Contributors:Azzaz, Nabil A. E., Hassan, Ramadan, A., Alshebly, Ali, M.
Liver diseases have become a major global health challenge and may be triggered by several toxic chemicals, which include chemotherapeutic agents, thioacetamide, H2O2, certain antibiotics, excessive alcohol consumption, and pathogenic microbes. Hence, safeguarding a healthy liver is vital for good health and well-being. Chicory (Cichorium intybus) belongs to Asteraceae Family and is considered very important medicinal plant in this direction. The present study deals evaluation methanolic extracts of Chicory plant for a period of 45 days at the following dose levels; 50 and 75 mg/kg body weight/day, orally respectively. The activities were studied by assaying aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), total and direct bilirubin (TB)and (DB), total protein (TP), albumin (Alb), catalase (CAT) and Superoxide dismutases (SOD). The methanolic extract of Cichorium intybus at dose 75 mg/kg body weight/day has the highest effectiveness against H2O2- induced hepatotoxicity.
Contributors:Tania Panayiotou, Giannis Savva, Ioannis Tomkos, Georgios Ellinas
Dynamic network slicing has emerged as a promising and fundamental framework for meeting 5G’s diverse use
cases. As machine learning (ML) is expected to play a pivotal role in the efficient control and management of
these networks, in this work, we examine the ML-based quality-of-transmission (QoT) estimation problem under
the dynamic network slicing context, where each slice has to meet a different QoT requirement. Specifically, we
examine ML-based QoT frameworks with the aim of finding QoT model/s that are fine-tuned according to the
diverse QoT requirements. Centralized and distributed frameworks are examined and compared according to
their model accuracy, routing and spectrum allocation (RSA) accuracy, and CPU (training time) and RAM (memory)
requirements.We show that the distributed QoT models outperform the centralized QoT model in accuracy
and CPU usage. The RSA accuracy, i.e., measuring the accuracy of the models with regard to the QoT-aware RSA
decisions, is sufficiently high for both frameworks. Regarding the RAM usage, as the distributed framework has
to train in parallel several QoT models, it may require higher memory, especially as the number of diverse QoT
requirements increases. This memory, however, tends to be reserved for a shorter period of time. Moreover, this
work develops a dynamic multi-slice QoT-aware (RSA) framework that integrates the ML-based QoT models.
The aim is to examine the network performance when the diverse QoT models are considered, as opposed to the
state-of-the-art single-slice QoT-aware RSA approach where all connections/slices are provisioned according to a
single QoT requirement. We show that the multi-slice QoT-aware RSA approach significantly improves network
performance, a clear indicator that the commonly considered single-slice QoT-aware RSA approach may lead to
Aqueous extract of Thevetia peruviana leaves were investigated as corrosion inhibitor for API 5L X80 pipeline steel in 1M H2SO4 solution using electrochemical and gravimetric techniques. The results reveal that T. peruviana inhibited the X80 pipeline steel corrosion in the acid medium in a concentration dependent manner. Potentiodynamic polarization results showed T. peruviana to be a mixed type inhibitor in 1M H2SO4 environment, whereas the impedance results revealed adsorption of the inhibitor species on the steel surface. The gravimetric results reveal that the adsorption mechanism of the inhibitor on the steel surface was chemisorption. The adsorption was in accordance with Freundlich adsorption isotherm and negative standard adsorption energy (Δ𝐺o𝑎𝑑𝑠) obtained inferred that the adsorption was spontaneous and the interaction between the inhibitive molecules was found to be repulsive. Scanning electron microscopy (SEM) confirmed the formation of adsorbed film on the X80 pipeline steel surface. Results revealed that T. peruviana has potential to inhibit the correction and could possibly be used for corrosion inhibition in the acidic environment of steel.
Contributors:Keating, Joseph N, Sansom, Robert S, Sutton, Mark D, Knight, Christopher G, Garwood, Russell J
Supplementary data from the following publication:
Keating, J.N., Sansom, R.S., Sutton, M.D., Knight, Chris G., and Garwood, R.J. Morphological phylogenetics evaluated using novel evolutionary simulations. Systematic Biology.
This comprises: exemplar outputs from both the TREvoSim and MBL2017 software; the R functions employed herein for node-based distance measures; the scripts used for analysis for this study; output codes for the current study for use with the TREvoSim logging system, and the modified source code for the USPR software used herein.
USPR was coded by Chris Whidden and Frederick Matsen, and published under a GNU liscense. The software is described in the following publication:
Whidden C., Matsen F. 2018. Calculating the Unrooted Subtree Prune-and-Regraft Distance. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 16(3):898–911.
