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    <responseDate>2026-10-15T17:55:51Z</responseDate>
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            <header>
                <identifier>oai:data.mendeley.com/yt99rmbcdt.1</identifier>
                <datestamp>2022-05-25T13:54:12Z</datestamp>
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            <metadata><oai_dc:dc xsi:schemaLocation="http://www.openarchives.org/OAI/2.0/oai_dc/ http://www.openarchives.org/OAI/2.0/oai_dc.xsd" xmlns:oai_dc="http://www.openarchives.org/OAI/2.0/oai_dc/" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
    <dc:creator>Joyce, Johanna</dc:creator>
    <dc:title>Multimodal imaging of the dynamic brain tumor microenvironment during glioblastoma progression and in response to treatment</dc:title>
    <dc:publisher>Mendeley Data</dc:publisher>
    <dc:description>•	The deposited data have been generated by intravital imaging of glioma-bearing mice, which allows one to longitudinally track different cell types during tumor progression and response to therapy. 
•	Raw and processed data are divided into two folders, based on the cell lineage-tracing model used (either CX3CR1 or FLT3 lineage-tracing model).
•	Each folder contains the raw imaging data and an R script folder.
•	The raw imaging data consist of “Statistics”, parameters extracted after analysis with Imaris (.csv files). Each subfolder represents a specific timepoint for a unique imaging position in one individual mouse. Note that each segmented component (microglia (MG), second harmonic generation (SHG, measuring collagen), and tumor cells) have their own individual subfolder.
•	The R script folder contains 3 files: the source file containing custom functions for processing and visualization; the processing file which combines imaging- and metadata, and transforms this into a single experimental object in R; and the output file which presents the analyses and visualizations of the data. </dc:description>
    <dc:subject>Macrophage</dc:subject>
    <dc:subject>Microenvironment</dc:subject>
    <dc:subject>Brain Tumor</dc:subject>
    <dc:subject>Intravital Microscopy</dc:subject>
    <dc:subject>Magnetic Resonance Imaging of Brain Tumor</dc:subject>
    <dc:type>Dataset</dc:type>
    <dc:identifier>doi:10.17632/yt99rmbcdt.1</dc:identifier>
    <dc:identifier>oai:data.mendeley.com/yt99rmbcdt.1</dc:identifier>
    <dc:rights>Creative Commons Attribution 4.0 International</dc:rights>
    <dc:rights>http://creativecommons.org/licenses/by/4.0</dc:rights>
    <dc:relation>https://data.mendeley.com/datasets/yt99rmbcdt</dc:relation>
    <dc:date>2022-05-25T13:54:12Z</dc:date>
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