2026-10-15T17:15:28Z https://data.mendeley.com/oai

oai:data.mendeley.com/s5nb3bxyjf.1 2020-10-26T16:09:28Z

fan, zhang Data for: In silico prediction of bioequivalence of Isosorbide Mononitrate tablets with different dissolution profiles using PBPK modeling and simulation Mendeley Data The research data files are compromise of 5 supplementary materials. The detailed information of clinical study is displayed in Supplementary material 1, and all simulated data in manuscript are shown in supplementary material 2-5: 1) supplementary material 1 (the detailed information of clinical study) 2) supplementary material 2 (the simulated data used for internal verification of PBPK model) 3) supplementary material 3 (the simulated data used for external verification of PBPK model) 4) supplementary material 4 (the simulated data used in the section 4.3 of manuscript) : this simulated data was used to explore whether the rapid dissolution rate (dissolved ≥ 85% in 30 min) are necessary to ensure the bioequivalence for BCS I class drug 5) supplementary material 5 (the simulated data used in the section 4.4 of manuscript) : this simulated data was used to establish a clinically relevant dissolution specification of Isosorbide Mononitrate tablets. Pharmacokinetics Pharmacokinetic Modeling Bioequivalence Dataset doi:10.17632/s5nb3bxyjf.1 oai:data.mendeley.com/s5nb3bxyjf.1 Public Domain Dedication http://creativecommons.org/publicdomain/zero/1.0/ https://data.mendeley.com/datasets/s5nb3bxyjf 2020-10-26T16:09:28Z 2021-08-07T00:00:00Z