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                <identifier>oai:data.mendeley.com/xpdxh9bvd7.1</identifier>
                <datestamp>2026-08-19T09:53:40Z</datestamp>
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    <dc:creator>Lee, Myungwoon</dc:creator>
    <dc:title>Lipid Acyl Chain-Driven α-Synuclein Fibril Polymorphisms and Neuronal Pathologies</dc:title>
    <dc:publisher>Mendeley Data</dc:publisher>
    <dc:description>Solid-state NMR spectra and microscopy images associated with the following publication:
Y. Baek, A. Alim, Y. Dong, T. Olabi, J. Paek, and M. Lee, “Lipid Acyl Chain-Driven α-Synuclein Fibril Polymorphisms and Neuronal Pathologies,” ACS Chemical Neuroscience 17 (7), 1286–1302 (2026). https://doi.org/10.1021/acschemneuro.5c00730.

lipid free_Aged_Neuron_asyn ssNMR:
Agedmem_2DCC.ucsf: 2D CC ssNMR spectra of a-syn fibrils formed in the presence of Aged mimetic neuronal membranes
Agedmem_2DNC.ucsf: 2D NC ssNMR spectra of a-syn fibrils formed in the presence of Aged mimetic neuronal membrane
Neuronmem_2DCC.ucsf: 2D CC ssNMR spectra of a-syn fibrils formed in the presence of normal mimetic neuronal membranes
Neuronmem_2DNC.ucsf: 2D NC ssNMR spectra of a-syn fibrils formed in the presence of normal mimetic neuronal membrane
lipid_free_2DCC.ucsf: 2D CC ssNMR spectra of a-syn fibrils formed without lipids
lipid_free_2DNC.ucsf: 2D NC ssNMR spectra of a-syn fibrils formed without lipids

Microscope images:
NF-kB: nuclear translocation of NF-κB
α-syn aggregation: Immunofluorescence micrographs showing differential formation of intraneuronal α-syn aggregates in response to structurally distinct α-syn PFFs and lipid conditions.
pSer 129: Immunostaining of α-syn phosphorylated at serine 129
Supporting information: Differentiation of neuroblastoma cells into dopaminergic neurons</dc:description>
    <dc:subject>Microscopy</dc:subject>
    <dc:subject>13C NMR Spectroscopy</dc:subject>
    <dc:contributor>Baek, Yoongyeong</dc:contributor>
    <dc:contributor>Alim, Anika</dc:contributor>
    <dc:contributor>Dong, Yanheng</dc:contributor>
    <dc:contributor>Olabi, Tarek</dc:contributor>
    <dc:contributor>Paek, Jungwook</dc:contributor>
    <dc:type>Dataset</dc:type>
    <dc:identifier>doi:10.17632/xpdxh9bvd7.1</dc:identifier>
    <dc:identifier>oai:data.mendeley.com/xpdxh9bvd7.1</dc:identifier>
    <dc:rights>Creative Commons Attribution 4.0 International</dc:rights>
    <dc:rights>http://creativecommons.org/licenses/by/4.0</dc:rights>
    <dc:relation>https://data.mendeley.com/datasets/xpdxh9bvd7</dc:relation>
    <dc:date>2026-08-19T09:53:40Z</dc:date>
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