Z

Oliveira Fonseca, Lorena No Thromboembolic Events Observed in RCTs of Oral Tranexamic Acid: A Systematic Review and Descriptive Synthesis Mendeley Data This systematic review synthesizes data from 51 randomized controlled trials and 23 observational studies evaluating the safety of oral tranexamic acid (TXA), with a specific focus on thromboembolic events (TEs). While TXA is widely used off-label for chronic dermatologic conditions such as melasma, concerns regarding TE risk have limited its broader adoption. Our findings reveal no thromboembolic events in over 2,500 RCT participants treated with oral TXA for durations of up to 24 months, suggesting a favorable safety profile in controlled settings. Dermatology Deep Vein Thrombosis Pulmonary Embolism Rosacea Hormonal Effect Thromboembolic Disease Melasma Systematic Review with Meta-Analysis Kuceki, Guilherme Mendez, Daniela Garza, Georgina Kruithoff, Caroline Karan, Lal Dataset doi:10.17632/3jkwnhxm36.1 oai:data.mendeley.com/3jkwnhxm36.1 Creative Commons Attribution 4.0 International http://creativecommons.org/licenses/by/4.0 https://data.mendeley.com/datasets/3jkwnhxm36 2025-04-21T23:07:18Z