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  • This in silico study evaluated the binding affinities of some natural products (resveratrol, xylopic acid, ellagic acid, kaempferol, and quercetin) to human angiotensin converting enzyme 2 and coronavirus (SARS-coV-2) main protease compared to chloroquine, an inhibitor known to prevent the cellular entry and replication of coronavirus. The respective binding energies of the selected natural compounds, and chloroquine were towards the proteins were computed using Pyrex Virtual Screening tool. The pharmacodynamic and pharmacokinetic attributes of the selected compounds were predicted using admetSAR. The molecular docking analysis showed the natural compoundshad the better scores towards the selected protein compared to chloroquinewith polar amino acid residues present at the binding sites.The predicted ADMET properties revealedthe natural products lower acute oral toxicity compared to chloroquine. The study provided evidence suggesting that the relatively less toxic natural compounds could be repositioned as anti-viral agents to prevent the entry and replication of SARS-CoV-2.
    Data Types:
    • Dataset
    • Document
  • This dataset is collection of hardness and residual stress measurement result of UNSM treated various nickel based alloys
    Data Types:
    • Tabular Data
    • Dataset
  • This dataset comprehends data and and associated R code used to run the analysis for the paper. We also include an R Markdown Dynamic document. We tested whether the amount of melanomacrophages and hepatic cellular catabolism substances are influenced by land use changes in the Brazilian Cerrado. Data contains the Environmental matrix (Q) composed of the land use classes for each samplimg site, species trait (R) matrix with content of each pigment in cells, averaged from all individuals, and species composition matrix (L) with the species incidence in all sampling sites.
    Data Types:
    • Software/Code
    • Tabular Data
    • Dataset
    • File Set
  • A method for measuring snow adhesion has been developed and tested. The present dataset represent the resulting data from this testing. Testing was performed in a controlled environment and using synthetic snow, in order to make the results as reproducible as possible. The data is structured so as to be self-explanatory given a context is provided as above, and include time and date of each sample run. This allows for analysis of the temperature and humidity stability.
    Data Types:
    • Tabular Data
    • Dataset
  • Data and R-script corresponding to the article of Fayard et al. "Magnitude and direction of parasite-induced phenotypic alterations: a meta-analysis in acanthocephalans"
    Data Types:
    • Software/Code
    • Tabular Data
    • Dataset
  • This database compiles five indicators regarding working conditions: fatal occupational injuries, non-fatal occupational injuries, forced labour, part-time employment and temporary employment. Each of the five indicators is provided for 44 regions according to WIOD Release 2016 regional structure and is disaggregated by economic activity according to the International Standard Industrial Classification of All Economic Activities (ISIC) Rev. 3. Therefore, this dataset is suitable to be introduced as a social satellite account in a multi-regional input-output model. Data has been compiled from official sources as ILOSTAT, EUROSTAT or OECD Data among others. Data coming from different databases have been homogenized, and in some cases estimation has been required. Main sources are specified in the dataset. For further information about the generation process of the dataset, please check García-Alaminos Á, Monsalve F, Zafrilla J, Cadarso MA (2020) Unmasking social distant damage of developed regions’ lifestyle: A decoupling analysis of the indecent labour footprint. PLOS ONE 15(4): e0228649. https://doi.org/10.1371/journal.pone.0228649. For any question, you can contact the author at angela.garcia@uclm.es.
    Data Types:
    • Tabular Data
    • Dataset
    • Document
  • We included aggressive, negative emotional, and neutral words in attention and memory bias tasks. The data collected in the present study reveals the characteristics of attention and memory biases of individuals with fragile high self-esteem.
    Data Types:
    • Tabular Data
    • Dataset
  • This data was collected from households with experience of flood hazards and disaster in northern Ghana using interviews and focus group discussions. It comprises both quantitative and qualitative responses from householders, seeking to measure the relationship between early warning communications and local responses to flood risk prevention. There are questions on households' knowledge of early warning communication systems, strategies and channels, households prior exposure to floods, the types of local actions adopted to mitigate flood risk and the nature of post-reconstructions interventions they have been part of. We set out to test the relationship between flood experience and households risk response behaviour using multivariate logistic regressions and bi-variate analysis such as chi-square. We found that flood experience significantly impacted the risk response adopted by householders. Similarly, the emotional state of households significantly influenced the local actions to prevent flood risk. Among the early warning communication channels adopted by disaster authorities, local FM radio proved to be more effective on the decisions of households relative to the adoption of risk mitigation measure. Despite this, based on data from 68 households and 6 separate focus groups, we found that, Early Warning information did not lead to effective local actions in disaster hot spot communities. Households were concerned about loss of properties and lives during flood disasters; nonetheless they were less likely to move away from disaster prone areas, citing factors such as inter-generational belief systems, cost of relocation, soil fertility around the riverbanks and fear of losing ancestral lands.
    Data Types:
    • Image
    • Tabular Data
    • Dataset
  • The field work was conducted on the three consecutive days, during the P. sicula mating season (end of May/beginning of June 2018), between 10:00 and 15:00 hours, under sunny and low wind conditions. Antipredator behavior was tested on 38 mainland (ML) and 34 islet (ISL) adult males.
    Data Types:
    • Tabular Data
    • Dataset
  • Data include: Sequences from parasites belong to two genera of Haemosporidia. Hematocrit and white blood cell counts from the host during the experiment. Band count and PCR score from the triplicate molecular diagnosis (before and after the MG infection)
    Data Types:
    • Sequencing Data
    • Tabular Data
    • Dataset
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