Filter Results
1307 results
Excel sheets, Stata do files and other resources related to the 2020 article in Demography Pathways to Low Fertility: 50 Years of Limitation, Curtailment, and Postponement of Childbearing by Ian Timæus and Tom Moultrie.
Data Types:
  • Collection
Proteomics datasets, presented as a set of tables, produced as part of Dr Ryan Henrici's PhD project (completed 2018). Version 2.0 represents an updated version as accepted for publication by mBio in January 2020.
Data Types:
  • Collection
The MS Excel file provides Muskoka2 estimates of aid for reproductive, maternal, newborn, and child health (RMNCH) over the period 2002-17 as reported in Dingle et al (2020). The Excel file includes the main reported figures, and the analyses, data, and assumptions underlying the reported figures. The Muskoka2 method responds to donors' and other stakeholders' request for a single, agreed method which produces accurate, predictable, transparent and up-to-date estimates that can be used for analyses from both donor and recipient perspectives. Future iterations of the Excel workbook will provide additional user-friendly guidance and updated estimates.
Data Types:
  • Collection
This dataset was created as part of a prioritisation exercise on wasting prevention. Data was collected via a survey on SurveyMonkey. Respondents were invited to participate via different platforms.
Data Types:
  • Collection
The central role that erythrocyte invasion plays in Plasmodium falciparum survival and reproduction makes this process an attractive target for therapeutic or vaccine development. However, multiple invasion-related genes with complementary and overlapping functions afford the parasite the plasticity to vary ligands used for invasion, leading to phenotypic variation and immune evasion. Overcoming the challenge posed by redundant ligands requires a deeper understanding of conditions that select for variant phenotypes and the molecular mediators. While host factors including receptor heterogeneity and acquired immune responses may drive parasite phenotypic variation, we have previously shown that host-independent changes in invasion phenotype can be achieved by continuous culturing of the W2mef and Dd2 P. falciparum strains in moving suspension as opposed to static conditions. Here, we have used a highly biologically replicated whole transcriptome sequencing approach to identify the molecular signatures of variation associated with the phenotype switch. The data show increased expression of particular invasion-related genes in switched parasites, as well as a large number of genes encoding proteins that are either exported or form part of the export machinery. The genes with most markedly increased expression included members of the erythrocyte binding antigens (EBA), reticulocyte binding homologues (RH), surface associated interspersed proteins (SURFIN), exported protein family 1 (EPF1) and Plasmodium Helical Interspersed Sub-Telomeric (PHIST) gene families. The data indicate changes in expression of a repertoire of genes not previously associated with erythrocyte invasion phenotypes, suggesting the possibility that moving suspension culture may also select for other traits.
Data Types:
  • Collection
ICD10 codes and matched Read codes for incompletely specified cancers and cancer sites that they encompass (limited to 20 most common cancers).
Data Types:
  • Collection
Read and mapped ICD-10 codes for Cancer diagnoses, history and care events.
Data Types:
  • Collection
Read codes for Urticaria
Data Types:
  • Collection
ICD-10 codes for Urticaria.
Data Types:
  • Collection
ICD-10 codes for Vitiligo, a disease that causes the loss of skin colour.
Data Types:
  • Collection
3