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  • Raw data / figures for manuscript
    Data Types:
    • Software/Code
    • Slides
    • Dataset
  • This dataset contains ranking, on importance and feasibility, of statements of requirements of an electronic medical records system for oncology in low and middle income countries, by different stakeholders in cancer care in this setting
    Data Types:
    • Tabular Data
    • Dataset
  • This dataset contains clustering data for statements of requirements for an electronic medical records system for oncology in low and middle income countries (LMICs). It is a matrix with similar rows and columns. The numbers indicate how often the statement in the row was put in the same cluster as the statement in the column. The clustering exercise was completed by stakeholders in oncology in LMICs.
    Data Types:
    • Tabular Data
    • Dataset
  • The data file contains variables used for descriptive purposes and analyses of between-group effects for the manscript; Effects of the Active Smarter Kids (ASK) physical activity intervention on cardiometabolic risk factors in children: a cluster-randomized controlled trial.
    Data Types:
    • Software/Code
    • Dataset
  • Data Types:
    • Other
    • Dataset
  • The Heritability of Self-Control: a Meta-Analysis Work by Y. E. Willems, N. Boesen, J. Li, C. Finkenauer and M. Bartels. Script multi-level meta-analysis heritability self-control: 20190130_meta_SC_heritability_script Data for the multilevel meta-analysis heritability self-control: 20190130_meta_SC_heritability_data
    Data Types:
    • Software/Code
    • Tabular Data
    • Dataset
  • Figure 1: We established a clonal K562 cell line with a stably integrated construct that encodes a tightly controlled inducible Cas9 nuclease. Western blot analysis of Cas9 at various time points after induction of Cas9 by Shield-1. It shows that Cas9 accumulates gradually after induction. Figure 3, 5, S3, S6: We established a variant of the ligation-mediated PCR assay for the quantification of DNA breaks at a defined location (Chailleux et al., 2014; Dai et al., 2000; Garrity and Wold, 1992). For the detection of broken DNA, we first denature the DNA and subject it to a primer extension reaction using a primer near the break site. This ensures that all cleavage sites are converted into blunt ends, even if resection of the broken ends has occurred. Next, an adaptor is ligated to the blunted DNA end, followed by PCR with one primer near the break site and a second primer that is complementary to the adaptor sequence. When analyzed on agarose gels, the samples from cells treated with sgRNA and Shield-1 yielded a band of the expected size. Figure 6: in vitro digestion by CRISPR. By PCR we first produced double-stranded DNA fragments of 600 – 1,000 bp of 3 loci in the genome. We then incubated each fragment in vitro with the respective Cas9/sgRNA complex to induce DSBs, and investigated the reaction products by agarose electrophoresis. Some samples Cas9 was subsequently denatured by two different heat treatment protocols (20 min 80 ˚C or 5 min 96 ˚C). DNA was incubated for either 2 hours or overnight.
    Data Types:
    • Tabular Data
    • Dataset
    • File Set
  • A world checklist of free-living marine Nematodes, compiled by taxonomic experts and based on peer-reviewed literature.,Nematodes constitute one of the most numerous and widespread groups of animals, inhabiting seas, fresh water, soil or living as parasites of animals and plants. Apparently simple organisms, nematodes possess astounding plasticity to adapt to a wide range of conditions and habitats. Nematodes are most widely known as parasites of plants and animals but they are even more numerous as free inhabitants of soil and water. Although nematodes look very similar in general structure, their morphology is very diverse, ranging from cylindrical to aberrant body shapes, which implies different locomotion patterns, while different mouth morphology relates to their feeding ecology. Nemys offers documentation on free-living marine, brackish, fresh-water and terrestrial nematodes, mainly providing taxonomical information but also ecological information, including literature on type species which can be consulted by the registered users of this online tool. Nemys is integrated into the World register of Marine Species (WoRMS) hosted at the Flanders Marine Institute (VLIZ), and managed by an international team of taxonomic editors with the help of the WoRMS – Aphia data management team.,
    Data Types:
    • Dataset
  • Data Types:
    • Dataset
  • Additional file 2. Search strategy for bibliographic databases.
    Data Types:
    • Document
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