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This repository contains the processed simulation data, selected trajectories, analysis outputs, and figure-generation scripts associated with the manuscript: Glassy interphases reinforce elastomeric nanocomposites by enhancing percolation-driven volume expansion under strain In filled elastomers, nanoparticle additives can dramatically increase stiffness and toughness, yet the molecular origins of this reinforcement have remained debated for decades. A prominent idea is that strong polymer–particle attractions create “glassy bridges” that directly cement particles into a load-bearing network. The data and scripts in this repository accompany a molecular simulation study showing a different picture: glassy interphases do not primarily reinforce by directly supplying elongational cohesion. Instead, they amplify a more fundamental mechanism in which competition between particulate and elastomeric networks increases volume expansion under strain, thereby activating large bulk-modulus contributions to the response. The repository is organized around two main directories. The `data/` directory contains processed simulation outputs, selected input files, and helper scripts for reproducing simulations and post-processing analyses. The `figures/` directory contains figure-specific plotting scripts and source files for all main-text and supporting-information figures. Simulation datasets are organized by filler structure, filler loading, and filler–polymer attraction strength. For full repository documentation, directory structure, software prerequisites, and detailed workflow instructions, see the top-level `README.md`. Associated manuscript: https://arxiv.org/abs/2509.04755

Data for article: Acidogenic fermentation of tequila vinasse: Impact of operational pH on metabolic profile and microbial communities

"Dados de replicação para: Análise temporal e espacial da dengue nos municípios do Brasil: 2014 a 2024".

This systematic review was conducted to test the hypothesis that vorasidenib, a dual inhibitor of mutant IDH1 and IDH2 enzymes, improves clinical outcomes in patients with IDH-mutant low-grade gliomas (LGGs), particularly by prolonging progression-free survival (PFS), delaying the need for chemoradiotherapy, and maintaining an acceptable safety profile. The data were derived from nine clinical trials (Phase I–III) identified through a PRISMA-guided search of six major databases up to June 2025. These studies included both early-phase single-arm trials and randomized controlled trials, with sample sizes ranging from approximately 48 to 331 patients. The populations consisted mainly of adults with histologically confirmed IDH1- or IDH2-mutant gliomas, often with residual or recurrent, non-enhancing disease. Vorasidenib was administered orally at varying doses (25–300 mg/day), with later-phase trials commonly using 40–50 mg daily, and compared against placebo or alternative IDH inhibitors such as ivosidenib. Outcomes assessed included PFS, objective response rate (ORR), time to next intervention (TTNI), reduction in the oncometabolite 2-hydroxyglutarate (2-HG), and adverse events. Risk of bias was generally low, with seven studies rated as low risk and two showing some concerns related to randomization. The findings consistently demonstrate that vorasidenib significantly improves PFS, most notably in the Phase III INDIGO trial, where median PFS was 27.7 months compared to 11.1 months with placebo (HR 0.39, p < 0.001). Additionally, vorasidenib markedly delayed the need for further treatment, with 85.6% of patients remaining intervention-free at 18 months versus 47.4% in the placebo group. Early-phase studies showed that while objective tumor shrinkage was modest, disease stabilization occurred in up to 77.3% of patients, indicating a primarily cytostatic effect. Mechanistically, the drug demonstrated strong on-target activity, reducing intratumoral 2-HG levels by over 90%, thereby supporting its role in reversing metabolic and epigenetic dysregulation. Notably, efficacy was greater in non-enhancing tumors and in patients with higher variant allele frequency, suggesting a role for biomarker-driven treatment selection. In terms of safety, vorasidenib was generally well tolerated, with the most common adverse events being elevated liver enzymes, headache, and nausea. Grade ≥3 adverse events occurred in approximately 20–25% of patients but were largely manageable with dose adjustments. Overall, the data suggest that vorasidenib offers a meaningful clinical benefit by delaying disease progression and postponing the need for more toxic therapies, particularly in early-stage LGG. These findings support its use as a targeted therapeutic option and highlight its potential to shift treatment paradigms toward earlier, biology-driven intervention.

