Al Moussawi et al 2022 "Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis"

Published: 30 August 2022| Version 1 | DOI: 10.17632/23yddhm5sn.1
Contributor:
Xin Lu

Description

Raw imaging data that was used to generate the figures for Al Moussawi et al 2022 "Mutant Ras and inflammation-driven skin tumorigenesis is suppressed via a JNK-iASPP-AP1 axis". Please refer to the paper in Cell Reports for more explanation. The sequencing data generated during this study is available at GEO under SuperSeries GSE188448. Code to reproduce this analysis can be found at github.com/tcarroll/iASPP_keratinocyte_ChIPseq_RNAseq. A publicly accessible UCSC genome browser session to assist visualization of ChIP-seq results from this study is available at http://genome.ucsc.edu/s/CarrollTM/iASPP_keratinocyte_p63.

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Steps to reproduce

Please see the methods section in the paper in Cell Reports.

Institutions

Ludwig Institute for Cancer Research Oxford Branch, University of Oxford

Categories

Microscopy, Inflammation, Skin Cancer, RNA Sequencing, Immunoprecipitation, Chromatin Immunoprecipitation, Western Blot, Immunohistochemistry, Protein-DNA Interaction, P53, Papilloma, Quantitative Reverse Transcription Polymerase Chain Reaction

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