2026-10-15T10:16:04Z https://data.mendeley.com/oai

oai:data.mendeley.com/vrpw86vx8f.4 2022-06-27T15:41:01Z

Sahin, Hakan A dataset for oxytocin loaded nanoparticles and their effects on pentylenetetrazole-kindling model of male rats Mendeley Data Temporal lob epilepsy (TLE) related to hippocampus is characterized with seizures. Memory-related cognitive abnormalities are important problems with this disorder. Pentilentetrazol (PTZ)-kindling is one of the models which is applied on rodents in order to investigate TLE. Findings for the histopathology of hippocampus are like decrease of neurogenesis, and short-time memory alterations are seen in the PTZ-kindling model which are also related to human TLE. Although exogenously application of oxytocin (OT) hormone researches are increasing for the effects of brain and related pathophysiologies, epilepsy-related studies are highly limited. According to previous data about OT application for non-invasive and efficiently passing through the brain, it is seen that intranasal (IN) pathway and OT loaded nanoparticles (NP-OTs) are prominent methods for that issue. This study aims IN administrated NP-OTs and their effects on pentylenetetrazole-kindling model of male rats This dataset includes some data of the author's master thesis found in Council of Education Thesis Center (https://tez.yok.gov.tr/UlusalTezMerkezi/giris.jsp) with the 657706 thesis number. Neuroscience Histology Nanoparticles Behavior (Neuroscience) Neurogenesis Oxytocin Animal Models of Epilepsy Yucel, Oguz Emik, Serkan Senturk, Gozde Erkanli Dataset doi:10.17632/vrpw86vx8f.4 oai:data.mendeley.com/vrpw86vx8f.4 Creative Commons Attribution 4.0 International http://creativecommons.org/licenses/by/4.0 https://data.mendeley.com/datasets/vrpw86vx8f 2022-06-27T15:41:01Z