2026-10-14T22:47:17Z https://data.mendeley.com/oai

oai:data.mendeley.com/r9878ks8nm.1 2025-02-25T10:14:27Z

de Laat, Wouter Long-range enhancer-controlled genes are hypersensitive to regulatory factor perturbations Tjalsma et al. Mendeley Data To study the contribution of regulatory factors to long-range enhancer-mediated gene regulation, we created degron cell lines for the factors RAD21, LDB1, and MED23, in human K562 cells. By endogenously tagging these proteins with a degron tag, we were able to quickly deplete them and measure their effect on gene expression using nascent RNA-sequencing. These files contain raw western blot images used to confirm that treatment of these cells with the degron ligand resulted in depletion of the tagged factors. Western Blot Dataset doi:10.17632/r9878ks8nm.1 oai:data.mendeley.com/r9878ks8nm.1 Creative Commons Attribution 4.0 International http://creativecommons.org/licenses/by/4.0 https://data.mendeley.com/datasets/r9878ks8nm 2025-02-25T10:14:27Z