Supplementary Figure 1. DOX induces cardiac and skeletal muscle wasting.

Name: Supplementary Figure 1. DOX induces cardiac and skeletal muscle wasting.
Creator: Kasia Dzierlega
Published: 2026-02-19T12:23:23.020Z
Keywords: Immunology, Cardiomyopathy, Neutrophil Response

Dzierlega, Kasia; Soliman, Amro; Chen, Huachen; Vu, Jennie; Parker, Derek; Roberts, Blake; Wagner, Mitchell; Akter, Aklima; Hassane, Maya; Kilic, Tolga; Wong, Jonas; Akbari, Masoud; Elhenawy, Wael; Oudit, Gavin; Tsai, Sue; Clemente-Casares, Xavier

doi:10.17632/2d8stp2tpg.2

Supplementary Figure 1. DOX induces cardiac and skeletal muscle wasting.

Published: 19 February 2026| Version 2 | DOI: 10.17632/2d8stp2tpg.2

Contributors:

Kasia Dzierlega,

,

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Percentage of body weight change (A), grip strength (B), quadriceps weight to tibia length ratio (MW/TL) (C), percentage change of MW/TL (D), heart weight to tibia length ratio (HW/TL) (E) and percentage change of HW/TL (F) of control (labeled ‘C’) and DOX-treated mice (n=5). (G) Representative image of heart and quadriceps sections from control and DOX mice stained with wheat germ agglutinin (WGA). (H-I) Cross-sectional analysis of myocytes in heart (H) and quadriceps (I) of control and DOX-treated mice. Violin plots show the spread of data with a dashed line representing the median; (n=3). (J-K) Normalized expression of FBXO32 and TRIM63 to Gapdh in cardiac tissue of control and DOX-treated mice (n=5).

Supplementary Figure 1. DOX induces cardiac and skeletal muscle wasting.

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