Dataset for Limit of Detection of Raman Spectroscopy Using Polystyrene Particles from 25 to 1000 nm in Aqueous Suspensions
Published: 27 March 2025| Version 1 | DOI: 10.17632/33wf5rtr4h.1
Contributors:
Cindy Mayorga, SHREYA MILIND ATHALYE, Miad Boodaghidizaji, Neelesh Sarathy, Mahdi Hosseini, Arezoo Ardekani, Mohit VermaDescription
We systematically studied the limit of detection of confocal Raman spectroscopy using polystyrene particles in a range of 25-1000 nm as models for sizes of viruses, viral particles and aggregates. Our results demonstrated that Raman spectroscopy can detect particles as small as 50 nm at a limit of detection of 1.80 x 10^12 - 8.31 x 10^12 particle/mL, and for the largest size of 1000 nm, 5.11 x 10^8 - 2.53 x 10^9 particle/mL. In this dataset, we have included the raw and processed data files associated with the results of this manuscript.
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Institutions
- Purdue University
Categories
Raman Spectroscopy, Dynamic Light Scattering