Effects of Cranial Base Release and Upper Cervical Spine Mobilization in Patients with Migraine Headache: A Two group pretest posttest randomized pilot clinical trial

Published: 15 June 2020| Version 1 | DOI: 10.17632/2y3bdtwdmb.1


BACKGROUND: Migraine is a common chronic disorder causing recurrent attacks and thus resulting in severe complications. Patients with migraine headache suffer with reduced quality of life in turn having low productivity in workplaces, causing a burden on them. AIM: The aim of the study is to determine the effects of Cranial base release (CBR) combined with upper cervical spine mobilization and CBR only in patients with migraine. MATERIALS AND METHODS: A two group pre post pilot study was conducted. Total numbers of 12 patients suffering with migraine headache were recruited for the study. Age group of the patients is taken from 18-30 years. Patients were randomly allocated in two groups - Group A and Group B. In group A, Cranial Base Release with upper cervical spine Mobilization at (C0-C3) were given as a treatment while in group B only Cranial Base Release was as a treatment. In both the groups, treatment duration was 20 minutes for 2 weeks, 6 sessions were given for alternate days. Outcome measures used for Pre-test Post-test comparison were Pressure Algometer for measuring Pain Pressure Threshold and Headache Disability Index (HDI) for calculating Disability Index. RESULTS: To determine the normality Shapiro Wilk was used, as the sample size was less than 50. Data following normal distribution. Paired t test was used for within the group analysis and Independent t test was used for between the group analysis. Effect size was calculated form Effect Size Index. No statistically significant difference were noted in post Headache Disability Index and Algometer values (P>0.05). Effect size predicts huge effect size in post HDI values in Group 1 as compared with the group 2. CONCLUSION: Both the treatments help in reducing pain and disability in patients suffering with migraine.



Maharishi Markandeshwar Institute of Physiotherapy and Rehabilitation


Migraine, Headache, Cranial Osteopathy, Chronic Pain