2026-10-15T11:52:37Z https://data.mendeley.com/oai

oai:data.mendeley.com/yx33pt7t4f.1 2025-11-27T07:44:34Z

Meng, Zhuo-Xian Expression data from major metabolic organs of C57BL/6J mice and MIN6 cells maintained on normal or stressed conditions Mendeley Data We studied the novel mechanism of ER quality control, ER homeostasis maintenance and functional plasticity in pancreatic β-cells to increase systemic glucose homeostasis against progression of type 2 diabetes. In RNA-Seq dataset, we provided islets' RNA-Seq for C57BL/6J wildtype mice on 2-month high-fat diet and on normal chow diet; we also provided 10 different metabolic tissues' RNA-Seq for C57BL/6J wildtype mice on normal chow diet. In proteomics dataset, we provided proteomic analysis on MIN6 cells and supernatant on normal and stressed culturing conditions; we also provided islets' proteomic analysis for C57BL/6J wildtype mice on 2-month high-fat diet and on normal chow diet; we also provided proteomic analysis for DNA-pull down-protein complex from HEK293T cells. Original computational code for image processing were deposited in this dataset. All the algorithms were implemented with OpenCV and Numpy library in Python. Algorithms Proteomics Endoplasmic Reticulum Diabetes Metabolism Next Generation Sequencing Dataset doi:10.17632/yx33pt7t4f.1 oai:data.mendeley.com/yx33pt7t4f.1 Creative Commons Attribution 4.0 International http://creativecommons.org/licenses/by/4.0 https://data.mendeley.com/datasets/yx33pt7t4f 2025-11-27T07:44:34Z