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  • Supplemental material, JCB914537 Supplemental Material for Comparison of Tmax values between full- and half-dose gadolinium perfusion studies by Søren Christensen, Shalini Amukotuwa, Maarten G Lansberg, Stephanie Kemp, Jeremy J Heit, Michael Mlynash, Michael P Marks, Greg W Albers and Roland Bammer in Journal of Cerebral Blood Flow & Metabolism
    Data Types:
    • Document
  • Supplemental material, 3D_memory for A Multidimensional Array Representation of State-Transition Model Dynamics by Eline M. Krijkamp, Fernando Alarid-Escudero, Eva A. Enns, Petros Pechlivanoglou, M.G. Myriam Hunink, Alan Yang and Hawre J. Jalal in Medical Decision Making
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  • Objective:This study aimed to analyze the function of metastasis suppressor 1 (MTSS1) in triple negative breast cancer (TNBC).Methods:MTSS1 expression in 30 TNBC and paracancerous tissues was measured by quantitative reverse transcriptase polymerase chain reaction. The prognostic value of MTSS1 was assessed by Kaplan–Meier analysis followed by the log-rank test. MCF7 cells were transfected with si-MTSS1, while MDA-MB-231 cells were transfected with pcDNA3.1-MTSS1. Cell proliferation assay and transwell assay were performed to investigate the effects of MTSS1 on the biological behavior of breast cancer cells. Immunofluorescence and western blot were used to detect the influence of MTSS1 on epithelial–mesenchymal transition (EMT) markers.Results:MTSS1 expression was significantly lower in TNBC tissues compared with that in paracancerous tissues (0.012 vs. 0.370; P = 0.006). A lower MTSS1 expression level was also found in tumor tissues of patients with lymph node metastasis (P = 0.002) or tumor node metastasis stage (P = 0.010). Patients with low expression of MTSS1 (⩽ 0.009) had shorter disease-free survival (47.4 vs. 56.0 months; P = 0.012). The knockdown of MTSS1 in MCF7 cells inhibited cell proliferation, enhanced cell migration and invasion capacities, decreased the E-cadherin level, and increased the vimentin level, whereas overexpression of MTSS1 in MDA-MB-231 cells had the opposite effects (P < 0.05).Conclusions:Our findings demonstrated that MTSS1 regulates proliferation, invasion, migration, and EMT in TNBC, and that decreased MTSS1 is associated with shorter disease-free survival.
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  • Supplemental Material, Supplementary_file-837002Almatouq for Turkers of the World Unite: Multilevel In-Group Bias Among Crowdworkers on Amazon Mechanical Turk by Abdullah Almaatouq, Peter Krafft, Yarrow Dunham, David G. Rand and Alex Pentland in Social Psychological and Personality Science
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  • The article examined “managing diversity for organizational efficiency.” It sought to find out the extent to which diversity management influences organizational efficiency through the management of conflict, cultural diversity, and employees’ perception of marginalization as well as teamwork and employee work attitude. The survey design was employed. A sample of 178 respondents from nine multinational companies in south-south Nigeria was employed. Research data were analyzed using structural equation modeling, with diversity management and organizational efficiency serving as latent variables. The results show that the management of cultural diversity, employees’ perception of marginalization, and conflict significantly influences diversity management. Furthermore, diversity management and teamwork significantly influence organizational efficiency. The need for managers of diverse workforces to give priority to diversity management, to ensure its effective implementation, was suggested, among others.
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  • Supplemental Material, VELO-C_Nepali for Nepali Linguistic Validation of the Velopharyngeal Insufficiency Effects on Life Outcomes Instrument: VELO-Nepali by Michael M. Lindeborg, Pramila Shakya, Bhawani Pradhan, Shiba Kala Rai, Kabita Bhattarai Gurung, Suman Niroula, Badri Rayamajhi, Hema Chaudhary, Bhagwati Gaire, Naina Mahato, Lila Rana, Phana Rokaya, Nilam Shrestha, Renuka Shrestha, Januka Tamang, Hemanta Dhoj Joshi, Pushpa Gaha, Dhana Kumari Khorja, Carole D. Mitnick, Shankar Man Rai and David A. Shaye in The Cleft Palate-Craniofacial Journal
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    • Document
  • Supplemental material, JCB912405 Supplemental Material3 for Sonic hedgehog is expressed in human brain arteriovenous malformations and induces arteriovenous malformations in vivo by Igor Giarretta, Carmelo L Sturiale, Ilaria Gatto, Simone Pacioni, Eleonora Gaetani, Angelo Porfidia, Alfredo Puca, Ivana Palucci, Paolo Tondi, Alessandro Olivi, Roberto Pallini and Roberto Pola in Journal of Cerebral Blood Flow & Metabolism
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  • Supplemental material, DS_10.1177_0022034520908594 for Indigenous Microbiota Protects against Inflammation-Induced Osteonecrosis by D.W. Williams, H.E. Vuong, S. Kim, A. Lenon, K. Ho, E.Y. Hsiao, E.C. Sung and R.H. Kim in Journal of Dental Research
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    • Document
  • nligeset for Intergenerational Income Elasticities, Instrumental Variable Estimation, and Bracketing Strategies by Pablo A. Mitnik in Sociological Methodology
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    • Dataset
  • Supplemental material, JEPPD_AWE_PRISMA_2009_checklist for Nonsurgical radiologic intervention for management of abdominal wall endometriosis: A systematic review and meta-analysis by Adela G Cope, Deepa M Narasimhulu, Zaraq Khan, Wendaline M VanBuren, Brian T Welch and Tatnai L Burnett in Journal of Endometriosis and Pelvic Pain Disorders
    Data Types:
    • Document