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Different human linker histone (H1) variants are expected to have distinct binding modes to the nucleosome. The position and orientation of a number of different H1 globular domains on the nucleosome were investigated through molecular docking using MGLTools and HADDOCK. The nucleosome core and linker DNA in the GH5-chromatosome structure (PDB: 4QLC) were used as a docking template. GH5 (in PDB: 4QLC) was re-docked to this template to test the docking algorithm. Docked and re-docked GH5 compared well. The docking algorithm was further tested by docking the NMR solution structure of the globular domain of chicken H1 (GH1, PDB: 1GHC) to the nucleosome template. The position of docked GH1 on the nucleosome agreed with literature. 
The N-terminal - and globular domain H1x hybrid (NGH1x) was studied using solution NMR in both low (20 mM sodium phosphate, pH 7.0) and high (20 mM sodium phosphate, 1 M sodium perchlorate, pH 7.0) ionic strength conditions (de Wit, H., Vallet, A., Brutscher, B. et al. Biomol NMR Assign (2019) 13: 249. https://doi.org/10.1007/s12104-019-09886-x). These low and high ionic strength structures were docked to the nucleosome template. 
Homology (MODELLER) and ab initio modeling (CS-ROSETTA) were employed to model structures for other human H1 globular domains: GH1.0, GH1.4, GH1oo, and GH1t. The modeled structures were also docked to the nucleosome template.
 All the docking procedures listed above produced 100 models of different energies. In each case, the lowest energy docked model was chosen. The structures of all the H1 globular domains that were docked to the template are given as PDB files (1GHC_lowest_energy.pdb; 2LSO_lowest_energy.pdb; GH5_re-docked_position.pdb; NGH1x_high_salt_NTD.pdb; NGH1x_low_salt_NTD.pdb; modeled_GH1_0_lowest_energy.pdb; modeled_GH1_4_lowest_energy.pdb; modeled_GH1oo_lowest_energy.pdb; modelled_GH1t_lowest_energy.pdb) in the data file. The nucleosome template structure is also given in PDB file format (4QLC_nucleosome_without_GH5.pdb). Finally, the docked models are also given (GH5-chromatosome.pdb; 1GHC-chromatosome.pdb; 2LSO-chromatosome.pdb; GH1_0-chromatosome.pdb; GH1_4-chromatosome.pdb; GH1oo-chromatosome.pdb; GH1t-chromatosome.pdb; NGH1x_no_salt-chromatosome.pdb; NGH1x_salt-chromatosome.pdb). The files are compatible with most molecular graphics software. The file Dockings_modelling_test_and_results.pdf provides the modeling and docking results in figures and tables. A short description of each figure and table is given within the PDF file.
Data Types:
  • Sequencing Data
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  • Document
Even though partisan cues are widely recognized as a primary force shaping voter behavior in a referendum, their effect on a decision whether to attend or abstain from voting has not yet been carefully studied. Our analysis of the pre-referendum survey data gathered before the 2015 citizen-initiated referendum in Slovakia leads to two important conclusions: First, parties’ recommendations whether to attend or abstain from voting influence voters’ behavior in a similar fashion as their suggestions for which side to vote for. Moreover, in certain institutional settings, the partisan cues related to mobilization have an even stronger impact on voters than endorsements for who or what to vote for. Second, the provided party recommendations must be unambiguous and clear. Lower clarity cues are reflected in voters’ behavior to a lesser extent. Note: Data is originally collected by the FOCUS Agency (in Slovakia) on demand of the Daily SME. All the essential information could be found in the .xlsx file.
Data Types:
  • Software/Code
  • Tabular Data
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Supplementary materials for publication JAAD-D-19-02716 (Lim et al. Novel Mutations Identified by Whole Exome Sequencing in Acral Melanoma. J Am Acad Dermatol. 2020) Supplementary Appendix 1: Detailed methods Supplementary Appendix 2: Clinical details of 31 acral melanoma patients including 7 nail apparatus melanoma patients Supplementary Appendix 3: Single nucleotide variations and small indels identified through WES Supplementary Appendix 4: Several genes whose mutations were repeatedly detected in this study and previously reported in the literature in association with melanoma Supplementary Appendix 5: Previous studies on the association of CSMD3 and EHMT1 with malignancies
Data Types:
  • Tabular Data
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  • Document
The descriptive data presented in this article is used to measure the level of student’s satisfaction with university facilities which are provided by the university as well as the government. This study involved 280 respondents comprising diploma, bachelor degree and post graduate student at Malaysian Public University. An open-ended question with 10 Likert Scale was distributed to respondents to identify the level of student’s satisfaction with the facilities provided by the university. The one to 10 scale measurements starting with one is Strongly Dissatisfied to 10 is Strongly Satisfied has been used to measure the level of student’s satisfaction towards 14 facilities at the university.
Data Types:
  • Tabular Data
  • Dataset
  • Document
  • Text
Data and R-script corresponding to the article of Fayard et al. "Magnitude and direction of parasite-induced phenotypic alterations: a meta-analysis in acanthocephalans"
Data Types:
  • Software/Code
  • Tabular Data
  • Dataset
Explanation and description of the microscopic data of mice tissue histology under concern by the Editor's of Plos One
Data Types:
  • Dataset
  • Document
  • File Set
This file contains a prototype semi-structured interview questionnaire that was used for cross country synthesis on the subject of post-disaster reconstruction and resettlement
Data Types:
  • Dataset
  • Document
As a part of a research into new techniques for purifying recycled aluminium alloys, a novel electromagnetic apparatus had been developed for investigating in real-time the separation mechanisms of detrimental inclusions in aluminium alloy melts under alternating magnetic fields. The magnetic coil was designed based on the Helmholtz coil design. A viewing gap was designed for in-situ imaging studies using synchrotron X-rays. The gap was designed to maintain a uniform magnetic field in the central region where a sample is positioned. The current setup for the magnetic coil pair is able to produce a peak magnetic flux density of ~10 mT at a frequency of 25 kHz. A separate electrical resistance furnace, designed to concentrically fit within the magnetic coils, was used to control the heating (up to ~850°C) and cooling of the samples. After a series of systematic tests and commissioning, the apparatus was used in a number of in-situ and ex-situ experiments.
Data Types:
  • Tabular Data
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  • Document
This dataset contains the primary data used in: "Multi-epoch X-ray burst modelling: MCMC with large grids of 1D simulations", Johnston et al. (2020). In this work, we interpolated and sampled a grid of 3840 KEPLER burst models using Markov Chain Monte Carlo (MCMC) methods to produce posterior distributions for the system parameters of the "Clocked Burster", GS 1826-238. Provided here is the full burst model grid and the raw MCMC sample chains. More details on the files, and how to load them, are provided in README.md
Data Types:
  • Software/Code
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  • Text
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Supplementary data supporting the manuscript updated with 4 donor results to replace the previous dataset from one donor
Data Types:
  • Dataset
  • Document
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