Mendeley Data Showcase

Transmission trial

Diagnosing Fourth-Grade Students’ Misconceptions of Matter and Its Properties: An Integrated IRT And Latent Class Analysis Using A Four-Tier Diagnostic Test

The Upated original data material for this manuscript.

With the increasing global demand for renewable energy, offshore wind power generation has attracted great attention, especially the development of floating offshore wind turbines .Offshore floating wind turbine foundations involve multiple key dimensional parameters that strongly interact and influence the system's extreme motion response. Traditional optimization methods struggle to handle these complex couplings, necessitating AI-driven approaches like neural networks for intelligent parameter optimization. However, limited dataset availability in this emerging field poses a challenge. This paper proposes a small-sample-based optimization method for wind turbine foundation design. The HexaSemi-submersible FOWT was optimized by tuning four key parameters :column spacing (L), platform draft (T), column diameter (D), and caisson height (h). OpenFAST simulated motion responses, followed by a BP neural network modeling parameter-displacement relationships. Coupled with genetic algorithms, this approach reduced platform displacement by 16.03% versus the original design configuration.

Raw data for figures of SR-XRD patterns and Raman spectra in the manuscript by Wen et al., as "Crystallinity-dependent transformation of layered manganese oxides: implications for the mineral diversity of manganese oxides in nature".

Background: Vascular dementia (VD) is the second most common type of dementia after Alzheimer's disease, with complex pathology and high prevalence. Donepezil hydrochloride, a classic acetylcholinesterase inhibitor, has been clinically shown to improve cognitive function in VD patients. Recent studies suggest it also possesses neuroprotective and anti-inflammatory properties. Peripheral inflammation and immune dysregulation can drive neuroinflammation and cognitive impairment. Regulatory T cells (Tregs) are crucial for maintaining immune homeostasis and preventing excessive inflammation. Decreased Treg number and function have been linked to cognitive impairment in VD. However, it remains unclear whether donepezil alleviates cognitive deficits in VD by modulating peripheral Treg homeostasis and reducing peripheral inflammation. Methods: 70 patients with VD were recruited and assigned to the donepezil group, while 70 normal elderly individuals were recruited and assigned to the normal control group. Both groups underwent neurobehavioral scale testing, flow cytometry, and enzyme-linked immunosorbent assay, and correlation analysis was conducted on the test results of patients with VD. Results: Donepezil hydrochloride ameliorated cognitive impairment in VD patients, reduced apoptosis of peripheral blood lymphocyte subsets (Annexin V CD4+ and Annexin V CD8+ T cells), increases in the proportions of peripheral blood(CD3+ and CD4+ T cells, Tregs, Ki67+CD3+, Ki67+CD4+ and Ki67+CD8+ T cells, Ki67+Tregs, as well as the CD4+/CD8+ T-cell ratio). Furthermore, it decreased pro-inflammatory cytokines (IL-1β, TNF-α), and elevated anti-inflammatory cytokines (IL-2, IL-4, IL-10, IL-35, TGF-β1) in the peripheral blood. In VD patients, a strong negative correlation existed between changes in ADAS-cog scores and the proportion of Tregs. Changes in the proportion of CD4+ T cells showed a strong negative correlation with that of CD8+ T cells and a positive correlation with that of Tregs. Change in the proportion of Tregs exhibited a strong positive correlation with changes in IL-10, IL-35, and TGF-β1 levels. Conclusions: It was found that the improvement of cognitive ability in patients with VD by donepezil hydrochloride may be closely related to the increase in the proportion and function of Tregs and the reduction in peripheral inflammation levels.

The database was used to investigate whether Brazil's imports from China respond differently to the imposition of anti-dumping (AD) duties than those of other countries regarded as “market economies.” It contains Brazilian import and AD monthly data from 2007 to 2020, as well as covariates (lagged Brazilian industrial output index, exchange rate, and oil prices).