2026-10-15T11:50:38Z https://data.mendeley.com/oai

oai:data.mendeley.com/hp9mfwck7k.1 2026-07-30T11:26:41Z

gündüz, kaan Supplemental Material for JAAD-D-26-01408 — Risk-Adapted Monitoring of Melanocytic Lesions With Peripheral Globules: A Longitudinal Cohort Study on Melanoma Risk Stratification Mendeley Data This dataset contains the supplemental material for the article "Risk-Adapted Monitoring of Melanocytic Lesions With Peripheral Globules: A Longitudinal Cohort Study on Melanoma Risk Stratification" (Journal of the American Academy of Dermatology; manuscript JAAD-D-26-01408), by Kaan Gündüz, MD; Handan Merve Erol Mart, MD; Ömer Faruk Şimşek, MD; İlay Özsan, MD; Murat Doğuş Günel, MSc; Ayşe Öktem, MD; Bengü Nisa Akay, MD. Per journal policy, supplemental material is hosted here rather than published with the article. Contents: - Supplementary Methods: Full modeling details, including priors, convergence diagnostics, and model-fit metrics. - Supplementary Results: Details of model convergence, patient-level heterogeneity, and out-of-sample predictive performance. - Supplementary Figure 1: Histopathologically confirmed benign melanocytic nevi with peripheral globules. Six lesions (a-f) biopsied or excised because of documented change, age-related concern, growth or persistence of peripheral globules, or clinical caution during digital monitoring; all benign on histopathology. - Supplementary Figure 2: Histopathologically confirmed melanomas presenting with peripheral globules across different age groups. Six lesions (a-f) in patients aged 22 to 78 years, including melanoma in situ and invasive melanomas (Breslow 0.3-0.8 mm), illustrating the role of globule symmetry, size and color variability, associated central structures, and patient-level melanoma risk. - Supplementary Figure 3: Sequential handheld dermoscopic images at baseline, 3 and 6 months of a lesion in a 55-year-old patient with irregular peripheral globules and central asymmetry; excision revealed invasive melanoma (Breslow 0.5 mm). - Supplementary Figure 4: Sequential handheld dermoscopic images at baseline, 3 and 6 months of a lesion in a 22-year-old woman with a family history of melanoma, showing rapid growth and a chaotic dermoscopic pattern; excision revealed invasive melanoma (Breslow 0.45 mm). - Supplementary Table 1: Comparison of lesion-level characteristics between excised and non-excised lesions. - Supplementary Table 2: Secondary analysis restricted to the 143 excised lesions, showing melanoma-specific dermoscopic structures and other independent predictors of adverse histopathologic outcome. Dermatology Nevus Dermoscopy Erol Mart, Handan Merve Şimşek, Ömer Faruk Özsan, İlay Günel, Murat Doğuş Karal, Ayşe Akay, Bengü Nisa Dataset doi:10.17632/hp9mfwck7k.1 oai:data.mendeley.com/hp9mfwck7k.1 Creative Commons Attribution 4.0 International http://creativecommons.org/licenses/by/4.0 https://data.mendeley.com/datasets/hp9mfwck7k 2026-07-30T11:26:41Z