Target predictions for abundantly secreted nematode microRNAs

Published: 26 October 2021| Version 1 | DOI: 10.17632/358nm9mhpr.1
Lucienne Tritten


Host (mouse) targets of the 20 most abundantly secrected miRNAs of Heligmosomoides polygyrus bakeri, Trichuris muris, and Ascaris suum were predicted computationally with TargetScan v.7.


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Secreted miRNA lists from H. polygyrus bakeri, T. muris, and A. suum were retrieved from the literature (Hansen et al. 2019 (doi: 10.1080/20013078.2019.1578116); Eichenberger, Talukder, et al. 2018 (doi: 10.1080/20013078.2018.1428004); Tritten et al. 2017 (doi: 10.1016/j.exppara.2017.05.003); Buck et al. 2014 (doi: 10.1038/ncomms6488)). Target prediction in the mouse genome for the top 20 most abundant miRNAs was performed as described previously (Duguet et al. 2020) using the TargetScan software package v. 7 (, using default parameters (Agarwal et al. 2015 (doi: 10.7554/eLife.05005)).


Universitat Zurich


Parasitology, Nematoda, MicroRNA, Host-Parasite Interaction