Elucidation of E3 Ubiquitin Ligase Specificity . Zhang et al.Through Proteome-wide Degron Mapping. Zhang et al.

Published: 6 March 2023| Version 1 | DOI: 10.17632/32h94v2yv2.1
Contributors:
Zhiqian Zhang,
Brandon Sie,
Aiquan Chang,
Yumei Leng,
Stephen Elledge

Description

This repository contains sequencing data related to "Elucidation of E3 Ubiquitin Ligase Specificity Through Proteome-wide Degron Mapping" by Zhang et al. Data is included for the GPS peptidome screen with and without MLN, results from the composition-based SVM machine learning model, along with sequencing data for scanning and saturation mutagenesis degron footprints, and from CRISPR screens for identification of E3-degron pairs.

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Institutions

Brigham and Women's Hospital, Harvard Medical School

Categories

Protein Degradation

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