Published: 01-01-2017| Version 1 | DOI: 10.17632/3jtdnyjzfm.1
J Bertran-Gonzalez


\Data type and description: event-time stamp data. The time at which each event occurred (Y matrix, values 1-4) was stamped with a 10 ms resolution (Z matrix, centiseconds). Y matrix: 1=active response; 2=inactive response; 3=delivered pellet; 4=Magazine entry (time-controlled; consecutive entries within 200ms are not repeatedly stamped). Data were obtained through MED STATE NOTATION (MED Associates)


Steps to reproduce

\Experiment summary: 15 aged mice (Lost (L) and Maintained (M); C57Bl6/J 20-22 months old) were submitted to instrumental training (increasing random ratio schedule of reinfocement). CRF (days 1-3): constant reinforcement; RR5 (days 4-6): random ratio 5; RR10 (days 7-12): random ratio 10; RR20 (days 13-36): random ratio 20. Active lever counterbalanced (Left [L] or Right [R]). \Penalising regime: from day 10 of training, a penalising protocol was introduced (pen5). From day 13, this regime was increased to pen7. Pen5: If the last 5 actions are not LP, probability of reward delivery is reseted; Pen7: If the last 7 actions are not LP, probability of reward delivery is reseted. \The last element of each sequece providing the reward was signalled with a 0.75s white noise in all mice. From day 19 onwards , animals marked with L (group Lost) stopped receiving such cue (see asterisks on data), and were run on the second session to prevent cue bleed through. \NOTE: subject R6_L reduced performance on day 29 and was retired from the experiment (died on day 31).