Contributors:Azzaz, Nabil A. E., Hassan, Ramadan, A., Sahar, E. Hamed, Ahmed, M. Al Rifaie
Moringa oleifera is known by miracle tree. It has many advantages which make it used as medicinal herb in relieving many diseases. The antioxidant and hepatoprotective activities of Moringa oleifera leaves extracts were investigated against H2O2- induced hepatotoxicity in albino rats. Hepatotoxic rats were treated with methanolic and aqueous extracts of Moringa oleifera for a period of 45 days at the following two doses; 150 and 250 mg/kg body weight/day, orally. Aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP), total bilirubin, total protein and albumin in Plasma, Gamma-glutamyl transpeptidase (GGT) and catalase (CAT) were studied. The methanolic extract was the most effective against H2O2- induced hepatoxicity. The treated hepatoxicity rats showed upturn in all parameters. AST was decreased from 145 to 40 U/L, ALT from 154 to 37 U/L, ALP from 337 to 113 U/L, Alb was increased from 2.8 to 3.9 g/dl, Total protein from 4.8 to 6.28 g/dl, Gamma GT from 149 to 50 U/L and Total bilirubin from 1.97 to 0.78 mg/dl, and oxidative stress parameters. Catalase was increased from 1.94 to 3.04 U/.Results suggest that the antioxidant and hepatoprotective activities of Moringa oleifera leaves are possibly related to the free radical scavenging activity which might be due to the presence of total phenolics and flavonoids in the extract and the purified compounds Apigenin, P- hydroxy benzoic acid, Cateachin and rutin which were found in methanolic extract of Moringa oleifera leaves.
Contributors:Luma S. Al Banna, Nidá M. Salem, Gharam A. Jaleel, Akl M. Awwad
Sulfur nanoparticles (S-NPs) were prepared using rosemary (Rosmarinus officinalis) leaves aqueous extract and sodium thiosulfate pentahydrate (Na2S2O3.5H2O) at room temperature. The S-NPs were characterized by UV–visible spectrophotometer, Fourier transform infrared (FT-IR), Scanning electron microscopy (SEM), Transmission electron microscopy (TEM), and X-ray diffraction (XRD) techniques. The sulfur nanoparticles are crystalline in nature with average size of 40 nm. The morphology of S-NPs could be controlled by tuning the amount of rosemary leaves aqueous extract and sulfur ions. The cytotoxic effects of the S-NPs on hatching of second stage root-knot and mortality of second stage of root-knot nematode (Meloidogyne javanica) were tested. These results confirmed that the S-NPs synthesized using rosemary leaves aqueous extract and could possibility be used as anti-nematocide to manage M. javanica infestation.
Traditional game learning development module to provide an alternative game so that students
are not bored in the learning process. This research aims to develop a module to develop
teaching materials for traditional sports games in the form of books as a medium for the
implementation of learning services for traditional sports games for students of primary school
number 1 Lemah Putro in physical education in sports and health. Data collection techniques
using a questionnaire for experts and students and analyzed using a data analysis test using an
independent sample t test. The results of this study indicate that the questionnaire from the large
group field test obtained a significant value of 85.37%. Thus it can be concluded that the
treatment of the dependent variable shows that as many as 8 games which are research products
in the form of caring models focus on developing the value of caring giving effect to changes in
the value of caring for school children.
Contributors:Santoso, Danang Ari, Setiabudi, Moh. Agung
The Tug of war is a popular traditional game in Indonesia. This game is played in many society
and in many community occasional such in Indonesian independence day. The game aspects of
benefits, both in terms of social as well as physical activities or sports This game is also played
around the world and played by children and adults. Tug of war is played by two groups that
connected with a rope. Each group pull the rope up to beyond a predetermined limit. The
physical activities during the game can cause several kinds of injuries especially skin injury,
muscles and bones. This article is aimed to analyze the physical of tug of war with mathematical
model based on existing physical phenomenon. The model is contruct by assuming the Tug of
war as two objects connected with a rope. The analysis is done by consideration of the forces
acting in the model. The analysis result shows agreement with references.
Contributors:Zakeri, Zohreh, Mansfield, Neil, Sunderland, Caroline, Omurtag, Ahmet
There are 31 participants, and the data collected in our lab (MAE104 – Clifton, Nottingham Trent University) from Oct 2018 to Dec 2018.
We used our devices which are EEG, fNIRS for recording physiological data, and laparoscopic trainer box to perform basic laparoscopic tasks.
The laparoscopic tasks are the Ring Transfer and Threading tasks. The Ring Transfer task involved grasping, lifting and relocating rings from one rod to another using both surgical instruments and was performed on a ring stack base (Inovus Medical, St Helens, UK). Four rods were selected and labelled A, B, C and D, at the left-hand bottom, top left-hand, top right-hand and bottom right-hand corners on the ring stack base respectively. Four rings were initially put over rod A at the beginning of the trial. The procedure includes picking up a ring from rod A and placing it onto rod B with the left-hand only. After transferring all four rings to rod B, participants used their left-hand only to grasp and lift up each ring, pass it to the right-hand and place it on rod C. The procedure was completed by moving the rings individually from rod C to D using the right-hand only.
Threading task consisted of passing a piece of string through the holes in a pre-determined order. The holes were labelled 1-7 in a zigzag pattern on the Threading base. Participants could use both surgical tools, however, no restriction was made on the use of right, left or both hands.