The ALPHA Network (Analysing Longitudinal Population-based HIV/AIDS data on Africa) is working on a project to produce a sharable set of harmonised data that combines both population-based and clinic data from the partner studies with funding from the Wellcome Trust. Whilst community-based cohorts and demographic surveillance systems provide a rich source of data, use of the data is often limited because successful analysis requires detailed knowledge of the study's contemporary and historical procedures and of data management practices. To date the ALPHA Network has successfully extracted and harmonised 10 standard data tables from the partner studies. However, these data are still complex and require considerable prior knowledge to use effectively, which in practice means the data can only be used in collaboration with one of the ALPHA staff.
This data collection contains qualitative data collected as part of scoping work to establish domain experts’ perspectives on the functionality that a user-friendly metadata browser for ALPHA datasets should provide. It contains transcripts of 10 semi-structured Skype interviews conducted with individual researchers and data managers affiliated to the ALPHA network and the Cohort & Longitudinal Studies Enhancement Resources (CLOSER) project. Interviews explored proposed features of the metadata browser, including: provision for viewing all tasks performed in the process of creating a dataset, browsing the steps in each task, task purpose, related concepts, related code scripts, association between a sub-task and its input data and outputs and provision for viewing data structure.
This paper introduces an expressive class of quotient-inductive types, called QW-types. We show that in dependent type theory with uniqueness of identity proofs, even the infinitary case of QW-types can be encoded using the combination of inductive-inductive definitions involving strictly positive occurrences of Hofmann-style quotient types, and Abel's size types. The latter, which provide a convenient constructive abstraction of what classically would beaccomplished with transfinite ordinals, are used to prove termination of the recursive definitions of the elimination and computation properties of our encoding of QW-types. The development is formalized using the Agda theorem prover.
UK Agriculture and Horticulture Development Board(Project CP 172)
Contributors:Carlton, J, Peasgood, T, Khan, S, Barber, R, Bostock, J, Keetharuth, A D
Patient-reported outcome measures (PROMs) are widely used in the United Kingdom (UK) and internationally to report and monitor patients' subjective assessments of their symptoms and functional status and also their quality of life. Whilst the importance of involving the public in PROM development to increase the quality of the developed PROM has been highlighted this practice is not widespread. There is a lack of guidance on how public involvement (PI) could be embedded in the development of PROMs, where the roles can be more complex than in other types of research. This paper provides a timely review and sets out an emerging framework for fully incorporating PI into PROM development.
Contributors:Lefauve, Adrien, Partridge, Jamie, Dalziel, Stuart, Linden, Paul
Laboratory experiments on the stratified shear flow in an inclined duct are reported.
Stratified turbulence is observed in this two-layer exchange flow, whose dissipation is
controlled by the duct inclination and compares in intensity with that observed in geo-
physical contexts. A setup enabling three-dimensional (3D) simultaneous Particle Image
Velocimetry (PIV) and Laser-Induced Fluorescence (LIF) is presented, and applied to the
visualisation of Holmboe waves. Such capabilities are believed to be key to advance our
understanding of the dynamics and mixing of stratified turbulence in the near future.