Published: 1 January 2017| Version 1 | DOI: 10.17632/3jtdnyjzfm.1
J Bertran-Gonzalez


\Data type and description: event-time stamp data. The time at which each event occurred (Y matrix, values 1-4) was stamped with a 10 ms resolution (Z matrix, centiseconds). Y matrix: 1=active response; 2=inactive response; 3=delivered pellet; 4=Magazine entry (time-controlled; consecutive entries within 200ms are not repeatedly stamped). Data were obtained through MED STATE NOTATION (MED Associates)


Steps to reproduce

\Experiment summary: 15 aged mice (Lost (L) and Maintained (M); C57Bl6/J 20-22 months old) were submitted to instrumental training (increasing random ratio schedule of reinfocement). CRF (days 1-3): constant reinforcement; RR5 (days 4-6): random ratio 5; RR10 (days 7-12): random ratio 10; RR20 (days 13-36): random ratio 20. Active lever counterbalanced (Left [L] or Right [R]). \Penalising regime: from day 10 of training, a penalising protocol was introduced (pen5). From day 13, this regime was increased to pen7. Pen5: If the last 5 actions are not LP, probability of reward delivery is reseted; Pen7: If the last 7 actions are not LP, probability of reward delivery is reseted. \The last element of each sequece providing the reward was signalled with a 0.75s white noise in all mice. From day 19 onwards , animals marked with L (group Lost) stopped receiving such cue (see asterisks on data), and were run on the second session to prevent cue bleed through. \NOTE: subject R6_L reduced performance on day 29 and was retired from the experiment (died on day 31).


The University of Queensland Queensland Brain Institute


Aging, Operant Conditioning, Learning Instruction, Action Learning, Sequence Learning