Table 1 Characteristics and size of chondrules from NWA 6991. Table 2 Summary of chondrule characteristics, counts, and SIMS analyses in NWA 6991. Table 3 Mg# and host oxygen isotopic compositions of layered (core, rim, host), barred olivine (BO), dusty olivine chondrules. Table 4 Elemental composition of core, rim, and core+rim (bulk) of layered chondrules. Table S1 Laser fluorination oxygen isotope ratios of olivine and pyroxene standard materials. Table S2 Raw-measured EPMA data. Table S3 O-isotope data of individual minerals.

This repository provides the data underlying the analyses in Unraveling a Vicious Cycle: Extreme Weather Events, Urban Expansion, and Deforestation. It contains harmonized regional panel data used to examine the interrelations between drought and flood damages, urban expansion, and tree cover loss between 2001 and 2018. The compiled datasets integrate disaster records with geospatially aggregated indicators on land cover, population, nighttime lights, conflict, and climatic conditions. The repository is designed to facilitate reproducibility and to document the empirical basis of the study. Data preparation, coding, and repository curation were carried out by Leonie Ratzke.

This dataset contains the granular analytical data supporting the Systematic Literature Review (SLR) titled "Mapping the Safety Dip: A Systematic Evidence-Unit Mapping of Performance Trajectories in Autonomous Shipping." While traditional systematic reviews analyze papers as single units, this dataset employs an Evidence-Unit Mapping (EUM) approach, deconstructing 67 high-impact studies into 158 discrete performance claims regarding safety and economic efficiency in Maritime Autonomous Surface Ships (MASS). The dataset includes (1) Source Coding: Identification of original studies (P1–P67); (2) Thematic Metadata: Categorization by IMO Degrees of Autonomy (DoA 1–4), primary area of focus, and methodological approach (Quantitative, Qualitative, Review); (3) Performance Impact Scores: Binary and weighted consensus coding (-1, 0, +1) for safety and cost-efficiency impacts; (4) Evidence Justification: A dedicated column of "Exact Quotes" from the source literature, providing the qualitative evidence used for each quantitative score.

We focus on five prevalent skin diseases in Bangladesh: Contact Dermatitis, Vitiligo, Eczema, Scabies, and Tinea Ringworm. The dataset consists of 1612 images (after augmentation), collected directly from patients at the outpatient department of Faridpur Medical College, Faridpur, Bangladesh. The data comprises of 302, 381, 301, 316, and 312 images of Dermatitis, Eczema, Scabies, Tinea Ringworm, and Vitiligo, respectively. We expect that this dataset would garner attention from machine learning and deep learning researchers and practitioners working in the field of automated disease diagnosis. In Version 2, we upload (1) the 197 raw images (i.e., before augmentation), and (2) the augmented images of size 512x512 pixels.

This spreadsheet contains data from a Q methodology project examining foreign language anxiety in relation to English-medium instruction. Data were collected from a group of university students in Turkey. All Q sorts were entered into a spreadsheet. These data are intended to be analyzed using inverted factor analysis.

Supplementary data for: Zeldenrust, E.G., Carlton, K., Jenkins, E.J., Moré, G., Nielsen, M.K., Pearl, D.L., Schott, C.R., Terier, S.M., Barta, J.R., 2026. Klossiella equi, an underreported parasite of equids in the Americas. Veterinary Parasitology, in press. (TO BE UPDATED UPON ACCEPTANCE/PUBLICATION) Sample metadata are provided for all animals from which PCR amplicons were sequenced to confirm amplicon specificity. See primary article above for details of methodology and sample collection. Supplementary Figure 1 illustrates the sequencing reads from 19 equine kidney samples (see Table 1 in 'Supplementary Data - Metadata for all sequenced samples.pdf' for specimen details and associated GenBank accession numbers) compared to the reference mitochondrial genome of Klossiella equi (Apicomplexa, Adeleorina, Klossiellidae). Supporting data includes alignments of chromatograms (Geneious format) or sequences (fasta format). Supplementary Figure 2 illustrates the sequencing reads from 5 equine kidney samples (see Table 2 in 'Supplementary Data - Metadata for all sequenced samples.pdf' for specimen details and associated GenBank accession numbers) compared to the reference mitochondrial genome of Klossiella equi (Apicomplexa, Adeleorina, Klossiellidae). Supporting data includes alignments of chromatograms (Geneious format) or sequences (fasta format).