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  • This work presents the synthesis, structural investigation and some properties of a new PLA-Siloxane-PEO hybrid presenting covalent bonds between polymers and siloxane nanoparticles.The structural features, thermal properties and chemical stability of this biocompatible system have been studied by Fourier-Transform Infrared Spectroscopy (FTIR), Raman Spectroscopy, 29 Si Nuclear Magnetic Resonance (NMR), Scanning Electron Microscopy (MEV), X-Ray Diffraction (XRD), Small-Angle X-ray Scattering (SAXS), Thermogravimetric Analysis (TGA) and Differential Scanning Calorimetry (DSC). SEM and SAXS measurements showed that the siloxane nodes act as crosslinks between the polymer chains promoting miscibility between PLA and PEO. FTIR, Raman XRD, DSC and TGA results evidenced that presence of the siloxane nanoparticles diminishes crystallinity of both polymers and increases their thermal resistance. The same techniques also showed that the high miscibility between polymers in this system enhances PLA thermal stability and prejudices PLA crystallization. Among the absence of brittleness due to the low crystalline character of PLA, this new material exhibits a fantastic resistance to PLA degradation in aqueous medium, attributed both to the presence of the siloxane particles acting as a barrier towards water diffusion and to the hydrophilic PEO segments which may attract water molecules, preventing PLA hydrolysis. All these characteristics open amazing perspective for use of this hybrid material in biological and pharmaceutical applications.
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  • IQR, interquartile range; no, number; SD, standard deviation; In total, 103 patients used systemic immunomodulating therapy after starting dupilumab. Eighteen of these patients were using systemic immunomodulating therapy from start dupilumab till study cut-off point: ciclosporin (n=6), azathioprine (n=2), methotrexate (n=4), mycophenolic acid/mycophenolate mofetil (n=3), systemic corticosteroids (n=3). Two patients stopped for respectively 14 and 33 days with systemic corticosteroids treatment and then restarted with systemic corticosteroids which they were still using at the end of study. This table displays the 83 patients that discontinued systemic concomitant immunomodulating therapy during the study.
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  • Est., estimated; SE, standard error; EASI, Eczema Area and Severity Index; IGA, Investigator Global Assessment; NRS, Numerical Rating Scale; DLQI, Dermatology Life Quality Index; POEM, Patient-Oriented Eczema Measure; Estimated scores/changes are based on our linear mixed-effects models; Significant results are presented in bold face; a Threshold coefficients for IGA: 0|1 -8.5 (SE 1.1), 1|2 -5.5 (1.1), 2|3 -2.3 (1.1), 3|4 0.7 (1.1), threshold coefficients for NRS mean 7 days: 0|1 -6.7 (SE 1.1), 1|2 -4.9 (1.1), 2|3 -3.6 (1.1), 3|4 -2.5 (1.1), 4|5 -1.8 (1.1), 5|6 -1.1 (1.1), 6|7 -0.2 (1.1), 7|8 1.0 (1.1), 8|9 2.3 (1.1), 9|10 3.8 (1.1), threshold coefficients for NRS peak 24 hours: 0|1 -9.4 (SE 2.0), 1|2 -7.7 (2.0), 2|3 -6.5 (2.0), 3|4 -5.4 (2.0), 4|5 -4.7 (2.0), 5|6 -4.2 (2.0), 6|7 -3.3 (2.0), 7|8 -2.3 (2.0), 8|9 -0.91 (2.0), 9|10 0.96 (2.0); b Registered in the Amsterdam UMC only.
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  • Data used in the manuscript submitted to GRL with title of "Study on the measurement of isoprene by Differential Optical Absorption Spectroscopy"
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  • raw data: Thermoelectric behavior in half-Heusler compounds RENiSb (RE = Sc, Dy, Er, Tm, Lu): high mobility ratio between majority and minority charge carriers
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  • This dataset includes computer games-based EEG signals. They are collected from 28 different subjects with wearable and portable EEG device called 14 channel Emotiv Epoc+. Subjects played emotionally 4 different computer games (boring, calm, horror and funny) for 5 minutes and totally 20 minutes long EEG data available for each subject. Subjects rated each computer game based on the scale of arousal and valence by applying SAM form. We provided both raw and preprocessed EEG data with .csv and. mat format in our data repository. Each subject's rating score and SAM form are also available. The aim of this dataset is to provide an alternative data for emotion recognition process and show the performance of wearable EEG devices against traditional ones. In the main folder (GAMEEMO) researches will find 29 different folders (28 for subjects and 1 for gameplay). S01, S02, ... represents the subjects who participated in the experiment. Gameplay folder shows the gameplay of each game. In each subjects folder, researchers will find preprocessed EEG data, raw EEG data csv and .mat format. Also SAM ratings are available with .pdf format. Games are represented as G1, G2, G3, and G4. G1 refers Game 1, G2 refers G2, and so on.
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  • Complete data set.
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  • Simulations files for 3D DFN for use with dfnWorks (dfnworks.lanl.gov). Accompanying manuscript submitted to Water Resources Research "Flow Channeling in Fracture Networks: Characterizing the Effect of Density on Preferential Flow Path Formation"
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  • "Every joke has a target and therefore every joke has the potential to be cruel or hurtful. It also has the opposite" said Rob Gee. Comedy is the best source for telling and informing others about what happened in society and what would be expected from society. It is also concluded that participants who watch acknowledging comedy programs are more politically aware and feel more informed than others. It is concluded there is a positive relationship between a knowledge giving political program and participant perception and understanding about political party manifesto.
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  • Raw data for Bruhn et al., 2020 (The Rad53CHK1/CHK2-Spt21NPAT and Tel1ATM axes couple glucose tolerance to histone dosage and subtelomeric silencing)
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