The Effect of Neutrophil-to-Lymphocyte Ratio, Monocyte-to-Lymphocyte Ratio, and Platelet-to-Lymphocyte Ratio towards Neonatal Outcome in Pregnancies with Preeclampsia or Eclampsia: A Prospective Cross Sectional
Description
Background: Preeclampsia still causes high maternal and perinatal mortality and morbidity. Uteroplacental insufficiency in preeclampsia is related with fetal low birth weight, preterm birth and neonatal asphyxia. Neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR) and platelet-to-lymphocyte ratio (PLR) may be useful in predicting neonatal outcome in preeclampsia. Objective: This study aims to investigate these markers in predicting neonatal outcome in preeclampsia. Methods: This prospective cross sectional study was conducted in 35 normal, 35 preeclampsia, and 35 eclampsia patients. NLR, MLR and PLR were analyzed against preterm and asphyxia status. Result: There is a significant difference between NLR (p<0.001), MLR (p<0.001) and PLR (p<0.001) against preterm status and there is significant difference between NLR (p <0.001), MLR (p<0.001) and PLR (p<0.001) against asphyxia status. Conclusion: Higher NLR, MLR, and PLR is associated with worse pregnancy outcomes, including asphyxia and preterm birth.