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Sequences of 15 keratin proteins (i.e., KRT31-36, KRT38-KRT40 and KRT81-84 and KRT86) were downloaded from Uniprot database (version 2016.05.10) and edited to generate a variant keratin protein sequence database. Each variant protein sequence contained a single SAP derived from a nsSNP with a frequency >0.1% in populations of European and African American descent, as listed in the National Center for Biotechnology Information (NCBI) SNP database (http://evs.gs.washington.edu/EVS/).
Data Types:
  • Sequencing Data
  • Dataset
miR-218-2 global knockout nucleotide sequences
Data Types:
  • Sequencing Data
  • Dataset
In this study, the COL7A1 on-target (exon 73) was analysed for precise CRISPR/Cas9 activity. NGS data was assessed in CRISPR/Cas9-treated immortalised patient keratinocytes Despite high on-target activity, high homgeneity of DSB repair outcomes was observed at the nuclease target site. This should result in efficient reframing of the gene, with minimal divergence from the wild-type sequence.
Data Types:
  • Sequencing Data
  • Dataset
The H. contortus genome assembly, gene annotation, and spliced transcripts used in Rezansoff et al.
Data Types:
  • Sequencing Data
  • Dataset
Translocations can be used as an effective conservation tool to combat the loss of genetic diversity often experienced by small and isolated populations. Mixing animals from multiple genetically diverged sources in one method to optimize genetic diversity in translocated populations. However, admixture as a conservation tool is rarely utilized due to the risks of outbreeding depression. Using single nucleotide polymorphisms (SNPs) and life history data (capture-mark-recapture), this data was used to investigate the genetic and fitness consequences of admixing two genetically distinct subspeices of burrowing bettong (Bettongia lesueur) as described in the paper by Rick et al.: Population genomics of Bettongia lesueur: admixing increases genetic diversity with no evidence of outbreeding depression.
Data Types:
  • Sequencing Data
  • Tabular Data
  • Dataset
The data products derived and presented in the manuscript of "Venusian cloud distribution simulated by a general circulation model" to Journal of Geophysical Research - Planets. *.grd file is grads format file and *.ctl file is control file of grads data. The detail of the data is given by Sugimoto et al. (2014a and 2014b) and Takagi et al. (2018).
Data Types:
  • Software/Code
  • Sequencing Data
  • Dataset
The 28S rRNA genes alignment of several Trematoda families for investigation of the phylogeny of the Xiphidiata incertae sedis, including Caudotestis dobrovolski n. sp., see: Sokolov S., Lebedeva D., Shchenkov S., Gordeev I. Caudotestis dobrovolski n. sp. (Trematoda, Xiphidiata) in North Pacific scorpaeniform fish: a crisis of concept of the opecoelid subfamily Stenakrinae Yamaguti, 1970
Data Types:
  • Sequencing Data
  • Dataset
We analyzed the collection of heteropteran hosts (907 specimens from 138 species and 23 families) captured in Papua New Guinea (PNG), a well-known biodiversity hotspot with a considerable number of endemic species of macroorganisms, for the presence of trypanosomatids, the prevalence of infection and host specificity. In addition to discovery of numerous new parasite species, some of which may represent new trypanosomatid genera, we recorded new insect hosts for the widespread trypanosomatid species and revealed potential cases of host-parasite coevolution. Attached is the alignment of sequences used in our assay of trypanosomatid diversity in PNG. In total, 185 trypanosomatid 18S rRNA sequences (147 retrieved from the GenBank and 38 representing typing units unique for PNG) were aligned using MAFFT v. 7.4. Alignment trimming was not performed in order to preserve differences between closely related species.
Data Types:
  • Sequencing Data
  • Dataset
Two sequence pairs (Forward and Reverse sequencing) from RPO and ITS genes for instance were uploaded.
Data Types:
  • Sequencing Data
  • Dataset
Sequencing of GBA1 (all exons) and LRRK2 (Exon 31 and 41) for all lines included in the manuscript: LRRK2 kinase activity regulates lysosomal glucocerebrosidase in Parkinson's disease pathogenesis. We do not observed unexpected point mutations in these genes in non-mutant cell lines.
Data Types:
  • Other
  • Sequencing Data
  • Dataset
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