Dataset of fraction unbound values in the in vitro incubations

Published: 9 February 2024| Version 1 | DOI: 10.17632/3bs5526htd.1
Contributor:
Laura Krumpholz

Description

Database containing information on fraction unbound in human or animal plasma, hepatocytes, microsomes and recombinant cytochromes. Data on a free fraction in plasma and different in vitro models are supplemented with the following information: the experimental method used for the assessment of the degree of drug binding, protein or cell concentration in the incubation, and other experimental conditions, if different from the standard ones, species, reference to the source publication, and the author's name and date of publication.

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Institutions

Uniwersytet Jagiellonski w Krakowie Collegium Medicum

Categories

Binding Protein, Liver Microsome, Cytochrome P450, Hepatocyte, Extrapolation, In Vitro Techniques

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