Repository of design files for the HardwareX article titled "A low-cost and customizable alternative for commercial implantable cannula for intracerebral administration in mice".
Contributing authors: Rogneda B Kazanskaya, Alexander V Lopachev, Tatiana N Fedorova, Raul R Gainetdinov, Anna B Volnova.
Abstract: Stereotaxic intracerebral cannula implantation for neuroactive agent administration is a wide-spread method for chronic experiments requiring bypassing the blood-brain barrier in rodents. However, commercially available cannula are bulky and may interfere with animal movement or lead to their dislodging during grooming. As the number of cannula needed in one experiment, and the accompanying costs can be high, it is in the interest of researchers to produce them on their own. Custom cannula manufacturing also offers the flexibility of different cannula lengths, which is required for agent delivery to various brain structures. In this article we present a protocol for making guide cannula along with the accompanying systems required for injection, which are small, cost-effective, light, easy to make, reusable, and can be made from easily procured materials.
Contributors:David Saceda-Corralo, Virginia Velasco Tamariz, Elena de las Heras, Sergio Vañó, Cristina Pindado
Supplemental figures of TRICHOSCOPIC FINDINGS OF DISCOID LUPUS ERYTHEMATOSUS ALOPECIA: A CROSS-SECTIONAL STUDY (an article in JAAD Journal). Brownish discolotation and follicular plugging in lupus alopecia.
Supplementary Figure 1. 3-mm punch biopsy specimen taken from affected scalp showing diffuse miniaturization of hair follicles with adjacent full-sized sebaceous glands [hematoxylin and eosin, original magnification (a) x 100; (b) x 200].
Contributors:Noritsune Kawaharada, Lennart Thimm, Friedrich Dinkelacker
Cavitation inside fuel injection nozzles affects the atomization process of injected liquids. It is necessary to understand and model the process for realizing an appropriate injection strategy for an efficient combustion. As the nature of the fuel injector, it has contraction, divergent and bending parts from small to large scale. These geometrical characteristics of the nozzle have an effect on the cavitation phenomena even if it is kind of a small manufacturing variation. However, a simultaneous contained database for the transient cavitation structure especially inside the real-scale nozzle and the nozzle geometry has not been established well. Therefore, parametric investigations have been done on our manufactured transparent nozzles. And the results will be shared step by step for the cavitation model evaluations and developments.
In this database, the results in below on each nozzle are uploaded.
1. High speed imaging of the transient cavitation structure.
2. Nozzle geometry which modified as close as the measured shape.
3. Samples of mesh files and simulation results (PDF).
The purpose of this database is to provide the data to someone who intends to understand and model the cavitation phenomena. This research work is financially supported by German Research Foundation (Deutsche Forschungsgemeinschaft, DFG) within the project DI 591/29-1.
First of all, please read "About_this_database.pdf".
Here are the data and the codes used in Hiramoto&Cline (2020). Imaris image data, Matlab code, and data in mat or fig (with metadata) files are provided. These Matlab codes require a statistic toolbox.