2026-10-15T10:40:10Z https://data.mendeley.com/oai

oai:data.mendeley.com/fzh7pfpmmb.1 2019-07-24T01:07:46Z

Becker, Winston RISC Kinetic and Thermodynamic Data Mendeley Data We applied high-throughput methods to measure the association kinetics, equilibrium binding energies, and single- turnover cleavage rates of RISC. We find that RISC readily tolerates insertions of up to seven nucleotides in its target opposite the central region of the guide. Fit parameters for miR-21 and let-7a association, equilibrium binding, and cleavage are provided herein. These data were obtained from RNA-MaP and RISC Cleave-'n-Seq. Raw sequencing data is available on SRA. Biochemistry Dataset doi:10.17632/fzh7pfpmmb.1 oai:data.mendeley.com/fzh7pfpmmb.1 Creative Commons Attribution 4.0 International http://creativecommons.org/licenses/by/4.0 https://data.mendeley.com/datasets/fzh7pfpmmb 2019-07-24T01:07:46Z 2019-07-16T00:00:00Z