2026-10-15T09:57:04Z https://data.mendeley.com/oai

oai:data.mendeley.com/gbww9jr739.1 2026-10-12T14:14:02Z

Xu, Jinquan Transcriptome-Informed Drug Repurposing for Sepsis-Induced Acute Respiratory Distress Syndrome: A Connectivity-Map Analysis of Public Blood Cohorts Mendeley Data Reproducibility package for the study "Transcriptome-Informed Drug Repurposing for Sepsis-Induced Acute Respiratory Distress Syndrome: A Connectivity-Map Analysis of Public Blood Cohorts". Contains the complete R/Python analysis pipeline (differential expression with limma, enrichment analysis, LINCS/CMap connectivity scoring, Fisher meta-analysis, drug-target network construction, day-0 and confounder sensitivity analyses), all derived result tables backing every reported number, source figures, execution logs, renv.lock with pinned package versions, CITATION.cff, LICENSE (MIT for code; CC BY 4.0 for data/figures), MANIFEST.sha256, and README.md. Primary microarray cohorts (GSE10474, GSE32707, GSE66890) are publicly available in GEO and are not redistributed; the LINCS L1000 compound signatures were obtained from public Enrichr/CLUE resources. Bioinformatics Respiratory System Computational Biology Dataset doi:10.17632/gbww9jr739.1 oai:data.mendeley.com/gbww9jr739.1 Creative Commons Attribution 4.0 International http://creativecommons.org/licenses/by/4.0 https://data.mendeley.com/datasets/gbww9jr739 2026-10-12T14:14:02Z